High hydrostatic pressure inhibits. Medical search. Frequent questions

The bulk of heterotrophic activity under in situ pressure is always lower than under atmospheric pressure conditions and is increasingly inhibited with increasing hydrostatic pressure. (us-ocb.org)
Based on microbial activity measurements in the major oceanic basins using an in situ microbial incubator, we show that the bulk heterotrophic activity of prokaryotic communities becomes increasingly inhibited at higher hydrostatic pressure. (microbial-oceanography.eu)

At 4,000 m depth, the bulk heterotrophic prokaryotic activity under in situ hydrostatic pressure was about one-third of that measured in the same community at atmospheric pressure conditions. (microbial-oceanography.eu)

Because hydrostatic pressure can be a major factor in chondroinduction of mesenchymal stem cells, it was proposed to investigate the importance of the cytoskeleton in transduction of hydrostatic pressure by C3H10T1/2 murine fibroblasts, a model of primary bone marrow mesenchymal stem cells. (openorthopaedicsjournal.com)

Single-cell analysis revealed that deep sea prokaryotic communities consist of a small fraction of pressure-loving (piezophilic) microbes while the vast majority is pressure-insensitive (piezotolerant). (us-ocb.org)

In addition, FN has been shown to inhibit apoptosis via various intracellular pathways 20 . (nature.com)
Likewise, dexamethasone can reduce cerebral cell apoptosis and inhibit inflammation [ 10 ,] and deferoxamine (DFX) provides new therapy target [ 11 ]. (karger.com)

Spironolactone inhibits the aldosterone receptor in the cortical collecting duct, also limiting sodium and water reabsorption. (medscape.com)
Inhibition of renin secretion inhibit RAAS inhibit aldosterone production Blood volume (towards normal) (b) ADH secretion blood volume (towards normal). (slidetodoc.com)

Spaceflight associated Neuro-Ocular Syndrome (SANS)-formerly called visual impairment and intracranial pressure (VIIP) syndrome [1] -is a constellation of findings and symptoms that have been found in astronauts who have undergone long duration space flight (LDSF) missions in microgravity environments (e.g. (aao.org)
[2] SANS enterprises a constellation of signs that are only partially and problematically elucidated solely by increased intracranial pressure (ICP). (aao.org)
Known to be a multifaceted mechanism consisting of components of the theory of cephalad fluid shift, compartmentalization & alternative compartmentalization theories, increased intracranial pressure, differential translaminar pressure gradients, aberrancies in lymphatic drainage systems, intracerebral volume shifts, orbital and cerebral arterial and vortex vein drainage alterations, cyanocobalamin- & folate-dependent one-carbon pathway variances, choroidal volume expansion, and ambient hypercapnic environments onboard the ISS may contribute to the SANS constellation. (aao.org)
These cephalad fluid shifts may cause increased hydrostatic pressure in the brain (intracranial pressure) [2] and orbit (optic nerve sheath). (aao.org)

C3H10T1/2 cells were cultured as pellets in either 4µM cytochalasin D or 4µM nocodazole and subjected to 3 days of cyclic hydrostatic compression (1 Hz, 5 MPa, 2 h per day). (openorthopaedicsjournal.com)
Thus upregulation of macromolecular gene expression by cyclic hydrostatic pressure did not require a completely intact cytoskeleton. (openorthopaedicsjournal.com)
In primary bovine chondrocytes subjected to 5 MPa of cyclic hydrostatic pressure the actin stress fibers resembled those of non-pressurized controls. (openorthopaedicsjournal.com)
1.1 This practice establishes two procedures, Procedure A (cyclic) and Procedure B (static), for obtaining a hydrostatic design basis (HDB) or a pressure design basis (PDB) for fiberglass piping products, by evaluating strength-regression data derived from testing pipe or fittings, or both, of the same materials and construction, either separately or in assemblies. (astm.org)

Effect of Hydrostatic Pressure on the Deformation Behavior of Polyethylene and Polycarbonate in Tension and in Compression. (dtic.mil)
The stress-strain response of crystalline high density polyethylene and of amorphous polycarbonate has been determined in tension and in compression at superimposed pressures up to 1104 MPa 160 ksi. (dtic.mil)
Hydrostatic compression under high pressure inhibits separation processes binders in FRP, and as a result increase of their strength characteristics. (depotmind.ru)

