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  • Lymphoma
  • Classical Hodgkin lymphoma, which is very rare in the skin, is distinguished by the presence of Reed-Sternberg cells and mononuclear variants, which are large malignant cells with eosinophilic macronucleoli and have the following immunophenotype: CD15+, CD30+ (the first 2 with a membranous pattern of staining and Golgi accentuation), CD45-, and weakly nuclear Pax-5 positive. (psychiatryadvisor.com)
  • In this month's issue, Schein and associates (p. 417) report on their successful experience with BACOP (bleomycin, Adriamycin┬«, cyclophosphamide, Oncovin┬« [vincristine], and prednisone) combination chemotherapy in the management of patients with advanced histiocytic lymphoma. (annals.org)
  • The data of Schein and colleagues at the National Cancer Institute add substantially to the notion that malignant lymphoma, histiocytic diffuse type-once an invariably fatal disorder-is now a very treatable and perhaps curable disease. (annals.org)
  • Histiocytoma is readily distinguished from other histiocytic disorders and cutaneous lymphoma with the aid of IHC. (wikipedia.org)
  • disease
  • The Histiocyte Society, a nonprofit organization, is a group of more than 200 physicians and scientists from around the world committed to improving the lives of patients with histiocytic disorders by conducting clinical and laboratory research into the causes and treatment of this disease. (wikipedia.org)
  • commonly
  • Malignant endothelial cells also commonly retain the antigen, so that CD31 immunohistochemistry can also be used to demonstrate both angiomas and angiosarcomas. (wikipedia.org)
  • body
  • In this example, malignant means something that spreads throughout the body in an uncontrolled fashion. (petmd.com)