Some cross-reactivity exists between the 65-kd hsp and the 60-kd human mitochondrial hsp. (medscape.com)
RAS thus may be a T cell-mediated response to antigens of S sanguis , which cross-react with the mitochondrial hsp and induce oral mucosal damage. (medscape.com)
Genes2
Genes for endoplasmic reticulum (ER)-shaping proteins are among the most commonly mutated in hereditary spastic paraplegia (HSP). (frontiersin.org)
Hereditary spastic paraplegia (HSP) is a genetically heterogeneous disorder, with over 80 loci and 60 genes identified. (frontiersin.org)
Spastic paraparesis2
Diagnostic criteria for HSP included (i) spastic paraparesis or spastic tetraparesis with legs earlier and more severely affected than arms or (ii) spastic paraparesis as early and prominent sign of a neurodegenerative multisystem disease after exclusion of other causes. (biomedcentral.com)
The present study is an examination of possible subclinical involvement of lower motor neuron (LMN) in patients with primary lateral sclerosis (PLS) and hereditary spastic paraparesis (HSP) electrophysiologically. (hspersunite.org.au)
Hereditary1
128 patients (58 women, 70 men) from 109 families were recruited by specialised HSP outpatient clinics in Bochum, Kiel, and Tübingen, Germany, in the context of the German Network of Hereditary Movement Disorders (GeNeMove). (biomedcentral.com)
Cross-reactivity3
No significant cross-reactivity or interference between Rat HSP-60 and analogues was observed. (caslab.com)
Cross-reactivity between a streptococcal 60- to 65-kd heat shock protein (hsp) and the oral mucosa has been demonstrated, and significantly elevated levels of serum antibodies to hsp are found in patients with RAS. (medscape.com)
P. gingivalis HSP60 is reported to accelerate the development of experimental atherosclerosis by cross-reactivity of the immune response to bacterial HSPs ( 19 ). (spandidos-publications.com)
Monoclonal2
Two monoclonal antibodies generated against human hsp60 show reactivity with synovial membranes of patients with juvenile chronic arthritis. (silverchair.com)
We have developed murine monoclonal antibodies after immunization with recombinant human hsp60. (silverchair.com)
Electrophysiologically1
We clinically and electrophysiologically examined a cohort of 128 patients with genetically confirmed or clinically probable HSP. (biomedcentral.com)
Serum1
This CLIA kit applies to the in vitro quantitative determination of Rat HSP-60 concentrations in Serum, plasma and other biological fluids. (caslab.com)
Induce1
These results indicated that P. gingivalis HSP60 may induce dysfunction and apoptosis in HUVECs via downregulating the expression levels of VE‑cadherin and eNOS, and promoting the cleavage of caspase‑3. (spandidos-publications.com)
Sequences1
He has authored over 350 peer-reviewed papers and book chapters and is co-recipient of several US and international patents on the use of the 60 kDa heat shock protein (HSP60) gene sequences as universal targets for infectious disease diagnosis and microbial species identification. (cdc.gov)
Buggy1
Win races and dominate the off-road with the HSP Nitro Power Off Road Buggy. (rc-cars.store)
Degeneration2
Our lines are useful additions to a Drosophila Ca 2+ imaging toolkit, to explore the physiological roles of ER, and its pathophysiological roles in HSP and in axon degeneration more broadly. (frontiersin.org)
Our previous study suggests the critical role of heat shock protein 60 (HSP60) in IL-1β-induced inflammation in microglia through TLR4-p38 MAPK axis. (biomedcentral.com)
HSP60 further activates NLRP3 inflammasome by elevating NLRP3 expression both at RNA and protein levels. (biomedcentral.com)
The aim of the present study was to identify whether P. gingivalis heat‑shock protein 60 (HSP60) induced the dysfunction of human umbilical vein endothelial cells (HUVECs) in vitro. (spandidos-publications.com)
P. gingivalis HSP60 at a concentration of 10 ng/l significantly decreased the expression levels of VE‑cadherin and eNOS protein at 24 h stimulation, whereas no difference in these proteins was identified following a low dose of P. gingivalis HSP60 (1 ng/l). (spandidos-publications.com)
P. gingivalis HSP60 at 100 ng/l significantly downregulated the expression levels of VE‑cadherin and eNOS protein at 12 h in HUVECs. (spandidos-publications.com)
Furthermore, atherosclerosis can be triggered and aggravated by the pathogen-driven antigenic peptide from P. gingivalis heat-shock protein 60 (HSP60) ( 15 - 17 ). (spandidos-publications.com)
Methods1
Herein, we tested a 60- biomarker health surveillance panel (HSP), containing 35 FDA/LDT assays and covering at least 14 pathological states, on 8 healthy individuals' ability to collect their own capillary blood from a lancet finger prick and directly compared it to the traditional phlebotomist venous blood and plasma collection methods . (bvsalud.org)
Dysfunction1
Signs of lower motor neuron dysfunction were found in this study of people with HSP and PLS via electrophysiological markers. (hspersunite.org.au)
Pairs1
Potential pairs with blocking were present in HSP group (7 of 100 potential pairs) but not seen in PLS patients. (hspersunite.org.au)
