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  • clinical
  • Is there an indication for serologic testing for human herpesvirus 8 (HHV-8) in asymptomatic HIV-infected children (compared with not testing) to guide clinical management? (nih.gov)
  • glycoprotein
  • Here, we show that both vIL-6 and VKORC1v2 interact with calnexin cycle proteins UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1), catalyzing monoglucosylation of N-glycans, and oppositely-acting glucosidase II (GlucII) and that vIL-6 can promote protein folding. (physiciansweekly.com)
  • isolates
  • Phenotypic and genetic polymorphisms among human herpesvirus-6 isolates from North American infants. (nih.gov)
  • All isolates replicated efficiently in primary human cord blood mononuclear cells, but five distinct patterns of viral replication in human cells lines were observed. (nih.gov)
  • These data suggest that not all HHV-6 isolates can be categorized into one of two broad groups and that such segregation of HHV-6 isolates may in fact be misleading. (nih.gov)
  • novel
  • In this study, we found novel pathways for HHV-6 assembly and release from T cells that differed, in part, from those of alphaherpesviruses. (ovid.com)
  • assays
  • Comparison of the multiplex assay with the respective single PCR assays using cloned HHV-6 and HHV-7 sequences as targets for amplification demonstrated equivalent sensitivities and specificities of the assays. (asmscience.org)
  • symptoms
  • HHV-6 infection can also present symptoms of gastroenteritis. (oup.com)
  • In addition, none of the five cases with HHV-6 DNA detected in CSF samples had any other identified cause of their CNS symptoms, and none of the other 11 cases with known. (oup.com)
  • In addition, none of the five cases with HHV-6 DNA detected in CSF samples had any other identified cause of their CNS symptoms, and none of the other 11 cases with known causes for their CNS diseases had HHV-6 DNA detected in CSF samples ( P = .03, Fisher's exact test). (oup.com)