• While many studies have focused on measuring ultrafine particle (UFP) concentrations in environments where children are at risk of high exposure, few studies have examined the particle deposition in the respiratory tract of children. (cdc.gov)
  • From granular assessment of each street-level address to identifying key climate risk concentrations in huge portfolios. (munichre.com)
  • Exposure to SHS was measured by plasma cotinine concentrations. (harvard.edu)
  • Autoimmune disorders such as rheumatoid arthritis and lupus have been found to occur more frequently in Libby than would normally be expected, and antibody levels to the body's own tissues are found in Libby residents more frequently and at higher concentrations. (isu.edu)
  • They reported that diet was likely a major source of glyphosate and AMPA exposure among study participants, as indicated by higher urinary glyphosate or AMPA concentrations among those adolescents who ate more cereal, fruits, vegetables, bread, and in general, carbohydrates. (non-gmoreport.com)
  • The researchers found that young children were exposed to even higher concentrations of air pollution during peak morning periods at urban pollution hotspots, such as traffic lights. (surrey.ac.uk)
  • Taking measurements on over 80 runs covering 176km, the researchers assessed the differences in exposure concentrations on the bike compared within the trailer. (surrey.ac.uk)
  • Compared with G2s, G3 devices delivered significantly higher power to the atomiser, but G3 users vaped e-cigarette liquids with significantly lower nicotine concentrations. (bmj.com)
  • During the vaping session, G3 users achieved significantly higher plasma nicotine concentrations than G2 users following the first 10 puffs (17.5 vs 7.3 ng/mL, respectively) and at 25 and 40 min of ad libitum use. (bmj.com)
  • There are six long-term studies available on antimony toxicity to invertebrates which included analytical confirmation of the exposure concentrations but, as stated above, only the study by Moser (2007), which results in a bounded NOEC of 999 mg Sb/kg dw, will be used for the derivation of a PNEC soil . (europa.eu)
  • [9] [11] Persistent chemicals tend to have higher concentrations and are eliminated more slowly. (wikipedia.org)
  • Filling this knowledge gap is especially important to properly assess the risks associated with the consumption of food containing high levels of acrylamide. (cdc.gov)
  • It also poses risks to human health - both indirectly through the consumption of contaminated food and drinking water, and directly through exposure to contaminated soil. (europa.eu)
  • Business leaders from around the world have ranked the risks with the highest impact on their company success in the coming 10 years. (munichre.com)
  • In an increasingly globalised economy, it is becoming more and more difficult for you and your company to keep track of the geographical distribution of your value chain in order to assess the spread of risks and to be able to take early countermeasures if necessary. (munichre.com)
  • with Location Risk Intelligence Platform, the solution for assessing and managing physical risks from natural hazards and climate change. (munichre.com)
  • Information is given on sources of depleted uranium exposure, the likely routes of acute and chronic intake, the potential health risks from both the radiological and chemical toxicity standpoints and future research needs. (who.int)
  • For example, scientists at ATSDR have worked in more than 900 communities across the nation to assess and explain the health risks involved in exposures to hazardous substances and educate community members so they can keep their families safe. (cdc.gov)
  • Another of the three programs will focus on particular risks of exposure to Libby asbestos during childhood, when lungs are still developing and maturing. (isu.edu)
  • Accurate measurements of noise exposure and hearing protector fit should improve the ability to model and assess the risks of noise-induced hearing loss. (cdc.gov)
  • Businesses are increasingly challenged to promptly and effectively identify, assess and manage rapidly changing risks, including exposure to litigation, regulation and enforcement. (osler.com)
  • Levels of urine nickel, measured by inductively coupling plasma-emission spectroscopy, were significantly higher in nickel-exposed workers compared with the reference group. (who.int)
  • The levels of alanine aminotransferase and aspartate aminotransferase were significantly higher in nickel-exposed workers. (who.int)
  • The level of serum albumin was significantly negatively correlated and the levels of serum aminotransferases, and serum gamma-glutamyl-transpeptidase were significantly positively correlated with urine nickel levels. (who.int)
  • Cosmic particle flux is significantly higher on board aircraft that at ground level. (radioprotection.org)
  • There was a significantly higher association between all-cause and CVD-associated mortality for those in the lowest and highest quintiles of circulating vitamin C (U-shaped relationship curve). (naturalmedicinejournal.com)
  • UA producers were distinguished by a significantly higher gut microbiome diversity and ratio of Firmicutes to Bacteroides. (nature.com)
  • 0.0001) or level of exposure (p = 0.02) were significantly associated with asbestosis. (ersjournals.com)
  • Introduction Electronic cigarettes' (e-cigarettes) viability as a public health strategy to end smoking will likely be determined by their ability to mimic the pharmacokinetic profile of a cigarette while also exposing users to significantly lower levels of harmful/potentially harmful constituents (HPHCs). (bmj.com)
