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  • neuronal
  • A remarkable finding regarding the influence of stress on the brain is that the stress response can result in neurodegeneration [ 10 ], including decreased brain volume, neuronal atrophy, and decreases in synaptic proteins [ 11 ]. (beds.ac.uk)
  • However, not much is known about how CREB-dependent neuronal alterations in synaptic strength, excitability and LTP can boost memory formation in the complex architecture of a neuronal network. (yale.edu)
  • increases
  • Of the recently reported findings on the molecular mechanisms associated with synaptogenesis, increases in synaptic protein levels after the activation of mammalian target of rapamycin complex 1 (mTORC1) signaling are of particular importance [ 13 ]. (beds.ac.uk)
  • Though there is not adequate information to determine the exact mechanism of action for Sunifiram, its association with the glutamate level in the brain, presumably, increases the energy level in the user. (nootriment.co)
  • events
  • Further, the detection algorithm for distinguishing photo-induced events from background events was tested and proven to be capable of faithfully differentiating between the two kinds of photo-induced events - the direct responses and the synaptic inputs. (fu-berlin.de)
  • software
  • By mapping the intralaminar synaptic connectivity of Layer 2 stellate cells (L2S) of the mEC as a model cell, the applicability, resolution and repeatability of the software was validated. (fu-berlin.de)
  • results
  • The results are robust and consistent upon increasing the synaptic damage expected by AD progression, supporting the idea that the use of CREB-based therapies could provide a new approach to treat AD. (yale.edu)