• A new study - a collaboration between the International Agency for Research on Cancer (IARC) and Guangdong Medical University (China) - quantifies for the first time the global burden of lung cancer incidence for the four main histological subtypes, documenting the substantial variations across world regions and their constituent countries. (who.int)
  • Chemoresistance is a significant barrier to the treatment and management of non-small cell lung cancer (NSCLC). (dovepress.com)
  • In this study, we demonstrated that NSCLC-derived CAFs were innately resistant to cisplatin treatment and CAFs-conditioned medium significantly promoted the survival rate of NSCLC cells after cisplatin treatment. (dovepress.com)
  • Additionally, CAFs-derived exosomes were taken up by NSCLC cells. (dovepress.com)
  • Moreover, exosomal miRNA-130a was transferred from CAFs to recipient NSCLC cells and knockdown of miRNA-130a reversed the effect of CAFs-derived exosomes during chemoresistance of NSCLC cells. (dovepress.com)
  • Taken together, these results suggest that CAFs-derived exosomes confer cisplatin resistance of NSCLC cells through transferring miRNA-130a and that PUM2 is a critical factor for packaging miRNA-130a into exosomes. (dovepress.com)
  • This study explored the expression of Ln5 and the role of its relationships with PTEN, phospho-EGFR (p-EGFR) and phospho-Akt (p-Akt) in the prognosis of patients with non-small cell lung cancer (NSCLC). (spandidos-publications.com)
  • Lasp1 (LIM and SH3 domain protein 1) promotes tumor proliferation and invasion in multiple cancer entities including non-small cell lung cancer (NSCLC). (oncotarget.com)
  • Proliferation and invasion assay showed that Lasp1 dramatically promoted the ability of proliferation and invasion of NSCLC cells. (oncotarget.com)
  • Previous studies had confirmed that Lasp1 was significantly overexpressed in multiple malignant tumors including non-small-cell lung cancer (NSCLC) and enhanced tumor proliferation, invasion and metastasis [ 7 - 13 ]. (oncotarget.com)
  • In recent years, there has been a major paradigm shift in the management of non-small cell lung cancer (NSCLC). (amegroups.org)
  • Over the last decade, molecular translational research advances have heralded major breakthroughs in the understanding, diagnosis and management of lung cancer, particularly for the more common (~80%) non-small cell lung cancer (NSCLC). (amegroups.org)
  • It is difficult to determine the lymph node metastasis of patients with clinically negative lymph nodes (cN0) non-small cell lung cancer (NSCLC) before surgery. (biomedcentral.com)
  • Lung cancer has become the most common malignant tumor in China with the highest morbidity and mortality, of which non-small cell lung cancer (NSCLC) accounts for 80% [ 1 , 2 ]. (biomedcentral.com)
  • In this retrospective study, we included 111 patients with stage IIIB and IV non-small cell lung cancer (NSCLC) who presented to our clinics between 2005 and 2006. (hasekidergisi.com)
  • Background: This study aimed to determine the relationship between the pre-operative metabolic tumor volume (MTV) and the disease-free survival (DFS) of patients with stage I non-small cell lung cancer (NSCLC) using F-18 2-fluoro-2-deoxy-D-glucose (FDG) positron-emission tomography-computed tomography (PET-CT) scanning. (iiarjournals.org)
  • Stage I non-small cell lung cancer (NSCLC), including T1N0M0 and T2aN0M0 ( 1 ), is a common form of cancer. (iiarjournals.org)
  • The histological pattern, HPV type, and grading do not affect prognosis. (cytojournal.com)
  • Most tumors are confined to the ovary at diagnosis, and malignant Brenner tumors have a better prognosis than other epithelial ovarian carcinomas. (cap.org)
  • Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological and molecular characteristics limiting the standard tumor−node−metastasis prognosis classification. (nature.com)
  • The large cell carcinoma class has been enriched with several variants, including the LCNEC and the basaloid carcinoma, both with a dismal prognosis. (ersjournals.com)
  • Large cell esophageal NECs are typically associated with rapid growth and poor prognosis [ 5 ]. (biomedcentral.com)
  • Prognosis --Several studies have demonstrated that a large proportion of neuroendocrine differentiated prostatic neoplasms are positive for neuron-specific enolase and chromogranin A [4,6]. (cancernetwork.com)
  • Since haemostatic metastasis has been proven to occur primarily by clustered CTCs ( Nature 514(7522) (2014)">4 , Cell 158(5) (2014)">5 ), assessing the perioperative clustered CTC status and the prognosis of VFL and no-VFL cases will be useful in understanding the clinical implications of VFL for lung cancer. (cancerdiagnosisprognosis.org)