  • Compared with cigarettes, G2 and G3 e-cigarettes resulted in significantly lower levels of exposure to a potent lung carcinogen and cardiovascular toxicant. (bmj.com)
  • Prenatal SSRI exposure significantly increased serum CBG levels in neonates after vaginal delivery (p ≤ 0.038), even when controlling for maternal depression. (unboundmedicine.com)
  • Neonatal serum cortisol levels did not vary with SSRI exposure or antenatal maternal mood, but were significantly higher following vaginal delivery (p ≤ 0.003). (unboundmedicine.com)
  • However, prevalence of cough was significantly higher among welders compared with controls and lung changes were found in welders with the novel methods. (lu.se)
  • Welders had significantly higher respiratory system resistance assessed with oscillometry, serum levels of metalloproteinases 9 and hepatocyte growth factor, compared with controls. (lu.se)
  • [ 18 ] For instance, VDBP levels were significantly lower in blacks than in whites when using the monoclonal antibody immunoassay, whereas no racial differences were detected when using polyclonal antibody immunoassay or proteomics. (medscape.com)
  • Positive findings were mostly confined to occupational exposure to specific groups of pesticides or particular groups of those exposed. (bmj.com)
  • Findings indicate that the neurocognitive task appearing most sensitive to identifying performance change is the DANA Procedural Reaction Time (PRT) subtask which may involve a sufficient level of challenge to reliably detect a small, transient cognitive impairment among a healthy undiagnosed population. (frontiersin.org)
  • BACKGROUND: Few studies have directly assessed the association of secondhand smoke (SHS) with cardiovascular disease-related inflammatory markers, and the findings are inconsistent. (harvard.edu)
  • No treatment-related findings were observed due to xylitol exposure in any end point examined. (nih.gov)
  • This section of the zero pollution monitoring assessment presents available knowledge and trends on soil pollution and associated impacts on health, and assesses progress towards achieving relevant zero pollution targets and policy objectives. (europa.eu)
  • Idaho State University to help Mount Sinai School of Medicine assess health impacts of asbestos contamination in Libby, Mont. (isu.edu)
  • OBJECTIVES: The study was to determine how e-cigarette aerosol exposure, coupled with genetics, impacts cardiovascular oxidative stress in wild type ALDH2 and ALDH2*2 knock-in mice. (bvsalud.org)
  • When outbreaks occur in areas with highly mobile populations and porous borders, the risk of further spread within an outbreak area or to other locations with a connection to an outbreak area (e.g., neighboring country, countries with flight connections) is high. (cdc.gov)
  • The Agency was established by the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA, also known as Superfund) to assess the public health impact of hazardous wastes in the general environment, to identify human populations at risk, and to effect actions to prevent adverse health effects from human contact with hazardous substances. (cdc.gov)
  • In view of this, exposure to lead in populations close to hazardous waste sites continues to be a public health issue of concern. (cdc.gov)
  • Assessing sub-concussive blast effects can be difficult as they are hypothesized to be subtle and transient, especially among healthy, undiagnosed populations ( 8 ). (frontiersin.org)
  • These parameters must be included in the definition of high-risk populations for HRCT-based screening programmes. (ersjournals.com)
  • A family history-pesticide exposure interaction was also observed for a number of pesticides. (bmj.com)
  • Epidemiological studies examining the association between pesticide exposure and prostate cancer (PC) are heterogeneous, and provide inconsistent results. (bmj.com)
  • Plausible physiologic and biologic mechanisms: For example, positing that a major change in organ formation was due to late-trimester pesticide exposure would not be plausible because organogenesis would have been completed before the exposures. (medscape.com)
  • Objectives Occupational pesticide exposure is associated with a wide range of diseases, including lung diseases, but it is largely unknown how pesticides influence airway disease pathogenesis. (bmj.com)
  • Associations between pesticide exposure and 420 938 methylation sites (CpGs) were assessed using robust linear regression adjusted for appropriate confounders. (bmj.com)
  • Several of the identified genes, for example, RYR1 , ALLC , PTPRN2 , LRRC3B , PAX2 and VTRNA2-1 , are genes previously linked to either pesticide exposure or lung-related diseases. (bmj.com)
  • Millions of workers worldwide are exposed daily to occupational pesticide exposure, but it is largely unknown how pesticides influence airway disease pathogenesis. (bmj.com)
  • In addition, comparison of size-dependent regional deposition and particle concentration establishes an accurate depiction of children's exposure and dose profiles. (cdc.gov)
  • Andreas is conducting additional research to 1) assess if the chemicals have reproductive and hormonal effects in adults and 2) better understand children's exposure. (cdc.gov)
  • The researchers compared pollution in bike trailers with and without covers, finding that concerned parents and carers can reduce their children's exposure to pollutants by using a trailer cover. (surrey.ac.uk)