But in comparison to continuous sterilisers the steam and water consumption are higher. (idoc.pub)
Batch Sterilizers Continuous pressure steriliser There are three types of continuous sterilisers: 1. (idoc.pub)
The Continuous pressure cooker-cooler. (idoc.pub)
The Continuous pressure cooker-cooler sterilisers are of non-agitating types. (idoc.pub)
Continuous Rotary sterilisers (Inside View) In the Hydrostatic sterilisers, hot water columns are used to generate pressure. (idoc.pub)

Model diatom-bacteria aggregates, cultures of the aggregate-forming diatom Skeletonema marinoi, and seawater microbial communities devoid of diatoms showed incomplete and complete inhibition of respiration activity when exposed to pressure levels of 10-50 and 60-100 MPa, respectively. (sdu.dk)

Acute elevation of left ventricular preload (end-diastolic pressure) directly leads to elevated left atrial pressures and pulmonary edema. (medscape.com)
An increased blood volume stretch of atria activate atrial volume receptors sensory afferent nerves to medulla inhibiting the cardiovascular centre This results into decreased blood volume through: (a) sympathetic drive to kidney: - dilate afferent arterioles glomerular capillary hydrostatic pressure GFR blood volume (towards normal). (slidetodoc.com)

Real time RT-PCR revealed that both drugs substantially lowered the basal level of aggrecan and col2a1 mRNA, but that neither drug prevented a pressure-stimulated increase in gene expression relative to the altered basal state. (openorthopaedicsjournal.com)

Effect of High Hydrostatic Pressure Treatment on Physiological Characteristics of Rice Plants (Oryza sativa L. (gywlxb.cn)

Red bean extract inhibits lipopolysaccharide-induced inflammation and H2O2-induced oxidative stress in Raw 264.7 macrophages. (notulaebotanicae.ro)

Glucocorticoids bind steroid receptors in the cytoplasm, alter DNA expression and inhibit formation of inflammatory mediators such as interleukin-6 (IL-6), IL-8, prostaglandins, and vascular endothelial growth factor (VEGF). (dovepress.com)
Diuretics reduce intravascular volume, leading to a decrease in central venous pressure, right and left heart filling pressures, and pulmonary vascular pressures. (medscape.com)
We and others have identified functional MR in human vascular smooth muscle cells (SMCs), suggesting that vascular MR might directly regulate blood pressure. (onteenstoday.com)
17β-Estradiol is a more potent vasorelaxant in high K+-depolarized vascular preparations than in those contracted with various receptor agonists. (onteenstoday.com)

First, cephalad fluid shifts may lead to increased intracranial volume and/or pressure. (aao.org)
Hydrostatic pressure elevation leads to fluid extravasation into peripheral tissues as well as the lungs. (medscape.com)
Blood flow through the body is regulated by the size of blood vessels, by the action of smooth muscle, by one-way valves, and by the fluid pressure of the blood itself. (onteenstoday.com)

Dongkui bayberry fruit extract (BFE) prepared using the ultrasonic method exhibited a significantly higher value for the total phenolic content (TPC) and had lower 50% inhibitory concentration (IC 50 ) values of scavenging activities against 1,1-diphenyl-2- picrylhydrazyl (DPPH), 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid (ABTS), and hydrogen peroxide (H 2 O 2 ), as well as reducing power compared to the other treatment. (notulaebotanicae.ro)
Furthermore, compared to the Nakai BFE, macrophages exposed to the Dongkui BFE by the ultrasonic extraction method significantly inhibited LPS-induced production of tumor necrosis factor-α at a concentration of the extract of 0.25 mg/mL. (notulaebotanicae.ro)
Some deep-sea pelagic groups, such as the lanternfish, ridgehead, marine hatchetfish, and lightfish families are sometimes termed pseudoceanic because, rather than having an even distribution in open water, they occur in significantly higher abundances around structural oases, notably seamounts and over continental slopes. (encyclopedia.pub)
RESULTS: The prevalence of a doctor visit in the past 12 months was significantly higher among adults with IBD than those without. (cdc.gov)

