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  • homeotic
  • One of the principal differences between HTH motifs in these different proteins arises from the stereo-chemical requirement for glycine in the turn which is needed to avoid steric interference of the beta-carbon with the main chain: for cro and repressor proteins the glycine appears to be mandatory, whereas for many of the homeotic and other DNA-binding proteins the requirement is relaxed. (wikipedia.org)
  • cDNA
  • To construct theΔ 1-5 -pacap1b mutant, site-directed mutagenesis was used to delete the cDNA nucleotides encoding amino acids 121-125 of the PACAP1b precursor protein. (biologists.org)
  • complexes
  • Analysis of disassociation rates indicates that the Grf10-Swi5-DNA complex has a longer half-life than protein-DNA complexes that contain only Swi5 or Grf10. (pnas.org)
  • abstract
  • In his honor, we provide here an update of this review, although we will barely be able to scratch the surface, given that over 17,000 publications containing "homeobox," "homeodomain," or "Hox" in the title or abstract have appeared since the first publications. (springer.com)
  • TALE
  • We also find that previously identified stratum corneum gene transcriptional regulators are probably TALE proteins. (biologists.org)
  • Here we show that TALE proteins are abundant in the differentiating epidermis. (biologists.org)
  • Perturbation of TALE proteins in transgenic mouse epidermis substantially alters external but not internal stratum corneum and produces external skin barrier defects. (biologists.org)
  • motif
  • The PRD class comprises six families in Bilateria , and tinkers with four different motifs, i.e., the PAIRED domain, the Groucho-interacting motif EH1 (aka Octapeptide or TN), the homeodomain, and the OAR motif. (springer.com)
  • Homologs of the co-repressor protein Groucho are also present in plants (TOPLESS), where they have been shown to interact with small amphipathic motives (EAR), and in yeast (TUP1), where we find an EH1-like motif in MATα2. (springer.com)
  • roles
  • More structural data has also become available, and the characterization of the molecular roles of HD proteins has tremendously advanced. (springer.com)
  • development
  • The PRH/HHex transcription factor is an oligomeric protein that is required for multiple processes during early development including axis formation, haematopoiesis and development of the vasculature. (findaphd.com)
  • different
  • p>When browsing through different UniProt proteins, you can use the 'basket' to save them, so that you can back to find or analyse them later. (uniprot.org)