Homeostatically regulated. Medical search. Frequent questions

Regulated cell death (RCD) plays an essential role in cell homeostasis, tissue remodeling, and diseases. (invivogen.com)

Two molecules linked to synaptic plasticity regulate the intensity of the first deep sleep stage. (jneurosci.org)
Next, endocannabinoid signaling that regulates synaptic plasticity is discussed as a key mechanism acting both at hypothalamic and mesolimbic circuits, and affecting both dopamine function and interplay between leptin and ghrelin signaling. (frontiersin.org)

This is where he should have mentioned leptin signaling, and the circuits in the brain that regulate body fat mass, which would have taken the book in a more compelling direction. (blogspot.com)
You probably already know that our fat mass is homeostatically regulated by the hormone leptin. (humanos.me)

The volume of body fluid, blood glucose, oxygen, and carbon dioxide levels are also tightly homeostatically maintained. (wikipedia.org)
Many critical attributes within our bodies are controlled homeostatically, core body temperature and blood pH levels being two of the better known examples, with body fluid balance being another that is tightly regulated this way. (triathlete.com)

There is increasing evidence that body weight is homeostatically regulated and that in obesity this regulation maintains weight at a high level. (drugbank.com)
The control of DNA-supercoiling in S. pneumoniae occurs mainly via the regulation of topoisomerase gene transcription: relaxation triggers the up-regulation of gyrase and the down-regulation of topoisomerases I and IV, while hypernegative supercoiling down-regulates the expression of topoisomerase I. Relaxation affects 13% of the genome, with the majority of the genes affected located in 15 domains. (ucm.es)

DEL-1 is a locally secreted 52-kDa protein that interacts with distinct integrins and homeostatically regulates the initiation and resolution of inflammation (18 - 25). (web.app)
Retinol-binding protein (RBP) binds vitamin A and regulates its absorption and metabolism. (medscape.com)

Two examples of factors that are regulated homeostatically are temperature and water content. (utoronto.ca)

core bodily temperature is an example of being homeostatically maintained within narrow limits despite major variations in the external temperature. (treasury-management.com)
For example, an organism needs to regulate body temperature through the thermoregulation process. (utoronto.ca)
Examples of internal conditions maintained homeostatically are the level of blood glucose, body temperature, blood calcium level. (utoronto.ca)

Produced by the liver, hepcidin is a 25 amino acid peptide hormone that circulates in plasma and homeostatically controls body iron balance. (ashpublications.org)

An active research program is underway to develop new agents based on the rapidly expanding knowledge of the complex mechanisms regulating body weight. (drugbank.com)

As in mammals, the timing and intensity of these dynamic sleep processes in flies is homeostatically regulated and modulated by behavioral experience. (jneurosci.org)

We previously reported that the expression of Del-1 is positively regulated by p53 in lung endothelial cells. (web.app)

[8] The evolutionary conservation of type I IFN subtypes binding the same IFNAR receptor at the same site with differing affinities suggests that type I IFNs are nonredundant and potentially regulate different cellular responses. (wikidoc.org)
[2] [11] Efforts to engineer a more potent IFNα2 elicited a cellular response similar to IFNβ, suggesting that the affinity of type I IFNs for IFNAR has an important role in regulating the downstream response. (wikidoc.org)

According to literally thousands of publications spanning nearly two centuries, the brain is the only organ that is known to regulate body fat mass in humans and other animals-- neither fat tissue itself, nor the insulin-secreting pancreas have the ability to regulate body fat mass as far as we currently know. (blogspot.com)
Every vertebrate, from the time of conception till the time of death, literally has all body systems homeostatically regulated by endocannabinoids (marijuana-like compounds produced by the body). (medicalmarijuana411.com)

Insulin is made from proinsulin, but the extent to which fasting/feeding controls the homeostatically-regulated proinsulin pool in pancreatic β-cells remains largely unknown. (pasteur.fr)

Parental genome is important to the extent that it can determine whether a gene is either homeostatically regulated or not, in response to sleep loss. (fpwr.org)
Based on its response to relaxation, the pneumococcal chromosome can be said to be organized into five types of domain: up-regulated, down-regulated, position-conserved non-regulated, position-variable non-regulated, and AT-rich. (ucm.es)

1 Iron levels in turn regulate hepcidin production: in healthy individuals, hepcidin production increases when plasma or tissue iron concentrations rise and decreases after iron depletion. (ashpublications.org)

If indeed the gravitostat regulates energy balance by picking up on changes in body weight, you would think that weightlessness would lead to greater body fat, right? (humanos.me)

BACKGROUNDThe locus coeruleus (LC) is the primary source of norepinephrine in the brain and regulates arousal and sleep. (bvsalud.org)
The video discusses how play is homeostatically regulated, how it is connected to the brain stem, and how it produces small amounts of opioid release. (summarize.tech)

Moreover, by regulating the effective connectivity and local E/I balance, modular topographic precision enables the system to gradually improve its internal representations and increase signal-to-noise ratio as the input signal passes through the network. (bernstein-network.de)

or it may have emotional effects, which influence neurotransmitters and neuropeptides, which in turn helps to regulate the immune system--the healer within. (thephilosophie.com)

The amount of SWA is homeostatically regulated, increasing after wakefulness and returning to baseline during sleep. (nih.gov)
The amount of REM sleep you get is controlled homeostatically. (somnustherapy.com)

