AllelesLociAlleleSNPsAntigensGene polymorphismsHaplotypesNucleotideGenome-WideHaplotypeRheumatoid arthritisPTPN22ExonAssociationPathogenesisType 1 diabetBinding proteinAmino acidRelationshipCytokinesChromosomeInfectionGenotypesAntigenAntibodyGenes associatedClassHumanUnclearViralRiskDiseaseVariantsImmune SystemClinicalArthritisAssociationsSuggests
Alleles23
- HLA class II alleles in Romanian patients with chronic hepatitis C. (cdc.gov)
- Associations of Human Leukocyte Antigen-DRB1 Alleles with Nasopharyngeal Carcinoma and Its Clinical Significance in Xinjiang Uyghur Autonomous Region of China. (cdc.gov)
- Differences in the frequencies of HLA-class I and II alleles between German patients with renal cell carcinoma and healthy controls. (cdc.gov)
- Several of these genes, such as TNC (near TNFSF15), CXCR6, and genes associated with IBD at the HLA locus, contained SNPs with unique association patterns with African-specific alleles. (njit.edu)
- Compared with other HLA-DRB1 alleles, HLA-DRB1*06, DRB1*08, and DRB1*16 may be associated with chronicity of HBV infection, HLA-DRB1*07 with protection against HBV infection, and HLA-DRB1*14 allele may be associated with a high rate of the response of CHB patients to IFN treatment.Compared with other HLA-DQB1 alleles, HLA-DQB1*07 may be associated with low response rate to IFN. (wanfangdata.com.cn)
- Allele frequencies were compared with published frequencies of HLA alleles from 11 755 unrelated northern Chinese Han bone marrow donors by Fisher's exact test. (blood-genomics.com)
- In this cohort, 13, 25 and 13 alleles were observed at HLA-A, -B, and -DRB1 loci respectively. (blood-genomics.com)
- The association between HLA alleles (A, B, DRB1), haplotypes and AIDS progression in HIV-1 infected patients was investigated by analyzing and comparing the differences gene frequencies of HLA alleles (A, B, DRB1) and haplotypes in HIV-1 infected and AIDS individuals in Hubei province of China. (blood-genomics.com)
- PMR is connected with HLA class II alleles, with the HLA-DRB1*04 allele correlating most commonly, appearing in up to 67% of cases as stated in the NIH report. (diseaselandscape.com)
- Owing to the region's extreme gene density, the multiplicity of disease-associated alleles, strong associations between alleles, limited genotyping capability, and inadequate statistical approaches and sample sizes, which, and how many, loci within the MHC determine susceptibility remains unclear. (ox.ac.uk)
- AIH usually develops in individuals with a genetic background mainly consisting of some risk alleles of the major histocompatibility complex (HLA). (wjgnet.com)
- These three associated variants within the BTNL2 gene were neither in linkage disequilibrium with each other nor correlated with the SNPs tagging the human leukocyte antigen (HLA)-DRB1*1502 and HLA-DRB1*0301 alleles. (ox.ac.uk)
- We imputed HLA alleles in an independent data set from the British 1958 Birth Cohort (N = 918) with gold standard four-digit HLA types and SNPs genotyped using the Affymetrix GeneChip 500 K and Illumina Immunochip microarrays. (nih.gov)
- The association of T1D with alleles at HLA loci, especially the HLA class II genes DR and DQ, is well-established. (medcraveonline.com)
- Many SNPs in the major histocompatibility complex (MHC) region, most often those tagging the shared epitope (SE) alleles of HLA-DRB1, are among risk SNPs for RA. (snpedia.com)
- Researchers have identified hundreds of different versions (alleles) of the HLA-DQA1 gene, each of which is given a particular number (such as HLA-DQA1*05:01 ). (medlineplus.gov)
- Here we present 4.25 Mb of the human haplotype QBL (HLA-A26-B18-Cw5-DR3-DQ2) and compare it with the MHC reference haplotype and with a second haplotype, COX (HLA-A1-B8-Cw7-DR3-DQ2), that shares the same HLA-DRB1, -DQA1, and -DQB1 alleles. (ox.ac.uk)
- In this work, we analyzed the binding affinities of mutated peptides of Omicron strain variants BA.1-BA.5 and the worldwide prevalent HLA alleles. (bvsalud.org)
- In this regard, global efforts are currently underway to study possible correlations between HLA alleles with the occurrence and severity of SARS-CoV-2 infection. (bvsalud.org)
