Histological lung cancer adenocarcinoma. Medical search. Frequent questions

The most common paraneoplastic syndromes associated with adenocarcinoma of the lung are described below: Hypercalcemia of malignancy is more common in squamous cell carcinoma of the lung, but can occur in adenocarcinoma as well. (wikipedia.org)
4 As the primary type of lung cancer, non-small cell lung cancer (NSCLC) exhibits multiple histological types, such as bronchoalveolar carcinoma, large cell carcinoma, squamous cell carcinoma, and adenocarcinoma. (dovepress.com)
We conclude that pulmonary exposure to SWCNT favors the formation of a niche that supports ingrowth of lung carcinoma in vivo via activation of TGFβ production by SWCNT-attracted and -presensitized MDSC. (cdc.gov)
In 2007, in Australia, lung cancer was the fourth most commonly diagnosed cancer in both males and females (excluding basal and squamous cell carcinoma of the skin), with a total of 9,703 diagnosed ( AIHW & Cancer Australia 2011 ).Lung cancer is the leading cause of cancer deaths for both sexes. (copdx.org.au)
Cox proportional hazards models were used to estimate HRs relating air pollutant exposures to all-cause mortality overall and stratified by stage (localised only, regional and distant site) and histology (squamous cell carcinoma, adenocarcinoma, small cell carcinoma, large cell carcinoma and others) at diagnosis, adjusting for potential individual and area-level confounders. (bmj.com)
Enrollment required patients with a tumor ≤ 2 cm in diameter, diagnosed or suspected as a clinical T1N0M0 carcinoma in the lung periphery based on a CT scan. (iaslc.org)
These results indicate that higher BMI may increase the risk of certain types of lung cancer, in particular SQ and SC carcinoma. (liverpool.ac.uk)
HPV DNA is found in two of 18 cases of squamous cell carcinoma (II %), in one of 4 cases of adenocarcinoma, and in two of 7 cases of neuro-endocrin cancers. (coek.info)
So HPV might playa role as promoter in carcinogenesis of any types of lung carcinoma, although at a low frequency. (coek.info)
Histologically, NSCLC is divided into adenocarcinoma, squamous cell carcinoma (SCC) (see the image below), and large cell carcinoma. (medscape.com)
In India, lung carcinoma is the fifth-most common tumor and second-most common tumor in the males as per the Indian Council of Medical Research registry of 2002. (ijpmonline.org)
Hence, our objective was to detect association of cancer stem cell (CSC) marker aldehyde dehydrogenase 1 (ALDH1) with clinicopathological profile in lung carcinoma patients. (ijpmonline.org)
Strong ALDH1 expression correlates with higher stage of lung carcinoma making it a prognostic marker needing in-depth study. (ijpmonline.org)
however, a worldwide increase has been seen since then in deaths caused by Lung carcinoma leading to increased age-adjusted death rates. (ijpmonline.org)
In 1985, Lung carcinoma became the leading cause of cancer deaths in women and now causes approximately twice as many deaths as breast cancer. (ijpmonline.org)
The most common histological type of lung cancer was squamous cell carcinoma followed by adenocarcinoma. (ac.ir)
Conclusion: Our results showed a higher prevalence of lung cancer in males, age group of 46-65, smokers and moderate and low socioeconomic classes while the most common type was squamous cell carcinoma. (ac.ir)
Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)
As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
He had recently been diagnosed with adenocarcinoma in the right upper lobe, with a poorly differentiated carcinoma favoring squamous cell cancer based on bronchoalveolar lavage of the right lower lobe for which treatment was started. (biomedcentral.com)
We identified a unique case of triple SLC, including adenocarcinoma, squamous cell carcinoma, and mixed small and large cell neuroendocrine carcinoma, which has poor prognostic implications. (biomedcentral.com)
Despite the fact that, worldwide, adenocarcinoma has increased incidence, in our study squamous cell carcinoma was the main histological subtype. (umbalk.org)
The most common histological change is the switch from adenocarcinoma (AdenoCa) to small cell carcinoma (SCC) against to tyrosine kinase inhibitors (TKI). (e-crt.org)
Telomerase, undetectable in normal somatic cells, plays a critical role in carcinogenesis of the majority of human tumors including lung carcinoma. (edu.pl)
A significant difference in hTERT expression between two types of histopathological pattern (adenocarcinoma and squamous cell carcinoma) was detected (p=0.01). (edu.pl)
The association was observed for all major histological types, being the strongest for small-cell type carcinoma, followed by squamous-cell type and the lowest for adenocarcinoma. (ox.ac.uk)
Cases of squamous cell carcinoma (SCC) amounted to 11.9% and 0.88% had both adenocarcinoma and SCC. (bangkokmedjournal.com)
Volume-rendered 3-dimensional CT scan shows a metastatic mass in the trachea from squamous cell carcinoma of the lung. (medscape.com)
By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
[ 3 , 4 ] The term "pseudomesotheliomatous carcinoma" was first applied by Harwood and colleagues in 1976 to 6 cases of peripheral lung adenocarcinoma that closely mimicked mesothelioma. (medscape.com)
Among males, an estimated 560 108 (39%) of all lung cancer cases were adenocarcinoma, 351 807 (25%) were squamous cell carcinoma, 163 862 (11%) were small-cell carcinoma, and 115 322 (8%) were large-cell carcinoma. (who.int)
Among females, an estimated 440 510 (57%) of all lung cancer cases were adenocarcinoma, 91 070 (12%) were squamous cell carcinoma, 68 224 (9%) were small-cell carcinoma, and 49 246 (6%) were large-cell carcinoma. (who.int)
among females, the incidence rates of adenocarcinoma exceeded those of squamous cell carcinoma in all 185 countries and territories studied. (who.int)
2 Diagnosis of small cell (neuroendocrine) or mucinous adenocarcinoma of cervical cancer (ie, mucinous NOS, intestinal type, signet ring cell type, invasive stratified mucin producing carcinoma and gastric type) based on 2020 WHO classification of cervical cancer. (who.int)

Treatment of this lung cancer is based upon the specific subtype and the extent of spread from the primary tumor. (wikipedia.org)
Adenocarcinoma is the most common histological subtype, accounting for about half of all lung cancers [ 1 ]. (hindawi.com)
Our observations indicate that induction of NY-ESO-I autoantibodies depends on the histological subtype within a given tumor entity. (nih.gov)
Results were stratified by histological subtype, smoking status and sex. (liverpool.ac.uk)
Invasive mucinous adenocarcinoma (IMA) of the lung is a distinct histological subtype with unique clinical and pathological features. (figshare.com)

