• With helpful illustrations, photos, figures, models that explain viral mechanisms, and easy-to-understand reference tables, Plant Viruses As Molecular Pathogens will stimulate your thinking on this fascinating area of plant science! (routledge.com)
  • Toxicodynamics is the study of the cellular and molecular mechanisms of the action of a poison [University of Arizona Emergency Medicine Research Center 2003]. (cdc.gov)
  • In addition to the host regulatory mechanisms response to disease, the microbiome can make changes to the expression of the host features such as their genes, proteins, and/or PTMs. (rsc.org)
  • The host inhales "B. bronchiseptica" and colonizes on the muccous membranes lining the respiratory tract and produces factors that counteract the host's defense mechanisms. (kenyon.edu)
  • However, little is known regarding the molecular and cellular mechanisms that regulate the processes and efficiency of transmission. (usda.gov)
  • Altogether, results of this project will provide insight into determinants and mechanisms used by the economically important group of soybean plants to maintain the integrity of specialized, root-derived organs, an aspect that is relevant also in the light of ongoing attempts to engineer non-legumes into rhizobial hosts. (europa.eu)
  • however, the underlying molecular mechanisms influencing such obesity-related pathways are poorly understood. (frontiersin.org)
  • This report contributes significantly to the current knowledge about the molecular mechanisms involved in the highly dynamic seaweed-bacterium interactions. (asm.org)
  • We will examine the molecular mechanisms by which microbial pathogens colonize the human body and cause disease. (sfu.ca)
  • Recent projects have included the molecular engineering of viruses, and the mechanisms of bacterial pathogenicity and host colonisation. (reading.ac.uk)
  • The current lack of understanding of the molecular mechanisms of key host-virus interactions that potentiate disease pathogenesis or impede disease potential through evasion of host cellular immunity, hampers the development of novel therapeutic strategies for arenavirus infection. (nottingham.ac.uk)
  • We are currently investigating the mechanisms of host restriction of arenavirus entry that may inform novel strategies to design therapeutic agents that utilise the host cell antiviral immunity to block emerging arenaviruses. (nottingham.ac.uk)
  • It remains to be discovered what drives the observed difference in phenotypes and what mechanisms govern the disparate responses to the host innate immune defence. (nottingham.ac.uk)
  • These findings provide a framework for future studies examining the molecular mechanisms underlying the pathogenicity of avian H7N9 virus. (aacc.org)
  • The study results provide valuable viral-host interaction between H7N9 and NHBE cells, which improves our understanding of the pathogenic mechanisms that lead to severe complications. (aacc.org)
  • The Breunig Laboratory is investigating the molecular mechanisms that govern the generation of the central nervous system from neural stem cells. (cedars-sinai.edu)
  • We now propose to use molecular approaches combined with unbiased forward genetic screening to elucidate mechanisms by which SLFN2 enforces T-cell quiescence. (europa.eu)
  • The molecular mechanisms behind the bacteria-induced formation of fibrinopeptides were investigated and shown to be triggered by the activation of the contact system, also known as the kallikrein/kinin system or the intrinsic pathway of coagulation. (lu.se)
  • These factors can contribute to adherence and multiplication at an epithelial surface, evasion of immune defense mechanisms or invasion into host cells and tissue. (lu.se)
  • The last decade has seen remarkable advances in plant virological research, owing mainly to the rapid progress made in molecular biology and genetic engineering in recent years. (routledge.com)
  • ab a Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, 4301 West Markham Street (slot 516), Little Rock, AR 72205-7199, USA. (rsc.org)
  • The use of state-of-the-art genetic approaches (including transcriptomics, phenomics, epigenomics, whole genome association studies, next generation sequ encing, exome sequencing, & systems biology) to identify and validate (including in vitro models, animal models, & human samples) viral and host genetic factors which influence the pathophysiology of HAND are encouraged. (nih.gov)
  • We will combine plant molecular genetics, cell biology with transcriptomics and metabolomics to unravel cells, genes and metabolic networks that contribute to the checkpoint system ensuring nodule integrity. (europa.eu)
