Hpai h5n1. Medical search. Frequent questions

that are currently circulating in wild birds and poultry in much of the world are genetically different from earlier versions of the virus and emerged to become the predominant subtype of HPAI H5 in the fall of 2021. (cdc.gov)
Hooded vultures could potentially be vectors or sentinels of influenza subtype H5N1, as are cats and swans elsewhere. (cdc.gov)
On April 3, influenza A (subtype H5N1) was first confirmed in Burkina Faso. (cdc.gov)
The emergence and unfold of extremely pathogenic avian influenza (HPAI) A virus subtype H5N1 in Asia, Europe and Africa has had an enormously socioeconomic influence and presents an vital risk to human well being due to its environment friendly animal-to-human transmission. (flugenome.org)
See Influenza for details about the illnesses and Influenza A virus subtype H5N1 and Influenza A virus subtype H3N2 for details about the causative agents. (wikipedia.org)
Fujian flu refers to flu caused by either a Fujian human flu strain of the H3N2 subtype of the Influenza A virus or a Fujian bird flu strain of the H5N1 subtype of the Influenza A virus. (wikipedia.org)
CIDRAP says "A new subtype of H5N1 avian influenza virus has become predominant in southern China over the past year, possibly through its resistance to vaccines used in poultry, and has been found in human H5N1 cases in China, according to researchers from Hong Kong and the United States. (wikipedia.org)
Highly pathogenic avian influenza (HPAI) subtype H5N1 virus infections are constantly monitored worldwide because of their devastating effects on poultry. (usda.gov)
Unusually, in the spring of 2022, the HPAI virus (subtype H5N1) spread into our globally important colonies of nesting seabirds. (bto.org)
A sample from each location has tested positive for the highly pathogenic avian influenza (HPAI), subtype H5N1. (gov.mb.ca)
Influenza virus was isolated from lung, liver, kidney, and urine specimens, and the viral subtype was determined to be H5N1 by reverse transcription (RT)-PCR ( 6 ). (flu.org.cn)
The subtype behind the 2009 'swine flu' pandemic is H1N1, which has the same version of neuraminidase as H5N1, but a different version of hemagglutinin. (scientificamerican.com)
In October 2020, a new lineage of a clade 2.3.4.4b HPAI virus of the H5 subtype emerged in Europe, resulting in the largest global outbreak of HPAI to date, with unprecedented mortality in wild birds and poultry. (bvsalud.org)

The only people who use its full name-H5N1-HPAI-clade 2.3.4.4b-are typically scientists who study emerging viruses, such as Nichola Hill at the University of Massachusetts Boston. (motherjones.com)
In a recent study published in the CDC's Emerging Infectious Diseases journal, researchers characterized the pathophysiology of infection by the highly pathogenic avian influenza (HPAI) A (H5N1) viral organism belonging to the Eurasian lineage and 2.3.4.4b clade in non-domesticated terrestrial animals across the United States (US) between 1 April and 21 July 2022. (news-medical.net)
The team built phylogenetic interpretation trees and single-nucleotide polymorphism (SNP) tables using a reference including six segments from the H5N1 clade 2.3.4.4b virus and two from non-domesticated avian viruses from the northern regions of America. (news-medical.net)
The identified viruses belong to clade 2.3.4.4b, genotype CH (H5N1 A/Eurasian wigeon/Netherlands/3/2022-like). (eurosurveillance.org)
CDC is actively working on the domestic situation with clade 2.3.4.4b HPAI A(H5N1) viruses in wild birds and poultry outbreaks, including conducting surveillance among people with relevant exposures and preparing for the possibility that contemporary HPAI A(H5N1) viruses gain the ability for increased transmissibility to people. (cdc.gov)
H5 candidate vaccine viruses (CVV) produced by CDC are expected to provide good protection against current clade 2.3.4.4b HPAI A(H5N1) viruses in birds and mammals. (cdc.gov)
Clade 2.3.4.4b HPAI A(H5N1) viruses emerged in 2020 and were introduced into North America in late 2021 [ 1,2 ] and have spread to Central and South America, resulting in wild bird infections (in terrestrial, seabird, shorebird, and migratory species) and poultry outbreaks in many countries [ 3-8 ]. (cdc.gov)
Globally, this 2.3.4.4b clade of HPAI A(H5N1) viruses has become widespread causing record numbers of bird outbreaks in wild, backyard, village, and farm birds. (cdc.gov)