This is caused by compression of vasculature by the lung tumor that restricts blood return from the upper body. (wikipedia.org)
Clinical Implications and Molecular Characterization of Drebrin-Positive, Tumor-Infiltrating Exhausted T Cells in Lung Cancer. (go.jp)
However, the lung tumor spread to the small intestine, causing intestinal obstruction. (spandidos-publications.com)
These vesicles are constitutively secreted by all cell types and EVs released from cancer cells can functionally alter recipient cells by reprogramming them to become active contributors to tumor growth, metastasis, and immunosuppression ( 10 ). (frontiersin.org)
Understanding the mechanism underlying the role of tumor stroma, especially cancer-associated fibroblasts (CAFs), during chemoresistance would significantly contribute to the clinical application of chemotherapy agents. (dovepress.com)
Cancer-associated fibroblasts (CAFs) have been demonstrated to be essential stromal components in the tumor microenvironment, regulating cancer cell growth, migration, invasion, and chemo-response through various mechanisms. (dovepress.com)
11 Chemoresistance, either acquired or intrinsic, is associated with a complicated and multifactorial process, including decreases of intracellular drugs, changes of drug targets, aberrant regulation of cell survival or death, and crosstalks between tumor microenvironment and cancer cells. (dovepress.com)
MDSC and TGFβ are required for facilitation of tumor growth in the lungs of mice exposed to carbon nanotube s. (cdc.gov)
This suggests the emergence of new etiological factors and mechanisms including those defining the lung microenvironment, promoting tumor growth. (cdc.gov)
Assuming that the lung is the main portal of entry for broadly used nanomaterial s and their established proinflammatory propensities, we hypothesized that nanomaterial s may contribute to changes facilitating tumor growth. (cdc.gov)
Here, we report that an acute exposure to single-walled carbon nanotube s (SWCNT) induces recruitment and accumulation of lung-associated myeloid-derived suppressor cells (MDSC) and MDSC-derived production of TGFβ, resulting in upregulated tumor burden in the lung. (cdc.gov)
Plenty of research had reported that the tumor immune microenvironment (TIME) impacts cancer progression and metastases, as well as affects patient prognoses and outcomes [ 6 , 7 ], which emphasizes the important role of immune cells, vital components of the tumor microenvironment, impacting on patient survival and tumor progression [ 8 , 9 ]. (aging-us.com)
Cancer occurrence was ascertained through linkages with regional tumor registries. (biomedcentral.com)
Lasp1 (LIM and SH3 domain protein 1) promotes tumor proliferation and invasion in multiple cancer entities including non-small cell lung cancer (NSCLC). (oncotarget.com)
Previous studies had confirmed that Lasp1 was significantly overexpressed in multiple malignant tumors including non-small-cell lung cancer (NSCLC) and enhanced tumor proliferation, invasion and metastasis [ 7 - 13 ]. (oncotarget.com)
DM: maximum tumor diameter on mediastinal settings, DL: maximum tumor diameter on lung settings). (iaslc.org)
Increased miR-27a expression was also detected in tumor tissues sampled from lung adenocarcinoma patients treated with cisplatin-based chemotherapy and was proved to be correlated with low expression of RKIP, decreased sensitivity to cisplatin, and poor prognosis. (biomedcentral.com)
Chapter 32 Gastrointestinal Cancers DIAGNOSIS TREATMENT DIAGNOSITC IMAGING MEDICATIONS CT scan, MRI, labeled somatostatin receptor-based diagnostic imaging ▪ Localization, TNM staging ▪ Presence of hepatic lesions SURGERY Endoscopy with biopsy ▪ Tumor visualization ▪ Histopathological analysis, grading ▪ Somatostatin analogues suppress tumor proliferation, decrease symptoms ▪ Surgical removal of tumor LAB RESULTS ▪ 5-hydroxyindoleacetic acid, chromogranin Figure 32.2 Gross pathology of carcinoid tumor of the terminal ileum. (osmosis.org)
Figure 32.1 Histological appearance of a carcinoid tumor of the lung. (osmosis.org)
To build a preclinical platform that covers this broad disease spectrum, we obtained lung cancer specimens from multiple sources, including sputum and circulating tumor cells, and generated a living biobank consisting of 43 lines of patient-derived lung cancer organoids. (elsevierpure.com)
The TNM (tumor-node-metastasis) staging system from the American Joint Committee for Cancer Staging and End Results Reporting is used for all lung carcinomas except small-cell lung cancer. (medscape.com)
The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of the TNM Classification of Lung Cancer. (nih.gov)
There was no significant association between hTERT expression in the tumor tissue and age, gender, histological type of the tumor, grading or clinical stage. (edu.pl)
hTERT mRNA detection by QRT-PCR in tumor and corresponding cancer-free tissues can be used as a diagnostic marker in patients with NSCLC, but seems not to be a prognostic factor. (edu.pl)
Lung cancer is a malignant tumor starting point of glandular bronchial epithelium. (about-health-problems.com)
Lung cancer has become the most common malignant tumor in China with the highest morbidity and mortality, of which non-small cell lung cancer (NSCLC) accounts for 80% [ 1 , 2 ]. (biomedcentral.com)
Background Lung tumor may be the most lethal and occurrence type of tumor, with late medical diagnosis as a significant determinant of its poor prognosis. (mindunwindart.com)
CSF-1 has already been studied as a potential target of aimed therapies to boost response to anti-angiogenic therapies and immunotherapies in tumor, but this is actually the first research to judge the relationship between serum degrees of CSF-1 and Ang-2 in lung tumor sufferers. (mindunwindart.com)
This research shows that raised CSF-1 amounts are correlated with an elevated probability of the current presence of lung tumor. (mindunwindart.com)
The outcomes shown within this scholarly research may open up the entranceway to a fresh eyesight of lung tumor screening process, with the look of protocols that may anticipate with higher precision which band of individuals ought to be studied with an increase of attention. (mindunwindart.com)
As examples of this we have a subgroup of patients with lung adenocarcinoma, who are carriers of a mutation in the receptor gene of the epidermal growth factor (EGFR), for whom there are drugs capable of blocking the mutation and, consequently, of inhibiting the growth of the tumor. (hospiten.com)
When the primary tumor invades the venous system, tumor cells embolize to the lungs through the pulmonary or bronchial arteries. (medscape.com)
Diagnostic value of exfoliated tumor cells combined with DNA methylation in bronchoalveolar lavage fluid for lung cancer. (cdc.gov)
Regarding the histological type of tumor, there was a wide variation between studies. (bvsalud.org)
To identify operable lung cancer patients with risk for metastatic relapse we search for new prognostic biomarkers based on analysis of genome-wide gene expression data and conventional protein marker validation based on analysis of primary tumor tissue. (lu.se)
By analysis of patient specific alterations in circulating tumor DNA in blood samples we aim to establish blood-based assays for early detection of lung cancer, treatment monitoring, and early detection of relapse in the primary and advanced setting. (lu.se)