  • Nematode Caenorhabditis elegans ( C. elegans ) is a extensively used as a powerful model organism for physiological, cell division, molecular biology and many other researches ( 25 ), and provide a perfect model to study the interaction between intestine and other organic systems ( 26 , 27 ). (frontiersin.org)
  • Another important factor is the molecular biology within your cells. (sflorg.com)
  • Alex is a molecular biologist seeking to incorporate computational biology into the study of infectious disease and host-pathogen interactions. (broadinstitute.org)
  • Before joining the Broad Institute, he received his PhD in Molecular and Evolutionary Systems Biology from the University of New Hampshire where he studied genome evolution and population dynamics of Staphylococcus species. (broadinstitute.org)
  • Understanding what governs these properties at the molecular level is crucial for stem cell biology and its application to regenerative medicine. (lu.se)
  • My research is on the evolution and ecology of host-pathogen interactions, especially population genetics of invertebrate hosts of Chagas' disease and whirling disease. (uvm.edu)
  • These investigationsuse molecular ecology, population genetics, and complex systems modeling. (uvm.edu)
  • 2010: Best oral presentation Award at the 10th International Conference on Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases, Amsterdam, The Netherlands. (africamuseum.be)
  • Both genetics and environmental factors influence the expression of asthma, and not all asthma is the result of a specific immune response to allergen. (cdc.gov)
  • Both host factors (genetics) and low molecular weight allergens. (cdc.gov)
  • Here you'll find new and useful information about plant molecular virology and how the field can improve the world food situation in the coming years. (routledge.com)
  • Our studies range from basic molecular & cellular virology to clinical studies in HPV testing & therapeutics. (gla.ac.uk)
  • To this end, we employ a range of molecular virology techniques including CRISPR/Cas9, mass spectrometry and next-generation sequencing. (google.com)
  • The book contains cutting-edge research in plant molecular virology, including pathogenic viroids and transport by insect vectors, interference with transmission to control viruses, synergism with pivotal coverage of RNA silencing, and the counter-defensive strategies used by viruses to overcome the silencing response in plants. (researchandmarkets.com)
  • The focus of this initiative is to encourage studies to discover novel genetic paradigms that may account for the interactions between the virus, the host, and the therapeutic drugs in the central nervous system (CNS) that result in the pathogenesis, progression, and clinical manifestations of HAND. (nih.gov)
  • Our work focusses on developing understanding of virus-host interactions by visualising them in a frozen-hydrated state at macromolecular resolution using cryo-electron tomography (cryo-ET). (gla.ac.uk)
  • We explore the intricate structural interactions between viruses and host complexes during virus infection and immune response, which is crucial for exploiting them and uncovering new avenues for the development of therapeutics. (gla.ac.uk)
  • The Courtney lab studies influenza A virus-host interactions with a focus on post-transcriptional regulation of viral RNA by host proteins. (google.com)
  • We investigate how the virus interacts with the host at a molecular level, and whether these interactions are conserved across multiple species. (google.com)
  • Our goal is to use our understanding of influenza virus-host interactions to advance our knowledge of the virus and develop new tools for combatting it. (google.com)
  • This balance is maintained by microbial diversity, genetic factors, and complex molecular-cellular interactions between host and microbiome. (uni-ulm.de)
  • The IMPALA project investigate the impact of agricultural land-use intensification through the use of organic and inorganic fertilizers on the microbiome and its functional interactions with hosts along a trophic cascade in grassland ecosystems. (uni-ulm.de)
  • The project thus provides important information on the effects of fertilization on the stability of an ecosystem, which are mediated through host-microbiome interactions. (uni-ulm.de)
  • This new edition introduces new, emerging proteins involved in host-virus interactions and provides in-depth coverage of plant virus genes' interactions with host, localization and expression. (researchandmarkets.com)
  • The ability to recognize and respond to the presence of microbes is an essential strategy for seaweeds to survive in the marine environment, but understanding of molecular seaweed-microbe interactions is limited. (asm.org)
  • Molecular interactions between ACE2-S and TMPRSS2-Sare crucial and preciously mediated by specific residues. (ias.ac.in)
