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  • tumor
  • In addition, crocin (6.25, 25 mg/kg) inhibited the tumor weight and size of HL-60 xenografts in nude mice, inhibited Bcl-2 expression, and increased Bax expression in xenografts. (hindawi.com)
  • Humans
  • The human genome may encode over 1000 miRNAs, which are abundant in many mammalian cell types and appear to target about 60% of the genes of humans and other mammals. (wikipedia.org)
  • Tissues
  • miRNA research revealed different sets of miRNAs expressed in different cell types and tissues and multiple roles for miRNAs in plant and animal development and in many other biological processes. (wikipedia.org)
  • Culture
  • While the majority of miRNAs are located within the cell, some miRNAs, commonly known as circulating miRNAs or extracellular miRNAs, have also been found in extracellular environment, including various biological fluids and cell culture media. (wikipedia.org)
  • treatment
  • Following D(3) treatment, the G1-enriched small cells expressed CD11b slightly faster than unsynchronized cultures or fractions dominated by late G1 cells and/or S phase cells. (biomedsearch.com)
  • effects
  • However, the effects of crocin on HL-60 cells in vivo have not been evaluated. (hindawi.com)
  • However, the effects of crocin on HL-60 cells in vivo have not been evaluated, and the mechanism responsible for the antileukemia effects of saffron remains elusive. (hindawi.com)
  • majority
  • It is also characterized by a low number of platelets, a low number of white blood cells, and elevated serum transaminase levels in the majority of infected patients. (wikipedia.org)