It is classified as one of several non-small cell lung cancers (NSCLC), to distinguish it from small cell lung cancer which has a different behavior and prognosis. (wikipedia.org)
Screening in high-risk smokers results in a reduction in lung cancer mortality, however, screening efforts are primarily focused on non-small cell lung cancer (NSCLC). (frontiersin.org)
Lung cancers are histologically classified as Small Cell Lung Cancer (SCLC) or Non-Small Cell Lung Cancer (NSCLC). (frontiersin.org)
Chemoresistance is a significant barrier to the treatment and management of non-small cell lung cancer (NSCLC). (dovepress.com)
Targeted therapy with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) is the standard first-line treatment for advanced EGFR -mutated non-small cell lung cancer (NSCLC). (frontiersin.org)
BACKGROUND: Non-small cell lung cancer (NSCLC) is heterogeneous. (bvsalud.org)
METHODS: Here, we downloaded the NSCLC expression profiles from The Cancer Genome Atlas and the Gene Expression Omnibus databases. (bvsalud.org)
Lobectomy remains the standard treatment for early-stage non-small cell lung cancer (NSCLC).In practice, however, sublobar resection has been selectively offered for patients with clinical Stage IA NSCLC as curative treatment. (iaslc.org)
To seek optimal surgical procedure for early stage lung cancer, we carried out retrospective analyses of 2122 patients who had undergone limited resection for c-T1N0M0 NSCLC from 26 institutions of Japanese association for chest surgery. (iaslc.org)
Non-small cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancers. (medscape.com)
Because most lung cancers cannot be cured with currently available therapeutic modalities, the appropriate application of skilled palliative care is an important part of the treatment of patients with NSCLC. (medscape.com)
It has been seen that ALDH1 expression in non-small cell lung cancer (NSCLC) and the presence of marker was linked to a more tumorigenic potential in the in vivo assessment and shorter disease-free survival in NSCLC patients with platinum treatment. (ijpmonline.org)
Human epidermal growth factor receptor 2 (HER2), a promising therapeutic target, can be mutated, amplified, or overexpressed in different malignancies, including non-small cell lung cancer (NSCLC). (biomedcentral.com)
Although these alterations showed adverse prognostic effects in many cancers, their clinical significance in NSCLC is controversial. (biomedcentral.com)
A total of 100 surgically resected NSCLC cases treated at King Hussein Cancer Center (KHCC) between 2009 and 2021 were examined for HER2 protein expression using immunohistochemistry (IHC). (biomedcentral.com)
Non-small cell lung cancer (NSCLC) accounts for about 85% of lung cancer cases [ 2 ]. (biomedcentral.com)
The aim of our study was to determine human telomerase reverse transcriptase ( hTERT ) mRNA expression in patients with non-small cell lung cancer (NSCLC) in order to estimate its usefulness as diagnostic and/or prognostic factor. (edu.pl)
hTERT expression were analyzed in a group of 12 females and 28 males with NSCLC using Quantitative Real-Time Polymerase Chain Reaction - the QRT-PCR method in cancerous and non-cancerous lung tissues. (edu.pl)
LTB4 can be recognized in EBC collected from lung cancer, and their concentrations found to be significantly lower than those in BALf patients using diagnosed NSCLC. (cmdm.tw)
It is difficult to determine the lymph node metastasis of patients with clinically negative lymph nodes (cN0) non-small cell lung cancer (NSCLC) before surgery. (biomedcentral.com)
Moreover, we think CSF-1 could be included as a biomarker in NSCLC screening protocols that can improve the Rabbit Polyclonal to CPZ positive predictive value of the current screening modalities, increase overall cost effectiveness and potentially improve lung cancer survival. (mindunwindart.com)

Lung adenocarcinoma (LUAD) is one of the malignant lung tumors. (hindawi.com)
Lung cancer is one of the malignant tumors for which no effective cure has been found so far. (hindawi.com)
The remaining 44% were composed of carcinomas not otherwise specified and a variety of uncommon tumors: large cell, clear cell, solid, bronchoalveolar, adenosquamous, epithelial hemangioendothelioma, oat cell, carcinoid, small cell and mucinous histological types. (biomedcentral.com)
HPVs have never been detected in adenocarcinomas or neuroendocrin tumors, and this has to be confirmed by studies of many more cases. (coek.info)
Human lung cancer is a constellation of tumors with various histological and molecular properties. (elsevierpure.com)
The organoids recapitulated the histological and molecular hallmarks of the original tumors. (elsevierpure.com)
We collected 76 surgically resected primary tumors of invasive lung adenocarcinoma, including 51 IMA and 25 non-mucinous adenocarcinomas (non-IMA). (figshare.com)
We investigated histological changes in eight cases after various treatments, and compared the molecular profiles between primary tumors and changed tumors using exome sequencing where tissue was available. (e-crt.org)
The most common path is the hematogenous spread, which occurs in tumors that have direct venous drainage to the lungs. (medscape.com)

Lung adenocarcinoma is further classified into several subtypes and variants. (wikipedia.org)
During last decades, changes have been observed in the frequency of different histological subtypes of lung cancer, one of the most common causes of morbidity and mortality, with a declining proportion of squamous cell carcinomas and an increasing proportion of adenocarcinomas, particularly in developed countries. (cdc.gov)
The general accuracy of the liquid biopsy method was observed to be lower for lung vs colorectal cancer, probably because of the greater diversity of histological subtypes and larger differences in DNA methylation patterns in lung cancer compared with colorectal cancer. (ajmc.com)
To unravel the role of the distinct genetic features of lung cancer subtypes among patients, new research opportunities and technologies have arisen that might contribute to different therapeutic decisions [ 4 , 5 ]. (aging-us.com)
In two previous studies concerning squamous cell carcinomas of the lung, DNA to HPV subtypes 6/11/16/18 (and 31133135 for one study) was detected by in situ hybridization in 7 to 30% ofthe cases. (coek.info)
A new study - a collaboration between the International Agency for Research on Cancer (IARC) and Guangdong Medical University (China) - quantifies for the first time the global burden of lung cancer incidence for the four main histological subtypes, documenting the substantial variations across world regions and their constituent countries. (who.int)
L ung cancer, the leading cause of cancer death, is divided into several histological subtypes with large differences in molecular alterations, clinical presentation, and patient outcome. (lu.se)