Sleep has a strong effect on levels of some hormones such as growth hormone but little effect on others which are more strongly regulated by the circadian timing system (e.g., melatonin). (nih.gov)
Under normal circumstances, behaviors and the circadian timing system are synchronized with an optimal phase relationship and consequently hormonal systems are exquisitely regulated. (nih.gov)

We have identified genes required for ER expansion and determined how they regulate lipid metabolism and ER membrane biogenesis ( Papagiannidis, Bircham et al, 2021 ). (db-engine.de)
ascorbate peroxidase) and as well as regulating the key stress-responsive genes (OsSOD1, OsPOD1, OsCAT2, OsAPX1), thereby reinstate cellular membrane integrity and confer tolerance to ultrastructural damages under Cd-induced phytotoxicity. (bvsalud.org)

Expression of hepcidin is homeostatically regulated by anaemia hypoxia inflammation [13] and also by the function of the hemochromatosis protein (HFE) hemojuvelin (HJV) and TfR2 as indicated by their mutation that decreased hepcidin expression [14-16]. (biotech2012.org)
We therefore investigated how catecholamine synthesis is regulated under hypoxia stress [1- 1] . (kyoto-u.ac.jp)

These coupled positive and negative feedback loops homeostatically maintain the widespread Emc expression that keeps the Da expression low, through buffering Da activity, opposing bHLH protein dependent differentiation in most imaginal disc cells while enhancing cell growth and survival. (yu.edu)
In conclusion, our studies established a novel cross-interacting network that regulates expression and activities of the E-proteins and Id-proteins. (yu.edu)

To explain the foundation that underpins a living system's ability to self-regulate its internal environment requires investigation of the foundation that underpins the very activity of living itself, including evolutionary forces enabling self-organization and autonomous self-serving behavior (see Life ). (citizendium.org)
Our goal is to understand how this nutrient-driven mechanism regulates stem cell behavior for lifelong optimization of organ form and function. (stanford.edu)

This focus reflects the unique aspects and incredible diversity of lipids and their associated enzymes in regulating signaling pathways, membrane environments, metabolic pathways, and gene transcription to affect physiology and pathophysiology. (grc.org)
8. Deubiquitinating enzymes regulate PARK2-mediated mitophagy. (nih.gov)

Retinol-binding protein (RBP) binds vitamin A and regulates its absorption and metabolism. (medscape.com)

Neural patterning is attributed to highly regulated transcription of specific proneural bHLH transcription factors (Scute, Achaete, Atonal in Drosophila and their homologs Mash, Math, Neurogenins etc.) that define neuronal progenitor cells. (yu.edu)

it may entrain biological systems to function more homeostatically, it may calm the mind and therefore the body, or it may have emotional effects, which influence neurotransmitters and neuropeptides, which in turn help to regulate the immune system - the healer within. (igli.me)

This feature is characteristic of living things, which continually repair themselves and homeostatically regulate their temperatures and the balance of chemicals present in their tissues. (bbntimes.com)
4. This result, and a literature survey, suggest that each heterotrophic bacterial strain regulates its elemental composition homeostatically within a relatively narrow range of characteristic biomass C:P and N:P ratios. (elsevierpure.com)

The CB2 receptors are found predominantly on immunological cells and regulate the shift in the immune system to the anti-inflammatory mode. (ganjavibes.com)

Sleep is homeostatically regulated where the duration of wakefulness drives subsequent sleep. (alladalab.org)
Sleep is homeostatically regulated, i.e., sleep is driven by the duration and intensity of prior waking experience. (alladalab.org)

Apoptosis was the first well-defined process of regulated cell death [1-3]. (invivogen.com)
It is triggered either homeostatically (e.g. during embryonic development), or upon exposure to a variety of insults (e.g. engagement of TNF (tumor necrosis factor) family death domain receptors at the cell surface). (invivogen.com)
Pyroptosis is a form of regulated necrotic cell death that results from inflammasome activation [4, 5]. (invivogen.com)
Although it is clear that chronic antigen contributes to CD8 T cell exhaustion, less is known about how stress responses in tissues regulate T cell function. (salk.edu)

Startling, but not too surprising once you realize that the ARE system is homeostatically regulated. (gettingstronger.org)
Bodies are homeostatically maintained by the Cannabinoid System. (ganjavibes.com)

Homeostatically regulated slow-wave oscillations in non-rapid eye movement (REM) sleep may reflect synaptic changes across the sleep-wake continuum and the restorative function of sleep. (nih.gov)

The volume of body fluid, blood glucose, oxygen, and carbon dioxide levels are also tightly homeostatically maintained. (wikipedia.org)

Other variables include the pH of extracellular fluid , the concentrations of sodium , potassium , and calcium ions , as well as the blood sugar level , and these need to be regulated despite changes in the environment, diet, or level of activity. (wikipedia.org)

A generally accepted definition is that sleep is a state of greatly reduced responsiveness and movement that is homeostatically regulated, meaning that when it is prevented for a period of time, the lost time is made up-an effect known as sleep rebound. (the-scientist.com)

In case of iron depletion iron release from the storage cells is mediated by FPN1 [10] and regulated via hepcidin [11]. (biotech2012.org)

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Psychiatry and Psychology2

Phenomena and Processes3

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Leptin2

Tightly2

Regulation2

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Temperature3

Hormone1

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Body weight1

Brain2

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Circadian2

Genes2

Hypoxia2

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Cell4

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