The 1997 bird outbreak was controlled, but the H5N1 bird flu viruses were not eradicated in birds and re-surfaced in 2003 to spread widely in birds throughout Asia, and later in Africa, Europe, and the Middle East, causing poultry outbreaks and sporadic human infections. (cdc.gov)
On February 7, 2006, the first African outbreak of highly pathogenic avian influenza (HPAI) (H5N1) virus was reported from a farm in Kaduna State, northern Nigeria. (cdc.gov)
Learn more about the current worldwide outbreak of the HPAI H5N1 Avian Flu. (unmc.edu)
Over a 3-week period in late June/early July 2023, Poland experienced an outbreak caused by highly pathogenic avian influenza (HPAI) A(H5N1) virus in cats. (eurosurveillance.org)
Talks described the current outbreak of highly pathogenic avian influenza (HPAI - H5N2) epidemic in the Oudtshoorn area and the vigorous systematic response by the Animal Health Division of the Dept of Agriculture, the ongoing HPAI - H5N1 epidemic in Asia and Eastern Mediterranean region and H5N1 in humans and other flu viruses of this season. (sun.ac.za)
The last HPAI outbreak in Vet Nam was reported in August this year. (thepoultrysite.com)
On February 9, 2022, USDA APHIS confirmed the first outbreak of HPAI A(H5N1) virus in a commercial turkey flock in Indiana [2]. (cdc.gov)
This discovery follows an ongoing HPAI outbreak affecting seabirds on Rat and Marrowstone Islands in Washington since mid-summer. (thewhaletrail.org)
We report a fatal H5N1 infection in a dog following ingestion of an H5N1-infected duck during an outbreak in Thailand in 2004. (flu.org.cn)
The ongoing outbreak of highly pathogenic avian influenza (HPAI) H5N1 in South Africa, which began in April 2021, has led to the culling of nearly 3 million birds, primarily layers. (usda.gov)
In response to the global outbreak in birds of highly pathogenic avian influenza (HPAI) A(H5N1), the Centers for Disease Control and Prevention (CDC) and the California Department of Public Health (CPDH) are encouraging continued testing for influenza this summer among persons with severe respiratory illness or who are exposed to poultry or swine. (ca.gov)

Evaluating the impact of environmental temperature on global highly pathogenic avian influenza (HPAI) H5N1 outbreaks in domestic poultry. (flugenome.org)
The outcomes confirmed that greater environmental temperature was a major threat issue for earlier incidence of HPAI H5N1 outbreaks in home poultry, particularly for a temperature of 25 °C. Its influence various with epidemic waves (EWs), and the magnitude of the influence tended to extend over EWs. (flugenome.org)
VIET NAM - Three new outbreaks of highly pathogenic avian influenza (HPAI) have been reported in two northern provinces. (thepoultrysite.com)
The report describes three new outbreaks of HPAI, all starting on 18 November and in village flocks. (thepoultrysite.com)
Since then, APHIS has identified 247 HPAI A(H5N1) outbreaks among commercial poultry or backyard bird flocks in 29 states involving more than 35 million birds. (cdc.gov)
Ancestors of HPAI A(H5N1) viruses first emerged in southern China and led to large poultry outbreaks in Hong Kong in 1997, which resulted in 18 human infections. (cdc.gov)
Previous outbreaks of HPAI have tended to hit wintering waterfowl, subsiding as wintering flocks disperse. (bto.org)
In 2003, outbreaks of the highly pathogenic avian influenza (HPAI) H5N1 virus had a major negative impact on the global poultry industry. (usda.gov)
In 2006, the world poultry industry was again under pressure due to HPAI H5N1 outbreaks, this time in Europe. (usda.gov)
With new reports of H5N1 virus continuing across Asia, Europe, and Africa, this finding highlights the need for monitoring of domestic animals during outbreaks. (flu.org.cn)
Outbreaks of low and high pathogenic avian influenza (LPAI, HPAI) H5N2 in chickens have occurred in Taiwan since 2003 and 2012, respectively. (biomedcentral.com)
The two-stage survey (before and after HPAI H5N2 outbreaks) was conducted from 2007 to 2012, including: (1) 430 LPMWs and 418 CRs at LPMs from different geographical areas of Taiwan after the government announced outbreaks of LPAI H5N2 during 2007-2009, and (2) 73 LPMWs and 152 CRs at two LPMs in central Taiwan after the HPAI H5N2 outbreaks in 2012. (biomedcentral.com)
Before HPAI-H5N2 outbreaks, higher educated respondents demonstrated greater risk awareness and concerns regarding AI. (biomedcentral.com)
However, because of the potential for influenza viruses to rapidly evolve and the wide global prevalence of HPAI A(H5N1) viruses in wild birds and poultry outbreaks, continued sporadic human infections are anticipated. (cdc.gov)
Over 17,000 animal outbreaks of HPAI A(H5N1) viruses were reported by 80 member countries to the World Organisation for Animal Health since January 2022. (cdc.gov)
The interspecies transmission of highly pathogenic avian influenza (HPAI) virus to poultry populations often results in devastating disease outbreaks. (who.int)