- Specifically, this study examined the possible association between specific HLA alleles and susceptibility to SARS-CoV-2 in a population from the United Arab Emirates (UAE). (bvsalud.org)
- HLA alleles and supertypes were compared between hospitalized and non-hospitalized subjects. (bvsalud.org)
- Statistical significance was observed between certain HLA alleles and supertypes and the severity of the infection. (bvsalud.org)
- Specifically, alleles HLA-B*51:01 and HLA-A*26:01 showed a negative association (suggestive of protection), whilst genotypes HLA-A*03:01, HLA-DRB1*15:01, and supertype B44 showed a positive association (suggestive of predisposition) to COVID-19 severity. (bvsalud.org)
Loci11
- Several susceptibility loci for classical Hodgkin lymphoma have been reported. (ox.ac.uk)
- Additionally, independent loci within the HLA region are observed for nodular sclerosis Hodgkin lymphoma (rs9269081, HLA-DPB1*03:01, Val86 in HLA-DRB1) and mixed cellularity Hodgkin lymphoma (rs1633096, rs13196329, Val86 in HLA-DRB1). (ox.ac.uk)
- More than 200 susceptibility loci have been identified in populations of predominantly European ancestry, but few loci have been associated with IBD in other ethnicities. (njit.edu)
- One such determinant is the potential involvement of genetic susceptibility loci to asthma after viral bronchiolitis, a critical area that is just beginning to be evaluated. (atsjournals.org)
- This study described the genetic patterns of HLA-A, -B, and -DRB1 loci in patients from Beijing who survived SARS, and examined whether an association between HLA genes and susceptibility/resistance to SARS exists. (blood-genomics.com)
- Other loci with smaller and/or rarer effects might also be involved, but to find these, future searches must take into account both the HLA class II and class I genes and use even larger samples. (ox.ac.uk)
- A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region. (uchicago.edu)
- Several genes, including CR1, PICALM, ABCA7, HLA-DRB5/HLA-DRB1, and SLC24A4/RIN3 have been identified as AD susceptibility loci by GWAS, and are associated with inflammation, immune response, lipid metabolism and intracellular trafficking [ 5 ]. (biomedcentral.com)
- Long-range linkage disequilibrium between HLA loci and SNP markers across the major histocompatibility complex (MHC) region offers an alternative approach through imputation to interrogate HLA variation in existing GWAS data sets. (nih.gov)
- More than 60 genes have been identified to affect the risk of T1D, with the HLA loci having the greatest impact on susceptibility. (medcraveonline.com)
- We have defined the complete gene, splice variant, and sequence variation contents of all three haplotypes, comprising over 259 annotated loci and over 20,000 single nucleotide polymorphisms (SNPs). (ox.ac.uk)
Allele14
- HLA-DRB1*13:01 allele in the genetic susceptibility to colorectal carcinoma. (cdc.gov)
- HLA-DRB1 allele polymorphism and nasopharyngeal carcinoma risk: a meta-analysis. (cdc.gov)
- The HLA-DRB1 allele polymorphisms and nasopharyngeal carcinoma. (cdc.gov)
- Relationship between HLA-DRB1 allele polymorphisms and familial aggregations of hepatocellular carcinoma. (cdc.gov)
- A meta-analysis of 13 studies suggested that carriage of the HLA-DRB1*07 allele increases susceptibility to ARF/rheumatic heart disease, while carriage of the HLA-DRB1*15 allele protects against it. (medscape.com)
- 0.0001), and the frequency of the HLA-DRB1*15 allele was significantly lower (OR = 0.60, P = 0.03). (medscape.com)
- TLR2 2258G allele may provide protective effects against PTB susceptibility, particularly among Asians, whereas TLR2 T597C polymorphism might not be associated with PTB susceptibility. (cdc.gov)
- whereas that of DRB1*07 allele was lower (2.78% vs 7.75%,OR = 0.340, P = 0.046). (wanfangdata.com.cn)
- The frequency of HLA-DRB1* 14allele was higher in 11 responders to IFN compared with 24 non-responders (18.18% vs2.08%, OR = 10.444,P = 0.031), whereas that of DQB1*07 allele was inverse (9.09% vs 37.50%, OR = 0.167, P= 0.021).CONCLUSION: The polymorphism of HLA class Ⅱ may influence the susceptibility to HBV infection and the response to IFN in studied CHB patients. (wanfangdata.com.cn)