  • There are no studies comparing the prognosis for mature T-cell lymphoma (TCL) in people with human immunodeficiency virus (PWH) to people without HIV (PWoH) and to AIDS-defining B-cell lymphomas (A-BCL) in the modern antiretroviral therapy (ART) era. (cdc.gov)
  • Large-cell neuroendocrine carcinoma of the lung (LCNEC of the lung), or pulmonary large-cell neuroendocrine carcinoma (PLCNC), is a highly malignant neoplasm arising from transformed epithelial cells originating in tissues within the pulmonary tree. (wikipedia.org)
  • By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
  • Synovial sarcoma is a malignant soft-tissue neoplasm that most commonly affects the extremities near to, but not in continuity with, large joints. (medscape.com)
  • Urine cytology showed leucocytes and occasional urothelial cells but no malignant cells. (urotoday.com)
  • Malignant Brenner tumors are uncommon ovarian carcinomas and represent less than 5% of all Brenner tumors. (cap.org)
  • They are composed of irregular nests of malignant cells with stromal invasion, often associated with a desmoplastic reaction. (cap.org)
  • Oral squamous cell carcinoma (OSCC) is the most common type of head and neck malignant tumor and is ranked the eighth leading cause of cancer worldwide. (nature.com)
  • A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. (lookformedical.com)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (lookformedical.com)
  • An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. (lookformedical.com)
  • Histologically, this malignant epithelial pancreatic neoplasm of the exocrine cells is characterized by multiple lines of differentiation (acinar, ductal, mesenchymal, neuroendocrine) and the presence of squamoid nests. (orpha.net)
  • It is a malignant embryonal tumor that seems to recapitulate the embryogenesis of the pancreas, presumably because it originates from the pluripotent pancreatic stem cells during foregut development. (orpha.net)
  • The most prevalent malignant growth in women worldwide is breast carcinoma, which encompasses numerous diseases with varying histological, prognostic, and clinical outcomes. (hilarispublisher.com)
  • However, implantation of malignant cells along the needle tract is an extremely rare complication after FNAB, which can change a potentially resectable localized lung metastsis to an unresectable carcinoma. (cdlib.org)
  • Renal cell carcinoma (RCC) accounts for 2% of all cancers. (urotoday.com)
  • RCC, renal cell carcinoma. (urotoday.com)
  • A 39-year-old man, who had undergone left nephrectomy for renal cell carcinoma of clear cell type, was noted to have a solitary nodular shadow in the right lung on chest X-ray. (cdlib.org)
  • Histological examination of a biopsy of the skin tumor revealed features of metastatic renal cell carcinoma of clear cell type. (cdlib.org)
  • This case represents an unusual clinical presentation of metastatic renal cell carcinoma that appears to have been translocated to the skin by the needle biopsy. (cdlib.org)
  • Percutaneous fine needle aspiration biopsy of the lung via the right anterior chest wall, using a 20 gauge fine needle, showed metastasis from renal cell carcinoma. (cdlib.org)
  • Histological examination of a skin biopsy of the cutaneous nodule revealed features of metastasis from renal cell carcinoma of clear cell type (Figure 2). (cdlib.org)
  • The lung is one of the most frequently affected metastatic sites in patients with renal cell carcinoma. (cdlib.org)
  • Nearly 30 percent of all patients with renal cell carcinoma will eventually present with metastatic disease after radical nephrectomy. (cdlib.org)
  • Many reports suggest a role for pulmonary metastasectomy in managing metastatic renal cell carcinoma [ 1 ]. (cdlib.org)
  • Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates? (biomedcentral.com)
  • Sporadic renal cell carcinoma (RCC) is rare in young adults. (biomedcentral.com)
  • Renal cell carcinoma (RCC) is the most common renal parenchymal malignancy and represents 3% - 6% of all adult malignancies [ 1 ]. (biomedcentral.com)
  • Identification of 3 genomic regions associated with squamous cell lung carcinoma. (nebula.org)
  • Squamous cell lung carcinoma (SCLC) is a type of lung cancer caused by mutations in squamous cells that line the airways of the lungs. (nebula.org)
  • Objective: To determine the outcome of superficial RTx of cSCC in correlation to histological differentiation grade and tumor localization. (uzh.ch)