To develop on this and higher perceive how pre-exposure to heterosubtypic low-pathogenic avian influenza (LPAI) viruses may affect the result of H5N1 HPAI an infection, we pre-exposed naïve juvenile Canada Geese to completely different North American wild-bird-origin LPAI viruses. (flugenome.org)
In distinction, Canada Geese that had been pre-exposed to H1N1 had been protected in opposition to a deadly H5N1 problem, shed minimal quantities of the virus into the atmosphere, and didn't transmit the an infection to naïve contact birds. (flugenome.org)
The scale of HPAI H5N1 virus infection in cats in Poland is worrying. (eurosurveillance.org)
Additionally, differences were also observed in clinical disease after infection with a H5N1 HPAI virus, and the ducks innate immune responses also differed. (usda.gov)
Here, we report a case of HPAI H5N1 infection in a domestic dog following ingestion of the carcass of an infected duck. (greenmatters.com)
Small flocks are considered at high risk for HPAI infection as they often have access to outdoor pens or free range. (gov.mb.ca)
As of January 2012, HPAI H5N1 virus caused 577 laboratory-confirmed human cases of infection, of which 340 were fatal. (flutrackers.com)
We evaluate the dispersive potential of HPAI H5N1 viruses by wildfowl through an analysis of the movement range and movement rate of birds monitored by satellite telemetry in relation to the apparent asymptomatic infection duration (AID) measured in experimental studies. (britishecologicalsociety.org)
Our results indicate that individual migratory wildfowl have the potential to disperse HPAI H5N1 over extensive distances, being able to perform movements of up to 2900 km within timeframes compatible with the duration of asymptomatic infection. (britishecologicalsociety.org)
However, the likelihood of such virus dispersal over long distances by individual wildfowl is low: we estimate that for an individual migratory bird there are, on average, only 5-15 days per year when infection could result in the dispersal of HPAI H5N1 virus over 500 km. (britishecologicalsociety.org)
Regardless of novel LPAI or HPAI virus reassortants that pose public health risks, prompt and clear risk communication focusing on both correct information about AIVs and the most appropriate preventive measures are important for effective prevention of human infection. (biomedcentral.com)
3 Death caused by infection and preventive measures (such as depopulation) implemented to control the spread of the HPAI H5N1 virus resulted in considerable socioeconomic burdens for many of the affected countries. (who.int)

In the present study, researchers presented a series of cases to highlight the pathophysiology of spontaneous HPAI H5N1 infections among terrestrial wild animals in the US, which coincided with elevated levels of highly pathogenic avian influenza viruses in circulation among non-domesticated avian species during summer and spring of 2022. (news-medical.net)
HPAI was identified in 67 non-domesticated animals across 10 US states between April and July 2022, including 50 red-colored foxes, six striped skunks, four raccoons, two bobcats, two Virginia opossums, one coyote, one fisher, and one gray fox. (news-medical.net)
During January 13, 2022, through April 27, 2022, USDA APHIS reported more than 899 detections of wild birds infected with HPAI A(H5N1) virus in 33 states [1]. (cdc.gov)
On April 20, 2022, an adult in Colorado developed fatigue following exposure to presumptive H5N1 virus-infected poultry while participating in poultry depopulation activities during April 18-22, 2022. (cdc.gov)
As of April 26, 2022, about 33 million farmed birds have contracted the H5N1 bird flu virus, while almost 800 wild birds have been infected, as well. (greenmatters.com)
In the United Kingdom, there have been 182 confirmed cases of highly pathogenic avian influenza (HPAI) H5N1 since 1 October 2022. (thestar.co.uk)
We report and describe infections by HPAI H5N1 virus in 2 black bears (Ursus americanus) found in Quebec, Canada, during the summer of 2022. (flutrackers.com)
As of Jan. 18, 2023, data from the USDA shows that HPAI H5N1 had been detected in at least 6,192 individual wild birds in 50 states and the District of Columbia since January of 2022. (sdhumane.org)
A small number of sporadic human cases of A(H5N1) have been identified since 2022, despite the panzootic of highly pathogenic avian influenza (HPAI) A(H5N1) viruses in wild birds and poultry. (cdc.gov)
Nearly all reported human cases since 2022 were associated with poultry exposures, and no cases of mammal-to-human or human-to-human transmission of HPAI A(H5N1) virus have been identified. (cdc.gov)