Like many lung cancers, adenocarcinoma of the lung is often advanced by the time of diagnosis. (wikipedia.org)
citation needed] Adenocarcinoma, like other forms of lung cancer, is usually advanced or metastatic at time of diagnosis. (wikipedia.org)
In recent years, gene expression profiling chips have been widely used in the research fields of various diseases to reveal the association between diseases and genes and provide valuable clues for the pathogenesis of diseases to determine the diagnosis and prognosis of cancer [ 5 ]. (hindawi.com)
Postoperative pathological analysis confirmed the final diagnosis to be small intestinal metastasis from primary lung cancer. (spandidos-publications.com)
Lung cancer is the leading cause of cancer-related death worldwide, with most patients presenting with metastases during diagnosis ( 1 ). (spandidos-publications.com)
Furthermore, the literature relevant to the occurrence, diagnosis and treatment of GI metastasis of lung cancer was reviewed. (spandidos-publications.com)
Small cell lung cancer (SCLC) is characterized by poor prognosis and challenging diagnosis. (frontiersin.org)
Liquid biopsy has shown potential for early cancer detection and diagnosis. (ajmc.com)
Additionally, it may be possible to create more accurate and specific liquid biopsy methods for cancer diagnosis by analyzing the methylation patterns of cancer and benign disease samples. (ajmc.com)
The study highlights the potential of liquid biopsy methods for improving cancer diagnosis and detection, suggesting that further development and validation of these methods could have important implications for improving cancer survival and quality of life," concluded the study authors. (ajmc.com)
During the longitudinal follow-up of the COPDGene Study [an average follow-up of 5.7 years (+/-1.87 years)], a total of 169 subjects diagnosed with lung cancer were matched (for age, race, sex, smoking status, average smoking pack-years and years since quitting smoking) against 671 control subjects with no reported lung cancer diagnosis. (copdx.org.au)
In the current analyses, 101 lung cancer cases that had occurred after SLE diagnosis were studied. (biomedcentral.com)
The average age of the SLE patients at lung cancer diagnosis was 60 years (median 40, standard deviation (SD) 10.9). (biomedcentral.com)
The average SLE duration at the time of lung cancer diagnosis was 13 years (median 12, SD 10.6). (biomedcentral.com)
Rationale Exposure to ambient air pollutants has been associated with increased lung cancer incidence and mortality, but due to the high case fatality rate, little is known about the impacts of air pollution exposures on survival after diagnosis. (bmj.com)
Conclusions These epidemiological findings support the hypothesis that air pollution exposures after lung cancer diagnosis shorten survival. (bmj.com)
Does exposure to ambient air pollution after diagnosis of lung cancer affect survival? (bmj.com)
Patients with lung cancer, with higher average ambient NO 2 , PM 2.5 and PM 10 exposures since diagnosis, had shorter survival, with the largest differences in survival for patients with early-stage non-small cell cancers (particularly adenocarcinomas). (bmj.com)
This is the first study to link individual-level estimates of air pollution exposures after lung cancer diagnosis to survival, and the study population was the population-based sample of 352 053 patients with newly diagnosed lung cancer during 1988-2009 in California, as ascertained by the California Cancer Registry. (bmj.com)
Immunohistochemistry and electron microscopy are invaluable techniques for diagnosis and subclassification, but our intention was to render the classification simple and practical to every surgical laboratory, so that most lung tumours could be classified by light microscopic criteria. (ersjournals.com)
1 ], and in 1975, Martini and Melamed [ 2 ] introduced the clinicopathological criteria for the diagnosis of multiple primary lung cancer (MPLC). (biomedcentral.com)
Despite the advancement of lung cancer diagnosis, surgical treatment, and chemotherapy, the overall five-year survival is around 15%, which is one of the lowest among cancers. (biomedcentral.com)
The tissue (biopsy, performed generally by fibroscopy bronchitis) or cancer cells (by sputum analysis) allow confirmation of the diagnosis. (about-health-problems.com)
Advances in molecular diagnosis and target treatments mean the future is getting brighter in lung cancer. (hospiten.com)
For that reason, the I International Congress 'The Future of Lung Cancer: a step forward' analyzes the latest advances in diagnosis and treatment with the aim of projecting a much more optimistic future for patients. (hospiten.com)
Until now, histological diagnosis allowed us to choose a chemotherapy treatment on the basis of limited information, so on occasions, the disease did not respond to the therapy. (hospiten.com)
The diagnosis was proven by lung pathology, and the patients were evaluated retrospectively. (bangkokmedjournal.com)

The cancer-associated antigen NY-ESO-1 is expressed in a number of malignancies of different histological type. (nih.gov)

In particular, specialists at the congress will look at the different molecular characteristics and prognostic factors of the two main histological types of non-small-cell lung cancer (adenocarcinoma and epidermoid) as key factors in the choice of treatment. (hospiten.com)

Due to the fact that most lung cancers are diagnosed as advanced after regional or distant spread of the malignancy, this disease has a high mortality rate worldwide [ 2 ]. (hindawi.com)
Lung cancer is currently the most frequently diagnosed major cancer and is the leading cause of cancer-related mortality in both men and women worldwide [1]. (who.int)
Lung cancer is the most common cause of global cancer-related mortality, leading to over a million deaths each year and adenocarcinoma is its most common histological type. (nature.com)
Low-dose computed tomography (LDCT) screening among high-risk populations remains an effective strategy for curbing mortality, with an observed 20% reduction in lung cancer-associated mortality ( 3 ). (frontiersin.org)
2 , 3 In China, lung cancer mortality is higher than in most other countries, and it is estimated that lung cancer mortality may surge nearly 40% between 2015 and 2030. (dovepress.com)
Multiple distant metastases are the major cause of mortality in lung cancer. (aging-us.com)
Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer and has the highest cancer mortality rate worldwide [ 1 ]. (aging-us.com)
Despite a number of factors like the increasing numbers of new cases (171,600) per year, the large numbers of current and ex-smokers at risk in the United States (50 million each), position of lung cancer as a predominant cause of death among Americans (6%), and a constant 72% mortality rate among lung cancer patients, there is almost no strategy or research funding for this epidemic even in the developed world. (ijpmonline.org)
2 In females, mortality due to lung cancer has been greater than mortality due to breast cancer since 1987. (touchoncology.com)
While stabilisation or even a decrease in the number of lung cancers in males is emerging in most European countries, mortality due to lung cancer in females is increasing. (touchoncology.com)

Postoperative pathology indicated infiltrating adenocarcinoma (right upper lobe mass) with poor differentiation and lymph node metastasis. (spandidos-publications.com)
In 1994, the WHO adopted the International Association for the Study of Lung Cancer (IASLC) pathology panel to comprise the core membership of the WHO committee, to develop a new revised classification of lung and pleural tumours. (ersjournals.com)
Current readings: pathology, prognosis, and lung cancer. (nih.gov)

Our patient had triple synchronous primary lung cancers that histologically were variant primary cancers. (biomedcentral.com)

