• Mammalian LH-2, a transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types. (embl.de)
  • The canonical TGFβ signalling pathway involves ligand-dependent assembly of a heteromeric receptor complex, receptor-kinase activation and subsequent phosphorylation and activation of SMAD proteins, which are transcriptional regulators that consequently accumulate in the nucleus. (nature.com)
  • A ubiquitously expressed sequence-specific transcriptional repressor that is normally the target of signaling by NOTCH PROTEINS. (harvard.edu)
  • A cellular transcriptional coactivator that was originally identified by its requirement for the stable assembly IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. (rush.edu)
  • A broad category of receptor-like proteins that may play a role in transcriptional-regulation in the CELL NUCLEUS . (nih.gov)
  • The encoded protein acts as a transcription factor and may be autoregulatory. (thermofisher.com)
  • A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. (bvsalud.org)
  • The Lhx1 transcription factor plays several roles during embryogenesis, regulating target genes expression by forming multiprotein complexes with LIM binding protein 1 (Ldb1). (bvsalud.org)
  • Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. (childrensmercy.org)
  • In addition to binding to RNA, nuclear factor 90 proteins form heterodimeric complexes that regulate GENETIC TRANSCRIPTION and may play a role in T-CELL activation. (ouhsc.edu)
  • C. elegans homeobox protein ceh-14. (embl.de)
  • C. elegans homeobox protein unc-97. (embl.de)
  • This analysis yielded a list of prospective organizer genes, and we determined the role of six-transmembrane domain containing transmembrane protein 150b (Tmem150b) in organizer function. (bvsalud.org)
  • It contains an N-terminal RING FINGER DOMAIN and is a PROTEIN PHOSPHATASE 1 regulatory subunit. (jefferson.edu)
  • Protein Phosphatase 4 Catalytic Subunit (PPP4C) is an evolutionarily conserved protein involved in multiple biological and pathological events, including embryogenesis, organogenesis, cellular homeostasis, and oncogenesis. (bvsalud.org)
  • In the three signal model, the dorsalizing signal from the organizer is mediated by bone morphogenic protein (BMP) gradients to give rise to cells of mesodermal fate. (wikipedia.org)
  • Using these devices, Otx2 and other head organizer TFs (for example, Lim1/Lhx1 (activator) or Goosecoid (repressor)) are able to upregulate or downregulate a large battery of target genes in the head organizer . (xenbase.org)
  • Nuclear Factor 90 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
  • Below are the most recent publications written about "Nuclear Factor 90 Proteins" by people in Profiles. (ouhsc.edu)
  • Leucine-Responsive Regulatory Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
  • This graph shows the total number of publications written about "Leucine-Responsive Regulatory Protein" by people in this website by year, and whether "Leucine-Responsive Regulatory Protein" was a major or minor topic of these publications. (rush.edu)
  • Below are the most recent publications written about "Leucine-Responsive Regulatory Protein" by people in Profiles. (rush.edu)
  • Rhombotin 1 (RBTN1 or TTG-1) and rhombotin-2 (RBTN2 or TTG-2) are proteins of about 160 amino acids whose genes are disrupted by chromosomal translocations in T-cell leukemia. (embl.de)
  • Proteína homeótica y factor de transcripción que se localiza en el núcleo celular donde activa la expresión de genes tiroideos específicos como el de la TIROGLOBULINA y el RECEPTOR DE TIROTROPINA. (bvsalud.org)
  • Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). (childrensmercy.org)
  • By tandem- affinity purification from kidney-induced Xenopus animal caps, we identified single-stranded DNA binding protein 2 (Ssbp2) interacts with the Ldb1-Lhx1 complex. (bvsalud.org)
  • Mammalian and avian cysteine-rich protein (CRP), a 192 amino-acid protein of unknown function. (embl.de)
  • Human recombinant protein fragment corresponding to amino acids 107-257 of human GSC produced in E.coli. (thermofisher.com)
  • Constam, D. B. & Robertson, E. J. Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. (nature.com)
  • Moreover, Tmem150b negatively regulated bone morphogenetic protein (BMP) signaling, likely via physical interaction with activin receptor-like kinase 2 (ALK2). (bvsalud.org)
  • a protein required for the differentiation of the set of six touch receptor neurons in this nematode. (embl.de)
  • They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. (embl.de)
  • Mammalian cysteine-rich intestinal protein (CRIP), a small protein which seems to have a role in zinc absorption and may function as an intracellular zinc transport protein. (embl.de)
  • A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis. (thermofisher.com)
  • Many of these proteins are similar in structure to known NUCLEAR RECEPTORS but appear to lack a functional ligand-binding domain, while in other cases the specific ligands have yet to be identified. (nih.gov)
  • Some LIM domains bind protein partners via tyrosine-containing motifs. (embl.de)
  • LIM domains coordinate one or more zinc atoms, and are named after the three proteins (LIN-11, Isl1 and MEC-3) in which they were first found. (embl.de)
  • Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. (embl.de)
  • Isl-1 binds to one of the two cis-acting protein-binding domains of the insulin gene. (embl.de)
  • a protein required for the asymmetric division of vulval blast cells. (embl.de)
  • In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (jefferson.edu)