On 17 April 2023, the US CDC provided information on the genomic analysis of the samples from the first human infected with avian influenza A(H5N1) in Chile. (poultrymed.com)
New Cases in Scotland Highly pathogenic avian influenza (HPAI) H5N1 was confirmed at a second premises in Lower Barvas, Isle of Lewis on 15 September 2023. (rpra.org)
There is a high risk that Highly Pathogenic Avian Influenza (HPAI H5N1) will arrive in the Southern Ocean during the 2023/24 austral summer. (usap.gov)

Genetic analysis of highly pathogenic avian influenza (H5N1) viruses from poultry and hooded vultures in Burkina Faso shows that these viruses belong to 1 of 3 sublineages initially found in Nigeria and later in other African countries. (cdc.gov)
Only countries where highly pathogenic avian influenza A (H5N1) sequences from avian species are available are named. (cdc.gov)
According to reliable data and information from Gov.co.uk , Birds infected with the most serious strain of bird flu, called highly pathogenic avian influenza (HPAI), usually show some (or all) of the following signs. (oxfordshirewildliferescue.com)
Riverside County Chief Veterinarian Dr. Sara Strongin received confirmation of the Eurasian highly pathogenic avian influenza (or HPAI H5N1) late Tuesday afternoon. (rivco.org)
Genetic range and phylogenetic evaluation of extremely pathogenic avian influenza ( HPAI ) H5N1 viruses circulating in Bangladesh from 2007-2011. (flugenome.org)
Extremely pathogenic avian influenza (HPAI) H5N1 virus has been endemic in Bangladesh since its first isolation in February 2007. (flugenome.org)
In earlier research we examined the function of Canada Geese (Branta canadensis) within the epidemiology of Eurasian extremely pathogenic avian influenza (HPAI) H5N1. (flugenome.org)
Enhanced infectivity of H5N1 extremely pathogenic avian influenza ( HPAI ) virus in pig ex vivo respiratory tract organ cultures following adaptation by in vitro passage. (flugenome.org)
WOAH reported highly pathogenic avian influenza (HPAI) H5N1 in Mai Po Nature Reserve during routine surveillance. (emergence-msd-animal-health.com)
Vaccination of domestic ducks against highly pathogenic avian influenza (HPAI) H5N1 has been done in Asia with mixed results. (usda.gov)
Highly Pathogenic Avian Influenza (HPAI) H5N1 virus is a threat to animal and public health worldwide. (ias.ac.in)
Domestic ducks are key intermediates in the transmission of H5N1 highly pathogenic avian influenza (HPAI) viruses, and therefore are included in vaccination programs to control H5N1 HPAI. (usda.gov)
Highly pathogenic avian influenza (HPAI) A(H5N1) is a strain of the avian influenza virus that primarily affects birds, particularly poultry. (news-medical.net)
Starting in January, the U.S. Department of Agriculture's (USDA) Animal and Plant Health Inspection Service (APHIS) detected highly pathogenic avian influenza (HPAI) A(H5N1) virus in wild birds in the United States followed by multiple detections in U.S. commercial poultry and backyard bird flocks [1,2]. (cdc.gov)
It is referred to as 'highly pathogenic' avian influenza, or HPAI. (bto.org)
Three adult harbor seals in Puget Sound, Washington have tested positive for the Highly Pathogenic Avian Influenza H5N1 strain. (thewhaletrail.org)
Highly pathogenic avian influenza (HPAI) H5N1 has spread across Asia, Europe, and Africa. (greenmatters.com)
Most cases tested in Poland (29 of 47) were positive for highly pathogenic avian influenza (HPAI) A (H5N1) virus. (flu.org.cn)
Gross and microscopic lesions from dog infected with highly pathogenic avian influenza (HPAI) H5N1. (flu.org.cn)
Since its first detection in 1997, highly pathogenic avian influenza (HPAI) H5N1 virus has devastated the poultry industry of numerous countries of the Eastern Hemisphere. (flutrackers.com)
Potential spread of highly pathogenic avian influenza H5N1 by wildfowl: dispersal ranges and rates determined from large-scale satellite telemetry. (britishecologicalsociety.org)
In recent years, wildfowl have been suspected of contributing to the rapid geographic spread of the highly pathogenic avian influenza (HPAI) H5N1 virus. (britishecologicalsociety.org)
The novel Eurasian highly pathogenic avian influenza HPAI A (H5N8) virus spread rapidly and globally during 2014, substantially affecting poultry populations. (cdc.gov)
One particular strain of H5N1, called highly pathogenic avian influenza (HPAI), is responsible for the 'bird flu' scares. (scientificamerican.com)
Since the first occurrence of HPAI H5N1 human cases in Hong Kong in 1997, the public health threat of high pathogenic avian influenza (HPAI) has been a major global issue [ 1 ]. (biomedcentral.com)
To provide guiding principles and minimum requirements for surveillance and diagnosis of H5N1 highly pathogenic avian influenza (HPAI) that can be applied by countries and regional networks. (bvs.br)