  • For example, the epithelial−mesenchymal transition phenotype presents more cells with a lower degree of differentiation and greater cell dissociation in the ITF than in other tumor areas 14 , 15 . (nature.com)
  • Large cell neuroendocrine carcinoma (LCNEC) is now recognized as a histologically high grade non small cell carcinoma showing histopathological features of neuroendocrine differentiation as well as immunohistochemical neuroendocrine markers. (ersjournals.com)
  • Finally, a new class was defined called carcinoma with pleomorphic, sarcomatoid, or sarcomatous elements, which brings together a number of proliferations characterized by a spectrum of epithelial to mesenchymal differentiation. (ersjournals.com)
  • It shows significant acinar cell differentiation but also ductal, mesenchymal and neuroendocrine differentiation. (orpha.net)
  • Since physical signals sensed by cells, such as the mechanical properties of the matrix (local rigidity, adhesiveness, architecture, etc.) are increasingly emerging as determinants of cell survival, proliferation, migration and differentiation, we intend to examine the influence of the physical and mechanical properties of nano- and micro-patterned substrates on cell adhesion. (studylibfr.com)
  • However, the proportion of neuroendocrine differentiation was found to be much higher in follow-up studies and it is now thought that 50% to 100% of all prostate neoplasms (including benign prostatic tissue) contain at least some neuroendocrine cells [3,5]. (cancernetwork.com)
  • There are two accepted theories of their origin: remnants of dental lamina and proliferation of cells from the basal layer of oral epithelium into the mandible or maxilla. (bvsalud.org)
  • Basal cell nevus syndrome. (bvsalud.org)
  • Small odontogenic keratocysts, usually asymptomatic, are often discovered only during radiographic examination 4,6 and may also be associated with basal cell nevus syndrome, also known as Gorlin-Goltz syndrome 4,7-9 . (bvsalud.org)
  • The two major types of NMSC, basal cell (BCC) and squamous risk factor data [8,9,24,30]. (cdc.gov)
  • Metastatic contaminations, for example, liver and cell breakdowns in the lungs, influence a larger part of patients with harmful chest development. (hilarispublisher.com)
  • Based on these findings, metastatic carcinoma was suspected. (e-acfs.org)
  • Combined with observations of neuroendocrine enrichment in cases of poor clinical response to androgen deprivation therapy, these findings support the notion that the clonal expansion of AR-negative neuroendocrine cells may play a critical role in the development of androgen-insensitive metastatic prostate cancer. (cancernetwork.com)
  • Since the formation of the metastatic lesion occurs via clustered CTC rather than through single CTC ( Nature 514(7522) (2014)">4 , Cell 158(5) (2014)">5 ), it is possible to control recurrence if a strategy targets clustered CTCs. (cancerdiagnosisprognosis.org)
  • Heterogeneous Tumor-Immune Microenvironments between Primary and Metastatic Tumors in a Patient with ALK Rearrangement-Positive Large Cell Neuroendocrine Carcinoma. (go.jp)
  • atypical adenomatous hyperplasia and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. (ersjournals.com)
  • In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
  • The risk of the emergence of pulmonary metastasis of renal carcinoma after surgery has been estimated between 30 and 40 percent, with average delay of 15 months [ 1 ]. (cdlib.org)
  • We present a case of pulmonary metastasis from renal carcinoma with subcutaneous implantation of tumor cells along the needle tract after percutaneous needle biopsy of the lung. (cdlib.org)
  • prise about 4% of cancers in women, invasive squamous-cell carcinoma. (who.int)
  • A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
  • An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST. (lookformedical.com)
  • Using high-resolution time-lapse intravital imaging, tumor cell migration in the tumor core, border and invasive front was recorded. (nature.com)
  • Two types of border configurations contributed to tumor cell spreading through distinct invasion patterns: an invasive margin that executes slow but directed invasion, and a diffuse infiltration margin with fast but less directed movement. (nature.com)
  • To further investigate the physiological processes 40 underlying GBM cell movement, this study aimed to image and analyze distinct GBM invasive growth patterns found in vivo , similar to those observed in patients. (nature.com)
