• At lower, sub-anesthetic doses, ketamine is a promising agent for pain and treatment-resistant depression. (wikipedia.org)
  • Ketamine is especially useful in the prehospital setting, due to its effectiveness and low risk of respiratory depression. (wikipedia.org)
  • Ketamine used to treat severe depression in patients with a history of psychosis does not exacerbate psychosis risk, new research suggests. (medscape.com)
  • As interest in ketamine as a treatment for depression increases, so do concerns about side effects. (medicalnewstoday.com)
  • In March 2019, the Food and Drug Administration (FDA) approved esketamine - a ketamine-based nasal spray - for the treatment of depression . (medicalnewstoday.com)
  • Studies have shown that small doses of ketamine can quickly relieve symptoms of depression. (medicalnewstoday.com)
  • Because there have been very few advances in depression treatment in recent years, ketamine has caused excitement and renewed hope. (medicalnewstoday.com)
  • It is also worth noting that one of the authors, Dr. Carlos A. Zarate, is listed as the co-inventor of a number of ketamine-based therapies for conditions such as depression, anxiety , suicidal ideation, post-traumatic stress disorders, and neuropathic pain. (medicalnewstoday.com)
  • Because ketamine works to relieve depression so swiftly when other drugs have failed, interest in ketamine is likely to continue. (medicalnewstoday.com)
  • Ketamine is an anesthetic that can be used to help treat mental health conditions including major depression and PTSD. (psychologytoday.com)
  • Ketamine is an anesthetic that can be used to help treat a variety of mental health conditions, including treatment-resistant depression /major depression, anxiety , PTSD (post- traumatic stress disorder), OCD ( obsessive-compulsive disorder), bipolar disorder , and certain addictions/substance use disorders. (psychologytoday.com)
  • Ketamine has recently been proposed as a new treatment for depression and post-traumatic stress disorder. (eurekalert.org)
  • Research has found that ketamine may be used to treat depression as well as addiction to alcohol, heroin and cocaine. (dazeddigital.com)
  • You can theoretically get a ketamine nasal spray on prescription on the NHS, but it's quite rare, and you need to be diagnosed with treatment-resistant depression. (dazeddigital.com)
  • A​ recent study published in The New England Journal of Medicine compared the use of ketamine infusions with electroconvulsive therapy (ECT) - two interventions for treatment-resistant major depression. (medicalnewstoday.com)
  • The researchers found that using ketamine may be as effective as electroconvulsive therapy in helping people with treatment-resistant depression, with little to no side effects. (medicalnewstoday.com)
  • The goal of the study was to investigate whether subanesthetic intravenous ketamine was nearly as good as ECT for treatment-resistant depression. (medicalnewstoday.com)
  • Ketamine is good alternative for patients who have been recommended for ECT for treatment of their resistant depression. (medicalnewstoday.com)
  • A large-scale analysis of real-world ketamine intravenous therapy showed promise for treating depression. (psychcentral.com)
  • Ketamine is an FDA-approved anesthetic that's gaining popularity in psychedelic research for its effectiveness in treating depression . (psychcentral.com)
  • Depression is notoriously challenging to treat, and a growing body of evidence suggests that ketamine may help reduce symptoms. (psychcentral.com)
  • Findings suggest that ketamine infusion therapy (KIT) produced "robust, rapid, and durable results" for individuals with depression, according to lead researcher Alison McInnes , MD, Vice President of Medical Affairs at Osmind , a platform designed for treatment resistant mental health practices. (psychcentral.com)
  • While researchers do not yet fully understand how ketamine helps manage depression, Heinzerling said there are some biological explanations, such as how it affects brain chemicals involved in mood, like serotonin , norepinephrine, and the opioid and dopamine systems. (psychcentral.com)
  • Steven L. Mandel, M.D., president and founder of Ketamine Clinics Los Angeles (KCLA), is a world-renowned expert in ketamine treatment for depression, suicidality, PTSD, other mood disorders, and chronic pain conditions. (prnewswire.com)
  • The use of ketamine for depression has grown exponentially in the last 20 years after a team from Yale University School of Medicine discovered that ketamine could rapidly relieve depression symptoms, even treatment-resistant depression. (prnewswire.com)
  • Since then, hundreds of ketamine clinics have opened across the U.S. to provide ketamine therapy for anxiety, depression, and PTSD to patients who want fast-acting, high-quality treatment options. (prnewswire.com)
  • Founded by Steven L. Mandel , M.D., a board-certified anesthesiologist with a master's degree in psychology, and co-founded by Chief Operating Officer and Dr. Mandel's son, Sam Mandel , Ketamine Clinics Los Angeles specializes in the administration of IV ketamine to dramatically improve the quality of life for patients battling depression, suicidality, PTSD, other mood disorders, and chronic pain. (prnewswire.com)
  • Achieving an 83 percent success rate for depression and mood disorder patients, and a 70 percent success rate for pain patients, Ketamine Clinics Los Angeles is blazing the trail for a faster, safer, and more effective solution to mental health disorders and chronic pain conditions. (prnewswire.com)
  • Prescriptions for ketamine have soared in recent years, driven by for-profit clinics and telehealth services offering the medication as a treatment for pain, depression, anxiety and other conditions. (ktar.com)
  • Ketamine targets a brain chemical messenger called glutamate, which is thought to play a role in both pain and depression. (ktar.com)
  • We want patients to disassociate or feel separate from their pain, depression or anxiety," said Dr. David Mahjoubi, owner of Ketamine Healing Clinic in Los Angeles. (ktar.com)
  • 3 The present article examines issues related to dosing, rate of administration, route of administration, duration of treatment, and frequency of sessions when ketamine is used in subanesthetic doses for the treatment of depression, especially treatment-resistant depression. (psychiatrist.com)
  • 4 The first 2 randomized controlled trials (RCTs) of subanesthetic ketamine dosing for depression employed a 0.5 mg/kg IV dose. (psychiatrist.com)
  • Adverse effects of ketamine include increased blood pressure, elevated heart rate, respiratory depression, vocalization, erratic and prolonged recovery, spastic jerking movements and muscle tremors. (petplace.com)
  • The effect was far smaller than in an earlier ketamine trial as my crudely-mashed-up graph shows (although note that the patient populations were somewhat different, one bipolar and one unipolar depression, although their baseline severity was the same. (discovermagazine.com)
  • National Institutes of Health researchers found that a single, low-dose ketamine infusion was relatively free of side effects for patients with treatment-resistant depression. (nih.gov)