  • In this study, researchers analyzed data from participants in NHANES 2003-2006, specifically the 2 NHANES cycles (2003-2004 and 2005-2006) in which serum vitamin C concentration levels were tested. (naturalmedicinejournal.com)
  • These characteristics would lead one to predict that these people would have the lowest risk of dying during the study period, but instead they were 77% more likely to die than those in Quintile 3, whose vitamin C levels were at or near the mean of the study participants. (naturalmedicinejournal.com)
  • Following overpressure exposures, participants in these studies reported elevated negative symptomology and exhibited declines in neurocognitive performance. (frontiersin.org)
  • Dietary intake of a glass of pomegranate juice (PJ) was used to assess UA producer status ( n = 100 participants) and to characterize differences in gut microbiome between UA producers from non-producers. (nature.com)
  • The study's implications are troubling," said Dr. Ana Maria Mora, a CERCH investigator and coauthor, "as the levels of the chemicals found in our study participants are within the range reported for the general U.S. population. (non-gmoreport.com)
  • Multivariable analysis controlling for a number of confounders showed that, among apparently healthy participants, insurance coverage and contact with healthcare services were not associated with higher likelihood for hypertension awareness. (cdc.gov)
  • Clinicians may consider testing urine, blood, or serum chromium levels but results may be difficult to interpret and do not guide clinical management. (cdc.gov)
  • Pooled OR was weak and non-significant for studies measuring serum pesticide level, 1.12 (0.74 to 1.50), I 2 =0.00%, p=0.966. (bmj.com)
  • Pooled OR of PC when measuring serum pesticide level was 1.12 (0.74 to 1.50), whereas a high significant association was obtained for high occupational exposure to pesticides for studies applying grouped assignment of exposure, 2.24 (1.36 to 3.11). (bmj.com)
  • Serum vitamin C level (mg/dL) was the primary exposure variable of interest. (naturalmedicinejournal.com)
  • One program, led by Jean Pfau, Idaho State University assistant professor of immunotoxicology, will compare production of blood serum antibodies among Libby residents who were exposed to asbestos only in their environment (and not at their place of employment) with antibodies seen in workers with historically long-term, heavy exposure to common commercial forms of asbestos. (isu.edu)
  • Serum cortisol and CBG levels were assayed from SSRI-exposed and non-exposed mothers and their neonates at delivery. (unboundmedicine.com)
  • Neonatal serum CBG levels were associated with infant salivary levels of evening cortisol (p ≤ 0.051). (unboundmedicine.com)
  • Prenatal SSRI exposure affects the developing HPA system by altering serum CBG levels in neonates and infant salivary cortisol levels. (unboundmedicine.com)
  • The number of welding years correlated with decreased respiratory system reactance and increased serum levels of matrix metalloproteinases 9, interleukin 6, and hepatocyte growth factor. (lu.se)
  • Serum 25(OH)D, vitamin D-binding protein (VDBP), parathyroid hormone (PTH) and calcium were measured, and 25(OH)D Bio was calculated based on VDBP levels. (medscape.com)
  • Mean chromium levels in the general U.S. population are below limits of detection (LOD) in whole blood (LOD=0.41 µg/L) and urine (LOD=0.19 µg/L), as reported in the CDC National Report on Human Exposure to Environmental Chemicals . (cdc.gov)
  • The three criteria for ranking were frequency of occurrence at NPL sites, toxicity, and potential for human exposure. (cdc.gov)
  • A definitive analysis of the impact on public health of lead-contaminated soil is limited often by a lack of information on human exposure factors and soil conditions. (cdc.gov)
  • Hotspots for human exposure to soil pollution are contaminated sites, certain agricultural and urban soils, and land that has previously been flooded. (europa.eu)
  • This happened after CDC data on human exposure to PBDEs showed 10 times higher levels in Americans compared with people in most European nations. (cdc.gov)
  • Measurement of urinary perchlorate is useful to assess recent human exposure. (cdc.gov)
  • ABSTRACT Currently no reports are available from Egypt regarding occupational exposure to nickel and its effects on the liver. (who.int)
  • Consider obtaining a urinalysis and comprehensive metabolic panel (CMP) including electrolytes, liver enzymes, and BUN/creatinine to assess for hepatic and renal injury. (cdc.gov)
  • The aim of this study was to assess the liver function of workers occupationally exposed to nickel. (who.int)
  • Damiettacityunrelatedtothenickel tionalexposuretometals[5],although assess liver function using standard platingworkshops.Thereferencegroup workersengagedinnickel-processing methods[16-18].Allthebiochemical subjects were matched for age and factoriesareexposedtonickelthrough markerswereestimatedusingarandom socioeconomicstatus(income,area inhalation,ingestionanddermalcon- accessanalyser(RA-50,Bayer). (who.int)
  • New research from the UC Berkeley School of Public Health shows that childhood exposure to the world's most widely used weed killer, glyphosate, is linked to liver inflammation and metabolic disorder in early adulthood, which could lead to liver cancer, diabetes, and cardiovascular disease later in life. (non-gmoreport.com)