  • Invasive lobular carcinoma (ILC) is the second most frequently occurring histological breast cancer subtype after invasive ductal carcinoma (IDC), accounting for around 10% of all breast cancers. (lu.se)
  • Reclassified in 2005 by the World Health Organization as a benign tumor, odontogenic keratocyst is an intraosseous lesion of the maxilla with a destructive and invasive behavior, high recurrence rate (25% to 62.5%), and specific histological aspects 1 . (bvsalud.org)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • Endoscopic ultrasound-guided biopsy revealed poorly differentiated neuroendocrine carcinoma of the esophagus with metastasis to a diaphragmatic lymph node. (biomedcentral.com)
  • Here, we describe the case and management of a previously healthy 67-year-old male in his fifth year of remission after treatment for poorly differentiated large cell neuroendocrine carcinoma of the esophagus. (biomedcentral.com)
  • Differential diagnoses include poorly differentiated adenocarcinomas, solid pseudopapillary tumors, pancreatic carcinoma, pancreatic neuroendocrine tumors and autoimmune pancreatitis. (orpha.net)
  • The increased levels of EphA2 and EphrinA-1 in a relative high number of early stage squamous cell carcinomas suggested that these two proteins may play an important role in the development of a subset of early cervical cancers. (medsci.org)
  • Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR), including gefitinib and erlotinib, have become the standard first-line therapy for patients with advanced non-small cell lung cancers (NSCLCs) harboring activating EGFR mutations ( 4 , 5 ). (spandidos-publications.com)
  • Lung flooding was performed in four human lung lobes which were resected from non-small cell lung cancers. (biomedcentral.com)
  • Large cell neuroendocrine carcinoma (LCNEC) is a rare type of lung cancer that accounts for approximately 3% of lung cancers. (e-acfs.org)
  • Large cell neuroendocrine carcinoma (LCNEC) is a rare subtype of lung cancer, accounting for 1% to 3% of all lung cancers, and is known for its aggressive behavior [ 1 ]. (e-acfs.org)
  • The largest associations were for patients with early-stage non-small cell cancers, particularly adenocarcinomas. (bmj.com)
  • Patients with lung cancer, with higher average ambient NO 2 , PM 2.5 and PM 10 exposures since diagnosis, had shorter survival, with the largest differences in survival for patients with early-stage non-small cell cancers (particularly adenocarcinomas). (bmj.com)
  • A novel form of copper-dependent and reactive oxygen species (ROS)-dependent cell death, cuproptosis, has been described in many cancers. (biomedcentral.com)
  • The estimated association with secondhand smoke exposure was greater for small cell lung cancer than for nonsmall cell lung cancers (OR=2.11, 95% CI: 1.11-4.04). (elsevierpure.com)
  • La présente étude a estimé les fréquences relatives du cancer de la cavité buccale et du pharynx chez des patients yéménites atteints de cancers enregistrés en 2007 et 2008. (who.int)
  • High-risk types (e.g., types 16 and 18) can cause low-grade cervical cell abnormalities, high-grade cervical cell abnormalities that are precursors to cancer, and cancers ( 5 - 7 ). (cdc.gov)
  • By using immunohistochemistry we investigated the expression of EphA2 and EphrinA-1 in 217 early squamous cell cervical carcinomas and examine their prognostic relevance. (medsci.org)
  • To overcome tumor cell resistance and uncover new and efficient prognostic biomarkers for HNSCC, it is particularly important to investigate other forms of cell death. (biomedcentral.com)
  • The remaining 44% were composed of carcinomas not otherwise specified and a variety of uncommon tumors: large cell, clear cell, solid, bronchoalveolar, adenosquamous, epithelial hemangioendothelioma, oat cell, carcinoid, small cell and mucinous histological types. (biomedcentral.com)
  • As cytomorphological appearance was consistent with anaplastic carcinoma in ultrasonography-guided aspiration biopsies of thyroid nodule and lymphadenopathy, immunohistochemical staining was performed for differential diagnosis of lymphoma. (endocrine-abstracts.org)
  • At the time of TCL diagnosis, Anaplastic large-cell lymphoma (ALCL) was the most common TCL subtype within PWH. (cdc.gov)
  • LCNEC is often generically grouped among the non-small-cell lung carcinomas. (wikipedia.org)
  • The World Health Organization classification of lung tumors recognizes a variant of LCNEC, namely "combined large-cell neuroendocrine carcinoma" (c-LCNEC). (wikipedia.org)
  • Data on histological type, clinical stage, smoking status, gender and patient age were collected from medical records. (spandidos-publications.com)