- We observed similar proportions of HLA DRB1*1302 carriers in E-P positive cases and controls, but interestingly, this allele was not found in AA cases (p = 0.03, Fisher exact test). (biomedcentral.com)
- An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes. (uchicago.edu)
- Results: No significant differences in the genotype and allele frequencies between HSP patients and controls were observed when the CSK rs34933034, CSK rs1378942, PTPN22 rs2476601 (R620W) and PTPN22 rs33996649 (R263Q) polymorphisms were analyzed independently. (unican.es)
- At the same time, there were novel potential mutant epitopes (binding affinity less than 50 nM) in case of HLA-A*32:01 allele. (bvsalud.org)
- The characterization of HLA allele frequency in the population can play an important role in determining whether HLA antigens contribute to viral susceptibility. (bvsalud.org)
SNPs5
- Results We detected SNPs at HLA-DRB1, and African-specific SNPs at ZNF649 and LSAMP, with associations of genome-wide significance for UC. (njit.edu)
- We developed a novel constrained deep learning neural network which utilizes SNPs (single nucleotide polymorphisms) and microarray data from ADNI (Alzheimer's Disease Neuroimaging Initiative) to predict the disease status of participants, i.e. (biomedcentral.com)
- The SHAP scores show that SNPs in PRKCZ, PLCB1 and ITPR2 as well as expression of HLA-DQB1, EIF1AY, HLA-DQA1, and ZFP57 have more impact on model predictions. (biomedcentral.com)
- Disease-related genes are commonly identified using genome-wide association studies (GWAS) [ 5 ], in which several million single nucleotide polymorphisms (SNPs) are tested for association with a specific trait or disease. (biomedcentral.com)
- In this study using 58 single nucleotide polymorphisms (SNPs) with 616 UC cases, there was significant association with SNP rs2294881 of the (butyrophilin-like 2) BTNL2 gene with odds ratio (OR) = 2.80, confidence interval (CI) = 1.62-4.84 and P = 5.69 x 10(-4) (P(Bonferroni) = 3.3 x 10(-2)) and replication of SNP rs9268480. (ox.ac.uk)
Antigens2
- No significant association with class-I human leukocyte antigens (HLAs) has been found, but an increase in class-II HLA antigens DR2 and DR4 has been found in black and white patients, respectively. (medscape.com)
- The class I and class II Human Leucocyte Antigens (HLA) are an integral part of the host adaptive immune system against viral infections. (bvsalud.org)
Gene polymorphisms4
- The correlation between HLA-DRB1 and HLA-DQB1 gene polymorphisms and cytokines in HPV16 infected women with advanced cervical cancer. (cdc.gov)
- Association of HLA-DRB1 gene polymorphisms with hepatocellular carcinoma risk: a meta-analysis. (cdc.gov)
- To determine the effects of cytokine gene polymorphisms in the pathogenesis of T1D, high risk interferon-gamma (IFN-γ), interleukin-6 (IL-6) as well as transforming growth factor β (TGF-β) gene polymorphisms were considered in HLA DRDQ fixed patients with T1D. (medcraveonline.com)
- A number of cytokine gene polymorphisms have been shown to be important for the development of T1D both at the level of the immune system and at the level of the target β-cells. (medcraveonline.com)
Haplotypes7
- OBJECTIVE- HLA-DRB1* 03 -DQB1* 0201 /DRB1* 04 -DQB1* 0302 ( DR3/4-DQ8 ) siblings who share both major histocompatibility complex (MHC) haplotypes identical-by-descent with their proband siblings have a higher risk for type 1A diabetes than DR3/4-DQ8 siblings who do not share both MHC haplotypes identical-by-descent. (diabetesjournals.org)
- In keeping with this observation, no significant differences were found when we assessed these polymorphisms combined conforming haplotypes. (unican.es)
- At least two specific combinations of HLA gene variants (HLA haplotypes) have been found to increase the risk of developing celiac disease, a disorder in which inflammation damages the intestinal tract and other organs and tissues. (medlineplus.gov)