  • However, widespread off-label use of intravenous subanesthetic-dose ketamine for treatment-resistant depression has raised concerns about side effects, especially given its history as a drug of abuse. (nih.gov)
  • Meanwhile, the U.S. Food and Drug Administration earlier this year approved an intranasal form of ketamine called esketamine, which can be administered to adults with treatment-resistant depression in a certified doctor's office or clinic. (nih.gov)
  • Comprehensive assessment of side effects associated with a single dose of ketamine in treatment-resistant depression. (nih.gov)
  • The anesthetic ketamine has drawn excitement in recent years as a fast-acting and effective treatment for severe depression. (livescience.com)
  • Now, a small, new study sheds light on exactly how the drug works to treat depression, with a surprising finding: Ketamine needs to activate opioid receptors in order to have antidepressant effects. (livescience.com)
  • In light of the current opioid epidemic , the findings also underscore the need for caution against the widespread and repeated use of ketamine for depression until more research is done on the drug's mechanism of action and its risk of abuse among patients, the researchers said. (livescience.com)
  • In recent years, studies have found that ketamine can have fast and dramatic effects for people with depression , improving symptoms within just hours, rather than the weeks that many other antidepressants take. (livescience.com)
  • Exactly how ketamine works to treat depression isn't known. (livescience.com)
  • In the new study, the researchers hypothesized that ketamine works to treat depression at least in part by activating opioid receptors. (livescience.com)
  • The study found that when participants received ketamine with the placebo, they experienced a dramatic reduction in their symptoms of depression , but when they received naltrexone, the ketamine had almost no effect on their symptoms of depression. (livescience.com)
  • He also urged caution about the use of ketamine for depression. (livescience.com)
  • By providing detailed information on conditions such as depression, PTSD, chronic pain, and fibromyalgia, the clinic helps patients understand the potential benefits of ketamine therapy for their specific circumstances. (digitaljournal.com)
  • For those seeking advanced and successful treatments for conditions such as depression, PTSD, chronic pain, fibromyalgia, ADHD, and addiction, Keystone Advanced Ketamine Therapy is the ultimate destination. (digitaljournal.com)
  • On the business side of the ketamine story, the former Naurex team that sold its NMDA depression drug candidate to Allergan last year scored $65 million in venture funding . (medpagetoday.com)
  • Australian researchers have completed the world's first randomised control trial (RCT) assessing the efficacy and safety of ketamine as a treatment for depression in elderly patients. (scienceblog.com)
  • Led by a team of researchers from UNSW Sydney and Black Dog Institute, the trial tested different doses of ketamine amongst 16 older age participants (aged over 60 years) who had treatment-resistant depression, administered at Wesley Hospital. (scienceblog.com)
  • Previous studies into ketamine treatments for older people with depression - which are limited to just five case reports - show mixed success, with findings limited by small sample sizes. (scienceblog.com)
  • People who got intravenous ketamine at three private ketamine infusion clinics had "significant improvement" in symptoms of depression, anxiety and suicidal ideation, a new study says. (cnn.com)
  • The researchers looked at data on 424 people with treatment-resistant depression who were treated between November 2017 and May 2021 at three ketamine infusion clinics in Virginia that specialize in people with suicidal ideation, depression or anxiety. (cnn.com)
  • Ketamine, a widely used anesthetic agent, is currently being investigated as a novel therapeutic for depression and suicidality. (nih.gov)
  • In this article, we review current evidence supporting the rapid effects of ketamine on suicidal ideation in the context of unipolar and bipolar depression. (nih.gov)
  • Researchers at the National Institute of Health say that a single dose of Ketamine eliminates depressive symptoms within minutes of administration for people with bipolar depression. (choosehelp.com)
  • The findings reported in Arline Kaplan's article on ketamine ( New Claims and Findings for Ketamine in Severe Depression ), are certainly exciting, particularly for those of us who have attended the considerable suffering of many patients with treatment-resistant depression (TRD). (psychiatrictimes.com)
  • The UK's Medicines & Healthcare Products Regulatory Agency is refusing to respond to the concerns of psychiatrists, parliamentarians, patients and other experts about the impending licensing of the street drug ketamine as a treatment for depression. (madinamerica.com)
  • From The Independent: 'Ketamine-based treatments for severe depression could further fuel the addiction epidemic sweeping the US, researchers have warned, after a new study found the. (madinamerica.com)
  • Researchers report that dangerous side effects are not being adequately reported in the trials of ketamine for depression. (madinamerica.com)
  • From TIME: The club drug ketamine has been found in some small studies to help treat people categorized as having treatment-resistant depression. (madinamerica.com)
  • The Daily Telegraph reports on a warning published in the Medical Journal of Australia that urges doctors not to "jump the gun in prescribing patients the drug ketamine to treat depression. (madinamerica.com)
  • Ryan Oakley, MD, takes a closer look at the recent history of ketamine in depression. (hcplive.com)
  • So then, a group decided to see if we could intervene directly on the glutamate system with an NMDA antagonist, like ketamine, to see what kind of effect would that have on depression. (hcplive.com)
  • The FDA recently put out a warning on compounded ketamine, because ketamine is getting marketed almost like a snake oil treatment for all the different types of mental illness where there's not a lot of evidence to support it (except for in depression, IV formulation, and a specific way of delivery). (hcplive.com)
  • We have previously shown that a single dose of ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist, is associated with a rapid reduction in depressive symptom severity and SI in patients with treatment-resistant depression. (nih.gov)
  • Physicians and patients are excited about ketamine, the latest drug to treat depression, but Stanford psychiatrist Alan Schatzberg says we need to tread carefully. (stanford.edu)
  • After a number of positive reports in the medical literature about its effects on depression, ketamine became more widely used in existing pain clinics, and new ketamine clinics started popping up around the country. (stanford.edu)
  • Patients eager to lift the fog of depression often pay thousands of dollars - insurance rarely pays for the treatment - to lie in a chair while ketamine infuses into their veins. (stanford.edu)
  • The first report to show its effect on depression was in 2000, when a Yale study indicated that in seven study participants, ketamine was reported to have an effect on mood. (stanford.edu)