  • They assessed liver and metabolic health in the children when they were 18 years old. (non-gmoreport.com)
  • The authors reported that higher levels of glyphosate residue and AMPA in urine in childhood and adolescence were associated with higher risk of liver inflammation and metabolic disorders in young adulthood. (non-gmoreport.com)
  • He teamed up with Paul J. Mills, a UC San Diego professor and author of a previous study showing an association between higher levels of glyphosate residue and AMPA in adults and non-alcoholic fatty liver disease. (non-gmoreport.com)
  • Chronic exposure to xylene can cause liver and kidney damage, with increased blood urea levels, pulmonary congestion, respiratory failure, and hepatomegaly [ 9 ]. (hindawi.com)
  • Emerging data do suggest that patients with nonalcoholic fatty liver disease (NAFLD) may be at higher risk for severe COVID-19 . (medscape.com)
  • Similarly, for patients with autoimmune hepatitis or liver transplant recipients with active COVID-19 and elevated AST/ALT levels, do not presume disease flare or acute cellular rejection without biopsy confirmation. (medscape.com)
  • The asbestos-related disease in Libby is far more aggressive and rapidly progressive than what's seen in most asbestos-exposed workers, with high rates of cancers and severe effects on respiratory function," said Dr. Levin. (isu.edu)
  • The aim of the present study was to describe the relationships between asbestos exposure and pleural plaques and asbestosis in a large cohort of formerly asbestos-exposed workers, and to assess asbestos exposure parameters linked to the presence of HRCT features of these two diseases by means of multivariate analysis. (ersjournals.com)
  • it serves as a discussion guide to begin country-specific conversations for assessing risk of exposure and categorizing levels of monitoring and movement to establish approaches commensurate with resources and policies. (cdc.gov)
  • This put workers at risk of exposure. (mesothelioma.com)
  • Cleaning up mercury pollution and reducing prenatal exposure to the neurotoxin methylmercury (MeHg) could save the European Union €10,000 million per year, finds a new study published in BioMed Central's open access journal Environmental Health . (eurekalert.org)
  • One in four low-income Canadians, for example, lives within one kilometre of a major source of industrial air pollution, resulting in higher rates of hospitalization for heart disease and respiratory illnesses. (equiterre.org)
  • Our data suggest that exposure to air pollution at the workplace in vendors could lead to allergic rhinitis. (scirp.org)
  • Babies and children sitting in bicycle trailers breathe in more polluted air than the adults riding the bikes that pull them --- but trailer covers can help halve air pollution levels, according to research from the University of Surrey. (surrey.ac.uk)
  • In research published in the Journal of Hazardous Materials Advances , Surrey's Global Centre for Clean Air Research (GCARE) found that on journeys typical of school or nursery runs, the average concentration of coarse air pollution particles in a bike trailer is 14% higher than at cyclist height and 18% higher than cyclist height in the afternoons when parents or carers typically collect children. (surrey.ac.uk)
  • It's unfortunate that the very people who help minimise pollution by cycling rather than driving can be exposing their children to higher levels of pollution, and I'd encourage adults pulling bike trailers to use covers in heavy traffic. (surrey.ac.uk)
  • In 2016 alone, exposure to outdoor air pollution led to nearly 543,000 premature deaths of children worldwide under the age of five. (surrey.ac.uk)
  • A team of researchers from across Europe used the DEMOCOPHES study of exposure to environmental chemicals to assess the impact of MeHg on humans. (eurekalert.org)
  • Researchers detected it using isocratic high-performance liquid chromatography at various laboratories. (naturalmedicinejournal.com)
  • Researchers hope to discover why Libby residents seem to have advanced rates of lung scarring, as well as the mechanism for asbestos-related scar formation and approaches to preventing scar formation after exposure has already occurred. (isu.edu)
  • The CHAMACOS researchers reached back into their "library" of frozen biological samples from mother and child dyads, along with more than 20 years of exposure data and health records. (non-gmoreport.com)
  • In their peer-reviewed study, the GCARE researchers detailed how they simulated the exposure profiles of an adult cyclist and young children sitting in a bike trailer attached to it for multiple air pollutants during the school runs in the morning and afternoon hours. (surrey.ac.uk)
  • In future, the researchers hope to secure funding to continue their research so they can build an exposure profile database in a variety of bike trailers under diverse traffic and built environmental conditions. (surrey.ac.uk)
  • Though acrylamide is known to cause adverse health effects and biomarkers exist to assess exposure to this chemical, no data on the actual acrylamide exposure in the population exist. (cdc.gov)
  • Workers exposed to fuels had higher average levels of these exposure biomarkers (HA and MHA), which were also higher in convenience store workers than in filling station attendants. (hindawi.com)
  • Another critical proposal is the reversal of the burden of proof for substances of very high concern, such as carcinogens like asbestos and benzene, and chemicals that do not break down in the environment and build up in the food chain, like musk xylene. (equiterre.org)
