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  • Mucinous
  • Microscopic characteristics of rhabdoid cells include: Oval to polygonal cell shape Eosinophilic, hyaline-like perinuclear agglomerations of intermediate filaments Compressed, eccentric nuclei Prominent central macronucleoli (one or two) Abundant eosinophilic cytoplasm Reticular chromatin pattern The differential diagnosis of LCLC-RP includes secondary metastatic lesions, melignant melanoma of the lung with rhabdoid phenotype, mucinous adenocarcinomas (particularly those featuring signet-ring cells), rhabdomyosarcoma, epitheloid angiosarcoma, pleural mesothelioma, and plasmacytoma. (wikipedia.org)
  • In 1870 Gusserow was the first physician to describe a rare type of uterine cervical adenocarcinoma that is sometimes referred to as "adenoma malignum" or as a mucinous type of "minimal deviation adenocarcinoma" (mucinous MDA). (wikipedia.org)
  • Informally, some experts have included these tumors as a distinct variant among a spectrum of mucus-producing adenocarcinomas, including - in order of increasing relative extent of cellular mucus production and extracellular mucus accumulation - solid adenocarcinoma, mucoepidermoid carcinoma, mucinous bronchioloalveolar carcinoma, signet ring cell adenocarcinoma, mucinous cystadenocarcinoma, and mucinous "colloid" adenocarcinoma. (wikipedia.org)
  • Microscopically, the neoplastic epithelial cells tend to grow along the alveolar walls, in a fashion similar to the mucinous variant of bronchioloalveolar carcinoma, a more common form of adenocarcinoma. (wikipedia.org)
  • lesions
  • About 2.5% of the samples, exclusively from benign lesions and with a positive histological diagnosis, showed negative molecular results for both primers. (scielo.br)
  • clarification needed] Deeper inhalation of cigarette smoke results in peripheral lesions that are often the case in adenocarcinomas of the lung. (wikipedia.org)
  • Differentiation
  • Some results indicate that histological grade and NE differentiation seen in prostatectomy samples predicted progression in multivariate analysis or disease specific survival . (chsjournal.org)
  • patients
  • The European Society of Parenteral and Enteral Nutrition recommend PN only for malnourished subjects but does not reflect situation in cancer cachexia patients At present, no 2nd-line therapy (or higher) is recommended for pancreatic adenocarcinoma, but often asked for. (clinicaltrials.gov)
  • Because of the asymmetric increase in treatment options for adenocarcinoma and the absence of data for specific systemic agents in the NCDB, this histology-based difference was consistent with our hypothesis that treatment within ACs has conferred a survival advantage for patients with NSCLC following the introduction of novel targeted therapies that require a molecularly-driven, histologically-specific approach. (medicalxpress.com)
  • risk of adenocarcinoma
  • Exposure to wood and leather dusts increases the risk of adenocarcinoma by 500-fold [ 8 , 9 ]. (hindawi.com)
  • According to the Nurses' Health Study, the risk of adenocarcinoma of the lung increases substantially after a long duration of previous tobacco smoking, with a previous smoking duration of 30 to 40 years giving a relative risk of approximately 2.4 compared to never-smokers, and a duration of more than 40 years giving a relative risk of approximately 5. (wikipedia.org)
  • glands
  • Cholangiocarcinoma is a relatively rare neoplasm that is classified as an adenocarcinoma (a cancer that forms glands or secretes significant amounts of mucins). (wikipedia.org)
  • Adenocarcinomas can arise in many tissues of the body owing to the ubiquitous nature of glands within the body, and, more fundamentally, to the potency of epithelial cells. (wikipedia.org)
  • Grading
  • For soft-tissue sarcoma two histological grading systems are used : the National Cancer Institute (NCI) system and the French Federation of Cancer Centers Sarcoma Group (FNCLCC) system. (wikipedia.org)
  • prevalence
  • Although the level of disagreement for histological type observed in this study is comparable with that in other studies, the resulting misclassification would lead to the reduction in observed differences in prevalence and odds ratio estimates between two histological types. (aacrjournals.org)
  • Findings
  • Data collected included patient age, duration of lower urinary tract symptoms and hospitalisation, findings on digital rectal examination, prostate volume, haemoglobin concentration, serum creatinine and prostate-specific antigen (PSA) levels, and histological findings. (scielo.org.za)
  • molecular
  • To examine the differences in risk factors and molecular changes between the histological types, reliable data on histological typing are essential. (aacrjournals.org)
  • Investigators have examined risk factors and molecular changes that might be differentially associated with various histological types. (aacrjournals.org)
  • Nas amostras de lesão benigna e adenocarcinoma gástrico, a infecção foi detectada em 43% (42/98) e 71% (70/98), respectivamente, para os diagnósticos histológico e molecular (p = 0,0001). (scielo.br)
  • Diferenças estatisticamente significantes foram encontradas entre os métodos histológico e molecular, em metaplasia intestinal (p = 0,0461) e adenocarcinoma gástrico (p = 0,0011), devido à subdetecção do H. pylori pelo método histológico, e provavelmente pela baixa densidade da bactéria conseqüente à atrofia severa da mucosa gástrica, nesses dois tipos de lesões. (scielo.br)
  • Highly
  • Highly differentiated adenocarcinomas form SRCCs via a loss of adherens and tight junctions that typically separate MUC4, a mucin protein, and ErbB2, an oncogenic receptor. (wikipedia.org)
  • form
  • While each gland may not be secreting the same substance, as long as there is an exocrine function to the cell, it is considered glandular and its malignant form is therefore named adenocarcinoma. (wikipedia.org)
  • uses
  • The gastroenterologist uses a colonoscopy to find and remove these adenomas and polyps to prevent them from continuing to acquire genetic changes that will lead to an invasive adenocarcinoma. (wikipedia.org)