• DR7:DQA1*0201:DQB1*0202 is associated with Graves' disease. (wikipedia.org)
  • The A29-Cw16-B44-DR7-DQ2 haplotype is in strong linkage disequilibrium particularly in Northwestern Europe. (wikipedia.org)
  • This haplotype is found in Korea but not Japan, in fact Japan is an antinode of DR7. (wikipedia.org)
  • There is the possibility that this haplotype is a recent (Holocene) arrival from Africa or the Middle East to Central Asia as this best explains the alleles within the haplotype. (wikipedia.org)
  • The most frequent A-B-DR-DQ haplotypes in Korea are found at ~3/4 the Korean frequencies in Japan, except A33-Cw7-B44-DR7-DQ2, which indicates that DR7 likely spread into Korea after the Japan's Yayoi migration when most of the Korean contribution occurred. (wikipedia.org)
  • HLA class II polymorphism in cystic fibrosis. (nih.gov)
  • The analysis of genetic factors other than CFTR may help our understanding of genotype-phenotype relationships in CF. As human leukocyte antigen (HLA) class II polymorphism has been associated with a number of diseases including autoimmune and inflammatory diseases, asthma, and allergy, we investigated the possibility that HLA polymorphism contributes to CF-associated pulmonary inflammation. (nih.gov)
  • The aim of this study was to find out the association of HLA Classes I and II genes with chronic periodontitis in East Indian population. (nih.gov)