Validation Study of New IASLC Histology Grading System in Stage I Non-Mucinous Adenocarcinoma Comparing With Minimally Invasive Adenocarcinoma. (nih.gov)
Comprehensive analysis of the clinicopathological features, targetable profile, and prognosis of mucinous adenocarcinoma of the lung. (nih.gov)

Despite the availability of various therapies including surgery, radiation, and targeted therapies, unfortunately, there are significant barriers to effective treatment of LUAD and an overall survival of less than five years in patients with lung adenocarcinoma [ 3 ]. (hindawi.com)

Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
Pulmonary carcinoids are well differentiated low to intermediate grade lung neuroendocrine tumours (LNETs), that belong to the group of lung neuroendocrine neoplasms which also include highly aggressive lung neuroendocrine carcinomas (LNECs). (who.int)
These data have been combined with previously published LNET data to perform integrative analysis using multi-omics factor analysis (MOFA), resulting in a molecular map of lung neuroendocrine neoplasms for exploration. (who.int)

This study documents for the first time the clinical and epidemiological characteristics of lung cancer cases in Qatar from 1998 to 2005. (who.int)
The aim of the present study was to document the clinical and epidemiological characteristics of lung cancer cases in Qatar. (who.int)
This suggests that the process of GI metastasis of lung cancer is subtle and lacks specific clinical symptoms. (spandidos-publications.com)
Liquid biopsy has emerged as a potential approach for guiding clinical decision-making in both early detection and in guiding therapies in cancers ( 6 , 7 ). (frontiersin.org)
The researchers determined that the MRE-seq method was more suitable for diagnosing early cancer in liquid biopsy using a small amount of cfDNA in regular clinical testing. (ajmc.com)
The correlation between miR-27a level and chemoresistance was further investigated in clinical lung adenocarcinoma specimens. (biomedcentral.com)
The American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) guidelines for breast cancer were applied to interpret the results with a final score ranging from 0 to 3+, considering a score of 3 + as overexpression. (biomedcentral.com)
A total of 105 … The gene expression profiles and the clinical parameters were obtained from The Cancer Genome Atlas-Lung adenocarcinoma (TCGA-LUAD) and Gene Expression Omnibus data set (GSE72094). (adm-astronomy.com)
Clinical and prognostic value of hTERT mRNA expression in patients with non-small-cell lung cancer. (edu.pl)
A retrospective analysis was performed by using data collected from the clinical database of the department of thoracic surgery in Harbin Medical University Cancer Hospital. (biomedcentral.com)
By a combined clinical and molecular approach the current project focuses on improving the molecular understanding of lung cancer and translate research findings into a clinical diagnostic setting. (lu.se)
By characterization of the genomic, transcriptional, and DNA methylation landscape in lung cancer subgroups defined by histology and other clinicopathological factors in both own and public cohorts we search for new molecular subgroups of potential clinical relevance, additional targets for synergistic treatment, and a deepened understanding of the molecular pathogenesis. (lu.se)

Bernatsky S, Clarke A, Petri MA, et al: Further defining cancer risk in systemic lupus: updated results in an expanded international multi-centre cohort [abstract]. (biomedcentral.com)
6 1 Blanc Inter SVSE 5 Program Edition 2010 Titre du projet BioPol folders - Biocompatible poly(amphiphiles) to fold and stabilize engineered antibody fragments for in vivo molecular imaging in cancer Abstract Unstability and aggregation of fragments of recombinant antibodies limit the therapeutic and diagnostic developments of this important class of bioproducts. (studylibfr.com)

A cohort study of 2,507 patients with COPD followed for 60 months found an incidence of lung cancer of 16.7 per 1000 patient years. (copdx.org.au)
The incidence of lung cancer is increasing, especially in centers without screening programs. (umbalk.org)
Even if the incidence of lung cancer in male non-smokers is consistently higher than in female non-smokers,8 the proportion of non-smokers in females with lung cancer is rather significant compared with males in all studies. (touchoncology.com)
In recent decades, healthcare professionals and oncology specialists have become increasingly focused on the role of second hand smoke as a cause or contributing factor to the incidence of lung cancer in non-smokers. (bangkokmedjournal.com)

Unlike other Gulf countries, adenocarcinoma was the predominant type in both Qatari nationals and expatriates (43.9% of lung cancer types). (who.int)
Lung cancer is diagnosed more frequently than any other type of cancer in both men and women, and while smoking remains the predominant cause, recent studies reveal that lung cancer rates among people who have never smoked are higher in women than in men. (bangkokmedjournal.com)

The majority of patients who are diagnosed with lung cancer usually present with locally advanced or metastatic disease. (wikipedia.org)
Biopsy of the other lesions helped us differentiate metastatic disease from primary lung cancer. (biomedcentral.com)
Twenty percent of metastatic disease is isolated to the lungs. (medscape.com)
Imaging guidance is also used in histological confirmation of metastatic disease. (medscape.com)
In patients with primary renal or testicular cancer, chest CT scanning performed should be performed based on the presence of metastatic disease elsewhere. (medscape.com)

It has been 17 years since the World Health Organization (WHO) classification was updated in 1981 1 , and since this time considerable progress has been made in understanding the epidemiological histogenetic and molecular biology of lung cancer. (ersjournals.com)
In addition to changes in smoking prevalence and cigarette composition causing a transition in the epidemiological profile of lung cancer, there is accumulating evidence of causal mechanisms linking air pollution to risk of adenocarcinoma. (who.int)

Our results suggest a similar distribution, but with a possibly lower proportion of adenocarcinomas, and a higher number of uncommon lung cancer types. (biomedcentral.com)

However, most lung adenocarcinomas either lack an identifiable driver oncogene, or harbour mutations in KRAS and are therefore still treated with conventional chemotherapy. (nature.com)
Phenotypic screening of niche factor dependency revealed that EGFR mutations in lung adenocarcinoma are associated with the independence from Wnt ligands. (elsevierpure.com)
Lung cancer is driven by different molecular alterations, including the epidermal growth factor receptor (EGFR) mutations and the rearrangements of the anaplastic lymphoma kinase (ALK) and the c-ros1 (ROS1) genes. (biomedcentral.com)
More extensive molecular testing of lung cancer, including next-generation sequencing (NGS), has identified additional potential driver mutations [ 5 ]. (biomedcentral.com)
The c-index for TCGA dataset, GSE30219, … High rates of somatic mutation were seen (mean 8.9 mutations … As a singular and unified point of reference, the Pan-Cancer Atlas is an essential resource for the development of new treatments in the pursuit of precision medicine. (adm-astronomy.com)