  • Then, in 2006, a study from the National Institute of Mental Health showed that ketamine reduced depression more rapidly than placebo. (stanford.edu)
  • Intravenous ketamine has garnered much attention because small doses produce rapid relief - in as little as four hours - in some patients who suffer from treatment-resistant depression. (stanford.edu)
  • Ketamine clinics, in which patients receive the drug intravenously, have been around for several years to treat chronic pain and depression. (stanford.edu)
  • Ketamine is showing promise as a treatment for depression. (latitudes.org)
  • NMDA glutamatergic receptors are potential targets for novel therapies for the treatment of depression, with ketamine, an antagonist of such receptors, as one of these therapies. (bvsalud.org)
  • Considering that there is a trend toward an increased clinical use of ketamine as an antidepressant and there is little information on the safety and efficacy of its prolonged use and in perinatal period, this review aims to provide more recent information on the effects of depression on progeny development and the general use of ketamine as a treatment for postpartum depression. (bvsalud.org)
  • For that, a bibliographic survey was conducted in guidelines and journals obtained from the SciELO, PubMed and ScienceDirect databases between the years 2000 and 2017, using the following terms as inclusion criteria: depression, postpartum depression, ketamine, antidepressant and escetamine. (bvsalud.org)
  • Ketamine has promising potential for the treatment of depressive disorders in general, including postpartum depression, minimizing the risks to offspring development. (bvsalud.org)
  • Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. (wikipedia.org)
  • Ketamine is a novel compound that was derived from phencyclidine in 1962, in pursuit of a safer anesthetic with fewer hallucinogenic effects. (wikipedia.org)
  • At anesthetic doses, ketamine induces a state of "dissociative anesthesia", a trance-like state providing pain relief, sedation, and amnesia. (wikipedia.org)
  • When used at anesthetic doses, ketamine usually stimulates rather than depresses the circulatory system. (wikipedia.org)
  • Ketamine is an option in children, as the sole anesthetic for minor procedures or as an induction agent followed by neuromuscular blocker and tracheal intubation In particular, children with cyanotic heart disease and neuromuscular disorders are good candidates for ketamine anesthesia. (wikipedia.org)
  • Usually, people are given a 'sub-anesthetic dose' of ketamine in formal treatment, but this isn't the same thing as a microdose. (dazeddigital.com)
  • Ketamine, most commonly used as a horse tranquilizer, is a general anesthetic, and xanax induces drowsiness. (businessinsider.com)
  • Ketamine was approved more than 50 years ago as a powerful anesthetic for patients undergoing surgery. (ktar.com)
  • In other species, ketamine is used to sedate before anesthesia and as part of an injectable anesthetic protocol. (petplace.com)
  • Ketamine has been used for decades as an anesthetic in hospitals, but it has also developed a reputation as an illegal "club drug," known as "Special K. (livescience.com)
  • Ketamine is a powerful medication used in hospitals primarily as an anesthetic. (cnn.com)
  • Ketamine is a fast-acting anesthetic and painkiller used primarily in veterinary surgery. (google.com)
  • First, to understand where ketamine is right now what it's been used for, its primary use is the procedural anesthetic and medicine. (hcplive.com)
  • Its use goes back many years, as physicians started to notice that soldiers treated with ketamine as a battlefield anesthetic more frequently escaped PTSD off the battlefield. (veteranstoday.com)
  • Ketamine was first created in 1962 and has been used as a surgical anesthetic since 1970. (stanford.edu)
  • Ketamine HCl (C 13 H 16 ClNO.HCl, MW 274.2) is used as an anesthetic, as well as an analgesic. (uspharmacist.com)
  • I already found Ketamine in Hale's Medications and Mothers' Milk (2021), however, it mentioned Ketamine as a general anesthetic agent only. (infantrisk.com)
  • I'm referring to the use of the agent ketamine , which has been used as an anesthetic previously for children with pediatric conditions and also for burn victims. (medscape.com)
  • The reason for this is that ketamine-which has been repurposed to extend its uses beyond its traditional anesthetic and pain-relieving purposes to neuropsychiatric disorders-is a pharmacologic cousin to phencyclidine or PCP . (medscape.com)
  • Ketamine has been used safely for anesthetic purposes and is now being applied for treatment of refractory neuropsychiatric conditions, all of which is good, But because of the dramatic results in a very dire population (people with treatment-refractory mental disorders), the use of ketamine has really expanded before the research can define or answer all of the questions related to incorporating a new treatment agent into standard practice. (medscape.com)
  • But bare in mind that ketamine, which is approved by the US Food and Drug Administration for anesthetic purposes, is not available orally. (medscape.com)
  • To better understand how the imaging data might be related to high-resolution electrophysiological measurements, we have here analyzed the aperiodic part of the local field potential (LFP) in rodents treated with a classic psychedelic (LSD) or a dissociative anesthetic (ketamine). (lu.se)
  • This is the largest real-world study of intravenous ketamine therapy outcomes ever performed, and it also represents more patients surveyed than ever studied in academic trials to date," McInnes told Psych Central. (psychcentral.com)
  • Is intravenous ketamine therapy safe? (psychcentral.com)
  • Heinzerling explained that intravenous ketamine is typically dosed based on an individual's weight: 0.5 milligrams per kilogram as a starting dose, infused over 40 to 60 minutes. (psychcentral.com)
  • A new study, published this month in the Journal of Affective Disorders, investigated the effectiveness of weekly intravenous ketamine injections as a treatment for. (madinamerica.com)
  • A pivotal new study published in January 2022 analyzed the effectiveness of ketamine therapy in real-world community care settings - the largest analysis of its kind. (psychcentral.com)
  • LOS ANGELES - Oct. 27, 2022 - PRLog -- Ketamine, a Schedule III controlled substance, has a variety of uses. (prlog.org)
  • Ketamine is an NMDA receptor pore blocker and that accounts for most of its actions, except the antidepressant effect, the mechanism of which is a matter of much research and debate. (wikipedia.org)
  • While the latter binds to 5-HT2A receptors in the brain, ketamine binds to NMDA receptors, but both work to create new neurons and neural connections. (dazeddigital.com)
  • AZD6765 works much like ketamine in that it blocks brain NMDA receptors. (discovermagazine.com)
  • This is what we'd see if NMDA blockers do have a modest antidepressant effect but the dramatic improvements seen on ketamine are largely active placebo phenomena. (discovermagazine.com)
  • Then again, it's also consistent with ketamine being a powerful antidepressant and AZD6765 just being less effective because it's a milder blocker of NMDA - effectively, a low dose of ketamine. (discovermagazine.com)