- One of these haplotypes, known as DQ2, is composed of the protein produced from HLA-DQA1 gene variants known as HLA-DQA1*05:01 or HLA-DQA1*05:05 bound to the protein produced from HLA-DQB1 gene variants known as HLA-DQB1*02:01 or HLA-DQB1*02:02 . (medlineplus.gov)
- Type 1 diabetes risk is most increased by two HLA haplotypes involving variations of the HLA-DQA1 and HLA-DQB1 genes and another HLA gene called HLA-DRB1 . (medlineplus.gov)
- Other HLA haplotypes only mildly increase the risk of type 1 diabetes, while some haplotypes seem to protect against developing this condition. (medlineplus.gov)
- Analysis of the two DR3 haplotypes allowed delineation of the shared sequence between two HLA class II-related haplotypes differing in disease associations and the identification of at least one of the sites that mediated the original recombination event. (ox.ac.uk)
Nucleotide4
- Meta-analyses of candidate gene studies suggest that the TGF-β1 [rs1800469] and IL-1β [rs2853550] single-nucleotide polymorphisms contribute to susceptibility to rheumatic heart disease. (medscape.com)
- Association of single nucleotide polymorphisms (4G/5G) of plasminogen activator inhibitor-1 and the risk factors for placenta-related obstetric complications. (cdc.gov)
- Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences. (uchicago.edu)
- Two well-known CSK (CSK rs34933034 and CSK rs1378942) and two functional PTPN22 (PTPN22 rs2476601 (R620W) and PTPN22 rs33996649 (R263Q)) polymorphisms, previously associated with autoimmunity, were genotyped with TaqMan single nucleotide polymorphism (SNP) genotyping assays. (unican.es)
Genome-Wide1
- Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility. (ox.ac.uk)
Haplotype6
- Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1. (uchicago.edu)
- HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease. (uchicago.edu)
- PMID 17216583 ] The functional haplotype of peptidylarginine deiminase IV (S55G, A82V and A112G) associated with susceptibility to rheumatoid arthritis dominates apoptosis of acute T leukemia Jurkat cells. (snpedia.com)
- The other haplotype, known as DQ8, is composed of the protein produced from HLA-DQA1 gene variants known as HLA-DQA1*03:01 or HLA-DQA1*03:02 bound to the protein produced from the HLA-DQB1 gene variant known as HLA-DQB1*03:02 . (medlineplus.gov)
- One haplotype, written as DRB1*03:01-DQA1*05:01-DQB1*02 , is called DR3. (medlineplus.gov)
- The other haplotype, written as DRB1*04:01/02/04/05/08-DQA1*03:01-DQB1*02 , is called DR4. (medlineplus.gov)
Rheumatoid arthritis2
- HLA-DRB1 and CD2AP gene were identified to be among the susceptibility genes of KBD, thus supporting the role of the autoimmune response in KBD and the possibility of shared etiology between osteoarthritis, rheumatoid arthritis, and KBD. (escholarship.org)
- HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis. (uchicago.edu)
PTPN221
- Abstract: Introduction: To determine whether the PTPN22 (protein tyrosine phosphatase nonreceptor 22)/CSK (c-src tyrosine kinase) pathway is implicated in the susceptibility and clinical heterogeneity of Henoch-Schönlein purpura (HSP) in the largest series of Caucasian HSP patients ever assessed for genetic studies. (unican.es)
Exon1
- The present study aimed at detecting the association of ovine major histocompatibility complex class II (Ovar II) DRB 1 gene second exon and susceptibility or resistance to hydatidosis in three sheep breeds of Sinkiang. (parasite-journal.org)
Association7
- There is an association of polymorphisms of the calcium channel alpha1-subunit gene with thyrotoxic periodic paralysis. (medscape.com)
- In the validation stage, single locus effects revealed that two of these polymorphisms (rs7745040 and rs9275295) in the human leukocyte antigen (HLA)-DRB1 gene and one polymorphism (rs9473132) in CD2-associated protein (CD2AP) gene have a significant statistical association with KBD. (escholarship.org)
- Our study suggests that HLA polymorphisms were unlikely to have contributed significantly to either the susceptibility or resistance to the SARS-Cov infection in patients who survived SARS in the Northern Chinese population, thus leaving an open question for future studies into a possible association HLA class Ⅰ and class Ⅱ genes with SARS in patients who were unable to survive the infection. (blood-genomics.com)
