Homologous graft. Medical search. Frequent questions

The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin. (lookformedical.com)

Scholars@Duke publication: Novel Scoring Criteria for the Evaluation of Ocular Graft-versus-Host Disease in a Preclinical Allogeneic Hematopoietic Stem Cell Transplantation Animal Model. (duke.edu)

One-year graft survival was 89.1% in OKT3 and 89.2% in CYS (p = .19). (emmes.com)
In multivariate analysis, OKT3 had a numerically inferior graft survival (RR = 1.4, CI 0.8-2.2, p = 0.22). (emmes.com)
In OKT3 graft survival was inferior for children aged 6 yr or younger. (emmes.com)
The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. (lookformedical.com)
Regulatory T cells (Treg) can induce and maintain antigen-specific immune tolerance and facilitate allogeneic graft survival successfully in animals. (ox.ac.uk)
The skin graft survival was observed 3-5 days after skin grafting, and the wound healing time was recorded. (bvsalud.org)
Long term follow up will be needed to assess temporal complications and long term survival of the graft. (jbstjournal.com)
In some transplantation settings, achieving B cell as well as T cell tolerance will be essential in order to ensure long-term graft survival. (ox.ac.uk)
Background & Aims: Autoimmune hepatitis can recur after liver transplantation (LT), though the impact of recurrence on patient and graft survival has not been well characterized. (mssm.edu)
We evaluated a large, international, multicenter cohort to identify the probability and risk factors associated with recurrent AIH and the association between recurrent disease and patient and graft survival. (mssm.edu)
Conclusion: Recurrence of AIH following transplant is frequent and is associated with younger age at LT, use of mycophenolate mofetil post-LT, sex mismatch and high IgG pre-LT. We demonstrate an association between disease recurrence and impaired graft and overall survival in patients with AIH, highlighting the importance of ongoing efforts to better characterize, prevent and treat recurrent AIH. (mssm.edu)

Ocular complications occur after transplantation in 60% to 90% of chronic graft-versus-host disease (GVHD) patients and significantly impair vision-related quality of life. (duke.edu)

However, in immune privileged sites, tissue grafts can survive for extended periods of time without rejection occurring. (wikipedia.org)
Acute rejection leading to renal graft failure is more frequent among children. (emmes.com)
Our trial demonstrates that the incidence of acute rejection or graft failure in pediatric patients is not improved by OKT3 induction therapy relative to cyclosporine induction. (emmes.com)
It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (lookformedical.com)
Switching the balance from rejection of major histocompatibility-mismatched grafts toward long-term tolerance of donor grafts, with the need for minimal immunosuppressive drugs, is a major transplantation goal. (ox.ac.uk)

Simultaneous implantation of bilateral ureters into bladder acellular matrix graft after partial cystectomy in a porcine model. (ucsf.edu)
Nerve growth factor combined with vascular endothelial growth factor enhances regeneration of bladder acellular matrix graft in spinal cord injury-induced neurogenic rat bladder. (ucsf.edu)
Functional improvement in spinal cord injury-induced neurogenic bladder by bladder augmentation using bladder acellular matrix graft in the rat. (ucsf.edu)
Effect of vascular endothelial growth factor on regeneration of bladder acellular matrix graft: histologic and functional evaluation. (ucsf.edu)
In 30 male Sprague-Dawley rats, a 0.3 to 0.8-cm midsegment of the left ureter was resected and replaced with an acellular matrix graft of equal length placed on a polyethylene stent. (escholarship.org)
In all animals, the acellular matrix graft remained in its original position without evidence of incrustation or infection, and histologic examination showed complete epithelialization and progressive infiltration by vessels. (escholarship.org)
The ureteral acellular matrix graft appears to promote the regeneration of all ureteral wall components. (escholarship.org)

Graft-versus-host disease (GVHD) remains a significant complication in patients undergoing allogeneic stem cell transplantation (SCT) using a reduced intensity conditioning regimen. (qub.ac.uk)
Purpose: Diarrhea associated with acute gastrointestinal (GI) graft- versus-host disease (GVHD) after allogeneic bone marrow transplantation (BMT) can result in severe morbidity and mortality. (elsevierpure.com)
When a transplant occurs which includes lymphocytes, monocytes or progenitors thereof, particularly bone marrow, a graft may attack the host as foreign, resulting in graft-versus-host disease. (justia.com)
Special request products such as designated blood donation from first-degree relatives should not be used because of the risk of transfusion-associated graft versus host disease. (northwestern.edu)
Although T-cell depletion is increasingly used to reduce the risk of graft-versus-host disease its impact on the graft-versus-leukemia effect and long-term outcome post-transplant is unknown. (ox.ac.uk)
Graft-versus-host disease (GVHD) prophylaxis was with cyclosporine A alone. (ox.ac.uk)
In very rare cases, though, blood from family members can cause a condition called graft-versus-host disease. (medlineplus.gov)