  • In a recent study published in the journal Scientific Reports , a group of researchers investigated the influence of ketamine, a N-Methyl-D-Aspartate (NMDA) receptor antagonist, on mentalizing deficits and associated neural responses, providing insights into glutamate's role in schizophrenia's social cognition impairments. (news-medical.net)
  • The role of glutamatergic NMDA receptors in these deficits is undetermined despite ketamine studies indicating potential links. (news-medical.net)
  • Studies utilizing NMDA-receptor antagonists like ketamine, known for creating narcotic and psychotomimetic effects, aim to understand schizophrenia-related glutamate signaling deficiencies. (news-medical.net)
  • Here's a recent review article on Ketamine (and other anti NMDA receptor antagonists). (latitudes.org)
  • PCP acts as an NMDA receptor antagonist, as does ketamine, but perhaps more potent. (medscape.com)
  • Ketamine infusions are used for acute pain treatment in emergency departments and in the perioperative period in individuals with refractory pain. (wikipedia.org)
  • In multiple clinical trials, ketamine infusions delivered short-term pain relief in neuropathic pain diagnoses, pain after traumatic spine injury, fibromyalgia, and complex regional pain syndrome (CRPS). (wikipedia.org)
  • One group had 195 participants and received ketamine intravenous infusions twice weekly for three weeks. (medicalnewstoday.com)
  • His doctors prescribed four- to six-hour IV infusions of ketamine for pain related to a rare bone and joint disorder. (ktar.com)
  • Still, he credits ketamine with reducing his pain during the year that he received twice-a-month infusions. (ktar.com)
  • Patients can pay extra for ketamine nasal sprays and tablets to use between infusions. (ktar.com)
  • However, this research has not included patients with past or current psychosis, based on the assumption that psychosis will increase with ketamine administration, since side effects of ketamine can include transient "schizophrenia-like" psychotomimetic phenomena including perceptual disorders and hallucinations in healthy individuals, the investigators note. (medscape.com)
  • Although some papers have collated the side effects of ketamine, often, these did not include a placebo . (medicalnewstoday.com)
  • Researchers have identified two brain phenomena that may explain some of the side-effects of ketamine. (eurekalert.org)
  • Our purpose wasn't really to look at the effects of ketamine, but to use it as a tool to probe the brain activity in sheep with and without the Huntington's disease gene," said Morton. (eurekalert.org)
  • After intramuscular injection, the effects of ketamine are seen within 10 minutes. (petplace.com)
  • In the present study, researchers delved into the effects of ketamine on symptoms of schizophrenia and mentalizing, the ability to understand others' mental states. (news-medical.net)
  • We can demonstrate an opioid effect in humans because naltrexone, which blocks the effects of opioids, also blocks the antidepressant effects of ketamine. (stanford.edu)
  • Dr. Padma Gulur, a Duke University pain specialist, stands for a portrait on Friday, Oct. 27, 2023, in Durham, N.C. Prescriptions for ketamine have soared in recent years as doctors adopt the mind-altering drug as an alternative pain treatment. (ktar.com)
  • 3 Ketamine could also rapidly reduce suicidal ideation in a way that is at least partially independent from its effect on mood. (bmj.com)
  • More than 70% of people with suicidal ideation benefited from ketamine therapy. (psychcentral.com)
  • The primary aim of this study was to comprehensively report [side effects] associated with ketamine by reviewing 120 symptoms associated with a single intravenous infusion of subanesthetic-dose ketamine. (medicalnewstoday.com)
  • Six of the sheep were given a single higher dose of ketamine, 24mg/kg. (eurekalert.org)
  • After the high dose of ketamine the brains of these sheep completely stopped. (eurekalert.org)
  • Ketamine can also be administered intramuscularly, producing a psychedelic effect at the immediate onset, compared to an equivalent dose given slowly by IV over an hour. (psychcentral.com)
  • Ketamine is commonly administered intravenously in the dose of 0.5 mg/kg. (psychiatrist.com)
  • Ketamine may be administered as rapidly as in a bolus dose to as slowly as across 100 minutes. (psychiatrist.com)
  • Ketamine is most commonly administered in the dose of 0.5 mg/kg, but some patients may respond to doses as low as 0.1 mg/kg, and others may require up to 0.75 mg/kg. (psychiatrist.com)
  • There is likely to be a complex interaction between ketamine dose, session duration, route of administration, frequency of administration, and related practice. (psychiatrist.com)
  • Studies have shown that a single, subanesthetic-dose (a lower dose than would cause anesthesia) ketamine infusion can often rapidly relieve depressive symptoms within hours in people who have not responded to conventional antidepressants, which typically take weeks or months to work. (nih.gov)
  • Participants received increasing doses of ketamine over a period of five weeks, with doses optimised for each individual participant using a new dose-titration approach developed by Professor Loo's Sydney research team and collaborators. (scienceblog.com)
  • It is encouraging, however, that such an active-control study is under way at New York State Psychiatric Institute, in which depressed participants are randomly assigned to receive a single intravenous dose of either ketamine or midazolam (a short-acting benzodiazepine with pronounced amnestic effects). (psychiatrictimes.com)
  • The main aim of the study is to verify the efficacy and safety of a single dose of psilocybin 20 mg in the treatment of TRD in adults in a randomized clinical trial with active comparator ketamine 200 mg (rapid onset acting antidepressant) and negative control midazolam 5 mg (drug with no antidepressant properties). (centerwatch.com)
  • Because ketamine is given as a single parenteral dose for anesthesia, the dosing parameters for psychiatric illness, which presumably require ongoing or maintenance treatment after acute treatment, haven't been fully worked out. (medscape.com)
  • Although rare, ketamine may induce brief or recurrent laryngospasm even at a therapeutic dose. (msdmanuals.com)
  • Animals in Group 1 (n = 4) received a mean xylazine - ketamine dose of 2.77 +/- 0.99 mg/kg xylazine plus 3.32 +/- 0.19 mg/kg ketamine in males and 2.39 +/- 0.10 mg/kg xylazine plus 4.29 +/- 0.17 mg/kg ketamine in females . (bvsalud.org)
  • Animals in Group 2 (n = 25) received a mean xylazine - ketamine dose of 1.70 +/- 0.41 mg/kg xylazine plus 3.06 +/- 0.74 mg/kg ketamine in males and 1.82 +/- 0.29 mg/kg xylazine plus 3.29 +/- 0.52 mg/kg ketamine in females . (bvsalud.org)
  • The distinguishing features of ketamine anesthesia are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure, and moderate bronchodilation. (wikipedia.org)
  • The use of ketamine in anesthesia reflects its characteristics. (wikipedia.org)
  • Protective airway reflexes are preserved and it is sometimes possible to administer ketamine anesthesia without protective measures to the airways. (wikipedia.org)
  • Due to the bronchodilating properties of ketamine, it can be used for anesthesia in people with asthma, chronic obstructive airway disease, and with severe reactive airway disease including active bronchospasm. (wikipedia.org)