The deep sea is also an extremely hostile environment, with temperatures that rarely exceed 3 °C (37.4 °F) and fall as low as −1.8 °C (28.76 °F) (with the exception of hydrothermal vent ecosystems that can exceed 350 °C, or 662 °F), low oxygen levels, and pressures between 20 and 1,000 atmospheres (between 2 and 100 megapascals). (encyclopedia.pub)
1-4 Pressure is applied at 2 to 3 atmospheres absolute, which is the sum of the atmospheric pressure (1 atm) plus an additional hydrostatic pressure equivalent to one or two atmospheres. (woundeducators.com)

The inactivation of EF-2 by toxins inhibits protein production in the host, causing symptoms due to loss of function in affected cells. (wikipedia.org)
Interestingly, RNA-seq revealed that G. haimaensis hosts responded to B. pettiboneaei parasitism through significant upregulation of protein and lipid anabolism related genes, and that this parasitism may enhance host mussel nutrient anabolism but inhibit the host's ability to absorb nutrients, thus potentially helping the parasite obtain nutrients from the host. (frontiersin.org)
The pyridine derivative Y 27632 is known to inhibit the Rho linked protein kinase pathway, which in turn directly decreases actomyosin mediated contractile tension. (pi3k-inhibitors.com)
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. (cancer-genetics.org)

Hyperbaric oxygen therapy (HBOT) refers to an adjunctive treatment modality in which a patient inhales 100% oxygen under an elevated pressure for a pre-specified period of time. (woundeducators.com)
The condition in which tissue oxygen levels are reduced to below around 30 mmHg is known as ischemia or tissue hypoxia, and this state fundamentally impairs the normal cellular processes and inhibits wound healing. (woundeducators.com)
Finally, a lack of oxygen reduces the resistance of tissues to infection, while high oxygen concentration enhances the ability of leukocytes to produce free radicals, causing bacterial death. (woundeducators.com)

However, high dilutions with water can result in a disruption of the supramolecular structure of NADES as water molecules will compete with NADES components for hydrogen bonding. (frontiersin.org)

The rate of aging decreased with osmotic pressure, supporting the idea that water is important for stabilizing the transition state. (inra.fr)

Deep sea microbial communities are experiencing increasing hydrostatic pressure with depth. (us-ocb.org)
It is known that some deep sea microbes require high hydrostatic pressure for growth, but most measurements of deep-sea microbial activity have been performed under atmospheric pressure conditions. (us-ocb.org)
They compared microbial activity in situ with activity under atmospheric pressure at 27 stations from 175 to 4000 m depths in the Atlantic, Pacific, and the Southern Ocean. (us-ocb.org)
Figure caption: Deep sea microbial activity under varying pressure. (us-ocb.org)
Deep-sea microbial communities are exposed to high-pressure conditions, which has a variable impact on prokaryotes depending on whether they are piezophilic (that is, pressure-loving), piezotolerant or piezosensitive. (microbial-oceanography.eu)
While it has been suggested that elevated pressures lead to higher community-level metabolic rates, the response of these deep-sea microbial communities to the high-pressure conditions of the deep sea is poorly understood. (microbial-oceanography.eu)

Yizhou has advanced SMMSS production line, Fabrics with high hydrostatic resistance and good air permeability can be produced. (yznonwoven.com)
After the triple antibody treatment, the fabric has good alcohol resistance, Anti - blood pressure, anti - oil effect, and does not affect its hydrostatic resistance and permeability performance. (yznonwoven.com)

1. THE BARORECEPTORS q At normal arterial pressure the baroreceptors are active. (slidetodoc.com)

a) In situ bulk leucine incorporation rates normalized to rates obtained at atmospheric pressure conditions. (us-ocb.org)
b) A microscopic view of a 2000 m sample collected in the Atlantic and incubated under atmospheric pressure conditions. (us-ocb.org)