[ 3 ] In 1896, Israel applied a tibial bone graft to the nose. (medscape.com)
Treatment of intraosseous periodontal defects with a combined adjunctive therapy of citric acid conditioning, bone grafting, and placement of collagenous membranes. (thejcdp.com)
Both are working with MTF Biologics, which also claims non-profit status and says it focuses on bone and skin grafts. (medpagetoday.com)
After bone maturation and bone neoformation secondary to alveolar osteogenic osteogenic distraction and segmental osteotomy with autologous graft interposition, respectively, the two presented case reports were able to securely receive dental implants. (bvsalud.org)

However, in other situations, although B cell tolerance could potentially offer advantages to the long-term function of the graft and may therefore be desirable, there is no evidence that inducing B cell tolerance alongside T cell tolerance is essential. (ox.ac.uk)

Longitudinal evaluation of free autogenous gingival grafts. (thejcdp.com)
Free autogenous gingival grafts. (thejcdp.com)
Autogenous non-vascularised fibular graft for reconstruction of distal radius GCTcan be considered as a reasonable option for treating such conditions. (jbstjournal.com)

Although T-cell depletion (TCD) reduces the risk of GVHD after a myeloablative conditioning regimen, it is associated with an increased risk of graft failure. (qub.ac.uk)

one treated with alveolar osteogenesis distraction and the other with segmental osteotomy with autologous graft interposition, by describing the surgical steps as well as show the results and experiences acquired with these techniques. (bvsalud.org)
Alveolar osteogenic distraction is highly advisable when vertical deficiency is severe, and if these cases are treated with the segmental osteotomy and autologous graft interposition, complications as graft failure, necrosis and resorption are more prone to occur due to insufficient vascularization. (bvsalud.org)

Tissue grafts are normally recognised as foreign antigens by the body and attacked by the immune system. (wikipedia.org)
Subepithelial connective tissue graft technique for root coverage. (thejcdp.com)
Coronal positioning of tissue previously treated with freeze-dried dura mater grafts. (thejcdp.com)
Tissue reaction involving an intraoral skin graft and CP titanium abutments: a clinical report. (thejcdp.com)
An induced state of non-reactivity to grafted tissue from a donor organism that would ordinarily trigger a cell-mediated or humoral immune response. (lookformedical.com)

The allograft reconstruction was used in arthrodesis in 44 cases (41 knees, three ankles), as an intercalary graft in 39 (28 femurs, 11 tibias), as an osteoarticular graft in 22 (three proximal and/or distal humeri, six distal femurs, 13 proximal tibias), and as an allograft and prosthesis composite in seven (two proximal humeri, one proximal femurs, four proximal tibias). (lww.com)
The combined treatment produced robust CST regeneration directly through the grafts and into distal spinal cord. (biorxiv.org)
We studied 5 consecutive cases of GCT involving the distal radius operated by en-bloc resection of tumor followed by reconstruction with ipsilateral non-vascularized fibular graft with a minimum 1 year follow-up. (jbstjournal.com)

Regeneration of Corticospinal Axons into Neural Progenitor Cell Grafts After Spinal Cord Injury. (ccf.org)

bi-iliac prosthetic graft reconstruction (day 0). (cdc.gov)
The limited availability of homologous grafts for reconstruction of the auditory chain stimulated the quest for new prosthetic medical devices. (stenobooks.com)

In addition, embryonic stem cells may be modified by homologous recombination for use in producing chimeric or transgenic mammalian hosts, which may be used as source of universal donor organs. (justia.com)
There were no complications both at donor and recipient graft sites. (jbstjournal.com)

UMR_S 1109, Strasbourg (F. Danion) struction using a silver-coated prosthetic aorto-bi-il- iac graft. (cdc.gov)
Obstruction of flow in biological or prosthetic vascular grafts. (lookformedical.com)

BACKGROUND: Reduced intensity conditioning regimens permit the delivery of a potentially curative graft-versus-leukemia effect in older patients with acute myeloid leukemia. (ox.ac.uk)
These data confirm the presence of a potent graft-versus-leukemia effect after a T-cell depleted reduced intensity conditioning allograft in acute myeloid leukemia and identify CsA exposure as a manipulable determinant of outcome in this setting. (ox.ac.uk)

At final follow up of minimum 1 year, all cases had good graft union with no recurrence. (jbstjournal.com)

Investigating these areas will help us to bridge spinal cord injury sites with the help of cellular grafts, establishing a patient's functional recovery from injury. (ccf.org)
Here, using a murine model of spinal injury, we elevated the intrinsic regenerative ability of CST neurons by supplying a pro-regenerative transcription factor, KLF6, while simultaneously supplying injured CST axons with a growth-permissive graft of neural progenitor cells (NPCs) transplanted into a site of spinal injury. (biorxiv.org)
Recent work involving transplants of neural progenitor cells has also succeeded in creating novel relay circuits as host axons invade and innervate graft-derived neurons, which in turn extend lengthy axons that innervate neurons in the caudal spinal cord ( 7 - 9 ). (biorxiv.org)