  • For dogs and cats, Ketamine is often used for restraint, sedation , pain and/or anesthesia . (petplace.com)
  • In cats, ketamine is used for restraint as well as anesthesia. (petplace.com)
  • Since ketamine does not offer good muscle relaxation, it should not be used as the sole agent for anesthesia. (petplace.com)
  • In cats, ketamine is also used for anesthesia in combination with other drugs and is dosed at 10 to 15 mg per pound (22 to 33 mg/kg) intramuscular or 1 to 2 mg per pound (2 to 4 mg/kg) intravenous. (petplace.com)
  • Dosing, frequency, and types of administration (ketamine IV, esketamine IV, or esketamine subcutaneous) varied from study to study. (medscape.com)
  • He also explores the differences between ketamine and esketamine. (hcplive.com)
  • We're also going to talk about the evolution and the creation of the FDA-approved insurance-covered form of ketamine, which is esketamine, and how we use that in our clinics as an intervention. (hcplive.com)
  • So, breaking down the difference between ketamine and esketamine, the biggest one is which one's actually insurance-based, which one has approval. (hcplive.com)
  • However, insurance covering esketamine actually makes it more affordable for patients, whereas ketamine treatments, you're not just paying for the medication, you're paying for staff, you're paying for monitoring, paying for IV, all these things. (hcplive.com)
  • So, we don't have a place where we can find out more about the side effects of how safe ketamine actually is, whereas esketamine does have that. (hcplive.com)
  • Recently, the FDA approved esketamine, a molecule that is a mirror image of ketamine, as a nasal spray. (stanford.edu)
  • He spoke recently with science writer Mandy Erickson about the dangers and unknowns of ketamine and esketamine. (stanford.edu)
  • Ketamine Lead Gen is a boutique Marketing Agency servicing KetamineTreatment Clinics and Wellness Clinics that are looking to attract new patients for treatments including Ketamine IV, Intramuscular Ketamine, Sublingual Ketamine, Esketamine (Spravato) Treatment, TMS Therapy, SGB Treatment, NAD Infusion Therapy, Nutritional IV, and more. (prlog.org)
  • Liver and urinary toxicity have been reported among regular users of high doses of ketamine for recreational purposes. (wikipedia.org)
  • Different doses of ketamine were given to 12 sheep and their brain activity recorded with EEG. (eurekalert.org)
  • Following the RCT, participants also received 12 ketamine treatments in an open-label phase to investigate the effectiveness of multiple doses of ketamine. (scienceblog.com)
  • Through my research, I found that ketamine therapy in connection with psychotherapy provided patients with a safe psychedelic experience under the care of a trained practitioner. (psychologytoday.com)
  • A​ new study found that ketamine infusion is comparable to electroconvulsive therapy in treating major depressive disorder. (medicalnewstoday.com)
  • 530 women underwent obstetric or gynecological operative procedures supported by non- anesthetist clinicians using the ESM- Ketamine package between November 1, 2013 and September 30, 2017. (bvsalud.org)
  • A meta-analysis of nine studies, encompassing 41 patients with TRD and a history of psychosis, suggests ketamine is safe and effective and did not exacerbate psychotic symptoms in this patient population. (medscape.com)
  • We believe our findings could encourage clinicians and researchers to examine a broadened indication for ketamine treatment in individual patients with high levels of treatment resistance, carefully monitoring both clinical response and side effects, specifically looking at possible increases in psychotic symptoms," study investigator Jolien K. E. Veraart, MD, University of Groningen, University Medical Center Groningen, the Netherlands, told Medscape Medical News . (medscape.com)
  • They also note anti-anhedonic effects of subanesthetic ketamine doses have been reported, without adversely impacting long-term psychotic symptoms in patients with schizophrenia. (medscape.com)
  • To investigate, the researchers conducted a literature search and selected 9 articles (N = 41 patients) that reported on ketamine treatment in patients with a history of psychosis or current psychotic symptoms. (medscape.com)
  • In seven studies, ketamine was found to improve depressive symptoms and in two studies, improvement in psychotic symptoms was also shown. (medscape.com)
  • Ketamine showed good antidepressant effects and, in some cases, the comorbid symptoms even improved or disappeared after ketamine treatment," Veraart summarized. (medscape.com)
  • Overall, of the 120 symptoms, the researchers could significantly associate 33 with ketamine treatment. (medicalnewstoday.com)
  • 'Ketamine Bladder' has symptoms similar to cystitis or a UTI. (dazeddigital.com)
  • Through gaining the trust of its clients, Keystone Advanced Ketamine Therapy has received outstanding testimonials highlighting significant improvements in symptoms. (digitaljournal.com)
  • The study's participants, who were administered ketamine, exhibited significantly more schizophrenia-related symptoms than the control group across various factors, except for hostility symptoms. (news-medical.net)
  • There have been recent reports about how Ketamine, also known as "Special K", has surprisingly quick and positive effects on the symptoms of bipolar disorder. (choosehelp.com)
  • What PTSD Symptoms Can Ketamine Help With? (veteranstoday.com)
  • Ketamine therapy, therefore, can help with these symptoms. (veteranstoday.com)
  • the reason we are considering ketamine are ds's symptoms. (latitudes.org)
  • Some patients may develop withdrawal symptoms from ketamine such as anxiety, sweating, and palpitations. (msdmanuals.com)
  • Lower urinary tract symptoms such as dysuria, urinary frequency, and hematuria have been reported among long-term ketamine users. (msdmanuals.com)
  • Offering comprehensive care for a variety of conditions, Keystone Advanced Ketamine Therapy is a one-stop solution for patients seeking exceptional treatment outcomes. (digitaljournal.com)
  • Keystone Advanced Ketamine Therapy has completely transformed my life," said one ecstatic patient. (digitaljournal.com)
  • Contact Keystone Advanced Ketamine Therapy today to schedule a consultation and embark on a journey towards a happier and healthier life. (digitaljournal.com)
  • Positive results from carefully monitored trials with ketamine treatment in these patients have motivated us to summarize the currently available knowledge to inform our colleagues," she said. (medscape.com)
  • Nevertheless, this study is another step along the path to a full understanding of the impact of ketamine treatment. (medicalnewstoday.com)
  • For optimal healing, a ketamine treatment program should be used in connection with psychotherapy. (psychologytoday.com)
  • In preparing to provide ketamine therapy, I am addressing the frequently asked questions about the benefits, use in mental health, and treatment plans available. (psychologytoday.com)
  • What can patients expect from a ketamine treatment session? (psychologytoday.com)