  • Of particular relevance is to elucidate those molecular interactions which govern the reprogramming of somatic cells into ESC. (lu.se)
  • Our study reveals a novel pathway of small guide RNA maturation and the first example of a host factor (RNase III) required for bacterial RNA-mediated immunity against invaders. (nature.com)
  • How it all begins: Bacterial factors mediating the colonization of invertebrate hosts by beneficial symbionts. (mpg.de)
  • The molecular strategies that bacterial and viral pathogens use to colonize the human body and cause disease will be studied. (sfu.ca)
  • She is currently using comparative genomics and transcriptomics to identify bacterial and host factors that govern Salmonella persistence. (broadinstitute.org)
  • The inflammatory response to bacterial infection is the result of a complex interplay between bacterial products and host effector systems, such as the immune and complement systems. (lu.se)
  • Bacterial cell wall components and toxins, for example, are well-known virulence factors for sepsis that directly contribute to the profound dysregulation of the immune response. (lu.se)
  • Aliyari, R. & Ding, S. W. RNA-based viral immunity initiated by the Dicer family of host immune receptors. (nature.com)
  • The National Institute of Mental Health (NIMH) and The National Institute of Neurological Disorders and Stroke (NINDS) solicit research grant applications to supp ort studies focused on viral and host genetic factors involved in HIV-1 Associated Neurocognitive Disorders (HAND) in the setting of highly active anti-retroviral therapy (HAART). (nih.gov)
  • We are particularly interested in the role of host proteins in regulating viral gene expression, and how this affects the virus' ability to cause disease. (google.com)
  • Our research focusses on viral entry processes, evolution in the face of host immunity and virion assembly. (gla.ac.uk)
  • Molecular Approaches and Viral Evolution. (researchandmarkets.com)
  • Plant Virus-Host Interaction: Molecular Approaches and Viral Evolution, Second Edition, provides comprehensive coverage of molecular approaches for virus-host interaction. (researchandmarkets.com)
  • Viral factors (such as differences in the strain of a virus) play a role in this variability, but they cannot account for the wide range of responses in different individuals infected by the same virus. (sflorg.com)
  • By considering these changes in transposable elements after viral infection, they could identify several transcription factors (proteins that turn specific genes "on" or "off") that likely contribute to someone's response to infection. (sflorg.com)
  • Proteolytic cleavage of viral spike (S)-protein and ACE2 byTMPRSS2 began the entire host-pathogen interaction initiated with the physical binding of ACE2 to S-protein. (ias.ac.in)
  • Host restriction factors are components of the intrinsic anti-viral response, that act at crucial steps to potently inhibit viral entry, replication and exit from the host cell. (nottingham.ac.uk)
  • Despite the high genetic similarity amongst arenavirus strains, disease can vary from asymptomatic to fatal implying that the interplay between the host immune response and viral replication is a major predictive factor for disease outcome. (nottingham.ac.uk)
  • Professor Asogun's efforts pioneered the establishment of the molecular diagnostic laboratory at ISTH in 2008, serving as the first National Reference laboratory for viral haemorrhagic fevers in Nigeria, and he has made significant contributions to Lassa fever case management in Nigeria. (nottingham.ac.uk)
  • Normal human bronchial epithelial (NHBE) cell cultures have been an effective model to assess the viral-host interaction. (aacc.org)
  • Although bats serve as reservoir hosts with great viral diversity, little evidence exists for corresponding death or illness of bats from viruses (other than lyssaviruses) that have spread into humans and domesticated mammals with high virulence. (cdc.gov)
  • All of the virulence factors of "B. bronchiseptica" allow it to weaken the host's immune defenses, leading to infection. (kenyon.edu)
  • BvgA and BvgS, two-component regulatory systems, regulate these virulence factors. (kenyon.edu)
  • The overall questions driving my research center on understanding the ecological and genetic factors contributing to variation in infection and virulence. (uvm.edu)
  • My studies includes a rich assortment of topics, including host-pathogen population dynamics, vector feeding and host specificity, the evolution of virulence, and the costs of resistance and defense. (uvm.edu)
  • Emphasis will be placed on the specific microbes and their virulence factors, secretion systems, toxins and surface adhesions. (sfu.ca)
  • Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is at present an emerging global public health crisis.Angiotensin converting enzyme 2 (ACE2) and trans-membrane protease serine 2 (TMPRSS2) are the two major host factors that contributeto the virulence of SARS-CoV-2 and pathogenesis of coronavirus disease-19 (COVID-19). (ias.ac.in)
  • Abby has worked on comparative genomics projects of many different bacteria, including analyses of whole genome sequences of M. tuberculosis , Enterococcus , Fusobacterium , E. coli , and other microbes, with particular emphasis on the evolution of drug resistance and virulence factors. (broadinstitute.org)
  • Distinct pathogens use a diverse arsenal of molecular weapons to establish infection, designated virulence factors. (lu.se)
  • Enhanced understanding of pathogen derived virulence attributes can facilitate development of novel anti-infectives aimed at distinct virulence factors. (lu.se)
  • Here, we propose to decipher the molecular determinants that maintain determinate nodule identity using the B. diazoefficiens - soybean model. (europa.eu)
  • Plant Viruses As Molecular Pathogens is the only book to bring you all of this information--22 chapters--in a single volume, compiled by specialists around the globe! (routledge.com)
  • Tafesse Lab focuses on identifying and characterizing the host factors that are used by pathogens to secure invasion, persistence and propagation. (virginia.edu)
  • Additionally, we aim to apply novel strategies such as the use of single-domain antibodies/nanobodies not only to unravel the intricate relationships of these pathogens with the host, but also to use as diagnostic and therapeutics tools. (virginia.edu)
  • All cellular components that are involved in sensing extracellular factors affect the srfA operon. (wikipedia.org)
  • This may indicate that the insect vector is responding to cellular, biochemical, and/or physiological changes in the host plant that are brought about by virus infection rather than directly by virus exposure. (usda.gov)
  • Hosts of new applications have turned the light microscope into an exquisitely sensitive measuring device that can be used to image dynamic cellular events right down to the molecular level. (the-scientist.com)
  • With contributions from leading experts, this is a comprehensive reference for plant virologists, molecular biologists and others interested in characterization of plant viruses and disease management. (researchandmarkets.com)
  • His Ph.D. was on the molecular characterization of sugarcane viruses, i.e., mosaic, streak mosaic, and yellow luteovirus. (researchandmarkets.com)
  • This issue will be addressed by undertaking molecular characterization of EAggEc isolates from patients in whom 'host factors' which may be related to EAggEc pathogenesis can be measured. (usda.gov)
  • 2015. Characterization of Arabidopsis transcriptional responses to different aphid species reveals genes that contribute to host susceptibility and non-host resistance . (hutton.ac.uk)
  • Full-genome based molecular characterization of encephalitis-associated bovine astroviruses. (cdc.gov)
  • These factors consist of certain cell surface proteins and transcription factors that induce the uptake of DNA. (wikipedia.org)
  • The obvious next step is to integrate this information and learn how genes, proteins, and/or epigenetic factors influence the phenotype of a disease in context of the system. (rsc.org)
  • This difference in autotransporter proteins could possibly contribute to the bacteria's host specificity and the different diseases they cause [9]. (kenyon.edu)
  • These structural proteins may also be required to facilitate entry to and exit from the host cell, as well as packaging the genome and the necessary functional proteins. (gla.ac.uk)
  • Structural stability, binding affinity and level of expression of these threeinteracting proteins are key susceptibility factors for COVID-19. (ias.ac.in)
  • During development, a host of signaling pathways, in the form of proteins on neighboring cells or soluble factors, influence the behavior of these cells. (cedars-sinai.edu)
  • Here we show that Escherichia coli bacteria expressing fibrous surface proteins, known as curli, assemble and activate factors of the human coagulation cascade at their surface. (lu.se)
  • These vectors have a number of appealing features including the expression by using the machinery of the host cell instead of depending abilities to ef®ciently transduce cells in the central nervous system, on recombinant regulatory proteins. (lu.se)
  • Insects are the most important epidemiological factors of plant virus disease spread, with >75% of the viruses dependent on insects for host transmission. (usda.gov)
  • The black-faced leafhopper (Graminella nigrifrons) vectors two viruses that use different strategies for host transmission: the semi-persistently transmitted Maize chlorotic dwarf virus and the persistent propagatively transmitted Maize fine streak virus. (usda.gov)
