• The sequences obtained from the isolated spots revealed that they have close similarity to creatine kinase B (CKB) isoforms, heterogeneous nuclear ribonucleoprotein F (hnRNP F) and high mobility group box 1 protein (HMGB1) isoforms. (nih.gov)
  • Although this gene is named HNRNPAB in reference to its first cloning as an RNA binding protein with similarity to HNRNP A and HNRNP B, it is not a member of the HNRNP A/B subfamily of HNRNPs, but groups together closely with HNRNPD/AUF1 and HNRNPDL. (wikipedia.org)
  • Further studies done in arthritis mouse models established that this antibody is against a spliceosome, which is a heterogeneous ribonucleoprotein complex (36 KDa) A2 protein (hnRNP A2). (medscape.com)
  • 8. The Drosophila Hrb87F gene encodes a new member of the A and B hnRNP protein group. (nih.gov)
  • 10. Evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) A/B proteins functionally interact with human and Drosophila TAR DNA-binding protein 43 (TDP-43). (nih.gov)
  • 13. The role of the heterogeneous nuclear ribonucleoprotein (hnRNP) Hrb27C in regulating lipid storage in the Drosophila fat body. (nih.gov)
  • Altered expression and localization of creatine kinase B, heterogeneous nuclear ribonucleoprotein F, and high mobility group box 1 protein in the nuclear matrix associated with colon cancer. (nih.gov)
  • Heterogeneous nuclear ribonucleoprotein A/B, also known as HNRNPAB, is a protein which in humans is encoded by the HNRNPAB gene. (wikipedia.org)
  • Anti-RA33 antibody was discovered by Hassfeld et al in 1989 and was found to bind a specific nuclear protein in HeLa cells. (medscape.com)
  • 12. A protein of the SR family of splicing factors binds extensively to exonic Balbiani ring pre-mRNA and accompanies the RNA from the gene to the nuclear pore. (nih.gov)
  • This function is carried out by the splicing machinery which comprises RNA-protein complexes called little nuclear ribonucleoprotein contaminants (snRNP). (biosemiotics2013.org)
  • The expression of Ang2 and Tie2 mRNA in HUVECs, the secretory volume of Ang2 in supernatant of cell culture and the expression of Tie2 protein in HUVECs were detected by RealTime PCR, ELISA and Western blotting respectively in each group. (shsmu.edu.cn)
  • A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1. (colorado.edu)
  • 7. Heterogeneous nuclear ribonucleoprotein complexes and proteins in Drosophila melanogaster. (nih.gov)
  • 3′UTRs form ribonucleoprotein (RNP) with many RNA binding proteins (RBPs). (molcells.org)
  • Additionally, we have identified a novel association between Plk1 and p53 through heterogeneous ribonucleoprotein C1/C2 (hnRNPC), thus providing valuable insight into Plk1's role in cancer cell survival. (nih.gov)
  • The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. (wikipedia.org)
  • 8. Bonnet A and Palancade B. Regulation of mRNA trafficking by nuclear pore complexes. (prolekarniky.cz)
  • Aiding and abetting cancer: mRNA export and the nuclear pore. (prolekarniky.cz)
  • 2. Exon skipping by overexpression of a Drosophila heterogeneous nuclear ribonucleoprotein in vivo. (nih.gov)
  • One of these genes is heterogenous nuclear ribonucleoprotein U ( HNRNPU ). (ki.se)
  • 5. Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF. (nih.gov)
  • 20. Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA. (nih.gov)
  • We expand the genetic characterization of nuclear export factor NXF-1 to other members of the mRNA export pathway to model mRNA export and recycling of NXF-1 back to the nucleus. (prolekarniky.cz)
  • Surprisingly, subcellular levels of CKB were decreased in colon tumors, suggesting that the observed high CKB levels in nuclear matrix extracts are caused by the enhanced localization of CKB to the nuclear matrix during colon tumorigenesis. (nih.gov)
  • 9] Other groups mentioned that the frequency of positive RF, AKA and anti-CCP were lower in early RA but a similar trend was not noticed for the anti-RA33 antibody. (medscape.com)
  • Together with antibodies specific for nuclear constituents, immunoreactivities to cytoplasmic components are also identified. (bmj.com)
  • A previous study from our laboratory showed specific alterations of nuclear structure in colon cancer. (nih.gov)
  • This study examined whether high-mobility group box 1 (HMGB1), a damage-associated molecular pattern (DAMP) molecule, is involved in the infiltration of T cells and disease progression in locally advanced colon cancer. (biomedcentral.com)
  • More importantly, the expression of HMGB1 was observed in both the nucleus and the cytoplasm (co-expression pattern) in a subset of colon cancer tissues, whereas nuclear-only expression of HMGB1 (nuclear expression pattern) existed in most of the cancer tissues and normal mucosa. (biomedcentral.com)
  • Nucleophosmin (NPM), also known as B23, 1 NO38, and numatrin, is an abundant, highly conserved, ubiquitously expressed nucleolar phosphoprotein which belongs to the nucleoplasmin/nucleophosmin family of nuclear chaperones. (haematologica.org)
  • The nuclear transport machinery in Caenorhabditis elegans: A central role in morphogenesis. (prolekarniky.cz)
  • Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. (anti-cancers.com)
  • Analysis of PTEN complex assembly and identification of heterogeneous nuclear ribonucleoprotein C as a component of the PTEN-associated complex. (immuquest.com)
  • Significant changes associated with domestication include pronounced synchronization of fiber development in G. hirsutum relative to other taxa studied, implicating unconscious selection that shaped early molecular and cellular events, and a delay in some developmental features in fibers of G. herbaceum, including delayed vacuole formation and nuclear migration. (iastate.edu)
  • We examined structure-activity relationships between 1 and its analogs and found that the carbonyl group at C-3 was essential for cytotoxicity. (nature.com)
  • D(490 nm) was measured by MTT assay to compared the cell proliferation of HUVECs after incubation for 12 h, 24 h and 48 h in each group. (shsmu.edu.cn)