As the glyoxylate cycle is an important pathway in the utilization of alternative carbon sources, we also highlight the key metabolic enzymes in the glyoxylate cycle and its necessity for the pathogenesis of C. glabrata . (biomedcentral.com)
Results highlight2
Overall, these results highlight the complex nature of organic matter transformation in NRZs and the microbial metabolic pathways that interact to mediate redox status and elemental cycling. (frontiersin.org)
The results highlight the utility of metapangenomic approaches employed across environmental gradients, to decipher the properties and variation in function and ecological traits of specific phylogenetic clades within complex microbiomes. (biomedcentral.com)
Mitochondrial2
Here, we review the biosynthetic roles of mitochondrial metabolism in tumors and highlight specific cancers where these processes are activated. (biomedcentral.com)
Although many of these functions are similarly important in normal, proliferating cells, we have attempted to highlight potential points where mitochondrial metabolism may be therapeutically targeted to slow cancer growth. (biomedcentral.com)
Target2
Another project will target isocitrate lyase, which is known to be important for M. tuberculosis survival. (bioedonline.org)
Descriptions of the IDG illumination levels, highlighting the milestones attained in research for this target. (nih.gov)
Levels1
gene expression measurements showed increases in mRNA levels for two complex II subunits and for isocitrate lyase, the key glyoxylate pathway enzyme. (nih.gov)
Growth1
Collectively, these data expand the current models of RSK signalling and highlight potential directions of research in RSK-mediated survival, growth, proliferation and migration. (xcessbio.com)