• Subset-specific Retention of Donor Myeloid Cells After Major Histocompatibility Complex-matched and Mismatched Liver Transplantation: Erratum. (bvsalud.org)
  • The use of human leukocyte antigen (HLA)-incompatible transplantations, in addition to cord blood transplantation, is rapidly increasing due to the development and refinement of graft-versus-host disease prophylactic treatment with post-transplant cyclophosphamide or anti-thymocyte globulin. (bvsalud.org)
  • This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. (wikipedia.org)
  • The minor histocompatibility antigen 13 is a nonamer peptide that originates from a protein encoded by the H13 gene. (wikipedia.org)
  • The protein encoded by the M13/HM13 gene is the signal peptide peptidase (SPP), an ER-resident intramembrane protease. (wikipedia.org)
  • The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. (nih.gov)
  • The peptide is generated by the cytosol by the proteasome, enters the endoplasmic reticulum (ER) lumen by the transporter associated with antigen processing (TAP) and is presented on the cell surface on H2-Db major histocompatibility antigen I (MHC I) molecules. (wikipedia.org)
  • As melanoma-specific CD8+ T cells have been shown to target melanocyte-specific peptide antigens more often than melanoma-specific antigens, we investigated whether vitiligo- and psoriasis-predisposing MHC-I alleles conferred a melanoma-protective effect. (bvsalud.org)
  • Selective genetic editing of human leucocyte antigen (HLA) molecules has been proposed to generate hESCs with immunocompatibility, which, however, has not been specifically designed for the Chinese population yet. (bvsalud.org)
  • This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. (wikipedia.org)
  • Gene symbols, accession ids and various other target identifiers. (nih.gov)
  • Approved gene symbol with link to HUGO Gene Nomenclature Committee. (nih.gov)
  • The class I major histocompatibility complex (MHC-I), which displays derivatives of the cellular peptidome for immune surveillance by CD8+ T cells, serves as a common genetic link between these conditions. (bvsalud.org)
  • Description of the protein which includes the UniProt Function and the NCBI Gene Summary. (nih.gov)