1 It is also the most frequent cause of death by cancer, with 1.18 million deaths. (touchoncology.com)
3 In Europe, lung cancer is the most frequent cause of death by cancer in males. (touchoncology.com)
In non-tumoral lung tissue, transversion and DNA adducts were more frequent in females even though tobacco exposure was less than in males. (touchoncology.com)
Background: Lung adenocarcinoma (LUAD) is the most frequent histological type of lung cancer, and its incidence has displayed an upward trend in recent years. (adm-astronomy.com)
pendent of those associated with cretory ducts, columnar epithelia the KRAS gene is more frequent- other key mechanistic characteris- lining the gastrointestinal tract and ly mutated in human cancer, which tics of IARC Group 1 carcinogens. (who.int)
[ 1 ] Lungs are the second most frequent site of metastases from extrathoracic malignancies. (medscape.com)

The patient's past medical history included a cerebrovascular accident with residual left-sided weakness, bronchial asthma, lung adenocarcinoma (stage IIIB) diagnosed by computed tomography (CT)-guided right upper lobe biopsy 5 months previously. (biomedcentral.com)
They are due to metastases, more often the lung and bronchial, arising either by blood or by the lymphatic from a primitive cancer whose headquarters is variable, most often located breast, digestive tract, kidney or bronchi. (about-health-problems.com)
Ground-glass opacity (GGO) is a slightly increased density on high-resolution computed tomography (HRCT) lung window, in which the bronchial and vascular textures are still visible [ 4 ]. (biomedcentral.com)
Microscopy: Infi ltrating groups of malignant cuboidal to columnar epithelial cells with glandular formation are seen in chronically infl amed anthracotic bronchial and lung tissue biopsies. (bangkokmedjournal.com)
Malignancies can reach the lung through 5 different pathways-hematogenous through the pulmonary or bronchial artery, lymphatics, pleural space, airway, or direct invasion. (medscape.com)

Finally, we correlated the expression of miR-27a and RKIP with the chemotherapeutic status and prognosis of lung adenocarcinoma patients. (biomedcentral.com)
Analysis of genes associated with prognosis of lung adenocarcinoma based on GEO and TCGA databases Medicine (Baltimore). (adm-astronomy.com)

Patients with early-stage lung cancer are asymptomatic, whereas those with advanced metastasis are frequently symptomatic due to metastatic sites. (spandidos-publications.com)
The overall 5-year survival rate of lung cancer is 16%, and the 5-year survival rate of early-stage lung cancer patients after timely treatment can be increased to 50% [ 3 ]. (biomedcentral.com)
Recent developments in imaging modalities and the widespread application of low-dose helical computed tomography (CT) for lung cancer screening have led to an increase in the detection rate of early-stage lung cancer. (biomedcentral.com)
Some patients with early-stage lung cancer appear as GGO on CT, and patients with GGO-based early-stage lung adenocarcinoma have been reported to have a favorable prognosis after surgery [ 5 ]. (biomedcentral.com)

The current study aims to construct a robust ferroptosis-related lncRNAs signature to increase the predicted value of lung adenocarcinoma (LUAD) by bioinformatics analysis. (researchsquare.com)
Lung adenocarcinoma (LUAD) is the most common type of non-small cell lung cancer and accounts for approximately 40% of all lung cancer cases. (aging-us.com)
We analyzed the gene expression profiles of LUAD patients from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO). (adm-astronomy.com)
From TCGA-LUAD obtained a risk score was an independent prognostic indicator of LUAD patients from cancer. (adm-astronomy.com)

Characteristics associated with a future risk of lung cancer included airflow obstruction as measured by FEV 1 /FVC, history of exacerbations in the previous year and the presence of visual emphysema. (copdx.org.au)
We assessed the demographic characteristics for all lung cancer cases in the SLE patients, and information on histology types was analyzed from the centers where this information was available. (biomedcentral.com)
Most of this classification is based on the histological characteristics of tumours seen in surgical or needle biopsy, and is primarily based on light microscopy, although immunohistochemistry and electron microscopy findings are provided when necessary. (ersjournals.com)
Despite previous genomic studies on lung IMA, the genetic characteristics and the prognosis-related biomarkers in Chinese surgically resected lung IMA remain unclear. (figshare.com)

Our results show that miR-27a has the potential as key regulatory factors for the chemotherapy resistance and metastasis of lung adenocarcinoma. (biomedcentral.com)

Although SCLC constitutes the minority of lung cancer cases, it represents an aggressive form of cancer characterized by a high growth fraction, early development of metastases, and extremely poor prognosis, with less than 7% 5-year survival rate ( 2 ). (frontiersin.org)
This study aimed to determine whether ambient air pollutant exposures are associated with the survival of patients with lung cancer. (bmj.com)
Although progress has been made in each area, lung cancer survival remains stubbornly poor, suggesting that novel approaches are needed. (bmj.com)
These findings are important for cancer treatment planning and help professionals to seek greater survival. (bvsalud.org)

Axial CT scan in a 58-year-old man with malignant melanoma shows multiple round nodules and masses of varying sizes in both lungs, consistent with metastases. (medscape.com)

However, we found a rare mutation of EGFR Ex19del/G724S in two patients with lung cancer who demonstrated a favorable response to the combination of afatinib and chemotherapy. (frontiersin.org)
In this study, we reported two patients with EGFR Ex19del/G724S lung cancer who appeared in remission after being treated with afatinib and chemotherapy. (frontiersin.org)
Increased risk of recurrence in resected EGFR-positive pN0M0 invasive lung adenocarcinoma. (nih.gov)
Transformed SCC after TKI treatment in EGFR -mutant adenocarcinoma (AdenoCa) branched out early from the clones with completely inactivated RB1 and TP53 [ 7 ]. (e-crt.org)
EGFR -mutant lung cancers with RB1 / TP53 alterations are at exceptionally high risk for SCC transformation [ 9 ]. (e-crt.org)

The occurrence of small intestinal metastases from primary lung cancer is rare. (spandidos-publications.com)
After a locoregional evolution, primitive lung cancers can work extrathoracic metastases, of which the most common are bone and liver brain. (about-health-problems.com)
Treatment of cancers "other than small cell" depends on their scope in the chest, just outside of (metastases), and respiratory function status of the subject. (about-health-problems.com)

The objective of this study is to confirm limited resection efficacy as radical surgery in patients with minimally invasive lung cancer as indicated by high-resolution (HR) computed tomography (CT), and to confirm intraoperative cytology as a negative margin indicator and reliable margin non-recurrence predictor. (iaslc.org)
A morphologic variant of minimally invasive lung adenocarcinoma characterized by tall columnar cells and mucin production. (nih.gov)

