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  • protein
  • Putative genes that are regulated by NK-2 protein were cloned and were sequenced partially. (nih.gov)
  • A nuclear protein was found that binds to a novel trinucleotide repeat sequence in the 5'-upstream region of a rat brain voltage-sensitive calcium channel a1 subunit that activates an enhancerless chloramphenicol acetyltransferase reporter gene. (nih.gov)
  • genes
  • Four Pou-domain genes expressed in embryonic and adult mouse brain were cloned and sequenced: Brain-1, Brain-2, Brain-4, and Scip. (nih.gov)
  • ANTP
  • Based on the partial homeobox sequences we cannot unambiguously distinguish between Scr and Antp homeobox fragments in Diplura, Archaeognatha, Ephemeroptera, Odonata, Plecoptera and Dermaptera. (nih.gov)
  • In this study, we report a method for the fast and efficient retrieval of sequences belonging to the ANTP (HOXL and NKL) and PRD classes. (beds.ac.uk)
  • homologs
  • Note that all new sequences group to expected homologs. (nih.gov)
  • A Neighbour Joining analysis of only the six potentially unambiguous new homeobox sequences (lab, pb, Dfd, Ubx, Abd-B) groups all new fragments into the expected clades of homologs from other insects and thus confirms the results of NCBI Blast (Fig. 2), except for abd-A which appears paraphyletic. (nih.gov)
  • Nematostella
  • For four of the Nematostella homeodomains, there is disagreement between neighbor-joining and Bayesian trees regarding their class membership. (biomedcentral.com)
  • Fifty-six homeodomain families found in human and/or fruit fly are also found in Nematostella , though seventeen families shared by human and fly appear absent in Nematostella . (biomedcentral.com)
  • Furthermore, at least one portion of the protein has been extremely highly conserved - e.g ., only two of the 60 positions in the homeodomain differ between Nematostella (a sea anemone) and Branchiostoma (a chordate), two taxa that diverged over 600 million years ago. (biomedcentral.com)
  • TALE
  • In the absence of the TALE class homeodomain cofactors Exd and Hth, Ubx and Abd-A bind at a very similar set of target sites in accessible chromatin, whereas Abd-B binds at an additional specific set of targets. (biomedcentral.com)
  • regulatory
  • The striking functional equivalence of Hox3 paralogues was most dramatically demonstrated by swapping the Hoxa3 and Hoxd3 protein coding sequences, leaving the regulatory regions intact ( 15 ). (pnas.org)
  • Expressing either protein under the control of the other's regulatory sequences resulted in a WT phenotype, providing strong evidence that these two proteins are functionally equivalent despite their different single mutant phenotypes and diverged protein sequences. (pnas.org)
  • nucleotide
  • The invention further provides vectors comprising nucleotide sequences that encode LMP, as well as host cells comprising those vectors. (google.com)
  • Moreover, the present invention relates to methods of inducing bone formation by transfecting osteogenic precursor cells with an isolated nucleic acid molecule comprising a nucleotide sequence encoding LIM mineralization protein. (google.com)
  • In a particular embodiment, the invention provides a method of fusing a spine by transfecting osteogenic precursor cells with an isolated nucleic acid molecule having a nucleotide sequence encoding LIM mineralization protein, admixing the transfected osteogenic precursor cells with a matrix and contacting the matrix with the spine. (google.com)
  • 1. A method of inducing bone formation comprising transfecting osteogenic precursor cells with an isolated nucleic acid molecule comprising a nucleotide sequence encoding LIM mineralization protein, wherein said nucleic acid molecule is SEQ ID NO: 22 or SEQ ID NO: 33. (google.com)