• CK7, CK20, CDX2 and MUC2 Immunohistochemical staining used to distinguish metastatic colorectal carcinoma involving ovary from primary ovarian mucinous adenocarcinoma. (novodiax.com)
  • This picture depicts an abdominal CT scan of a 7 year-old boy with a mucinous adenocarcinoma of the ascending colon. (medscape.com)
  • Transitional cell and squamous cell carcinomas are the most common but there are three reported cases of mucinous adenocarcinoma. (biomedcentral.com)
  • We report a 57-year-old Caucasian man presenting with penile discharge for 30 years following ileal conduit surgery for neurogenic bladder, and who was found to have primary mucinous adenocarcinoma of his defunctionalized bladder. (biomedcentral.com)
  • We describe the fifth case of primary mucinous adenocarcinoma arising in a longstanding defunctionalized bladder. (biomedcentral.com)
  • Prostate biopsies showed mucinous adenocarcinoma in six of eight cores with large collections of mucin dissecting the prostatic parenchyma. (biomedcentral.com)
  • Bladder washings and biopsies revealed copious amounts of mucin with associated malignant nests and single cells also consistent with mucinous adenocarcinoma. (biomedcentral.com)
  • The year 2022 was notable for substantial research progress related to pancreatic ductal adenocarcinoma (PDAC). (nature.com)
  • Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death and is one of the most difficult-to-treat cancers. (biomedcentral.com)
  • Esophageal cancer can arise as esophageal squamous cell carcinoma (ESCC) or esophageal adenocarcinoma (EAC), which have distinct etiological and pathological characteristics. (annexpublishers.com)
  • Mendelian randomization analyses demonstrate that reduced FEV 1 increases squamous cell carcinoma risk (odds ratio (OR) = 1.51, 95% confidence intervals: 1.21-1.88), while reduced FEV 1 /FVC increases the risk of adenocarcinoma (OR = 1.17, 1.01-1.35) and lung cancer in never smokers (OR = 1.56, 1.05-2.30). (nature.com)
  • Journal of Thoracic Disease 5:E17-20 Tsao MS, Fraser RS (1991) Primary pulmonary adenocarcinoma with enteric differentiation. (wikipedia.org)
  • Pulmonary adenocarcinoma is a common neoplasm, yet the one with enteric or intestinal differentiation poses a diagnostic challenge to pathologists as it shares a common immunohistochemical profile with metastatic colorectal carcinoma. (elsevierpure.com)
  • The morphology and immune histochemical profile raised the differential diagnosis of a metastatic colorectal carcinoma and a primary lung adenocarcinoma with enteric differentiation. (elsevierpure.com)
  • The differential diagnosis includes glandular differentiation of transitional cell carcinoma and direct extension or metastatic spread of adenocarcinoma arising primarily from the colon, prostate, appendix or endometrium. (biomedcentral.com)
  • citation needed] The typical histological appearance of this tumour of tall columnar cells arranged in an irregular glandular cavity or cribriform pattern with extensive central necrosis. (wikipedia.org)
  • Morphology was consistent with a moderately differentiated adenocarcinoma .The tumour cells were positive for cytokeratin (CK) 7, CDX2, CK20 and were negative for thyroid transcription factor 1. (elsevierpure.com)
  • Histopathologically, the tumour was moderately differentiated tubular adenocarcinoma that invaded the sphincter of Oddi with four nodal metastases, and all margins were free of tumour cells. (springeropen.com)
  • A group of disorders having a benign course but exhibiting clinical and histological features suggestive of malignant lymphoma. (lookformedical.com)
  • Key studies published in 2022 further established the importance of alterations in the gut microenvironment and interactions with the enteric and central nervous systems in symptom generation in irritable bowel syndrome and suggested novel and clinically accessible therapeutic approaches for this large group of patients. (nature.com)
  • The GDNF family ligands (GFLs) function through a glycosyl-phosphatidylinositol-(GPI) anchored coreceptor, GDNF family receptor alpha (GFRα), and rearranged during transfection (RET), a well-known receptor tyrosine kinase involved in kidney development, spermatogonial stem cell maintenance, and the development and maintenance of the sympathetic, parasympathetic, and enteric nervous systems [ 1 , 2 ]. (medsci.org)
  • the largest was surgically removed for histological examination. (elsevierpure.com)
  • Examination of Abnormal Alpha-synuclein Aggregates in the Enteric Neural Plexus in Patients with Ulcerative Colitis. (nagoya-u.ac.jp)