  • Indigenous people across Canada often have much higher body burdens of mercury, polychlorinated biphenyls, and other toxic chemicals. (equiterre.org)
  • NHANES biomonitoring data further solidified the assessment that exposure to these chemicals was high among Americans. (cdc.gov)
  • ConclUSIONS: SHS exposure, as assessed by plasma cotinine, was positively associated with hs-CRP in this group of blue-collar workers. (harvard.edu)
  • Conclusions We show for the first time that occupational exposure to pesticides is genome-wide associated with differential DNA methylation. (bmj.com)
  • We used multivariate regression analyses to assess the associations between levels of cotinine and inflammatory markers. (harvard.edu)
  • Results: The median cotinine level was 0.10 ng/mL (interquartile range, 0.04-0.23 ng/mL). (harvard.edu)
  • Plasma cotinine levels were not associated with IL-6 or sICAM-1. (harvard.edu)
  • Age mostly affected the pulmonary region and the total lung deposition with the highest deposition fraction observed for younger children. (cdc.gov)
  • Mean total deposited doses to the pulmonary region were estimated as 21, 11, and 5 mg/kg, for the high-, mid-, and low-exposure groups, respectively. (nih.gov)
  • The aim of this study was to investigate lung health in welders and evaluate new sensitive methods with potential to assess early onset pulmonary changes in occupational settings. (lu.se)
  • 232,000 of these are exposed to hazardous levels, five times higher. (eurekalert.org)
  • Chromium levels in blood or urine reflect recent exposures and are not reflective of body burden. (cdc.gov)
  • Epidemiological studies on exposure to pesticides and risk of prostate cancer (PC) provide inconsistent results. (bmj.com)
  • No association was found between low exposure to pesticides and PC, but association was significant for high exposure, pooled OR 1.33 (1.02 to 1.63), I 2 =44.8%, p=0.024. (bmj.com)
  • In spite of a weak significant association detected when pooling ORs for high occupational exposure to pesticides, the magnitude of the association was related to the method of exposure assessment used by the original studies. (bmj.com)
  • The pooled OR for PC with low exposure to pesticides was 1.02, 95% CI (0.88 to 1.17). (bmj.com)
  • The two men then approached Professor Eskenazi, who is also the founder of the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS), the longest running longitudinal birth cohort investigation on the health effects of pesticides and other environmental exposures among children in a farmworker community. (non-gmoreport.com)
  • Therefore, we assessed associations between occupational exposure to pesticides and genome-wide DNA methylation sites. (bmj.com)
  • Methods 1561 subjects of LifeLines were included with either no (n=1392), low (n=108) or high (n=61) exposure to any type of pesticides (estimated based on current or last held job). (bmj.com)
  • therefore prenatal exposure to selective serotonin reuptake inhibitor antidepressants (SSRIs) may alter HPA axis development and function. (unboundmedicine.com)
  • To address this, prenatal exposure to SSRIs and maternal mood were examined in relation to neonatal and infant levels of cortisol and its binding protein, corticosteroid-binding globulin (CBG). (unboundmedicine.com)
  • 0.0001) and cumulative exposure (p = 0.02) (or level, depending on the models used), were independently associated with the frequency of pleural plaques. (ersjournals.com)
  • A huge assumption accounting for most of the monetized benefits-that these diseases affect quality of life more like cancer, and hence monetary value is extremely high-is justified by reference to one study of cancer, not miners' diseases. (mercatus.org)
  • We have recently shown in a study that children have higher levels of PBDEs in the 4- to 6-years age range compared with adults," he said. (cdc.gov)
  • This study was designed to examine the possibility that the dose response to vitamin C might not be linear (ie, higher doses may not have the same benefits as low doses). (naturalmedicinejournal.com)
  • The study should also help determine how much asbestos exposure is necessary to cause autoimmune signs and symptoms. (isu.edu)
  • This study assessed whether this facility attracted people who inject drugs, who were socially vulnerable, and who engaged in drug-related behaviors associated with increased morbidity and mortality risk. (researchgate.net)
  • This study evaluates a wearable recording device designed to measure on-body and in-ear noise exposure, specifically in an environment with significant impulse noise resulting from firearms. (cdc.gov)
  • The aim of this study was to describe the most relevant parameters of asbestos exposure linked to pleural plaques and asbestosis diagnosed by high-resolution computed tomography (HRCT). (ersjournals.com)
  • Due to various study-dependent conditions, these studies did not provide evidence of clear relationships between asbestosis and pleural plaques and asbestos exposure. (ersjournals.com)
  • The study was initiated following a national consensus statement published in 1999 that recommended the use of chest CT scan for the surveillance of workers with previous moderate-to-high occupational exposure to asbestos 11 . (ersjournals.com)
  • The present study examined the nicotine delivery profile of third- (G3) versus second-generation (G2) e-cigarette devices and their users' exposure to nicotine and select HPHCs compared with cigarette smokers. (bmj.com)