  • It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA . (lookformedical.com)
  • Clinical Implications and Molecular Characterization of Drebrin-Positive, Tumor-Infiltrating Exhausted T Cells in Lung Cancer. (go.jp)
  • Breast cancer is a heterogeneous disease with a large variabil- survival after adjuvant polychemotherapy was 10% (from ity in clinical outcome. (lu.se)
  • Adjuvant polychemotherapy (e.g. with 58% to 68%) for patients under the age of 50.1 Besides an cyclophosphamide, methotrexate and 5-fluorouracil (CMF)) or improvement in clinical outcome, these figures indicate that anthracycline-containing regimes, produce substantial reduc- a large proportion of the patients will never recur after the tion in recurrence and mortality. (lu.se)
  • Clinical appearance of a lateral tongue squamous cell carcinoma in an 80-year-old man with a previous history of smoking and regular alcoholic beverage consumption. (medscape.com)
  • According to Revised European American Classification of Lymphoid Neoplasms, the diagnosis was diffuse large B-cell lymphoma. (endocrine-abstracts.org)
  • We introduce the case in order to emphasize that infiltration of diffuse large B-cell lymphoma should be recalled with instantaneous enlargement of nodules known to be benign previously, and when cytological specimen is uncertain, immunohistochemical staining should be performed for differential diagnosis. (endocrine-abstracts.org)
  • Diagnosis is based on histological characteristics. (orpha.net)
  • Thus, a diagnosis is made by skin biopsy showing a large number of yeasts of uniform size and thick cell walls that form chains linked by thin bridges that are shown by staining with methenamine silver ( 2 , 4 , 9 , 18 ). (cdc.gov)
  • Most of this classification is based on the histological characteristics of tumours seen in surgical or needle biopsy, and is primarily based on light microscopy, although immunohistochemistry and electron microscopy findings are provided when necessary. (ersjournals.com)
  • Percutaneous needle biopsy of the lung was performed via the right anterior chest wall and the histologic findings showed metastasis from renal carcinoma. (cdlib.org)
  • Unfortunately, exclusion of dysplasia in a biopsy sample does not guarantee that elsewhere in the lesion there is not dysplasia or even carcinoma. (medscape.com)
  • Cancer-associated fibroblasts (CAFs) have been demonstrated to be essential stromal components in the tumor microenvironment, regulating cancer cell growth, migration, invasion, and chemo-response through various mechanisms. (dovepress.com)
  • The latter are histologically similar to small cell or carcinoid tumors. (cancernetwork.com)
  • SCLC accounts for approximately 15% of bronchogenic carcinomas. (cancer.gov)
  • Worldwide, cervical carcinoma is the second most frequent malignancy among women and the death rate is 8 per 100,000 [ 1 ]. (medsci.org)
  • In our study 52, 64, 101, 500 and 246 PWH with histological confirmation of TCL, primary CNS, Burkitt's, diffuse large B-cell lymphoma (DLBCL) and Hodgkin's lymphoma (HL) respectively and 450 TCL without HIV were eligible for analysis. (cdc.gov)
  • It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer. (lookformedical.com)
  • The most common type of lung cancer in men is squamous cell carcinoma. (nebula.org)
  • Histological lung cancer type was only provided by 12 centers (59 cases). (biomedcentral.com)
  • Primary brain tumor initiating cell lines from IDH-wild type GBM stably expressing H2B-Dendra2 were implanted orthotopically in the brains of SCID mice. (nature.com)
  • While the association between exposure to secondhand smoke and lung cancer risk is well established, few studies with sufficient power have examined the association by histological type. (elsevierpure.com)
  • In this study, we evaluated the secondhand smoke-lung cancer relationship by histological type based on pooled data from 18 case-control studies in the International Lung Cancer Consortium (ILCCO), including 2,504 cases and 7,276 control who were never smokers and 10,184 cases and 7,176 controls who were ever smokers. (elsevierpure.com)
  • Squamous cell carcinoma is another non-small cell lung cancer type. (mesotheliomaattorneysnearme.com)
  • Small cell lung cancer is a very aggressive cancer type that affects many each year. (mesotheliomaattorneysnearme.com)
  • The univariate analyses showed that pathological stage 1B, histological type of squamous cell carcinoma, male sex, maximum tumor size over 2 cm, eSUVm, lSUVm, and MTV2.5 were associated with reduced DFS. (iiarjournals.org)
  • Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
