• Polymorphisms in HSD17B2 have been associated with breast cancer and prostate cancer. (wikipedia.org)
  • 13 GAO X,DAI C,HUANG S,et al.Functional silencing of HSD17B2 in prostate cancer promotes disease progression J .Clin Cancer Res,2019,25(4):1291-1301. (xdzlyx.com)
  • The percentage of tumor samples showing BRCA1, HSD17B1 and HSD17B2 methylation was 20.4%, 83.3% and 31.3%, respectively. (nih.gov)
  • We examined possible associations between serum sex hormone level and polymorphisms in CYP19A1, HSD17B1, and HSD17B2. (elsevierpure.com)
  • 5. Polymorphisms in genes HSD17B1 and HSD17B2 and uterine leiomyoma risk in Chinese women. (nih.gov)
  • Polymorphisms in HSD17B2 have been associated with breast cancer and prostate cancer. (wikipedia.org)
  • Four tag SNPs (single nucleotide polymorphisms) of CYP19A1, one missense SNP of HSD17B1 and three tag SNPs of HSD17B2 were examined by Invader assay. (elsevierpure.com)
  • Conclusions Our findings suggested that CYP19A1 and HSD17B2 polymorphisms might be associated with circulating sex hormone levels in Japanese postmenopausal women, independent of current BMI. (elsevierpure.com)
  • The present study assessed the methylation status of three genes relevant in breast cancer (BC): The breast cancer susceptibility gene 1 (BRCA1), 17 beta hydroxy steroid dehydrogenase type 1 (HSD17B1) and type 2 (HSD17B2). (nih.gov)
  • BRCA1 and HSD17B2 genes may increase the risk of developing BC via enhanced estradiol activity. (nih.gov)
  • 17β-Hydroxysteroid dehydrogenase 2 (17β-HSD2) is an enzyme of the 17β-hydroxysteroid dehydrogenase (17β-HSD) family that in humans is encoded by the HSD17B2 gene. (wikipedia.org)
  • No article was found for Obesity and HSD17B2[original query] . (cdc.gov)
  • Results After adjustment for multiple comparisons, we found that rs4441215 and rs936306 in CYP19A1 and rs4888202 and rs2955160 in HSD17B2 were associated with differences in serum estrone level. (elsevierpure.com)