Phylogenetic tree for the hemagglutinin (HA) gene of African influenza A (H5N1) strains. (cdc.gov)
The hemagglutinin (HA) sequences of influenza A (H5N1) viruses from Burkina Faso clustered with recent western Asian, Russian, European, and African strains and are clearly distinct from southeastern Asian lineages (data not shown). (cdc.gov)
Phylogenetic comparison of the HA1 genes from Burkina Faso with all African influenza A (H5N1) HA sequences available from GenBank showed that the Burkina Faso strains cluster together and with A/chicken/Ivory Coast/1787/2006 ( Figure 1 ). (cdc.gov)
Nevertheless, there are four strains that have caused concern in recent years: H5N1 (since 1997), H7N9 (since 2013), H5N6 (since 2014), and H5N8 (since 2016). (oxfordshirewildliferescue.com)
Although H5N1, H7N9, and H5N6 strains do not easily spread from human to human, several people have been infected worldwide, resulting in numerous fatalities. (oxfordshirewildliferescue.com)
The info clearly demonstrated the motion of H5N1 strains between Asian nations included on this research on account of migration of untamed birds and/or unlawful motion of poultry throughout borders. (flugenome.org)
HPAI, or high path avian influenza, is fatal and more easily transmissible than low path avian influenza strains that have been common in the U.S. since the early 1900s. (webwire.com)
Canadian scientists who have studied big chunks of the genetic code of the two proteins on the surface of the Manitoba H5N1 viruses have confirmed these viruses are from the family of North American H5N1 viruses, not the strains circulating in Southeast Asia. (recombinomics.com)
We analyzed 226 HA and 92 NA sequences with an emphasis on the H5N1 2.2.1.1 strains in Egypt using a Bayesian discrete phylogeography approach. (biomedcentral.com)
Research describing two mutant strains of H5N1 avian influenza that spread between mammals is likely to be published in its entirety. (scientificamerican.com)
Two teams of scientists, led by Ron Fouchier of Erasmus Medical Center in Rotterdam, the Netherlands, and Yoshihiro Kawaoka of the University of Wisconsin-Madison, have created mutant strains of H5N1 avian influenza. (scientificamerican.com)
Wild H5N1 viruses cannot latch on tothe cells in a person's nose and throat, but the mutant strains created by Fouchier and Kawaoka can spread between ferrets, which are viewed as a good animal model of flu transmission between humans. (scientificamerican.com)

Since 2003, more than 20 countries have reported more than 860 human infections with H5N1 bird flu viruses to WHO. (cdc.gov)
General, the info indicate genetic range amongst circulating viruses and a number of introductions of H5N1 viruses with an elevated threat of human infections in Bangladesh, and institution of H5N1 virus in wild and home fowl populations, which calls for lively surveillance. (flugenome.org)
The dog´s owner stated that the dog had eaten duck carcasses from an area with reported HPAI H5N1 infections in ducks. (flu.org.cn)
Once again, severe neurological symptoms were noted, which have been increasingly linked to HPAI H5 infections (see Cell: The Neuropathogenesis of HPAI H5Nx Viruses in Mammalian Species Including Humans ). (flutrackers.com)
However, the true mortality rate will be lower because there are probably some milder, unrecorded infections of H5N1. (scientificamerican.com)
The increasing number of fatal cases due to H5N1 infections prompted the government of Hong Kong to initiate policies forbidding the slaughtering of live chickens or other poultry in wet markets [ 13 ]. (biomedcentral.com)
To date, HPAI A(H5N1) viruses currently circulating in birds and poultry, with spillover to mammals, and those that have caused human infections do not have the ability to easily bind to receptors that predominate in the human upper respiratory tract. (cdc.gov)