  • Methods The study was performed in subjects with forced expiratory volume in one second at least 70% of predicted who took part in the multicentre European Community Respiratory Health Survey, had bronchial responsiveness assessed by methacholine challenge and had been genotyped for GSTM1 , GSTT1 and GSTP1 -rs1695. (bmj.com)
  • The objective of this study was to assess the exposure to toluene and xylene and to identify related signs and symptoms in gasoline station workers. (hindawi.com)
  • Methods: This study assessed the lung health and symptoms in active welders (n = 28) and controls (n = 17). (lu.se)
  • This article analyses the impact of exposure to asylum-seeking migration during the European 'refugee crisis' on votes for the far-right Alternative für Deutschland at the 2019 European elections in Berlin. (mpg.de)
  • In addition, we performed genome-wide stratified and interaction analyses by gender, smoking and airway obstruction status, and assessed associations between gene expression and methylation for genome-wide significant CpGs (n=2802). (bmj.com)
  • Although there is still no evidence for the development of cancer due to toluene, acute exposure causes immediate excitability and euphoria, followed by a depressing response with disorientation, mood fluctuations, hallucinations, and ataxia [ 8 , 9 ]. (hindawi.com)
  • The exposure must precede the outcome (eg, eliminate temporal ambiguity). (medscape.com)
  • Did exposure to asylum seeking migration affect the electoral outcome of the 'Alternative fur Deutschland' in Berlin? (mpg.de)
  • Further research is warranted on the long-term functional implications of the effect of prenatal SSRI exposure on fetal hepatic CBG gene expression and the developing HPA system. (unboundmedicine.com)
  • amobarbital will decrease the level or effect of vonoprazan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
  • efavirenz will decrease the level or effect of vonoprazan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
  • For leaded paint, the number of potentially exposed children under 7 years of age in all housing with some lead paint at potentially toxic levels is about 12 million. (cdc.gov)
  • Overall, the prevalence of both pleural plaques and asbestosis is associated with time since first exposure (TSFE) to asbestos, intensity level, duration or cumulative exposure to asbestos depending on the studies 1 - 4 , but these criteria remain poorly defined. (ersjournals.com)
  • The prevalence of allergic rhinitis was high among vendors in Dakar. (scirp.org)
  • The prevalence of nitrate exposure is likely due to nitrate intake from both food and drinking water, with foods (e.g. vegetables, milk, dairy products) thought to account for the majority of nitrate intake for typical American adults. (cdc.gov)
  • In addition, individuals exposed to the solvents present in gasoline had altered mood/depression, cramps, dizziness, drowsiness, headaches, irritability/nervousness, weakness, weight loss, and other symptoms more frequently and had higher urinary levels of HA and MHA compared to the comparison group. (hindawi.com)
  • The Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA), as well as state and local officials are investigating a link between blood lead levels (BLLs) ≥3.5 µg/dL and children consuming certain apple purée and applesauce products containing cinnamon. (cdc.gov)
  • Having measures for blood lead levels (BLLs) and a measure for age of housing together on the Tracking Network can help assess testing within areas of high risk. (cdc.gov)
  • Topics in this part include applying information about existing symptoms consistent with COVID-19, travel history of being in an outbreak area with ongoing community transmission, exposure history to suspected or confirmed cases, and diagnosis history including test results. (cdc.gov)
  • More than half of adult workers in moldy/humid buildings suffer from nasal or sinus symptoms due to mold exposure. (wikipedia.org)
  • Infants may develop respiratory symptoms as a result of exposure to Penicillium, a fungal genus. (wikipedia.org)
  • Increased exposure increases the probability of developing respiratory symptoms during the first year of life. (wikipedia.org)
  • In addition, the gestational window is critical because exposures outside certain gestational periods may be nontoxic, while the same doses can cause devastating results within the window. (medscape.com)
  • The effect of fluoride exposure during gestation and post gestation periods were studied to check the status of oxidant, antioxidant and macromolecular changes in CNS and ameliorative role of antioxidants. (fluoridealert.org)
  • The administration of antioxidants remedied the disquiet caused by high fluoride exposure at extreme vulnerable periods of life. (fluoridealert.org)
  • Bioaccumulation of POPs is typically associated with the compounds high lipid solubility and ability to accumulate in the fatty tissues of living organisms for long periods of time. (wikipedia.org)
  • Toluene is known to be neurotoxic and some of the chronic effects observed after prolonged periods of exposure include memory/concentration problems, disturbance of emotional and psychomotor functions, hepatotoxicity, nephrotoxicity, and hearing loss, which can cause permanent brain damage or even lead to death [ 9 - 11 ]. (hindawi.com)
  • Test article groups were exposed to the same concentration of aerosolized xylitol for 1, 0.5, or 0.25 h for the high, mid, and low exposures, respectively. (nih.gov)
