• In vivo vMSOT brain imaging of P301L mice showed higher retention of PBB5 in the tau-laden cortex and hippocampus compared to wild-type mice, as confirmed by ex vivo vMSOT, epi-fluorescence, multiphoton microscopy, and immunofluorescence staining. (springer.com)
  • Much of this improvement was due to limiting the analyses to the posterior limb of the internal capsule, thalamus, parietal cortex, hippocampus, and medulla. (ajnr.org)
  • Immunohistochemistry revealed a marked increase in extracellular clusterin protein expression in the perilesional cortex and ipsilateral hippocampus (7d to 1 month post-TBI), and ipsilateral thalamus (14d to 12 months post-TBI). (nature.com)
  • By thoroughly overviewing previous findings, we hypothesized that meditation reduces pain-related neural activity in the ACC, insula, secondary somatosensory cortex, and thalamus. (frontiersin.org)
  • This is because the thalamus, a part of the limbic system, still carries on its function of relaying sensory signals to the front of the brain to the prefrontal cortex during trauma. (steamboatpilot.com)
  • If, however, the animal is alerted desynchronization (fast low waves) is observed in the cortex and desynchronization (high 4-6 c/s waves) in the thalamus and hippocampus. (erowid.org)
  • LSD (20 mcg/kg i.v.) produces pronounced alerting in the EEG with desynchronization of the cortex and hypersynchronization of the hippocampus [thalamus not traced]. (erowid.org)
  • We found that exposure to WIN 55,212-2 significantly reduced BDNF levels in hippocampus and frontal cortex. (researchgate.net)
  • In particular, prenatal cannabinoid treatment reduced the phosphorylated levels of ERK1/2 in selected subcellular compartments of hippocampus, frontal and prefrontal cortex, whereas no changes were observed in the total levels of these proteins. (researchgate.net)
  • They then travel to the piriform cortex where they propagate further downstream to the hippocampus and modulate neural processes critical for memory formation. (mpi.nl)
  • Using chemogenetics and microdialysis, we show that, in sign-trackers, stimulation of the neuronal pathway from the prelimbic cortex (PrL) to the paraventricular nucleus of the thalamus (PVT) decreases the incentive value of a reward-cue. (elifesciences.org)
  • The hippocampus likely allows long-term memory encoding in the cortex and allows short-term memory retrieval. (medscape.com)
  • Overall, levels of these lipids were significantly lower among paced compared to standard mated rats with the most dramatic decreases observed in brainstem, hippocampus, midbrain, and striatum. (hindawi.com)
  • We now aim to determine whether exposure to neonatal pain-related stress (adjusted for clinical factors) deferentially impacts regional structures within the limbic system and thalamus and investigate relationships with outcomes in very preterm children. (ubc.ca)
  • The hippocampus serves as a primary output structure of the limbic system. (medscape.com)
  • Subtantia Nigra styrker det inhibitoriske signalet Striatum sender på Globus palladus, slik at Globus palladus svekker den inhibitorisek effekten på thalamus i enda større grad. (flashcardmachine.com)
  • Histopathological studies identified a distinct pattern of acute injury to subcortical motor pathways that involved the basal ganglia and thalamus. (jneurosci.org)
  • Uterine ischemia in the dams resulted in a distinct neurobehavioral phenotype in the newborn pups, which was characterized by an increase in forelimb tone that was significantly correlated with histological evidence of persistent injury to subcortical motor pathways involving the basal ganglia and anterior thalamus. (jneurosci.org)
  • The thalamocingulate radiation then projects to the cingulate gyrus and back to the hippocampus to complete the circuit. (medscape.com)
  • From the hippocampus, signals are relayed via the fornix to the mammillary bodies and via the mammillothalamic tract to the anterior nucleus of the thalamus. (medscape.com)
  • As part of this circuit, the mammillary bodies play a particular role in spatial memory with connections to other regions important to memory: the hippocampus and anterior thalamus. (lu.se)
  • Persistent injury to the caudate putamen and thalamus at P1 was significantly correlated with hypertonic motor deficits in the hypoxic group. (jneurosci.org)
  • Serum CRP significantly mediated the effect of liver fibrosis on most cognitive measures and regional GMVs in the hippocampus and brain stem. (medscape.com)
  • However, chamber exposed rats had significantly higher levels of these lipids compared to home cage controls and paced mated wherein the hippocampus showed the largest increases. (hindawi.com)
  • Hemodynamic activity in the somatosensory and motor cortices and in the hippocampus and thalamus increased during penile stimulation, and thalamic activation was linearly dependent on self-reported sexual arousal. (snmjournals.org)
  • Stress inhibits neurogenesis in the hippocampus, and neonatal stress/noxious stimulation in rodent pups are associated with long-term alterations in hippocampal volumes. (ubc.ca)
  • Furthermore, a robust reduction of total and phospho-alpha-CaMKII was found in the hippocampus of rats prenatally exposed to WIN 55,212-2. (researchgate.net)
  • The hippocampus is felt to be a structure that is crucial to formation of memory--more specifically, a type of memory called declarative or explicit memory. (medscape.com)
  • In laboratory studies of animals and humans, the hippocampus has been shown to also have a cellular memory termed "long-term potentiation. (medscape.com)
  • Moreover, we found comparable medium effect sizes for group-related comparison of the thalamus in the two analytical methods. (unibas.ch)
  • Severe injury to the hippocampus can be devastating to the injured person's lifestyle because all of their previous experiences would no longer have any 'meaning' to them. (seriousinjurylaw.co.uk)