This Asian strain of H5N1 has been transmitted from birds to humans, most of whom had extensive, direct contact with infected birds. (webwire.com)
The Asian strain of H5N1 has not been detected in the U.S. HPAI has been detected three times in the United States: in 1924, 1983 and 2004. (webwire.com)
Kawaoka and his team, whose work has been accepted by Nature, created a chimeric virus with the hemagglutinin protein from H5N1 and the genes from the 2009 pandemic strain of H1N1. (scientificamerican.com)
In 1996, a HPAI strain of H5N1 emerged in South-East Asia and extended throughout several Asian, Middle Eastern, African and European countries. (who.int)

In May of 2005 HPAI H5N1 was found in long range migratory birds at Qinghai Lake. (recombinomics.com)
HPAI H5N1 in migratory birds has been well characterized via full sequences from Qinghai Lake , Novosibirsk , and Mongolia . (recombinomics.com)
Cases of HPAI H5N1 have been confirmed in a number of Canadian provinces and the United States including jurisdictions immediately south of Manitoba in North Dakota and Minnesota along the route for spring migratory birds returning to Manitoba. (gov.mb.ca)
Our results provide a detailed quantitative assessment of the dispersive potential of HPAI H5N1 virus by selected migratory birds. (britishecologicalsociety.org)

There are two types of the virus: high pathogenicity (HPAI) and low pathogenicity (LPAI), which indicate how severe the disease can be if a bird gets infected. (oxfordshirewildliferescue.com)
Thus, finding LPAI in some birds does not preclude HPAI from the same birds or other H5 positive birds. (recombinomics.com)
Because of the size differences between HPAI and LPAI HA and NA genes, the two types of sequences can be easily distinguished one the basis of size. (recombinomics.com)
Instead Canada merely proved that two H5 positive birds contained LPAI H5N1, which doesn't address the presence or absence of H5N1 HPAI in any of the H5 positive birds, including those with LPAI H5N1. (recombinomics.com)
Fully understanding the different awareness, attitudes and protective behaviors adopted by workers in live-poultry markets (LPMWs) and local community residents (CRs) to face the challenges of LPAI and HPAI is very important to minimize viral adaptations to human populations. (biomedcentral.com)

The FDA has approved a vaccine for H5N1 influenza. (medscape.com)
This information should be taken into account when implementing vaccine strategies for control of HPAI in different bird species. (usda.gov)
Because influenza viruses are constantly changing, CDC performs ongoing analyses of HPAI A(H5N1) viruses to identify changes that might allow for spread more easily to and between people, cause serious illness in people, reduce susceptibility to antivirals, affect the sensitivity of diagnostic assays, or reduce neutralization of the virus by vaccine induced antibodies. (cdc.gov)

This variant of the H5N1 virus also illustrates the continuing evolution of the H5N1 virus, and its emergence has caused political controversy. (wikipedia.org)
Phylogeography can highlight the drivers of H5N1 emergence and spread. (biomedcentral.com)
Following the emergence of avian influenza H5N1 and the fear of its pandemic potential, having an adequate preparedness plan became a priority as the World Health Organization (WHO) urged every country to develop and maintain an up-to-date national influenza preparedness plan, and provided guidance on plan content (5). (who.int)
Following the emergence of avian influenza H5N1 to the H1N1 pandemic was a learning experience on and the fear of its pandemic potential, having an adequate which capacity to face future events in the Region can preparedness plan became a priority as the World Health be built and strengthened. (who.int)

In addition to birds and poultry, H5N1 viruses have been detected in some mammals. (sdhumane.org)
To date, few changes in HPAI A(H5N1) viruses of public health concern have been identified and such changes have differed between various HPAI A(H5N1) viruses circulating in wild birds and poultry worldwide or that have sporadically infected humans. (cdc.gov)

H5N1 bird flu viruses first emerged in southern China in 1996. (cdc.gov)

We genetically analyzed influenza A (H5N1) viruses from Burkina Faso poultry and the first gene sequences obtained from African wild birds, hooded vultures ( Necrosyrtes monachus ). (cdc.gov)
The five sequences reported above (only 5 of the 47 H5's were from Manitoba) do little to address the question of HPAI H5 in the positive birds. (recombinomics.com)
Sequencing could then be used to verify that larger HA inserts or smaller NA inserts contained sequences that matched the published sequences for HPAI H5N1. (recombinomics.com)
Phylogenetic analysis of the hemagglutinin (A) and neuraminidase (B) gene sequences of the H5N1 influenza virus isolated from a dog´s lung. (flu.org.cn)