  • Biomonitoring: Population Exposures has data on the concentration of lead in blood for the U.S. population. (cdc.gov)
  • Chronic, prolonged inhalational and skin exposure to chromium(VI) has been associated with chronic lung disease and ulceration of skin and mucous membranes. (cdc.gov)
  • People with chronic lung diseases are at higher risk for mold allergies, and will experience more severe reactions when exposed to mold. (wikipedia.org)
  • The time since first exposure (TSFE), level, duration and cumulative exposure to asbestos were used in adjusted unconditional logistic regression to model the relationships of the two diseases. (ersjournals.com)
  • Through spatial regression models, we show that exposure to asylum-seeking migration is negatively correlated with AfD vote shares, which provides support for so-called 'contact theory' and that the relationship is stronger in better-off districts. (mpg.de)
  • These lab tests are generally used to assess workers exposed to high levels in occupational settings via dermal or inhalational routes of exposure. (cdc.gov)
  • Reproductive risk of toxicant exposure includes fetal effects, especially congenital anomalies. (medscape.com)
  • Two determinations must be made when a physician responds to a patient's concerns about a specific exposure: (1) whether any quantity of the toxicant has known adverse effects on reproduction in humans and (2) whether the substance is present in sufficient quantity to affect the patient or population exposed. (medscape.com)
  • Also, the patient's level of consciousness can be briefly assessed. (medscape.com)
  • Lastly, field research assessed coworking spaces role in the socio-economic ecosystem. (ciaonet.org)
  • Finally, the effects of districts' socio-economic deprivation on the relationship between exposure to asylum-seeking migration and AfD vote shares is different in districts located in former East and West Berlin, which suggests an effect of socio-cultural history on the relationship between exposure to migration and far-right voting. (mpg.de)
  • This estimate is based on observation of elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels 1-2 times the upper limit of normal and modestly elevated total bilirubin levels early in the disease process. (medscape.com)
  • Acrylamide, a toxic and potentially cancer-causing chemical, is formed in high amounts in many types of food prepared/cooked at high temperatures. (cdc.gov)
  • Hair samples of child-mother pairs, collected from 17 European countries, demonstrated that, as a lower estimate, 1,866,000 children are born in Europe exposed to toxic levels of MeHg. (eurekalert.org)
  • Once MeHg is formed, it cycles though the environment for thousands of years, exposing humans and other species to potentially toxic levels for generations. (eurekalert.org)
  • This means that the most privileged of us can shop our way out of toxic exposure, by living in the best neighbourhoods and buying all the right things, but everyone else - especially those socially or economically marginalized communities - are left to bear the toxic burdens . (equiterre.org)
  • Exposure to toxic levels of cyanide can result from numerous chemical reactions. (cdc.gov)
  • There is evidence that even relatively low-level exposures to Libby asbestos can cause serious scarring lung diseases, which markedly impair respiratory function, as well as asbestos-related cancers like lung cancer and mesothelioma, which occur at higher rates among the Libby population than elsewhere in the United States. (isu.edu)
  • Asbestos exposure can lead to the development of benign and malignant respiratory diseases. (ersjournals.com)
  • However, the health assessor will find the information in this report useful in characterizing the significance of exposure pathways and the importance of the physical and chemical properties of the lead compounds that may impact on persons' uptake of lead. (cdc.gov)
  • On 21st postnatal day pups were sacrificed and biochemical parameters were assessed. (fluoridealert.org)
  • Because acrylamide is formed during the cooking process, specifically when producing French fries, potato chips and other fried products, intake of acrylamide through consumption of these foods can be high, thus exposing a large portion of the population to this chemical and putting them at risk of adverse health effects. (cdc.gov)
  • Blood samples, subjective effects, device characteristics and e-liquid consumption were assessed. (bmj.com)
  • ObjectiveS: We assessed the association between SHS exposure and the inflammatory markers high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and soluble inter-cellular adhesion molecule-1 (sICAM-1) in 199 non-smoking U. S. trucking industry workers. (harvard.edu)
  • Airspace dimension assessment indices were correlated with increasing levels of inflammatory markers and matrix metalloproteinases. (lu.se)
  • Most of these deaths occur in vulnerable groups, such as children and the elderly, affected by long-term exposure. (europa.eu)
  • 3 We mapped flood-risk data from the U.K.'s Environment Agency (EA) to 11,000-plus private real estate assets 4 in England within MSCI's database of measured client portfolios 5 to assess which ones were most vulnerable to flooding. (msci.com)
  • 16 The SIFs are designed to attract high-risk, socially vulnerable PWID. (researchgate.net)