Temperature1
Head and Dome Top versions are IP65 (Plain Holes) and IP66 (Threaded Holes) and have an operating temperature of -60°C to +80°C. (rs-online.com)
Disorder1
Whereas HSP is primarily considered as an upper motoneuron disorder, our data suggest a more widespread affection of motor and sensory tracts in the central and peripheral nervous system as a common finding in HSP. (biomedcentral.com)
Scale1
Built to withstand rough off-road surfaces, this HSP 1/10 scale car is strong and robust, making it a favorite among racing enthusiasts. (rc-cars.store)
Human4
In human arthritis and in experimentally induced arthritis in animals, disease development was seen to coincide with development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homologue. (silverchair.com)
Antibodies with unique specificity for mammalian hsp60, not crossreactive with the bacterial counterpart (LK1), and antibodies recognizing both human and bacterial hsp60 (LK2) were selected. (silverchair.com)
Both antibodies recognize epitopes located between amino acid positions 383 and 447 of human hsp60. (silverchair.com)
An overall 55% homology exists between human and bacterial HSP60 that can even reach 72% at certain domains of the 573-amino-acid-long molecule ( 18 ). (spandidos-publications.com)
Group1
HSP comprises a group of twelve models, eight 1000 watt power supplies with outputs from 3.3 volts to 125 volts and four 1500 watt power supplies with outputs from 15 volts to 125 volts. (kepcopower.com)
Significant2
43 microseconds) observed in the PLS and HSP groups was 16/180 and 9/100, respectively without a significant intergroup difference. (hspersunite.org.au)
HSP in Brazil has mobilised significant actions, even though it has not happened in homogeneously in all Brazilian regions. (bvsalud.org)
Patients4
We set out for an electrophysiological characterisation of motor and sensory tracts in patients with HSP. (biomedcentral.com)
Electrophysiological features of HSP have been studied in rather small cohorts (maximum of 26 patients per study) with poor genetic characterisation. (biomedcentral.com)
To analyse the spread of long fibre tract affection in HSP and to explore potential effects of different pathomechanisms in distinct genotypes we studied motor and sensory involvement of the central and peripheral nervous system by clinical and electrophysiological means in a representative cohort of HSP patients. (biomedcentral.com)
Nine PLS patients and 5 HSP patients were prospectively analyzed. (hspersunite.org.au)
Series3
The Kepco HSP series provides mission critical power. (kepcopower.com)
Models with the or-ing diode, option R, are capable of hot swapping when plugged into Kepco s RA 60 series rack adapter. (kepcopower.com)
For HSP reliability in harsh, wet and unusual environments, see Kepco's KHX Series of fault tolerant power supplies. (kepcopower.com)
Study1
Additionally, in a clinical study, a strong positive correlation was found between high levels of soluble HSP60 and the risk of CAD ( 21 ). (spandidos-publications.com)
Modules1
All HSP modules are suitable as DC-DC converters, however note that Safety Agency approvals are valid only for a-c input. (kepcopower.com)
Samples3
You can calculate the concentration of Rat HSP-60 in the samples by comparing the RLU value of the samples to the standard curve. (caslab.com)
This kit recognizes Rat HSP-60 in samples. (caslab.com)
All samples were spiked with 114 stable- isotope -labeled (SIL) HSP peptides and quantitatively analyzed by liquid chromatography -multiple reaction monitoring - mass spectrometry (LC/MRM-MS) scheduled method targeting 466 transitions from 114 HSP peptides and by a discovery data-independent acquisition mass spectrometry (DIA-MS) method . (bvsalud.org)
Panel1
Assessment of a 60-Biomarker Health Surveillance Panel (HSP) on Whole Blood from Remote Sampling Devices by Targeted LC/MRM-MS and Discovery DIA-MS Analysis. (bvsalud.org)
Range2
The 1000 watt HSP have a wide range a-c input (90-277V a-c). (kepcopower.com)
HUVECs were stimulated with a range of P. gingivalis HSP60 concentrations (1, 10 and 100 ng/l) at different time‑points. (spandidos-publications.com)
Common1
These studies point to the importance of a continuous and connected tubular ER network throughout axons and presynaptic terminals and suggest disruption to this network as a common thread in HSP pathogenesis. (frontiersin.org)
Models1
Headlight Lens Gaskets For All 1929-30 + 1931 Ser.60-80-90 & 1932-33 All Models. (bobsautomobilia.com)
Product1
The following product was used in this experiment: HSP60 Polyclonal Antibody from Thermo Fisher Scientific, catalog # PA5-143265. (thermofisher.com)
Period of t1
In terms of the HSP condition, I guess for a long period of time, I maintained a denial stage in accepting the condition. (hspersunite.org.au)
Long1
Headlight Badge Bar In Stainless 17-1/4″Long For All 1930 + 1931 Ser.60-80-90. (bobsautomobilia.com)
Kits1
Motorcycle Cylinder Block & Kits_Motorcycle Cylinder Block & Kits_HSP: Experienced cylinder & engine parts manufacturer in China. (hspcylinder.cn)