  • Saccharomyces cerevisiae (Baker's yeast) rho-type GTPase activating protein RGA1/DBM1. (embl.de)
  • A LEUCINE and DNA-binding protein that is found primarily in BACTERIA and ARCHAEA. (rush.edu)
  • Drosophila melanogaster (Fruit fly) protein apterous, required for the normal development of the wing and halter imaginal discs. (embl.de)
  • Vertebrate homeobox proteins lim-1, lim-2 (lim-5) and lim3. (embl.de)
  • LAP is a homodimer which is disulfide linked to TGF-beta binding protein" /db_xref="CDD:pfam00688" mat_peptide 1679. (mit.edu)
  • Vertebrate paxillin, a cytoskeletal focal adhesion protein. (embl.de)
  • AN - coordinate IM with ADENOMA (IM) HN - 2006 BX - Corticotroph Adenoma BX - Pituitary Adenoma, ACTH-Secreting BX - Pituitary Corticotropin-Secreting Adenoma MH - Actin Capping Proteins UI - D051344 MN - D5.750.78.730.32 MN - D12.776.220.525.32 MS - Actin capping proteins are cytoskeletal proteins that bind to the ends of ACTIN FILAMENTS to regulate actin polymerization. (nih.gov)
  • The founding member of the nodal signaling ligand family of proteins. (lookformedical.com)
  • Mammalian cysteine-rich intestinal protein (CRIP), a small protein which seems to have a role in zinc absorption and may function as an intracellular zinc transport protein. (embl.de)
  • LOCUS BMP5 2207 bp mRNA linear PRI 08-NOV-2002 DEFINITION Homo sapiens bone morphogenetic protein 5 (BMP5), mRNA. (mit.edu)
  • Summary: This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. (mit.edu)
  • 2074 /gene="BMP5" /product="bone morphogenetic protein 5" misc_feature 1763. (mit.edu)
  • 2074 /gene="BMP5" /note="bone morphogenetic protein 5 proprotein" polyA_signal 2131. (mit.edu)
  • Suppression of bone morphogenetic protein (BMP) signaling induces neural induction in the ectoderm of developing embryos. (molcells.org)
  • Moreover, Tmem150b negatively regulated bone morphogenetic protein (BMP) signaling, likely via physical interaction with activin receptor-like kinase 2 (ALK2). (bvsalud.org)
  • Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. (lookformedical.com)
  • Some LIM domains bind protein partners via tyrosine-containing motifs. (embl.de)
  • They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. (embl.de)
  • Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. (lookformedical.com)
  • C. elegans homeobox protein ceh-14. (embl.de)
  • C. elegans homeobox protein unc-97. (embl.de)
  • Vertebrate insulin gene enhancer binding protein isl-1. (embl.de)
  • Vertebrate protein kinases LIMK-1 and LIMK-2. (embl.de)
  • Drosophila melanogaster (Fruit fly) protein apterous, required for the normal development of the wing and halter imaginal discs. (embl.de)
  • In the three signal model, the dorsalizing signal from the organizer is mediated by bone morphogenic protein (BMP) gradients to give rise to cells of mesodermal fate. (wikipedia.org)
  • HN - 2006(1998) MH - Actin-Related Protein 2-3 Complex UI - D051376 MN - D5.750.78.730.246 MN - D12.776.220.525.246 MS - A complex of seven proteins including ARP2 PROTEIN and ARP3 PROTEIN that plays an essential role in maintenance and assembly of the CYTOSKELETON. (nih.gov)
  • A protein which is a subunit of RNA polymerase. (nih.gov)
  • Protein Phosphatase 4 Catalytic Subunit (PPP4C) is an evolutionarily conserved protein involved in multiple biological and pathological events, including embryogenesis, organogenesis, cellular homeostasis, and oncogenesis. (bvsalud.org)
  • Isl-1 binds to one of the two cis-acting protein-binding domains of the insulin gene. (embl.de)
  • Arp2-3 complex binds WASP PROTEIN and existing ACTIN FILAMENTS, and it nucleates the formation of new branch point filaments. (nih.gov)
  • HN - 2006 BX - Arp2-3 Complex MH - Actin-Related Protein 3 UI - D051378 MN - D5.750.78.730.246.750 MN - D12.776.220.525.246.750 MS - A component of the Arp2-3 complex that is related in sequence and structure to ACTIN and that binds ATP. (nih.gov)
  • The boxed and bracketed areas represent the regions of PRH that interact with the proteins indicated. (biomedcentral.com)
  • Zyxin is a low-abundance adhesion plaque protein which has been shown to interact with CRP. (embl.de)
  • HN - 2006(1981) BX - Cofilins MH - Actin-Related Protein 2 UI - D051377 MN - D5.750.78.730.246.500 MN - D12.776.220.525.246.500 MS - A PROFILIN binding domain protein that is part of the Arp2-3 complex. (nih.gov)
  • It is expressed at higher levels than ARP2 PROTEIN and does not contain a PROFILIN binding domain. (nih.gov)
  • A tripartite motif protein that contains three ZINC FINGERS , including a RING FINGER DOMAIN , at its N-terminal. (nih.gov)
  • The PRH protein has a predicted molecular mass of 30 kDa, but in vivo and in vitro PRH forms homo-oligomeric complexes that appear to be octameric and hexadecameric [ 23 - 25 ]. (biomedcentral.com)
  • Many of these proteins have been the subject of scientific investigations in the area of MORPHOGENESIS and development. (lookformedical.com)
  • Proteins that are preferentially expressed or upregulated during FETAL DEVELOPMENT. (lookformedical.com)
  • Many of the proteins in this species have been the subject of studies involving basic embryological development (EMBRYOLOGY). (lookformedical.com)
  • This is consistent with the involvement of multiple PRH-interacting proteins, including the oncoprotein c-Myc, translation initiation factor 4E (eIF4E), and the promyelocytic leukaemia protein (PML), in the control of cell proliferation and cell survival. (biomedcentral.com)
  • Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. (embl.de)
  • Helianthus annuus (Common sunflower) pollen specific protein SF3. (embl.de)
  • Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. (mit.edu)