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  • receptors
  • Heterotrimeric guanine-nucleotide binding proteins (G-proteins) are best known for transducing a wide array of extracellular signals received from heptahelical (7TM) cell-surface receptors, such as those initiated by hormones in the bloodstream, neurotransmitters across the synapse, and photons striking the retina. (ijbs.com)
  • role
  • To examine a role for the heterotrimeric KIF3A-KIF3B-KAP3 kinesin-2 motor complex in regulating GLI activity, we performed a series of structure-function analyses using biochemical, cell signaling and in vivo approaches that define novel specific interactions between GLI proteins and two components of this complex, KAP3 and KIF3A. (nih.gov)
  • BACKGROUND: Gq is a heterotrimeric G protein that plays an important role in numerous physiological processes. (uva.nl)
  • form
  • Principles that guide folding of coiled coils were tested by designing three peptides that preferentially associate with each other to form a heterotrimeric coiled coil. (nih.gov)
  • family
  • Here, we show that WNT-5A evokes a proliferative response in a mouse microglia-like cell line (N13), which is sensitive to pertussis toxin, thus implicating the involvement of heterotrimeric G proteins of the G(i/o) family. (muni.cz)
  • plant
  • This study shows that heterotrimeric G proteins modulate stem cell proliferation in the plant shoot apical meristem via CLAVATA signaling pathway and provides evidence that that CLV3 peptide receptor RPK2 is a novel G protein‐coupled receptor. (embopress.org)