Dermal graft harvest technique for use in temporomandibular joint disc repair. (thejcdp.com)
Moreover, the absence of a dermal component in these grafts predisposes to instability and contracture. (ox.ac.uk)
A cross-linked collagen and glycosaminoglycan dermal substitute, covered with thin split-skin grafts or cultured autologous keratinocytes, shows promise in burns patients. (ox.ac.uk)

Homologous recombination is employed to inactivate genes, particularly genes associated with MHC antigens. (justia.com)
or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity. (lookformedical.com)

A clinical evaluation of freeze-dried homologous dura mater as a periodontal free graft material. (thejcdp.com)

Dashwood MR, Loesch A. Inducible nitric oxide synthase and vein graft performance in patients undergoing coronary artery bypass surgery: physiological or pathophysiological role? (surgery.by)
We have reviewed the impact of evolving issues in coronary artery bypass grafting (CABG) on transfusion support for these patients. (northwestern.edu)
However, evidence suggests that transfusion practice in coronary artery bypass grafting procedures remains variable and does not take into account the results of recently published clinical studies. (northwestern.edu)
Institutions with coronary artery bypass grafting programs should establish a multidisciplinary approach to use a combination of interventions designed to minimize homologous blood exposure. (northwestern.edu)

The second area of study is to understand the regulation of the immune response to cellular and solid organ grafts. (stanford.edu)

the patient had retroperitoneal rales, is a rare, life-threatening fungal infection necrosis with false necrotic membranes, another di- whose incidence has been rising since the late 1990s gestive fistula, and graft exposure (Figure, panel C). (cdc.gov)
C) Intraoperative view shows the graft exposure and false necrotic membranes. (cdc.gov)

Although the vascular tropism of Mucorales is well resection-anastomosis and omentoplasty to cover described, few cases of cardiovascular infections have the graft. (cdc.gov)

Full-thickness skin grafting of post surgical oral defects: shortand long-term outcomes. (thejcdp.com)

In patients treated with T cell antibody induction, retrospective data from the pediatric registry show a 22% reduction in the risk of graft failure. (emmes.com)
Through 4 yr, graft failure was 27% in OKT3 and 19% in CYS (p = 0.15). (emmes.com)

For patients with no nasal airway obstruction and minor-to-moderate nasal dorsal saddling, onlay grafting techniques can be used. (medscape.com)
The placement of spreader grafts is usually sufficient to address the internal nasal valve and middle vault collapse. (medscape.com)

Learn and practice the pronunciation of homologous. (shabdkosh.com)

Issues include increased awareness of transfusion risks, reappraisal of traditional indicators triggering transfusion, and evolving alternatives to homologous blood transfusion such as autologous blood and pharmacologic therapy. (northwestern.edu)

After 3 weeks of dressing change, the wound was covered with split-thickness skin graft from the lateral thigh on the affected side. (bvsalud.org)

The animals were killed at varying intervals, and the grafted specimens were prepared for light and electron microscopy. (escholarship.org)

The first-line treatment for mucormycosis is li- graft and then using a cryopreserved human al- posomal amphotericin B (5 mg/kg) ( 8 ). (cdc.gov)
Utilization of grafts in the treatment of gingival recession. (thejcdp.com)

The clinical application of cultured grafts remains imperfect but offers the prospect of immediate coverage and massive expansion. (ox.ac.uk)

Cases of direct viral transmission from the graft itself have been reported ( 6 , 7 ). (cdc.gov)

This graft technique uses the body's own irradiated rib cartilage from a rib bank. (tamiralife.com)

To evaluate ureteral replacement by a free homologous graft of acellular matrix in a rat model. (escholarship.org)

Anatomy52

Organisms13

Diseases43

Chemicals and Drugs29

Analytical, Diagnostic and Therapeutic Techniques and Equipment101

Phenomena and Processes19

Disciplines and Occupations1

Technology, Industry, Agriculture12

Information Science3

Named Groups1

Health Care23

Humans1

Hematopoietic Stem Cell Trans1

Survival11

Chronic graft-versus-1

Rejection5

Acellular matrix graft7

Disease7

Bone4

Tolerance1

Autogenous3

GVHD1

Autologous Graft2

Tissue5

Distal3

Regeneration1

Reconstruction2

Donor2

Prosthetic2

Acute2

Recurrence1

Spinal3

Dermal3

Antigens2

Evaluation1

Coronary4

Immune1

Membranes2

Vascular1

Surgical1

Failure2

Nasal2

Practice1

Alternatives1

Skin1

Animals1

Treatment2

Clinical1

Transmission1

Technique1

Free1