  • Its inhibitory effect on thyroid hormone production has led to concerns that exposure even to low levels of perchlorate in the environment might affect vulnerable groups, such as pregnant women with inadequate iodine intake and infants for whom thyroid hormone levels must be maintained adequately for normal brain development. (cdc.gov)
  • His PhD thesis was to research occupational and dietary exposure to certain pollutants, with special emphasis on polybrominated diphenyl ethers (PBDEs), a type of flame retardant. (cdc.gov)
  • The commonest asbestos-related diseases are benign diseases and many studies have examined the relationships between asbestos exposure and these diseases 1 . (ersjournals.com)
  • Dermal contact is considered a relatively unimportant type of exposure since little of the depleted uranium will pass across the skin into the blood. (who.int)
  • The new Aerosol Transmittable Disease (ATD) Standard was designed to protect workers from just this type of exposure," said DIR director John C. Duncan. (infectioncontroltoday.com)
  • The impact of the methodology applied for assessment of exposure on the pooled OR was evident. (bmj.com)
  • In France, the computerized system for flight assessment of exposure to cosmic radiation in air transport (SIEVERT) is delivered to airlines for assisting them in the application of the European directive. (radioprotection.org)
  • Because the baseline risk is small, if an exposure conveys a modestly increased risk, a large population of infants is required to detect an increase in anomalies. (medscape.com)
  • Only 12% of subjects had detectable levels of UA at baseline. (nature.com)
  • Traditionally, supply chains were designed primarily to meet two overarching objectives: cost efficiency and optimal service levels. (bcg.com)
  • Accumulating evidence suggests that blast exposures can result in negative effects on the brain in absence of a medically diagnosable injury ( 2 - 5 ). (frontiersin.org)
  • The No Observed Effect Level was the high-exposure level and suggests that inhaled xylitol is safe for clinical administration. (nih.gov)
  • Diet questionnaires and fecal samples were collected to compare differences between UA producers and non-producers along with plasma samples at different time points to assess levels of UA and its conjugates between the interventions. (nature.com)
  • For many chemical plant workers, asbestos exposure may have happened at work. (mesothelioma.com)
  • Workers continue to face exposure today from old asbestos products. (mesothelioma.com)
  • This put plant workers at high risk of inhaling or ingesting asbestos fibers. (mesothelioma.com)
  • As a result, chemical plant workers continue to be at risk of asbestos exposure. (mesothelioma.com)
  • Chemical plant workers at these companies may have experienced asbestos exposure. (mesothelioma.com)
  • Gasoline station workers showed high levels of HA and MHA, reflecting high occupational exposure to the solvents toluene and xylene present in gasoline, demonstrating that changes in the current legislation and in the work environment are necessary to ensure better health protection for these workers. (hindawi.com)
  • Laboratory testing for blood lead levels is available through most clinical laboratories. (cdc.gov)
  • Refer to CDC's guidance on testing children for lead exposure and the American Academy of Pediatrics' clinical guidance for managing lead exposure in children . (cdc.gov)
  • Medical treatment for chromium exposure is supportive as indicated from the clinical presentation. (cdc.gov)
  • [ 2 ] A number of modalities may be required for diagnosis and treatment of exposures in pregnancy. (medscape.com)
  • However, the majority of published studies are based on CXR data, resulting in difficulties for estimation of dose-response relationships for asbestos-related diseases due to imprecise assessment of asbestos exposure but also imprecise radiographic diagnosis of asbestosis and pleural plaques 3 . (ersjournals.com)
  • Thoracic high-resolution computed tomography (HRCT) has been clearly demonstrated to be more sensitive and specific than CXR for the diagnosis of asbestos-related diseases 5 . (ersjournals.com)
  • However, little is known how aldehyde exposure from e-cigarettes, when coupled with an inactivating ALDH2 genetic variant, ALDH2*2 (present in 8% of the world population), affects cardiovascular oxidative stress. (bvsalud.org)
  • The primary exposures include diagnostic radiographs, radiopharmaceuticals, workplace exposures, and environmental exposures such as those that occurred after the Three Mile Island and Chernobyl nuclear reactor accidents. (medscape.com)
  • The recommendations are based on individual-level risk assessment of potential infection of arriving travelers to mitigate the geographic spread of coronavirus disease 2019 (COVID-19). (cdc.gov)
  • The research project will also examine the relationships between autoimmune disorders, auto-immune antibody abnormalities, and CT scan evidence of scarring lung disease in the context of exposure to Libby asbestos. (isu.edu)
  • In 2001, Bégin and Christman 10 highlighted the need for an objective and independent measurement of disease activity, such as HRCT, but emphasised that computed tomography (CT) scanning was not yet a "gold standard", despite its higher sensitivity compared with CXR, due to the absence of clearly established exposure-response relationships. (ersjournals.com)
  • [ 6-9 ] For instance, low 25(OH)D was associated with a high risk of coronary heart disease or reduced bone mineral density in whites, but not in blacks. (medscape.com)