According to WHOI geophysicist Rob Reves-Sohn, chief scientist of the expedition, as quoted in the 14 August 2008 issue of Oceanus , "These are the first pyroclastic deposits we've ever found in such deep water, at oppressive pressures that inhibit the formation of steam, and many people thought this was not possible. (si.edu)

It has dual-phase pharmacokinetics, initially releasing high dose of dexamethasone peaking at day 60, followed by rapid decline in concentration between day 60 and 90 followed by a steady state at a much lower concentration that is maintained through day 180 in primate eyes. (dovepress.com)

Thus, the in crease in curvature not simply increases the velocity at positions of higher community curvature, but also leads to a general velocity improve throughout the full collective even at positions with out increased curvature. (pi3k-inhibitors.com)
The Frank-Starling law describes the mechanism whereby a normal heart under a physiologic range of filling pressures increases stroke volume proportionally with an increase in preload. (medscape.com)
q Increased blood pressure increases their rate of activity, while decreased pressure decreases the rate of firing (activity). (slidetodoc.com)
Intracerebral hemorrhage (ICH) accounts for about 10-15% of all strokes with high mortality [ 1 ], 1-month mortality of ICH is approximate 40% and it increases with age [ 2 ]. (karger.com)

First, porcelain tiles have high mechanical strength and are extremely chip resistant. (villagiotile.com)
Polyprufe ® BSW15 is highly resistant to hydrostatic pressure, ground settlement, and soil chemicals. (elmich.com)

Extraction of anthocyanins from grape by-products assisted by ultrasonics, high hydrostatic pressure or pulsed electric fields: A comparison. (notulaebotanicae.ro)

Safety concerns include cataract formation and progression, intraocular pressure elevation, complications related to intravitreal injection, and opportunistic infections secondary to steroid-induced immune suppression. (dovepress.com)
On top of that, it has been shown that extracellular compressive worry such as a single imposed from the hydrostatic pressure plays a purpose in leader cell formation. (pi3k-inhibitors.com)
On the other hand, the non-enzymatic antioxidants block and cut the damaging chain reaction caused by ROS or even inhibit the formation of free radicals. (meliponinibeehoney.com)
Formation pressure is controlled through mud density. (cupdf.com)
Hydrostatic pressure from the mud should normally match or exceed the formation pressure, preventing a cave-in. (cupdf.com)
If mud exceed the formation pressure, preventing a cave-in. (cupdf.com)

This method does not fully follow the industrial hockey sticks production technology also by using high quality reinforced materials (carbon fiber, fiberglass, epoxy resin). (depotmind.ru)
Bacteria process half of the ocean's primary production, remineralize dissolved organic matter, and re-direct otherwise lost organic matter to higher trophic levels. (us-ocb.org)
b) Bacterial iron consumption in the upper 120m of the ocean and (c) Changes (anomalies) in export carbon production when bacteria have a high requirement for iron. (us-ocb.org)

Note 2-This limitation, based on thin-wall pipe design theory, serves further to limit the application of this practice to internal pressures which, by the hoop-stress equation, are approximately 20 % of the derived hydrostatic design stress (HDS). (astm.org)
What is the correct equation for measuring blood pressure? (easynotecards.com)

Using a novel high-pressure setup, we tested the hypothesis that increasing levels of hydrostatic pressure inhibit POC degradation in aggregates rapidly sinking to the ocean interior. (sdu.dk)
If your metabolism is "high" (or fast), meaning that you'll need to take in more calories as your body naturally uses energy more rapidly than someone with a "low" (or slow) metabolism. (optixanthin.com)

The effect of hydrostatic and osmotic pressures on the aging process of DFP-phosphorylated enzymes (diisopropylphosphoryl-BuChE (DIP-BuChE)) was investigated. (inra.fr)
On the other hand, pressure had little effect on the aging of the DIP-E197D mutant and no effect on the DIP-D70G mutant, indicating that the transition state of the aging reaction (dealkylation of an isoproxy chain) was associated with an extended conformation/hydration change in wtBuChE but not in mutants. (inra.fr)

However, the mechanism(s) of hydrostatic pressure mechanotransduction is not well understood. (openorthopaedicsjournal.com)