  • We aimed to clarify the characteristics associated with HMs in lesions resected en bloc with ESD. (bvsalud.org)
  • Site-specificity of and cell proliferation would allow DPX and cell proliferation formaldehyde-induced lesions in rats and monkeys implicates data to be interpolated from measurement sites to the rest of the regional tissue susceptibility and dose as factors potentially nasal passage. (cdc.gov)
  • DSRCT is composed of small cells with round hyperchromatic nuclei and a dense fibrous or spindle cell stroma. (medscape.com)
  • However, even these patients are at risk of dying from lung cancer (both small and non-small cell types). (cancer.gov)
  • Histologic sections show small nests of cytologically bland epithelial cells with abundant clear to eosinophilic cytoplasm distributed within a fibromatous stroma. (cap.org)
  • The epithelial cells have a urothelial cell-like appearance, with abundant clear to pale eosinophilic cytoplasm and small nucleoli. (cap.org)
  • The presence of neoplastic islands, classified as large or small according to the number of cells in the ITF, has been described as the most aggressive pattern compared to tumors with a more uniform growth pattern, as tumor invasion occurs in a more widespread manner as cellular islands or single cells 4 . (nature.com)
  • Conversely, treatment for small cell lung cancer remains chemotherapy-based and whilst there are promising results with novel cytotoxics, its platinum-etoposide backbone holds strong ( 2 ). (amegroups.org)
  • Recent evidence indicates that endothelialization of bypass grafts by establishment of a confluent and stable endothelial cell layer in the lumen of vascular grafts is critical for longterm patency of small-diameter vascular grafts. (studylibfr.com)
  • Small-cell carcinomas are stimulated by bombesin/GRP and related peptides and contain receptors for them. (cancernetwork.com)
  • Our study provides more precise estimates of the impact of secondhand smoke on the major histological types of lung cancer, indicates the association with secondhand smoke is stronger for small cell lung cancer than for the other histological types, and suggests the importance of intervention against exposure to secondhand smoke in lung cancer prevention. (elsevierpure.com)
  • Those categories are non-small cell lung cancer and small cell lung cancer. (mesotheliomaattorneysnearme.com)
  • In this article we are going to take a look at traditional lung cancer types: non-small cell lung cancer and small cell lung cancer. (mesotheliomaattorneysnearme.com)
  • Non-small cell lung cancer is responsible for the majority of lung cancer cases in the United States. (mesotheliomaattorneysnearme.com)
  • Non-small cell lung cancer is an umbrella term that includes a variety of different cancer types. (mesotheliomaattorneysnearme.com)
  • Small cell lung cancer is a very unique cancer in that it has the possibility of producing ectopic hormones. (mesotheliomaattorneysnearme.com)
  • The two most common hormones secreted by small cell lung cancer includes both ACTH and ADH. (mesotheliomaattorneysnearme.com)
  • Histological examination revealed a combined lung tumor appearance with a predominant component (80%) consisting of a small cell neuroendocrine carcinoma associated with a solid adenocarcinomatous component, with massive infiltration of the lung, rupture of the visceral pleura, and extension to parietal fat tissue but with free surgical margin at this level and without sarcomatoid component. (hindawi.com)
  • Histological examination showed Large cell non keratinizing squamous cell carcinoma. (jebmh.com)
  • However, an initial pathological examination revealed intradermal-cord-like tumor invasion, with histological features similar to those of lung tumors with lymphovascular invasion ( Fig. 2 ). (e-acfs.org)
  • Histological examination of the surgical specimen revealed clear cell renal carcinoma pT2 N0. (cdlib.org)
  • Pathologic examination revealed a pT2 undifferentiated carcinoma with a sarcomatoid component involving all layers of the jejunum and expressing only cytokeratin 7. (hindawi.com)
  • 1]. World Health Organization Histological Classification of Lung and Pleural Tumours. (wikipedia.org)
  • High-intensity focused ultrasound with lung flooding produced a thermal effect in an ex vivo human lung carcinoma and in vivo simulated lung tumours in a porcine model. (biomedcentral.com)
  • Circulating tumour cells (CTCs) are tumour cells found in the peripheral circulating blood, of which clustered CTCs has high potential to develop into recurrent tumours ( Nature 514(7522) (2014)">4 ). (cancerdiagnosisprognosis.org)