  • While microdosing ketamine is much less common than microdosing shrooms , for example, ketamine treatment is becoming more common in clinical settings, so it's no surprise that some people are beginning to self-medicate with the drug. (dazeddigital.com)
  • Overall, the ketamine intervention group had fewer problems with memory recall after the three weeks of treatment. (medicalnewstoday.com)
  • The finding that six sessions of ketamine was no less effective than nine sessions of ECT and produced milder side effects than ECT, has enormous implications for guiding which treatment should be recommended when patients fail to improve with first-line treatments. (medicalnewstoday.com)
  • As one of the first and most prestigious ketamine treatment centers in the United States , Ketamine Clinics Los Angeles has a history of establishing best practices for the entire ketamine therapy community. (prnewswire.com)
  • As the only clinic of its class to specialize exclusively in this modern therapy, Ketamine Clinics Los Angeles offers each patient a custom-tailored treatment plan in a private, serene environment, designed for optimal, long-lasting results. (prnewswire.com)
  • Ketamine also didn't result in lower rates of opioid prescribing in the months following treatment, a common goal of therapy, according to Gulur. (ktar.com)
  • This article presents a qualitative review and summary about what is known about ketamine dosing, rate of administration, route of administration, duration of treatment, and frequency of sessions. (psychiatrist.com)
  • To examine this possibility, the researchers gave participants the opioid-blocking drug naltrexone before they underwent ketamine treatment. (livescience.com)
  • Neither the participants nor the researchers knew whether the patients had received naltrexone or the placebo prior to their ketamine treatment. (livescience.com)
  • The results were so clear that the researchers stopped the study early to avoid exposing more people to "a clearly ineffective and noxious combination treatment," the researchers said, referring to the ketamine-plus-naltrexone treatment. (livescience.com)
  • Not only was ketamine well-tolerated by participants, with none experiencing severe or problematic side effects, but giving the treatment by a simple subcutaneous injection (a small injection under the skin) was also shown to be an acceptable method for administering the drug in a safe and effective way. (scienceblog.com)
  • As part of the double-blind, placebo-controlled trial, an active control treatment which causes sedation similar to ketamine, was used to substitute for one of the treatment sessions. (scienceblog.com)
  • Repeated treatments also resulted in a higher likelihood of remission or a longer time to relapse, with an overall response and remission rate of 68.8 percent for the patients receiving ketamine treatment. (scienceblog.com)
  • We then discuss several future directions that are necessary before ketamine can be considered a viable treatment option for suicidality in clinical settings. (nih.gov)
  • If the early and encouraging ketamine findings are borne out in large, randomized, double-blind, controlled studies, this will represent a significant advance in our treatment options for MDD. (psychiatrictimes.com)
  • 5 Surely, a patient with severe, treatment-resistant MDD should be apprised of ECT as an alternative to a ketamine trial, if consent is to be fully "informed. (psychiatrictimes.com)
  • Ketamine treatment, which was being hailed as a 'miracle cure', backfired so spectacularly that it very nearly cost me my life. (madinamerica.com)
  • Researchers Find Inadequate Reporting of the Dangers of Ketamine Treatment for. (madinamerica.com)
  • So, what's special about ketamine, why is this being developed as an interventional treatment? (hcplive.com)
  • Ketamine is not approved by the FDA for any kind of mental health treatment at this point. (hcplive.com)
  • Ketamine is a fairly new treatment for PTSD, but it's rapidly become more and more common even in the few years that it's been in the cultural zeitgeist. (veteranstoday.com)
  • If you're looking for a treatment option for PTSD, especially if you've been told that your PTSD is treatment-resistant, ketamine may be a good option. (veteranstoday.com)
  • Here's what you need to know about ketamine treatment for PTSD. (veteranstoday.com)
  • How Does Ketamine Treatment Work for PTSD? (veteranstoday.com)
  • Who Should I Talk to So I Can Start Ketamine Treatment? (veteranstoday.com)
  • After this, you might want to look into clinics that offer ketamine treatment at home. (veteranstoday.com)
  • Some examples of such channels include Google Ads, various PR efforts, and partnerships with organizations that are relevant to what treatment you are providing, whether it be Ketamine Infusion, Sublingual Ketamine, or Intramuscular Ketamine. (prlog.org)
  • Why in the world would you give Ketamine as a treatment? (latitudes.org)
  • My question is what could help ds and he meets no only criteria for PANS but also for bi-polar disorder as they are defined by the physician (Papolos) who started ketamine treatment for children. (latitudes.org)
  • During this time options for treatment were physical restraint only until November 2014 at which time intramuscular haloperidol and benzodiazepine (lorazepam or midazolam) were added and then in 2016 intramuscular ketamine was added. (ems1.com)
  • Innovative psychiatrists are responding to the pleas of patients to make treatment with ketamine available in one form or another. (medscape.com)
  • LOS ANGELES , Nov. 25, 2019 /PRNewswire/ -- Ketamine Clinics Los Angeles, the country's leading provider of ketamine infusion therapy, will be featured on the Emmy® Award-winning daytime talk show The Doctors this coming Monday, November 25 th, 2019 at 3 p.m. (prnewswire.com)
  • A petition asking for justice for Elijah McClain has garnered over 2 million signatures, after the 23-year-old Black man was injected with ketamine by first responders in August 2019 and died a few days later. (newsweek.com)
  • Off-label ketamine treatments are available at community clinics and administered by psychiatrists. (psychcentral.com)
  • Under the expert guidance of Dr. Depue, a renowned specialist in ketamine therapy, the clinic provides cutting-edge treatments in a friendly and professional atmosphere. (digitaljournal.com)
  • Dr. Depue's commitment to providing innovative treatments is evident through Keystone Advanced Ketamine Therapy's holistic approach. (digitaljournal.com)
  • One of the compelling features of ketamine is the rapidity of its antidepressant effects, which peak just 24 h after infusion, setting it apart from other existing treatments. (nih.gov)
  • It is important to target your market when advertising ketamine treatments. (prlog.org)
  • Try conducting some research in order to identify potential patients that could use ketamine treatments. (prlog.org)
  • The content we create - whether it be on your website, social media platforms, or other materials - is always engaging and informative so that people can learn more about what you have to offer in terms of ketamine treatments. (prlog.org)
  • This success has shown the potential benefits of ketamine therapy in a variety of individuals. (veteranstoday.com)