Avian influenza (H5N1) is rare in humans in developed countries. (medscape.com)
Influenza A H5N1 has killed millions of birds and raises serious public health concern because of its potential to spread to humans and cause a global pandemic. (biomedcentral.com)
Avian influenza H5N1 virus is known to cross the species barrier and infect humans and felines. (flu.org.cn)
Sequencing and phylogenetic analysis of the hemaggluttinin (HA) and neuraminadase (NA) genes of the dog´s virus showed that they were similar to those of H5N1 viruses isolated from tigers, chickens, ducks, and humans infected in Thailand during the same time that the dog was infected ( Figure 2A and B ). In addition, analysis of 6 other genes from KU-08 showed similar results (data not shown). (flu.org.cn)
More practically, the research could allow public-health workers to monitor wild viruses for similar mutations that make H5N1 more dangerous to humans. (scientificamerican.com)

HPAI is a "zoonotic disease" that has the potential to spread between animals and people and their pets. (thewhaletrail.org)

This marks the first incidence of HPAI in marine mammals on the West Coast. (thewhaletrail.org)

These results should be taken into account when developing effective vaccination programs for controlling HPAI in different species of ducks, since we demonstrated that not all duck species respond equally to avian influenza vaccination. (usda.gov)
In this study we compared the response to vaccination between two common domestic duck species, Pekin and Muscovy, which were vaccinated using one of three different schedules in order to obtain protection to H5N1 HPAI before one month of age. (usda.gov)
This information is important and should be taken into account when developing effective vaccination programs for controlling HPAI in different species of ducks. (usda.gov)
Monitoring work carried out by the Animal and Plant Health Agency (APHA) also confirmed HPAI in other species including raptors, wildfowl, waders, and gamebirds. (bto.org)
Together, Britain and Ireland support 25% of Europe's breeding seabirds, including more than 50% of the world population of species which have been severely impacted by HPAI, such as Great Skua and Gannet. (bto.org)
We analysed the first large-scale data set of wildfowl movements, including 228 birds from 19 species monitored by satellite telemetry in 2006-2009, over HPAI H5N1 affected regions of Asia, Europe and Africa. (britishecologicalsociety.org)

Avian influenza (HPAI) H5N1 was confirmed in commercial poultry on April 29 at premises near Cantley, Doncaster, according to the Department for Environment, Food & Rural Affairs. (thestar.co.uk)

The widespread detection of H5 raised the possibility of HPAI H5N1 migration into North America from Europe or Asia. (recombinomics.com)
Since most infected animals either recover - or die unnoticed in the wilderness - we don't really have a good handle on how many birds and mammals have been infected, or killed, by HPAI H5Nx avian flu since it arrived in North America nearly two years ago. (flutrackers.com)

Phylogenetic evaluation of the haemagglutinin (HA) gene of HPAI H5N1 viruses demonstrated that 25 Bangladeshi isolates together with two human isolates from 2007-2011 together with some isolates from neighbouring Asian nations (India, Bhutan, Myanmar, Nepal, China and Vietnam) segregate into two distinct clades (2.2 and a couple of.3). (flugenome.org)
Specific H5N1 isolates labeled as Fujian include A/Fujian/1/2005 and A/DK/Fujian/1734/05 (or A/Ck/Fujian/1734/2005). (wikipedia.org)
Like HPAI H5N1 in domestic birds in Asia, all wild bird isolates have a multi-basic HA cleavage site containing the sequence RRRKKR as well as an N1 with a 20 amino acid deletion. (recombinomics.com)
We found that isolates from both animals had the D701N mutation in the polymerase basic 2 gene, previously known to promote adaptation of H5N1 viruses to mammal hosts. (flutrackers.com)

Ducks have been implicated in the dissemination and evolution of H5N1 HPAI viruses. (usda.gov)
Clear differences in response to vaccination were observed, with the Muscovy ducks presenting lower viral antibody titers induced by vaccination and higher number of sick and dead ducks after challenge with a H5N1 HPAI virus. (usda.gov)

Both cats and tigers were reported as becoming infected after eating poultry carcasses harboring HPAI. (greenmatters.com)

Many components contribute to the incidence and transmission of HPAI H5N1 virus, however the function of environmental temperature stays poorly understood. (flugenome.org)