1.3 This practice provides a PDB for complex-shaped products or systems where complex stress fields seriously inhibit the use of hoop stress. (astm.org)
1.4.2 Free Ends -Specimens are stressed by internal pressure in both hoop and longitudinal directions, such that the hoop stress is twice as large as the longitudinal stress. (astm.org)

Wild-type (wt) butyrylcholinesterase (BuChE) and the E197D and D70G mutants were inhibited by diisopropylfluorophosphate (DFP) or soman under standard conditions of pH, temperature and pressure. (inra.fr)

Respiration activity, a proxy for POC degradation, was measured directly and continuously at up to 100 MPa (corresponding to 10 km water depth) in a rotating pressure tank that keeps the aggregates in a sinking mode. (sdu.dk)
The high viscosity of NADES can hinder their extractive efficiency, which can be reduced by adding a certain percentage of water or by working at higher temperatures. (frontiersin.org)
By effectively inhibiting sodium reabsorption, they also reduce water reabsorption. (medscape.com)
They inhibit the Na-Cl symporter in the distal convoluted tubule, leading to decreased sodium and water reabsorption. (medscape.com)
Sodium and free water retention occur, resulting in an increase in both volume and pressure in capacitance vessels. (medscape.com)
Water crosses cell membranes freely from areas of low solute concentration to areas of high solute concentration. (msdmanuals.com)

Pressure contributes to obtain a uniform thickness, as well as the partial displacement of air bubbles and other volatile products. (depotmind.ru)

In contrast, in acute decompensated heart failure, a myopathic heart subjected to very elevated filling pressures is not able to effectively increase stroke volume. (medscape.com)

The results suggested that high hydrostatic pressure treatment is possible served as a new method of breeding in the future. (gywlxb.cn)
It can be postulated that the antioxidant effects of stingless bee honey can also be applied to the treatment of wounds since its antioxidant content is higher or similar to that of other types of honey. (meliponinibeehoney.com)
High-pressure treatment of cloudy apple juice. (potravinarstvo.com)

These receptors provide information to the cardiovascular centres in the medulla oblongata about the degree of stretch with pressure changes. (slidetodoc.com)

1. THE BARORECEPTORS Changes in MAP are detected by baroreceptors (pressure receptors) in the carotid and aortic arteries. (slidetodoc.com)
Does smooth muscle controls blood flow through arteries and veins and controls blood pressure? (onteenstoday.com)
Blood pressure is related to the blood velocity in the arteries and arterioles. (onteenstoday.com)
How does the smooth muscle in the wall of muscular arteries help to maintain blood pressure? (onteenstoday.com)

Through a series of computer simulations performed in the global ocean ecosystem model, the authors found that iron is a limiting factor for bacterial growth in iron-limited regions in the Southern Ocean, the tropical, and the subarctic Pacific due to the high iron requirement and iron uptake capability of bacteria. (us-ocb.org)
Plant growth was inhibited in both treated cultivars during the early growth stage of seedling, but could exceed that of the contrast after sowing of 35 d. (gywlxb.cn)
The total average photosynthetic pigment content was higher in both treated cultivars than their untreated during different growth stage. (gywlxb.cn)

Despite piezosensitive-like prokaryotes comprising only ~10% (mainly members of Bacteroidetes, Alteromonas) of the deep-sea prokaryotic community, the more than 100-fold metabolic activity increase of these piezosensitive prokaryotes upon depressurization leads to high apparent bulk metabolic activity. (microbial-oceanography.eu)

These curvatures correspond to alternating phases of high and low respiration activity likely connected to pressure effects on unidentified metabolic processes in S. marinoi. (sdu.dk)

There is, however, increasing evidence that fresh aggregates can reach great depth and sustain relatively high biological activity in the deep sea. (sdu.dk)

Associated risk factors predisposing to increased ICP during LDSF, and consequently SANS, include high salt diets, intensive resistive exercise, liability to inflated ambient CO2 concentrations, lack of good nutrition [8] , and biochemical aberrancies in cyanocobalamin- & folate-dependent 1-carbon transfer pathways. (aao.org)