  • In this episode of The Doctors , Dr. Mandel educates viewers on how to choose a reputable ketamine clinic where they can connect with a first-class care team that puts patients first, something the care team at Ketamine Clinics Los Angeles is known for. (prnewswire.com)
  • Ketamine Clinics Los Angeles is the country's leading provider of IV ketamine infusion therapy. (prnewswire.com)
  • As the first and only ketamine clinic accredited by The American Association for Accreditation of Ambulatory Surgery Facilities (AAAASF), Ketamine Clinics Los Angeles is the leader in patient safety and comfort. (prnewswire.com)
  • Fass environmental information for Ketalar (ketamine) from Pfizer (dowloaded 2021-12-08). (janusinfo.se)
  • However, as with many antidepressants, the results of a single administration of ketamine wane with time. (wikipedia.org)
  • There's a lot of interest in the idea that ketamine provides unparalleled rapid, powerful antidepressant effects, even in people who haven't responded to conventional antidepressants. (discovermagazine.com)
  • In cats, ketamine is dosed at 3 to 5 mg per pound (6 to 11 mg/kg) intramuscular for restraint and mild sedation. (petplace.com)
  • Outcomes of prehospital chemical sedation with ketamine versus haloperidol and benzodiazepine or physical restraint only. (ems1.com)
  • Benzodiazepines with or without antipsychotic agents were the staple of prehospital chemical sedation until ketamine began to emerge in emergency medicine and prehospital literature [2,3]. (ems1.com)
  • In a study aimed at understanding the effect of therapeutic drugs on the brains of people living with Huntington's disease, researchers used electroencephalography (EEG) to measure immediate changes in the animals' brain waves once ketamine - an anaesthetic and pain relief drug - was administered. (eurekalert.org)
  • The researchers think that this pause in brain activity may correspond to what ketamine abusers describe as the 'K-hole' - a state of oblivion likened to a near-death experience, which is followed by a feeling of great serenity. (eurekalert.org)
  • That said, ketamine is not without its dangers, and some researchers think the positive effects we get from microdosing may be down to a placebo effect. (dazeddigital.com)
  • British researchers followed 150 subjects for a year, and found that heavy ketamine use results in substantial cognitive impairments. (choosehelp.com)
  • Researchers at the University College London wanted to know what effect ketamine use had on memory, so they recruited 150 study subjects to find out. (choosehelp.com)
  • My concern was that although depressed patients certainly do report feeling better after an injection of ketamine, compared to people given placebo , that doesn't prove that the drug is actually an antidepressant. (discovermagazine.com)
  • Rather, patients might be experiencing an enhanced, 'active' placebo effect , because ketamine causes subjectively powerful hallucinogenic experiences. (discovermagazine.com)
  • While on ketamine people experienced significant subjective effects, with AZD6765 they didn't, and couldn't tell whether they got drug or placebo. (discovermagazine.com)
  • All of the participants received an infusion of ketamine twice - once after receiving naltrexone and again after receiving a placebo in place of the opioid-blocker. (livescience.com)
  • Procedures ensured participant and staff blinding, with no notable demographic differences between those receiving ketamine or a placebo. (news-medical.net)
  • Notably, to my knowledge, there have been no controlled studies comparing ketamine (via infusion or other modality) with an active control (ie, a drug that produces some al-teration in consciousness beyond the placebo effect of saline). (psychiatrictimes.com)
  • Patients received a single infusion of ketamine or midazolam (as an active placebo) in addition to standard of care. (nih.gov)
  • The difference is small, and it's difficult to blind because it causes a dissociative state - people wig out - so it's clear when someone has received ketamine and when someone has received a placebo. (stanford.edu)
  • We did not see any serious, drug-related adverse events or increased ketamine cravings with a single administration. (medicalnewstoday.com)
  • Emergence reaction is an adverse reaction to PCP and ketamine use seen during the recovery phase. (msdmanuals.com)
  • Main outcomes included reasons for ESM- Ketamine activations and ketamine -related adverse events. (bvsalud.org)
  • Also, because some people use ketamine recreationally, some experts are worried about the drug's potential for abuse. (medicalnewstoday.com)
  • This is very different in comparison to how ketamine is often used recreationally where there might be loud music, an unfamiliar dark environment, and potentially unsafe variables. (psychologytoday.com)
  • If you take ketamine recreationally, it's likely you'll have to take more to get the same effects. (dazeddigital.com)
  • A 2011 clinical practice guideline supports the use of ketamine as a sedative in emergency medicine, including during physically painful procedures. (wikipedia.org)
  • A video (watch below) shows undercover agents buying ketamine, a sedative used in veterinary medicine, in a busy shopping district in central Lima. (insightcrime.org)
  • My PANDAS daughter, age 11, was recently given Ketamine as a sedative to insert her central line for Plasmapheresis. (latitudes.org)
  • 1 2 Ketamine has an antidepressant effect that is unconventionally swift and that does not apparently involve monoaminergic pathways. (bmj.com)
  • if ketamine has a specific antidepressant effect, it should produce more improvement than the comparison drug. (discovermagazine.com)
  • Primary objective: 1) verification of the rapid antidepressant effect of psilocybin compared to ketamine using the MADRS scale at 24 hours. (centerwatch.com)
  • Es" is actually the name of the mirror image of ketamine, [and] this how it gets its name. (hcplive.com)
  • Ketamine has also been show to inhibit receptors in a way that when used with other drugs is used to control pain. (petplace.com)
  • But it is a less powerful trapping blocker than ketamine, meaning that AZD6765 causes less dramatic effects on the target receptors, in some respects. (discovermagazine.com)
  • Patients pay cash because most insurers don't cover non-surgical uses of ketamine, none of which are approved by the Food and Drug Administration. (ktar.com)
  • Ketamine was first synthesized in 1962 and approved for use in the United States in 1970. (wikipedia.org)
  • Ketamine is not technically a psychedelic, but it has dissociative effects that can cause hallucinations, confusion, and euphoria. (psychcentral.com)
  • WASHINGTON (AP) - As U.S. doctors scale back their use of opioid painkillers, a new option for hard-to-treat pain is taking root: ketamine, the decades-old surgical drug that is now a trendy psychedelic therapy. (ktar.com)
  • Ketamine therapy is a type of therapeutic psychedelic drug therapy. (veteranstoday.com)
  • Ketamine has shown "rapid and robust antidepressant effects," in clinical studies. (medscape.com)
  • However, "since the review is based on a small sample, a low risk of psychosis exacerbation after IV ketamine is still possible," said Iosifescu, who is also the director of clinical research at the Kline Institute for Psychiatric Research in Orangeburg, New York, and was not involved with the study. (medscape.com)