  • Computed tomography (CT) guided aspiration cytology showed atypical cells. (urotoday.com)
  • While normal thyrocytes were detected in thyroid gland, atypical lymphoid cells showing diffuse infiltration in thyroid tissue were observed in the nodule, which were stained diffuse, strongly positive for CD20 and BcL and negative for CD45 RO. (endocrine-abstracts.org)
  • In the lymph node, diffusely infiltrating atypical lymphoid cells with similar immunohistochemical staining properties were observed. (endocrine-abstracts.org)
  • Borderline/atypical proliferative Brenner tumors are often larger than benign Brenner tumors, with an average diameter of 18 cm. (cap.org)
  • SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
  • Objectives: Endoscopic submucosal dissection (ESD) enables en bloc resection of colorectal neoplasms, but occasionally results in positive horizontal margins (HMs). (bvsalud.org)
  • Methods: Patients with colorectal neoplasms who underwent en bloc resection with ESD were included in this study. (bvsalud.org)
  • Standardized guidelines for the treatment of these neoplasms remain lacking as the rarity of these tumors hinders the development of large cohort studies that provide evidence-based recommendations. (biomedcentral.com)
  • Laminin 5 (Ln5) is an extracellular matrix protein that plays an important role in cell migration and tumor invasion. (spandidos-publications.com)
  • 11 Chemoresistance, either acquired or intrinsic, is associated with a complicated and multifactorial process, including decreases of intracellular drugs, changes of drug targets, aberrant regulation of cell survival or death, and crosstalks between tumor microenvironment and cancer cells. (dovepress.com)
  • The normal function of EphA2 is not fully understood, but it is thought to function in the regulation of cell growth, angiogenesis, survival and migration [ 9 - 11 ]. (medsci.org)
  • In our previous study of cervical carcinomas FIGO stage I-IV we found that increase expression of EphA2 and EphrinA-1 was significantly associated with shorter overall survival in multivariate analysis [ 22 ]. (medsci.org)
  • Here, we review the literature and report a unique case of a patient with a vague presentation of esophageal neuroendocrine carcinoma as he enters his sixth year of survival following neoadjuvant chemoradiotherapy. (biomedcentral.com)
  • Data obtained from patients with androgen- independent prostatic carcinoma have revealed that prostate-specific antigen (PSA) correlates with survival in patients with normal bombesin levels. (cancernetwork.com)
  • Squamous cell carcinoma of the head and neck is the sixth most common cancer worldwide, and the 5-year survival rate is less than 50% despite surgery [ 1 ]. (biomedcentral.com)
  • We investigated the relationship of survival with tumor size and histological sub-groups, levels of lactate dehydrogenase (LDH) and hemoglobin(Hb), weight loss, performance status, age, and gender. (hasekidergisi.com)
  • The report also found the estimated 1-, 5-, and 10-year relative survival rates for squamous cell carcinoma of the oral tongue to be greater in white women than in African American females, but following multivariable analysis, the investigators attributed the higher survival rate not to race but to such factors as lower stage, younger age, married status, and receipt of surgical treatment. (medscape.com)
  • Background: Surgical excision is the gold standard for cutaneous squamous cell carcinoma (cSCC), however its application is limited in specific cases. (uzh.ch)
  • A study by Joseph et al found that the incidence of squamous cell carcinoma of the oral tongue has risen among white females in the United States while at the same time decreasing among African American women. (medscape.com)
  • We had the opportunity to elucidate the risk of SCC incidence and 80% in BCC incidence were documented multiple malignancies using a large population-based series of among both males and females over 14 years [4]. (cdc.gov)
  • We have performed a comprehensive genomic, transcriptomic and proteomic analysis of a large ILC patient cohort and present here an integrated molecular portrait of ILC. (lu.se)
  • Microscopically, the tumors are composed of solid to cystic nests of epithelial cells embedded in a fibrous stroma. (cap.org)
  • A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. (lookformedical.com)
  • alveolar and bronchial epithelial cells in tumor-adjacent tissues were negative for Oct-4 staining (Figure 1). (vegfinhibitors.com)
  • Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)