LECTURE OBJECTIVES § Factors regulating arterial blood pressure § Explain how they influence arterial blood pressure. (slidetodoc.com)
nervous, hormonal and renal regulation of arterial blood pressure. (slidetodoc.com)
How does smooth muscle affect blood pressure? (onteenstoday.com)
Excessive vasoconstriction leads to high blood pressure, while excessive vasodilation as in shock leads to low blood pressure. (onteenstoday.com)
What are the two main ways your body controls blood pressure? (onteenstoday.com)
Currently, treatments for ICH are focusing on the primary injury including reducing intracranial hypertension, blood pressure control, and rehabilitation. (karger.com)

Electrophoresis under high pressure up to 2.5 kbar showed that aged wtBuChE did not undergo pressure-induced molten globule transition unlike the native enzyme. (inra.fr)

2. THE CHEMORECEPTOR REFLEX q Chemoreceptors have high blood flow (1200 ml/min/g tissue). (slidetodoc.com)

Li R, Nortamo P, Valmu L , Tolvanen M, Huuskonen J, Kantor C and Gahmberg C G (1993) A peptide from ICAM-2 binds to the Leu-kocyte Integrin CD11a/CD18 and inhibits endot-helial cell adhesion. (leenavalmu.fi)
Bleb bistatin inhibits myosin II action and so cell motil ity. (pi3k-inhibitors.com)
Beyond this protective role, Mrr can inflict chromosomal DNA damage that elicits the SOS response in the host cell upon heterologous expression of specific methyltransferases such as M.HhaII, or after exposure to high pressure (HP). (uci.edu)

High-pressure injection atomizes fuel into finer particles which burn more completely. (martintractorinc.com)

Additionally, the antioxidant properties of malts were higher than those obtained for barleys. (lidsen.com)
Furthermore, given the high content of soluble solids (mainly carbohydrates, antioxidant compounds such as free phenolic acids and free amino acids, and GABA), malted flours would be novel ingredients for preparing beverages with bio-functional properties. (lidsen.com)

High-dose B vitamin supplementation acid, vitamins B6, B12, D and calcium improves folate and folate levels uncovered making use of deeply and cognitive decline in Alzheimer disease: status and decreases plasma homocysteine sequenced large datasets [url=https://modestedu.com/technology/order-online-pirfenex-no-rx/] medications neuropathy purchase generic pirfenex online[/url]. (ehd.org)

Intracerebral hemorrhage (ICH) is a subtype of stroke with a severe high mortality and disability rate and accounts for about 10-15% of all strokes. (karger.com)

Batch Sterilizers: In batch and non-agitating type of sterilisers the labour requirement is high but still they are quite popular. (idoc.pub)

2. Extra pressure from the swelling may cause caving and/or mechanical sticking of the drill string. (cupdf.com)

A British trial showed that HBOT resulted in a signiﬁcantly higher percentage of healthy graft area in split skin grafts (RR 3.50, 95% CI 1.35-9.11), while a Chinese trial showed that HBOT did not signiﬁcantly improve ﬂap survival in patients with limb skin defects. (woundeducators.com)

Organisms3

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Phenomena and Processes11

Technology, Industry, Agriculture3

Health Care4

Increasingly inhibited2

Activity under in situ1

Mesenchymal stem1

Prokaryotic communities1

Apoptosis2

Aldosterone2

Intracranial pressure4

Cyclic4

Compression3

Continuous5

Inhibition1

Atrial2

Substantially1

Physiological1

Inflammation1

Vascular4

Fluid3

Significantly4

Atmospheres2

Protein4

Oxygen3

Disruption1

Osmotic pressure1

Microbial6

Resistance2

Arterial pressure1

Atmospheric pressure conditions2

Steam1

Dexamethasone1

Increases4

Resistant2

Extraction1

Formation6

Production3

Equation2

Rapidly2

Effect2

Understood1

Stress2

Temperature1

Water6

Products1

Acute1

Treatment3

Stretch1

Arteries4

Growth3

Piezosensitive1

Metabolic1

Depth1

Carbon1

Blood pressure6

Undergo1

Tissue1

Cell3

Injection1

Antioxidant2

Dose1

Stroke1

Type1

Mechanical1

Percentage1