  • In their replication cycle, viruses must generate a protective shell (or capsid) to ferry their genome between hosts. (gla.ac.uk)
  • Molecular studies have demonstrated that bats are natural host reservoirs for several recently emerged high-profile zoonotic viruses. (cdc.gov)
  • A recent comparative analysis, showed bats to be more likely to be infected with more zoonotic viruses per host species than were rodents, thus adding weight to the suggestion that bats might in some way be unique as sources of emerging zoonoses. (cdc.gov)
  • performed a comparative analysis of viruses in bats and rodents and associated ecologic factors. (cdc.gov)
  • The analysis indicated that bats are indeed special in hosting more viruses per species than rodents, despite twice as many rodent species in the world, and that certain ecologic factors are associated with the hosting of more viruses by bats. (cdc.gov)
  • 2) elucidate key molecular processes in T-cells regulated by SLFN2 by a forward genetic screen. (europa.eu)
  • This information will be used to test the importance of genes involved in the common response for virus transmission, and may ultimately be useful for identifying insect factors that disrupt insect-mediated virus transmission to crops. (usda.gov)
  • Environmental factors like toxins and stress can actually alter our genes (pdf), creating changes in our brains that last a lifetime. (theroot.com)
  • Subsequent genomic sequence analysis of multiple genes including elongation factor 3, a component of fungi protein synthesis not found in protozoa, further supported this notion. (medscape.com)
  • Differential expression of specific factors observed between avian H7N9 and pdmH1N1 influenza virus strains could explain the variation in disease pathogenicity. (aacc.org)
  • We will illustrate how, through surveying the metabolites that broker microbe-host interaction, metabolomics can enrich insights into this association. (triconference.com)
  • While rather deep molecular insights into plant-rhizobia recognition, early nodule organogenesis, regulation of nodulation and nitrogen fixation are available, much less is known about how nodule integrity is maintained and the origin of the underlying morphogenetic program. (europa.eu)
  • When this reading frame is expressed, it will activate the transcription factor ComK. (wikipedia.org)
  • We propose a computational model of the embryonic stem cell network, in which a core set of transcription factors (TFs) interact with each other and are induced by external factors. (lu.se)
  • Intestinal immunity is the bedrock of host health and holistic health maintained by nutrition and the existence of the host supported by immunity. (intechopen.com)
  • The gastrointestinal immune barrier is exposed to the environment or food, and immunity is maintained by several factors. (intechopen.com)
  • In the proposed chapter, we will discuss the molecular impact of dietary fibers on intestinal immunity and how innate immune response and gut microbiota are regulated by metabolites. (intechopen.com)
  • Epigenetic changes such as DNA methylation may be a molecular mechanism through which environmental exposures affect health. (cdc.gov)
  • Our results uncover the structural basis for foreign DNA capture and the mechanism by which Cas1-Cas2 functions as a molecular ruler to dictate the sequence architecture of CRISPR loci. (berkeley.edu)
  • In this chapter, we will focus on dietary fibers, which interact directly with gut microbes and lead to the production of metabolites and discuss how dietary fiber impacts gut microbiota ecology, host physiology, and health and molecule mechanism of dietary fiber on signaling pathway that linked to the host health. (intechopen.com)
  • Even where diagnosed by history, medical examina- hyper homocysteinaemia is a well estab- tion, electrocardiogram, echocardiogram lished risk factor, we do not know the exact and blood tests, including enzymes (tro- mechanism whereby high homocysteine ponin T and creatine phosphokinase). (who.int)
  • To date, however, there are very few hard data about EAggEc that permit speculation about the molecular basis for pathogenesis or development of additional diagnostic methodologies. (usda.gov)
  • None of the other work that has been done to date on serogroups of EAggEc strains, entero or cytotoxins, invasive ability, clump formation or hemagglutinins can explain the pathogenesis of diarrhea associated with these organisms or serve as a definitive means of identifying clinically important EAggEc strains as these factors have not been identified in the majority of EAggEc strains from various geographic locations. (usda.gov)