We analysed tumour and matched normal material from 230 previously untreated lung adenocarcinoma patients who provided informed consent ( Supplementary Table 1 ). (nature.com)
It was a Pilot study where biopsies from 55 fresh previously untreated lung cancer patients visiting the Pulmonary Medicine Department of Era's Lucknow Medical College and Hospital Lucknow and King George's Medical University were taken for 18 months November 2014-April 2016, after taking proper informed consent from them. (ijpmonline.org)

Treatment of small cell cancer is based on combination chemotherapy (making use of several drugs). (about-health-problems.com)

We used the two-sample Mendelian randomization (MR) approach to circumvent these limitations of observational epidemiology by constructing a genetic instrument for BMI, based on results from the GIANT consortium, which was evaluated in relation to lung cancer risk using GWAS results on 16,572 lung cancer cases and 21,480 controls. (liverpool.ac.uk)

About 90% of lung cancer cases occur in smokers or former smokers. (who.int)
Smoking is the major cause of lung adenocarcinoma but, as smoking rates decrease, proportionally more cases occur in never-smokers (defined as less than 100 cigarettes in a lifetime). (nature.com)
According to the GLOBOCAN 2020 report by the World Health Organization's International Agency for Research on Cancer, ~2.2 million new cases of lung cancer occur worldwide each year, making it the world's second most common but most fatal cancer type ( 2 , 3 ). (spandidos-publications.com)
1 In 2018, approximately 2.09 million new lung cancer cases took place, ranking first in all cancer types. (dovepress.com)
Our objective was to provide an updated analyses of the lung cancer cases from a multi-site international cohort study, including descriptive statistics of the demographics (age, sex, and race/ethnicity) of cases, as well the of histology. (biomedcentral.com)
The lung cancer cases were distributed across 21 centers. (biomedcentral.com)
Histological lung cancer type was only provided by 12 centers (59 cases). (biomedcentral.com)
It accounts for 6.9% of new cancer cases detected each year. (ijpmonline.org)
Results: Among 10800 cancer cases registered during this period, 238 cases were lung cancer, including 76.1% male and 23.9% female patients. (ac.ir)
66.1% of the lung cancer cases were smokers. (ac.ir)
Lung cancer is the most common cancer in the world and, by 2002, there were 1.35 million new cases, representing 12.4% of all new cancers. (touchoncology.com)
Worldwide, in 2000 an estimated 85% of lung cancer cases in men and 47% in women were attributable to tobacco smoking. (touchoncology.com)
Moreover, there is now a convergence between lung cancer incidence in the youngest birth cohorts, reflecting the convergence in cigarette use in males and females.6 In Europe, about 70% of lung cancer cases in females are attributed to an active smoking habit versus 85% in males, 7 whereas in Asia very few lung cancer cases in females are attributable to tobacco smoking. (touchoncology.com)
Treatment depends mainly on the nature of primitive cancer, in exceptional cases, treatment may be surgery. (about-health-problems.com)
Introduction Lung cancer is the most common incident form of cancer worldwide, with an estimated 1.8?million new cases in 2012, representing 12.9% of all new cancer cases. (mindunwindart.com)
Every year, about 25,000 new cases of lung cancer are detected in Spain. (hospiten.com)
The study found 101 women among 1,680 cases of lung cancer. (bangkokmedjournal.com)
Overlapping lung and pleural involvement in individual cases has given rise to the more inclusive term "pleuropulmonary" synovial sarcoma. (medscape.com)
Globally, there were an estimated 2 206 771 new cases of lung cancer in 2020: 1 435 943 in males and 770 828 in females. (who.int)
TNBC is a subgroup of breast cancer, representing ~10% of all cases (9% in Sweden 2015). (lu.se)

Patients with lung cancer are at an increased risk of developing secondary lung cancers at the same time as the first (synchronous) or later in life (metachronous). (biomedcentral.com)
At radiography, secondary lung cancers can take many different aspects. (about-health-problems.com)

Our patient's case suggests that multiple primary lung cancers may still occur at a greater rate than can be detected by high-resolution computed tomography. (biomedcentral.com)
In 1924, the first case of two distinct primary lung cancers was published by Beyreuther et al . (biomedcentral.com)
Albanell J, Lonardo F, Rusch V, Engelhardt M, Langenfeld J, Han W, Klimstra D, Venkatraman E, Moore MA, Dmitrovsky E (1997) High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage. (edu.pl)

To better understand the biological mechanisms of chemoresistance in lung adenocarcinoma cells and search for the reversion opportunities, we made use of a cisplatin-sensitive and derived resistant lung cancer cell line pair (A549 and A549/ CDDP). (biomedcentral.com)
A methylation- and immune-related lncRNA signature to predict ovarian cancer outcome and uncover mechanisms of chemoresistance. (cdc.gov)

Adenocarcinoma of the lung is the most common type of lung cancer, and like other forms of lung cancer, it is characterized by distinct cellular and molecular features. (wikipedia.org)
The signs and symptoms of this specific type of lung cancer are similar to other forms of lung cancer, and patients most commonly complain of persistent cough and shortness of breath. (wikipedia.org)
Contrairement aux autres pays du Golfe, l'adénocarcinome était le type prédominant (43,9 % des types de cancer du poumon), à la fois chez les Qatariens d'origine et chez les personnes expatriées. (who.int)
his mother had colon cancer, and his brother had an unknown type of cancer. (biomedcentral.com)

J Cancer Res Clin Oncol 2021 Dec;147(12):3709-3718. (nih.gov)

Asbestosis is a diffuse interstitial fibrosis of lung tissue resulting from inhalation of asbestos fibers. (cdc.gov)
Asbestos fibers inhaled deep into the lung become lodged in the tissue, eventually resulting in diffuse alveolar and interstitial fibrosis. (cdc.gov)
In 1996, we formally recognized and described non-angiogenic tumours in lungs where the only blood vessels present were those originating from normal lung tissue. (nature.com)
We focus our attention on lung stem cells and the molecular signals that regulate their activity to repair and regenerate lung tissue after injury. (stanford.edu)
Our experimental approaches involve mouse genetics, single cell genomics, organoid culture, lung slice culture, and we perform histological analysis of lung tissue using advanced fluorescence microscopy technologies. (stanford.edu)
This is in contrast to other soft tissue sarcomas in which the lung is the most common site of metastasis. (medscape.com)

[ 3 ] Lymphatic spread also occurs to the mediastinal lymph nodes through the thoracic duct, with subsequent retrograde spread to the hilar lymph nodes and then the lungs. (medscape.com)
Nodal involvement confirmation may be either histological eg, biopsy or by imaging PET CT, CT or MRI with pathological lymph node size defined by a short axis diameter of 10 mm axial plane. (who.int)

Differentially expressed genes were obtained by comparing gene expression between lung adenocarcinoma samples and normal samples. (hindawi.com)