- Our results suggest that the association between HLA polymorphism and risk of ICC might be influenced by the distribution of HPV-16 variants. (biomedcentral.com)
- In type 1 diabetes the major genetic susceptibility determinants have been mapped to the MHC class II genes HLA-DQB1 and HLA-DRB1 (refs 1-3), but these genes cannot completely explain the association between type 1 diabetes and the MHC region. (ox.ac.uk)
- Linkage in families and association in population case-control investigations have clearly shown that genes within the major histocompatibility complex region on chromosome 6p are relevant to the susceptibility and pathogenesis of ulcerative colitis (UC) and Crohn's disease. (ox.ac.uk)
- This indicated a strong association between these patterns and hydatidosis susceptibility. (parasite-journal.org)
Pathogenesis2
- Effect of the CYBA C242T Polymorphism on Preeclampsia Pathogenesis in the Chinese Population. (cdc.gov)
- In this pilot study, we determined that there may be critical networking among different cytokines and HLA which may play a role in the pathogenesis of T1D. (medcraveonline.com)
Type 1 diabet3
- Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. (ox.ac.uk)
- Taken together with previous studies, we conclude that MHC-class-I-mediated events, principally involving HLA-B*39, contribute to the aetiology of type 1 diabetes. (ox.ac.uk)
- Combinations of variations in the HLA-DQA1 gene and other HLA genes affect the risk of type 1 diabetes. (medlineplus.gov)
Binding protein1
Amino acid1
- For amino acid polymorphisms within HLA genes, we achieve 98.6% and 99.3% accuracy using the Affymetrix GeneChip 500 K and Illumina Immunochip, respectively. (nih.gov)
Relationship3
- A meta-analysis was conducted to investigate the relationship between TLR2 G2258A and T597C polymorphisms with PTB susceptibility. (cdc.gov)
- A systematic search was performed for published studies on the relationship between TLR2 polymorphisms and PTB susceptibility. (cdc.gov)
- Relationship of myostatin gene polymorphism with some growth traits of common carp Cyprinus carpio L. (emarefa.net)
Cytokines1
- However, a larger scale case control study is required to confirm these findings and to determine the functionality of cytokines and the high-risk HLA patients. (medcraveonline.com)
Chromosome1
- The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more common diseases than any other region of the human genome, including almost all disorders classified as autoimmune. (ox.ac.uk)
Infection3
- Therefore, no apparent defects in innate susceptibility based on the degree of bacterial proliferation and time to death were found for IL-21-deficient compared with control mice after high-dose L. monocytogenes infection. (atm-signaling.com)
- selleck chemicals llc In similar experiments, the susceptibility of IL-21-deficient mice was also enumerated after infection with reduced L. monocytogenes inocula (103 CFUs) to more precisely characterize the potential requirement for IL-21 in innate host defence. (atm-signaling.com)
- By clarifying the roles of both host- (genetic) and virus- (environment) specific factors that contribute to the frequency and severity of viral LRTI, it may be possible to determine if severe LRTIs cause asthma, or if asthma susceptibility predisposes patients to severe LRTI in response to viral infection. (atsjournals.org)
Genotypes1
- Thus, both the occurrence and the prognosis of glioblastoma multiforme could be associated with specific but different HLA genotypes. (aacrjournals.org)
Antigen5
- Human leukocyte antigen-G 14 bp insertion/deletion polymorphism contributes to preeclampsia risk in Asian population: A systematic review and meta?analysis. (cdc.gov)
- We examined the relationships of human leukocyte antigen (HLA) and related polymorphisms to glioblastoma multiforme in adult Caucasians (non-Hispanic Whites) from the San Francisco Bay area. (aacrjournals.org)