  • However, studies dedicated to understanding the molecular components of the immune response in seaweeds are rare and restricted to indirect stimulus. (asm.org)
  • Sepsis occurs when the interacting networks of the host immune response fail to contain the infection at the local site, resulting in a dysregulated and systemic immune response. (lu.se)
  • Features such as the transcriptome, methylome, proteome, histone post-translational modifications and the microbiome all influence the host response to various diseases and cancers. (rsc.org)
  • Its functional composition is crucial for the sensitive balance between microbiome and host. (uni-ulm.de)
  • While the mutual relationships between host and microbiome in specific ecological niches have been extensively studied, little is known about the influence of environmental changes on microbiome functions in complex ecosystems. (uni-ulm.de)
  • Environmental factors, such as organic or inorganic fertilization, directly affect the soil microbiome by altering the nutritional and physico-chemical properties of the soil and consequently shaping the microbiome of roots, leaves and flowers. (uni-ulm.de)
  • Mark is an associate computational biologist interested in the relationship between host and microbiome. (broadinstitute.org)
  • Since route of allergen exposure can influence mechanistic pathways, mice were sensitized by identical routes with a high molecular weight occupational allergen ovalbumin and a low molecular weight occupational allergen trimellitic anhydride (TMA). (cdc.gov)
  • But these findings are an important step toward understanding the role that such factors play in the variability of illness severity among individuals. (sflorg.com)
  • Distinct genomic variability exists between host-specific members of the genus. (medscape.com)
  • Host hydrocarbons protect symbiont transmission from a radical host defense. (mpg.de)
  • These innate immune responses use a variety of germline-encoded receptors to discriminate between microbial and host cell surfaces, or infected and normal cells. (nih.gov)
  • Human evidence of this is provided by molecular analysis of Pneumocystis isolates obtained from groups of patients involved in hospital outbreaks. (medscape.com)
  • Most infectious agents show a significant degree of host specificity , causing disease only in one or a few related species. (nih.gov)
  • What determines host specificity for every agent is not known, but the requirement for attachment to a particular cell-surface molecule is one critical factor. (nih.gov)
  • Thus virus particles are dynamic entities, molecular machines evolved to provide a robust protective shell for the genome and capable of undergoing dramatic conformational changes upon infection of a host cell and in response to specific environmental stimuli. (gla.ac.uk)
  • Examples of high molecular environmental factors are known to influence the development weight occupational allergens include proteases used in the and expression of asthma, and a vast array of triggers of asthma detergent industry, laboratory animal allergens, and ovalbumin have been identified. (cdc.gov)
  • Host factor TIMP1 sustains long-lasting myeloid-biased hematopoiesis after severe infection. (bvsalud.org)
  • Bordetella bronchiseptica" can infect a wide range of hosts causing different diseases and is most commonly found in canines, pigs, and laboratory animals [2]. (kenyon.edu)
  • Only when a microorganism has successfully established a site of infection in the host does disease occur, and little damage will be caused unless the agent is able to spread from the original site of infection or can secrete toxins that can spread to other parts of the body. (nih.gov)
  • Our research aims to identify host factors that are important for influenza virus replication and spread, which could lead to the development of new antiviral strategies. (google.com)
  • The interaction between "B. bronchiseptica" and its host is pathogenic. (kenyon.edu)
  • We have also demonstrated how an integration host factor helps Cas1-Cas2 recognize the CRISPR array for site-specific integration. (berkeley.edu)
  • Impact of intraspecific variation in insect microbiomes on host phenotype and evolution. (mpg.de)
  • Predictive factors of cervical metastasis are primary site, primary tumor size, degree of differentiation of tumor, perineural invasion, perivascular invasion, inflammatory response, and tumor DNA content (ploidy). (medscape.com)
  • Thus, our data establish TIMP1 as a molecular reporter of past infection in the host, sustaining hyper myelopoiesis and serving as a potential therapeutic target for modulating HSPC cell fate. (bvsalud.org)
  • Thus all the factors for parasite transmission may be concen- longipalpis from other biting flies in urban ZVL foci suggests trated within a relatively small area. (cdc.gov)
