• The β-chain of DQ is encoded by HLA-DQB1 locus and DQ2 are encoded by the HLA-DQB1*02 allele group. (wikipedia.org)
  • [ 18 ] Furthermore, CD4 + T cell responses in patients who have recovered from HBV are greater in those who carry the HLA-DRB1*1302 allele. (medscape.com)
  • Allele and haplotype frequencies for HLA-DQ in Iranian celiac disease patients. (cdc.gov)
  • DQ2 β-chains combine with α-chains, encoded by genetically linked HLA-DQA1 alleles, to form the cis-haplotype isoforms. (wikipedia.org)
  • This haplotype, HLA A1-B8-DR3-DQ2, is associated with diseases in which HLA-DQ2 has suspect involvement. (wikipedia.org)
  • DQB1*0201 in Europe is frequently found in the HLA A1-B8-DR3-DQ2 haplotype. (wikipedia.org)
  • The haplotype is linked to DR7. (wikipedia.org)
  • The HLA DRB locus alleles DRB1*1301/2 are consistently associated with spontaneous resolution of infection in sub-Saharan African, Asian, and Caucasian populations. (medscape.com)
  • It is possible that the quality or magnitude of the T-cell response induced by HLA-DRB1*1302 is superior to other alleles. (medscape.com)
  • [ 19 ] Alternatively, HLA-DRB1*1302 may present a wider range of epitopes than other alleles. (medscape.com)
  • We aimed to investigate the relationship between human leukocyte antigens (HLA)-groups and clinical features, and degree of intestinal injury in children with celiac disease (CD). (nih.gov)
  • Influence of HLA-DQ2 and DQ8 on severity in celiac Disease. (cdc.gov)
  • A new PCR-SSP method for HLA DR-DQ risk assessment for celiac disease. (cdc.gov)
  • HLA and celiac disease susceptibility: new genetic factors bring open questions about the HLA influence and gene-dosage effects. (cdc.gov)
  • HLA class II high-resolution genotyping in Greek children with celiac disease and impact on disease susceptibility. (cdc.gov)
  • Human leukocyte antigen DQ2.2 and celiac disease. (cdc.gov)
  • HLA-DQA1 and HLA-DQB1 in Celiac disease predisposition: practical implications of the HLA molecular typing. (cdc.gov)
  • The role of HLA DQ2 and DQ8 in dissecting celiac-like disease in common variable immunodeficiency. (cdc.gov)
  • HLA genotyping in pediatric celiac disease patients. (cdc.gov)
  • HLA-DQ2/DQ8 and HLA-DQB1*02 homozygosity typing by real-time polymerase chain reaction for the assessment of celiac disease genetic risk: evaluation of a Spanish celiac population. (cdc.gov)
  • HLA Genotyping: Methods for the Identification of the HLA-DQ2,-DQ8 Heterodimers Implicated in Celiac Disease (CD) Susceptibility. (cdc.gov)
  • [ 3 , 4 ] As the human leucocyte antigen (HLA) molecules encoded by MHC class II are responsible for presenting peptide epitopes to CD4 + T helper cells, it is reasonable to postulate that polymorphism in the MHC class II region may explain the variation in outcome. (medscape.com)
  • DQ2.5 isoform or heterodimer is shorthand for the cell surface receptor HLA-DQ α5β2. (wikipedia.org)
  • HLA A30, C14, DR11, DQ3 frequency were lower in patients compared to both control groups. (nih.gov)
  • HLA-DQ2 (DQ2) is a serotype group within HLA-DQ (DQ) serotyping system. (wikipedia.org)