A/Fujian (H5N1) bird flu is notable for its resistance to standard medical countermeasures and its rapid spread. (wikipedia.org)
A/Fujian (H5N1) bird flu is notable for its resistance to standard medical countermeasures, its rapid spread, what it tells us about the continuing evolution of the H5N1 virus, and the political controversy surrounding it. (wikipedia.org)
HPAI A (H5N1) has spread over Europe and the US from October 2021 onward. (news-medical.net)
After the reported spread of HPAI H5N1 virus in Asia, a large, interagency avian influenza virus, or AIV, surveillance effort was implemented throughout the United States during April 2006 to March of 2011. (cdc.gov)
So far, H5N1 has failed to spark a pandemic because it cannot effectively spread between people. (scientificamerican.com)
However, HPAI H5N1 viruses reappeared in 2003, spread across continents, and sickened 826 patients from 2003 to March 31, 2015 [ 5 ]. (biomedcentral.com)

For California Department of Fish and Wildlife HPAI fact sheet, click here . (rivco.org)

In contrast to previous H5N1 viruses, which still circulate to a lesser extent in several countries, at this time, fewer than 10 cases with current H5N1 bird flu viruses have been reported globally. (cdc.gov)

HPAI H5N1 virus was detected in one poultry meat sample. (flu.org.cn)

Since the original human cases of H5N1 originated in Asia [ 1 ], much of the attention concerning the virus has been in Asian countries. (biomedcentral.com)
The pandemic burden became recently more significant in the EMR with the sudden surge in human cases of H5N1 in Egypt. (who.int)
Due significant in the EMR with the sudden surge in human to frequent mutations and reassortment in its genome, cases of H5N1 in Egypt. (who.int)
In a few cases, the source of exposure to HPAI A(H5N1) virus was unknown. (cdc.gov)

This case occurred in a person who had direct exposure to poultry and who was involved in the culling (depopulating) of poultry with presumptive H5N1 bird flu. (cdc.gov)

Till date, the H5N1 virus has claimed 402 human lives, with a mortality rate of 58% and has caused the death or culling of millions of poultry since 2003. (ias.ac.in)

In this study, we have designed three siRNAs (PB2-2235, PB2-479 and NP-865) targeting PB2 and NP genes of avian influenza virus and evaluated their potential, measured by hemagglutination (HA), plaque reduction and Real time RT-PCR assay, in inhibiting H5N1 virus (A/chicken/Navapur/7972/2006) replication in MDCK cells. (ias.ac.in)

The tragic losses we've seen in South America, with well over 20,000 sea lion deaths , are a grim reminder that avian H5N1 continues to spillover into mammals, and that given enough time, it could learn to better adapt to non-avian hosts. (flutrackers.com)

Kawaoka notes that H5N1 viruses already circulate in nature, mutate constantly and could cause pandemics. (scientificamerican.com)

This means there is a high probability of contact with wild birds that may be contaminated with the HPAI virus. (gov.mb.ca)

0.05), indicating that dispersion of H5N1 in Egypt was geographically structured. (biomedcentral.com)

HPAI H5N1 is the type currently affecting parts of Asia and Eastern Europe. (webwire.com)

The flu currently circulating through bird populations up and down Atlantic coastlines is a type of influenza A known as H5N1. (motherjones.com)
For Egypt, future work should focus on using data about vaccination and live bird markets in phylogeography models to study their impact on H5N1 diffusion within the country. (biomedcentral.com)

Pre-exposing Canada Geese (Branta canadensis) to a low-pathogenic H1N1 avian influenza virus protects them in opposition to H5N1 HPAI virus problem. (flugenome.org)

Influenza A(H5N1) viruses from cats possessed two amino acid substitutions in the PB2 protein (526R and 627K) which are two molecular markers of virus adaptation in mammals. (eurosurveillance.org)

Anatomy2

Organisms21

Diseases5

Chemicals and Drugs12

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Psychiatry and Psychology1

Phenomena and Processes4

Disciplines and Occupations1

Technology, Industry, Agriculture3

Information Science2

Health Care3

Geographicals5

Subtype13

Clade8

Outbreak11

Outbreaks16

Infection12

202210

20233

Pathogenic avian influenza26

Strains12

Infections7

Strain4

Migratory birds4

LPAI5

Vaccine3

Emergence4

Birds and poultry2

Viruses first emerged1

Sequences4

Humans5

Zoonotic1

Marine mammals1

Species6

Commercial poultry1

North America2

Isolates4

Ducks2

Carcasses1

Incidence1

Spread6

Wildlife1

Globally1

Poultry meat1

Cases4

Exposure1

Mortality1

Genes1

Spillover1

Circulate1

Wild1

0.051

Asia1

Bird2

H1N11

Mammals1