  • The bacterium is characterized as a facultative parasite in which it is capable of surviving for an extensive amount of time outside of a host. (kenyon.edu)
  • Infectious disease can be devastating, and sometimes fatal, to the host. (nih.gov)
  • In the first stage, a new host is exposed to infectious particles shed by an infected individual. (nih.gov)
  • The number, route, mode of transmission, and stability of an infectious agent outside the host determines its infectivity. (nih.gov)
  • Factors that may influence links may also aid in choosing an appropriate drug regimen for transmission include prolonged hours of contact during the the contact before cultures and sensitivity test results are avail- infectious period, close proximity to the person with TB, and able (5). (cdc.gov)
  • Last but not least, the use of antibiotics in agriculture is an important factor in the worldwide spread of antibiotic resistance and leads to an increasing number of infections in plants, livestock, wild animals and humans by antibiotic-resistant bacteria. (uni-ulm.de)
  • The ability of a cell to successfully incorporate exogenous DNA, or competency, is determined by competence factors. (wikipedia.org)
  • An acute graft-versus-host disease activity index to predict survival after hematopoietic cell transplantation with myeloablative conditioning regimens. (nature.com)
  • Prospective evaluation for upper gastrointestinal tract acute graft-versus-host disease after hematopoietic stem cell transplantation. (nature.com)
  • After induction, hADSCs expressed von Willebrand Factor (vWF), the cell marker of ECs. (molvis.org)
  • Although Kupffer cells are considered the primary cells to respond to pathogen associated molecular patterns in the liver, recent studies provide evidence of TLR signaling in hepatic nonimmune cell populations, including hepatocytes, biliary epithelial cells, endothelial cells, and hepatic stellate cells. (nih.gov)
  • A stochastic treatment of the network dynamics suggests that NANOG heterogeneity is the deciding factor for the stem cell fate. (lu.se)
  • Our model also hosts reprogramming of a committed cell into an ESC by over-expressing OCT4. (lu.se)
  • 2000). We of glial cell line-derived neurotrophic factor (GDNF) in models of have recently reported that this vector directs transgene expression to Parkinson's disease (Georgievska et al. (lu.se)
  • Changes in gene expression that occur independent of the mode of pathogen transmission could be important for identifying insect factors that disrupt vector-mediated plant virus transmission. (usda.gov)
  • Oral beclomethasone dipropionate for treatment of human intestinal graft-versus-host disease. (nature.com)
  • VK2 is mainly produced by gut bacteria, suggesting that VK2 might facilitate communication between the gut microbiota and the host intestinal cells to influence fat metabolism. (frontiersin.org)
  • Vitamin K2 (VK2) is commonly produced by gut bacteria and is fat-soluble, allowing it to be easily transferred into the host intestinal cells ( 14 ). (frontiersin.org)
  • Many of the tory indicate that this species has no strong innate host prefer- inhabitants raise chickens, pigs, and other livestock in their ence. (cdc.gov)
  • Keeping nodules in check: Interplay of rhizobial and host factors controlling nodule morphogenesis and identity in legume plants. (europa.eu)
  • B. bronchiseptica" expresses many protein factors, such as filamentous haemagglutinin (FHA), pertactin and fimbriae. (kenyon.edu)
  • Modelled protein-protein interaction (PPI) predicted strong molecular interaction between these two receptors and SARS-CoV-2 spike protein (S1 domain). (ias.ac.in)
  • ABSTRACT This study investigated the role of hyperhomocysteinaemia as a risk factor in Sudanese adults suffering from cardiovascular disease or malaria and children with protein-energy malnutrition. (who.int)
  • Interestingly, soybean nodules elicited by a Bradyrhizobium diazoefficiens mutant lacking the general stress response sigma factor σEcfG also formed ectopic roots (host's project), pointing to a bacteria-plant signalling system that is crucial for nodule persistence and integrity. (europa.eu)
  • is indisputable, Host loyalty involving subpopulations of vectors would have a marked effect on Leishmania transmission (7). (cdc.gov)
  • The first contact with a new host occurs through an epithelial surface. (nih.gov)
  • In this study, we aimed to assess host differentially expressed gene signatures in respiratory tract epithelial cells after influenza A virus pdmH1N1 or H7N9 infection. (aacc.org)
  • As the cancer volume increases, the cancer may release angiogenesis factors, such as vascular endothelial growth factor (VEGF), which promote formation of new blood vessels that are required for further growth. (msdmanuals.com)