- DNA sequence variation within human leukocyte antigen (HLA) genes mediate susceptibility to a wide range of human diseases. (nih.gov)
- The HLA-DQA1 gene is part of a family of genes called the human leukocyte antigen (HLA) complex. (medlineplus.gov)
- INTRODUCTION: In this study, we evaluated whether SARS-CoV-2 mRNA vaccines induce anti-human leukocyte antigen (HLA) antibodies and anti- ABO blood type antibodies (ABOAb) in kidney transplant recipients (KTRs). (bvsalud.org)
Antibody1
- CONCLUSIONS: The SARS-CoV-2 mRNA vaccine did not induce anti-HLA antibody or ABOAb production in KTRs. (bvsalud.org)
Genes associated1
- Recent advances have been made in the of host factors, polymorphisms, and candidate genes associated characterization of the immune response to low-molecular- with occupational asthma may improve our understanding of weight agents. (cdc.gov)
Class3
- HLA class II polymorphisms are also associated with genetic susceptibility to ICC. (biomedcentral.com)
- The HLA-DQA1 gene belongs to a group of MHC genes called MHC class II. (medlineplus.gov)
- The protein produced from the HLA-DQA1 gene attaches (binds) to the protein produced from another MHC class II gene, HLA-DQB1 . (medlineplus.gov)
Human1
- The HLA complex is the human version of the major histocompatibility complex (MHC), a gene family that occurs in many species. (medlineplus.gov)
Unclear1
- Although the inciting bacterial agent is well known, susceptibility factors remain unclear. (medscape.com)
Viral2
- We showed that, for all five viral variants, mutations cause a significant reduction in the number of tightly binding peptides for HLA-B*07:02 and HLA-C*01:02 molecules. (bvsalud.org)
- Interestingly, mutations caused multidirectional effect on the binding affinities of the viral peptides and HLA-DRB1*03:01. (bvsalud.org)
Risk5
- Genetic variations in STAT4,C2,HLA-DRB1 and HLA-DQ associated with risk of hepatitis B virus-related liver cirrhosis. (cdc.gov)
- HLA-A*26-A*30 and HLA-DRB1*10 could be predictors of nasopharyngeal carcinoma risk in high-risk Tunisian families. (cdc.gov)
- The eNOS-G894T genetic polymorphism and risk of preeclampsia: A case-control study, an updated meta-analysis, and a bioinformatic assay. (cdc.gov)
- While APOE ε4 has been established as a significant risk factor for AD susceptibility, AD is considered a complex trait in which a combination of genetic and environmental factors influences disease pathology [ 5 ]. (biomedcentral.com)
- therefore, HLA is not an adequate measure to evaluate the risk of T1D. (medcraveonline.com)
Disease2
- To identify and investigate the susceptibility genes of Kashin-Beck disease (KBD) in Chinese population. (escholarship.org)
- Advancement in identification of MHC genes that confer susceptibility to disease requires greater knowledge of sequence variation across the complex. (ox.ac.uk)
Variants1
- We characterized HPV-16 variants by PCR in 107 ICC cases, which were typed for HLA-DQA1 , DRB1 and DQB1 genes and compared to 257 controls. (biomedcentral.com)
Immune System2
- The HLA-DQA1 gene provides instructions for making a protein that plays a critical role in the immune system. (medlineplus.gov)
- The HLA complex helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria. (medlineplus.gov)
Clinical1
- The results support the potential use of HLA testing to differentiate between patients who require specific clinical management strategies. (bvsalud.org)
Arthritis1
- Arthritis susceptibility genes were sought by analysis of differential gene expression between pristane-induced arthritis (PIA)-susceptible DA rats and PIA-resistant E3 rats. (biomedcentral.com)
Associations2
- Publications regarding the associations of toll-like receptor 2 (TLR2) G2258A and T597C polymorphisms with pulmonary tuberculosis (PTB) susceptibility are inconsistent. (cdc.gov)
- The associations of T597C polymorphism with PTB susceptibility, in the ethnic-specific analyses, were still not significant. (cdc.gov)
Suggests1
- [ 5 ] Evidence suggests that elevated immune-complex levels in blood samples from patients with ARF are associated with HLA-B5. (medscape.com)