  • The potential for adenocarcinoma to develop in the defunctionalized bladder that is left in-situ at the time of urinary diversion is rare [ 3 - 5 ]. (biomedcentral.com)
  • International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. (radiopaedia.org)
  • Salivary Gland Polymorphous Adenocarcinoma: Clinicopathological Features and Gene Alterations in 36 Japanese Patients. (nagoya-u.ac.jp)
  • Mesenteric fat, vessels and lymph nodes were resected en block with the ascending colon. (medscape.com)
  • The diagnosis of erysipelas in slaughter pigs becomes a challenge for pathologists, since scalding and dehairing, routine procedures in slaughterhouses, generate histological artifacts that often make the final diagnosis impossible. (pvb.org.br)
  • ESCC is the most common histological type of esophageal cancer in the Eastern world, and its incidence remains stable. (annexpublishers.com)
  • However, adenocarcinoma has now become the leading type of esophageal cancer in the United States, representing 80% of cases. (annexpublishers.com)
  • Concomitant cystitis glandularis occurs in the majority of cases, but is not considered a definitive precursor lesion since adenocarcinoma can develop in the absence of cystitis glandularis and only a small number of bladders with cystitis glandularis actually develop malignancies [ 2 ]. (biomedcentral.com)
  • Histological assessment of nonalcoholic fatty liver disease (NAFLD) has anchored knowledge development about the phenotype. (cn1699.cn)
  • Pulmonary enteric adenocarcinoma is rare subtype of pulmonary adenocarcinoma. (wikipedia.org)
  • Journal of Thoracic Disease 5:E17-20 Tsao MS, Fraser RS (1991) Primary pulmonary adenocarcinoma with enteric differentiation. (wikipedia.org)
  • In 2011, an updated classification of pulmonary adenocarcinoma was issued jointly by the International Association for the Study of Lung Cancer (IASLC), the American Thoracic Society (ATS) and the European Respiratory Society (ERS). (cap.org)
  • 5. Enteric-type thymic adenocarcinoma: a case report and literature review focusing on prognosis based on histological subtypes. (nih.gov)
  • NSCLC accounts for ∼ 85% of all lung cancers and has multiple histological subtypes including adenocarcinoma and central squamous cell carcinoma . (amboss.com)
  • 4. Adenocarcinoma of the thymus, enteric type: report of 2 cases, and proposal for a novel subtype of thymic carcinoma. (nih.gov)
  • A second major change in the IASLC/ATS/ERS classification is modification of the WHO category of "mixed subtype," which comprised roughly 85% of all lung adenocarcinomas and encompassed a wide variety of tumors with variable prognosis. (cap.org)
  • There are no published specific imaging features for this histological subtype of lung cancer. (radiopaedia.org)
  • About 2/3 of tumors stain for keratin 7 and keratin 20, which may help differentiate them from colorectal adenocarcinomas in which less than 5% show this pattern. (surgpath4u.com)
  • The most common malignant neoplasms in the small intestine are adenocarcinomas, followed by carcinoid tumors, lymphomas and sarcomas. (surgpath4u.com)
  • The pattern-based (Silva) classification of invasive HPV-associated endocervical adenocarcinomas (HPVA) is an established and reproducible method to predict outcomes for this otherwise stage-dependent group of tumors. (stanford.edu)
  • The histological examination showed an adenocarcinoma of the duodenum, that we did not consider in our differential diagnosis since the first CT scan and the surgical exploration of the abdomen did not show any sign of duodenal obstruction or pancreatic head carcinoma. (ispub.com)
  • This histological diagnosis might have implications for potential future therapies. (biomedcentral.com)
  • While most small bowel adenocarcinomas are found in the duodenum, this unusual one arose from the jejunum . (surgpath4u.com)
  • The large majority of adenomas and adenocarcinomas occur in the duodenum, where 65% arise in the periampullary region. (surgpath4u.com)
  • The absence of the H+/K+ -ATPase is chronically associated with achlorhydria and mucosal hyperplasia but with no histological evidence for neoplasia. (medscape.com)
  • Histological growth patterns and molecular analysis of resected colorectal lung metastases. (cdc.gov)
  • In contrast to colorectal adenocarcinoma where invasion into the lamina propria is considered carcinoma-in-situ or Tis due to the lack of lymphatics in the colorectum, invasion into the lamina propria is considered stage T1 as the small bowel is flush with intramucosal lymphatics (Iacobuzio). (surgpath4u.com)