The most common category of nonmesotheliomatous cancer to involve the pleura is represented by extrapleural primary malignancies that secondarily involve the pleura via metastatic spread. (medscape.com)
When considering all primary malignancies of the small bowel, adenocarcinomas tend to occur more proximally, whereas carcinoids , lymphomas, and leiomyosarcomas occur more distally. (medscape.com)

In this Opinion article, we summarize how these tumours were discovered and discuss what we know so far about their biology and the potential implications of this knowledge for cancer treatment. (nature.com)

A series of 31 frozen biopsies of lung carcinomas were examined for the presence of HPV DNA by nested polymerase chain reaction (PCR). (coek.info)

Whereas pleural mesothelioma is highly associated with asbestos exposure , nonmesotheliomatous cancers have generally not been proven to result from exposure to airborne asbestos. (medscape.com)
[ 5 ] An earlier report, in 1956, by Babolini and Blasi, described the same clinicopathological entity using the nomenclature, "The pleural form of primary cancer of the lung. (medscape.com)

In this study, three lung adenocarcinoma datasets were downloaded from the GEO. (hindawi.com)
The analyzed gene datasets were downloaded from the Gene Expression Omnibus and The Cancer Genome Atlas (TCGA) database. (cancerindex.org)
M conducting research using TCGA lung cancer datasets in high-risk score group Individualized Multi-Omic Deviation! (adm-astronomy.com)

Distinctive clinicopathological features of adenocarcinoma in situ and minimally invasive adenocarcinoma of the lung: A retrospective study. (nih.gov)

The transcriptome data were abstracted from The Cancer Genome Atlas (TCGA). (researchsquare.com)
And patient outcomes lung is the leading cause of cancer death worldwide assigning both a TCGA barcode and UUID! (adm-astronomy.com)

Dr. Desai conducts basic and translational research on lung stem cells that repair and regenerate the lung after injury, and their role in diseases like IPF, Chronic Obstructive Pulmonary Disease (COPD), and lung adenocarcinoma. (stanford.edu)

Adenocarcinoma is more common in patients with a history of cigarette smoking, and is the most common form of lung cancer in younger women and Asian populations. (wikipedia.org)
In order of highest frequency, the most common signs of lung cancer include: cough that does not go away or gets worse weight loss dyspnea (shortness of breath or difficulty breathing) chest pain, which may be aggravated by deep breathing, coughing, or laughing hemoptysis (coughing up blood or rust-colored phlegm) bone pain clubbing fever generally feeling tired or weak superior vena cava obstruction- facial, neck, upper torso swelling. (wikipedia.org)
Furthermore, the gastrointestinal (GI) tract is not a common site of primary lung cancer metastasis ( 4 ). (spandidos-publications.com)
Lung cancer has been the most common cancer for decades. (bmj.com)
Primary lung cancer - is the most common cancer in the world. (about-health-problems.com)
Because of the rich vascularity of the lung, these cancers are very common. (about-health-problems.com)
Breast cancer is the most common malignancy in women and a heterogeneous disease at the molecular level. (lu.se)

The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)

Cigarette smoke is the number one cause of lung cancer. (who.int)
Smoking is the largest single cause of lung cancer, responsible for 90% of lung cancers in males and 65% of lung cancers in females in Australia. (copdx.org.au)
Smoking habits vary within the different countries in Europe, with a significant decrease in tobacco consumption in the UK, Sweden and Finland between 1970 and 1994 and a significant increase in Portugal (+64.2%).5 Even if active tobacco smoking is the main cause of lung cancer in females, the attributable risk is inferior to that noted in males. (touchoncology.com)
smoking is the leading cause of lung cancer primitive. (about-health-problems.com)

Thorac Cancer 2018 Dec;9(12):1594-1602. (nih.gov)

In March 2020, 2 months after initial symptom development, the patient underwent a computed tomography (CT) scan, which revealed a mass 6.5×6.2×7.2 cm in size in the upper lobe of the right lung ( Fig. 1A ). (spandidos-publications.com)
Patients with previously treated lung cancer are at risk for developing metachronous lung cancer, but with the success of computed tomography and positron emission tomography, the ability to detect both synchronous and metachronous lung cancer has increased. (biomedcentral.com)

Lung cancer has emerged as the leading cause of cancer-associated deaths worldwide, accounting for about 20% of all cancer deaths. (dovepress.com)
Worldwide, lung cancer causes nearly one in five cancer deaths, about 1.59 million deaths annually ( http://globocan.iarc.fr ). (bmj.com)
Of late as per WHO Lung cancer deaths are declining in men, and the death rate in women has plateaued secondary to decreases in smoking. (ijpmonline.org)
[1] However, 9.3% of cancer-related deaths in both the sexes is still attributed to lung cancer. (ijpmonline.org)
Lung cancer is a primary cause of cancer-related deaths for both genders worldwide [ 1 ]. (biomedcentral.com)

There has been substantial evolution of concepts in neuroendocrine lung tumour classification. (ersjournals.com)
Later, bronchoscopy incidentally revealed the patient to have an endobronchial lesion that turned out to be mixed small and large cell neuroendocrine lung cancer. (biomedcentral.com)

Anatomy13

Organisms4

Diseases63

Chemicals and Drugs54

Analytical, Diagnostic and Therapeutic Techniques and Equipment72

Psychiatry and Psychology1

Phenomena and Processes39

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture1

Humanities1

Information Science8

Named Groups1

Health Care32

Geographicals3

Carcinoma34

Subtype5

Tumor36

NSCLC21

Tumors9

Subtypes7

Diagnosis27

Different histological1

Main histological1

Mortality10

Pathology3

Histologically1

Mucinous adenocarcinoma2

Patients with lung adenocarcinoma1

Neoplasms3

Clinical12

Abstract2

Incidence of lung cancer4

Predominant2

Metastatic disease5

Epidemiological2

Proportion of adenocarcinomas1

Mutations5

Frequent6

Bronchial5

Prognosis of lung adenocarcinoma2

Early-stage lung cancer4

LUAD4

Characteristics4

Metastasis of lung1

Survival4

Malignant1

EGFR5

Metastases3

Minimally invasive lung2

Previously untreated lung2

Chemotherapy1

Epidemiology1

Cases20

Secondary lung cancers2

Primary lung cancers3

Mechanisms of chemoresistance2

Type4

20211

Tissue6

Lymph2

Expressed genes1

Malignancies2

Tumours1

Carcinomas1

Pleural2

Datasets3

Clinicopathological1

TCGA2

Chronic Obstruc1

Common7

Tissues1

Cause of lung cancer4

20181

Computed tomography2

Deaths5

Neuroendocrine lung2