  • While ketamine is often administered through an IV drip or taken orally in clinical settings, these don't really work for people self-medicating. (dazeddigital.com)
  • Though the study had its limitations, it's the first in a series of follow-up ketamine studies that will include larger demographics and a wider range of clinical histories across a larger number of subjects over a longer period of time. (psychcentral.com)
  • From the point of view of clinical practicability, subcutaneous, intranasal, and oral ketamine warrant further study. (psychiatrist.com)
  • Such efforts will enable the field to more accurately assess the potential of ketamine, as well as its limitations, allowing for appropriate placement within the context of comprehensive clinical care for suicide prevention. (nih.gov)
  • Also excluded were patients who were transported outside the medical system, patients whose emergency department clinical course could not be ascertained, and those who received haloperidol and benzodiazepines after ketamine had been was available. (ems1.com)
  • The repurposing of ketamine for use in mental disorders is a noteworthy yet disputed development in psychiatry over the past two decades. (bmj.com)
  • 1. When and how did ketamine first make an appearance in psychiatry? (stanford.edu)
  • When Gulur and her colleagues tracked 300 patients receiving ketamine at Duke, more than a third of them reported significant side effects that required professional attention, such as hallucinations, troubling thoughts and visual disturbances. (ktar.com)
  • The effect of ketamine on the respiratory and circulatory systems is different from that of other anesthetics. (wikipedia.org)
  • apalutamide will decrease the level or effect of ketamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
  • Patients will often have a more beneficial experience with ketamine in a safe and supportive space than in recreational environments. (psychologytoday.com)
  • This is a report of my worst experience with ketamine ( + kratom) and generally one of my worst drug experiences. (erowid.org)
  • As with most anesthetics, after administration of ketamine, the eyes remain open and unable to blink. (petplace.com)
  • Heinzerling, who treats individuals at his clinic with ketamine-assisted psychotherapy (KAP), explained that absorption and bioavailability are reliable in both methods (Heinzerling administers intramuscular injections in his practice). (psychcentral.com)
  • Tune in Monday for Dr. Mandel's tips on selecting a reputable ketamine infusion clinic. (prnewswire.com)
  • As a potential patient, when they come across your ketamine clinic online or within your search results, you want them to feel comfortable and compelled to visit your website or contact you for further information. (prlog.org)
  • MADRS-SI score was lower in the ketamine group compared to midazolam group at 24 h (p = 0.05). (nih.gov)
  • The main goal is to compare the antidepressant effects of psilocybin and ketamine in patients with TRD versus the antidepressant inactive substance midazolam. (centerwatch.com)
  • Psilocybin, Ketamine Hydrochloride, Midazolam Ph. (centerwatch.com)
  • In practice, this makes AZD6765, much less hallucinogenic than ketamine. (discovermagazine.com)
  • Ketamine is an addictive stimulant/hallucinogenic drug (club drug). (choosehelp.com)
  • At lower doses ketamine has a pain-relieving effect, and its use in adult humans is mainly restricted to field situations such as frontline pain-relief for injured soldiers or victims of road traffic accidents. (eurekalert.org)
  • Ketamine is approved for use in humans, cats and primates. (petplace.com)
  • Ketamine is likely to be most beneficial for surgical patients when severe post-operative pain is expected and for opioid-tolerant patients. (wikipedia.org)
  • Ketamine acts in part via an opioid mechanism. (stanford.edu)
  • Drinking alcohol in addition to using ketamine is commonplace at these events. (arlingtoncemetery.net)
  • One study published in the journal Human & Experimental Toxicology found that the long-term use of ketamine and alcohol was so toxic that significant liver damage was common among participants. (arlingtoncemetery.net)
  • All of these issues were seen with long-term ketamine use and were drastically increased when alcohol use was a factor as well. (arlingtoncemetery.net)
  • Though ketamine alone can cause all of these issues, the problems are worsened when alcohol is used in combination with the drug. (arlingtoncemetery.net)
  • Mahjoubi's practice is typical of the burgeoning industry: He offers IV ketamine for alcohol addiction, chronic pain, anxiety and post-traumatic stress disorder. (ktar.com)
  • New research contends that ketamine can reduce problematic alcohol use but does the data support the claims? (madinamerica.com)
  • Ketamine HCl is soluble 1 g in 4 mL of water, 14 mL of alcohol, and 60 mL of absolute alcohol. (uspharmacist.com)
  • For some stupid reason I thought I would self-medicate with ketamine, as it s been shown to be effective as a fast acting antidepressant. (erowid.org)
  • Ketamine was chosen for the study because it is widely used as a safe anaesthetic and pain-relief drug for treating large animals including dogs, horses and sheep. (eurekalert.org)
  • Ketamine, on the other hand, is relatively new to the drug scene. (arlingtoncemetery.net)
  • Ketamine is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian. (petplace.com)
  • Ketamine should not be used in animals with known hypersensitivity or allergy to the drug. (petplace.com)
  • Ketamine can be a great drug," said Dr. Ronald Harbut in a recent phone interview. (cityweekly.net)
  • Ketamine comes with a "unique set of risks, both to the individual but also to society" including the potential for drug abuse and unknown effects of frequent use, especially at higher levels. (cnn.com)
  • Contrary to widely-held belief, a new rigorous trial finds that ketamine is ineffective for delirium and pain associated with surgery, and the drug carries harmful side effects. (madinamerica.com)
  • Ketamine has been a popular recreational drug in Europe and Asia for some years, and can be taken in liquid or powder form. (insightcrime.org)
  • The ketamine bust follows the recent seizure of thousands of synthetic drug capsules in Lima , including Ecstasy, MDMA, and 2CB - stimulants and hallucinogens which are typically used by young people at nighclubs or raves, as is ketamine. (insightcrime.org)
  • Ketamine is now reportedly available in Argentina, El Salvador and Uruguay as well as Peru, according to the United Nations 2012 World Drug Report. (insightcrime.org)
  • Strictly Come Dancing star Michelle Visage has shared how her daughter and husband were treated using illegal party drug ketamine in new therapy. (metro.co.uk)
  • Ketamine, the drug itself or the medication is actually quite inexpensive. (hcplive.com)
  • Ketamine for prehospital use: new look at an old drug. (ems1.com)
  • Ketamine has similar efficacy to opioids in a hospital emergency department setting for management of acute pain and for control of procedural pain. (wikipedia.org)
  • We conducted a randomized, controlled trial of ketamine in patients with mood and anxiety spectrum disorders who presented with clinically significant SI (n = 24). (nih.gov)