  • CK7/CK20 IHC studies will be helpful in distinguishing small intestinal adenocarcinoma (CK7+/CK20+) from metastatic colorectal adenocarcinoma (CK7-/CK20+). (surgpath4u.com)
  • 3.0 cm) adenocarcinoma with growth restricted to neoplastic cells along preexisting alveolar structures (lepidic growth), lacking stromal, vascular or pleural invasion. (cap.org)
  • 2. Histologic characteristics of thymic adenocarcinomas: Clinicopathologic study of a nine-case series and a review of the literature. (nih.gov)
  • The provided sections demonstrate an invasive, non-mucinous adenocarcinoma of the lung with a wide range of histologic growth patterns. (cap.org)
  • Other mouse models have shown that a hypochloric stomach environment leads to enteric bacterial overgrowth, which may play a role in gastric atrophy, metaplasia, and cancer. (medscape.com)
  • It's a good idea to look for supplements that are coated (enteric coating) so they will dissolve in the intestine and not in the stomach. (supplemented.net)
  • To evaluate the clinicopathologic characteristics and outcome of tumor cells spreading through air spaces in patients with adenocarcinoma of lung]. (cdc.gov)
  • Molecular Correlates of Invasion Pattern in HPV-Associated Endocervical Adenocarcinoma: Emergence of Two Distinct Risk-Stratified Tiers. (stanford.edu)
  • 11. Mucinous cystic tumor with CK20 and CDX2 expression of the thymus: Is this a benign counterpart of adenocarcinoma of the thymus, enteric type? (nih.gov)
  • This case first appeared as Performance Improvement Program in Surgical Pathology (PIP) 2013, case 22, and is adenocarcinoma, predominantly acinar type. (cap.org)
  • Taken in totality, the tumor is best classified as adenocarcinoma, predominantly acinar type. (cap.org)
  • Enteric type urachal adenocarcinoma: a case report. (mcmaster.ca)
  • Lin D, Zhao Y, Li H, Xing X (2013) Pulmonary enteric adenocarcinoma with villin brush border immunoreactivity: a case report and literature review. (wikipedia.org)
  • Patients with FAP have a 100-200 fold risk for developing adenocarcinoma of the small intestine, and those with Crohn disease or celiac sprue have an 80 fold risk (Iacobuzio). (surgpath4u.com)
  • Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients. (surgpath4u.com)
  • Prognostic and predictive significance of podocalyxin-like protein expression in pancreatic and periampullary adenocarcinoma. (medscape.com)
  • Kirsten rat sarcoma virus protein overexpression in adenocarcinoma lung: Association with clinicopathological and histomorphological features. (cdc.gov)
  • The ENS is derived from enteric neural crest-derived cells (ENCCs), which colonize the gut during development. (helsinki.fi)
  • We present an original article about an interesting and challenging case: a patient with abdominal discomfort, dyspepsia due to a giant hydatid cyst of the liver causing obstruction of upper digestive canal, reduction of hepatic function, hepatomegaly and hiding an occult duodenal adenocarcinoma marked by a very fast evolution. (ispub.com)
  • The aim of this paper is to present a challenging and interesting case report of a patient with a giant hydatid cyst of the liver causing obstruction of the upper digestive canal, reduction of hepatic function, hepatomegaly and hiding an occult duodenal adenocarcinoma. (ispub.com)
  • SCLC is a single histological category and is characterized by its central location, rapid tumor growth, early metastasis , and association with numerous paraneoplastic syndromes . (amboss.com)
  • Literature review part: The enteric nervous system (ENS) often called "the second brain" is considered its own autonomic division that can independently regulate gut function. (helsinki.fi)
  • Furthermore, small intestinal adenocarcinomas lack responsiveness to chemotherapy. (surgpath4u.com)
  • The prevalence of HSCR is 1:5000, and it is characterized by a complete lack of enteric neurons (aganglionosis) in the distal colon. (helsinki.fi)
  • The jejunum is an unusual site for small intestinal adenocarcinoma but was seen in this patient. (surgpath4u.com)
  • Adenocarcinomas of the small intestine display the same adenoma-dysplasia-carcinoma sequence seen in the colon. (surgpath4u.com)
  • Small bowel adenocarcinomas are regarded as highly fatal. (surgpath4u.com)
  • Comparison of time-motion analysis of conventional stool culture and the BD MAX™ Enteric Bacterial Panel (EBP). (medscape.com)
  • 5-year survival rates range from 20% to 30% (Chaiyasate, Dabaja), although en bloc wide excision has yield a 70% 5 year survival rate in some cases (Kumar). (surgpath4u.com)