• Atypical patterns of human cytomegalovirus infection and spread in U373 glioblastoma cells. (uc.edu)
  • Rescue of Pentamer-Null Strains of Human Cytomegalovirus in Epithelial Cells by Use of Histone Deacetylase Inhibitors Reveals an Additional Postentry Function for the Pentamer Complex. (uc.edu)
  • Human cytomegalovirus G protein-coupled receptor US28 promotes latency by attenuating c-fos. (uc.edu)
  • Development of a Primary Human Cell Model for the Study of Human Cytomegalovirus Replication and Spread within Salivary Epithelium. (uc.edu)
  • Human cytomegalovirus (HCMV) is a member of the β-herpesvirus subfamily of the Herpesviridae , with a high seroprevalence in the global human population via direct contact with bodily secretions, ranging from 50% in industrialized countries to as high as 99% in resource-poor communities and developing countries. (databasefootball.com)
  • Human Cytomegalovirus (CMV) is a member of the family Herpesviridae, also known as Human Herpesvirus 5 (HHV-5). (medscape.com)
  • Recently, the human herpesvirus cytomegalovirus (CMV) has been suggested to have an oncogenic role, yet this association remains controversial. (gwu.edu)
  • Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease. (cathdb.info)
  • They are characterized by a highly pressurized pseudo-icosahedral capsid-with triangulation number (T) equal to 16-encapsidating a tightly packed double-stranded DNA (dsDNA) genome 1-3 . (rcsb.org)
  • A key process in the herpesvirus life cycle involves the recruitment of an ATP-driven terminase to a unique portal vertex to recognize, package and cleave concatemeric dsDNA, ultimately giving rise to a pressurized, genome-containing virion 4,5 . (rcsb.org)
  • Although this process has been studied in dsDNA phages 6-9 -with which herpesviruses bear some similarities-a lack of high-resolution in situ structures of genome-packaging machinery has prevented the elucidation of how these multi-step reactions, which require close coordination among multiple actors, occur in an integrated environment. (rcsb.org)
  • To better define the structural basis of genome packaging and organization in herpes simplex virus type 1 (HSV-1), we developed sequential localized classification and symmetry relaxation methods to process cryo-electron microscopy (cryo-EM) images of HSV-1 virions, which enabled us to decouple and reconstruct hetero-symmetric and asymmetric elements within the pseudo-icosahedral capsid. (rcsb.org)
  • This work showcases how to resolve symmetry-mismatched elements in a large eukaryotic virus and provides insights into the mechanisms of herpesvirus genome packaging. (rcsb.org)
  • HCMV exemplifies the canonical architecture of herpesviruses, with an icosahedral capsid enclosing a double-stranded DNA (dsDNA) genome, a partially-ordered tegument layer, and a pleomorphic envelope bearing glycoproteins essential for host-cell entry. (databasefootball.com)
  • HCMV is the most genetically complex and, structurally, the largest among all human herpesviruses, with a genome of 235 kb and with a size exceeding 2000Å. (databasefootball.com)
  • It is the largest (220 nm in diameter) and most complex herpesvirus, with a 235,000 double-stranded DNA genome. (medscape.com)
  • The protein kinase complement of the human genome. (nih.gov)
  • The human genome contains about 20,000 protein-coding genes, but the coding parts of our genes account for only about 2 percent of the entire genome. (phys.org)
  • The example that probably leaps first into people's minds is the human microbiome: the more that is discovered about important microbes living on and in us, the more the concepts of 'me'/'my'/'mine' (e.g., my body, my genome, my behavior) become hazier (a sort of metaphysical Dunning-Kruger effect ? (asmblog.org)
  • Some are embedded within the human genome. (asmblog.org)
  • Of these, some are harmless, defanged by the passage of time, like the endogenous retroviruses that comprise 1-8% of the human genome or the ribozymes related to the Hepatitis D virus. (asmblog.org)
  • Herpesviruses consist of a double-stranded DNA genome contained within a protein shell, termed the capsid, that is surrounded by an unstructured protein layer and a lipid-envelope. (lu.se)
  • We recently discovered a high internal DNA pressure of tens of atmospheres in HSV-1 capsids, resulting from tight genome confinement and repulsive DNA-DNA interactions. (lu.se)
  • Two critical pieces of evidence are needed to incriminate these viruses as causing cancer in humans: 1) laboratory demonstration of ALSV integrated within the human genome, and 2) epidemiologic evidence of excess cancer occurrence in human exposed to these viruses. (cdc.gov)
  • The chromosomal localization of genes was improved, and Human Genome Variation Society (HGVS) notation was used throughout for translocations, insertions, and other gene alterations. (who.int)
  • Human herpesvirus 8 (HHV-8) is the infectious etiologic agent associated with Kaposi sarcoma, primary effusion lymphoma, and multicentric Castleman disease. (cdc.gov)
  • O sarcoma de Kaposi é a neoplasia mais diagnosticada em pacientes com SIDA e a expressão do antígeno nuclear latente-1 do herpesvírus humano tipo-8 (HHV-8) tem se mostrado útil no seu diagnóstico histológico. (fiocruz.br)
  • Positividade à imuno-histoquímica para o antígeno nuclear latente 1 do HHV-8 foi observada nos 49 casos de sarcoma de Kaposi e nenhuma reação foi detectada nos 60 simuladores analisados, resultando em 100% de sensibilidade e especificidade. (fiocruz.br)
  • The viruses Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) have been linked to several cancers. (scienceblog.com)
  • Similar to other herpesviruses, HHV-6 infects a wide variety of cells and remains latent after initial infection. (medscape.com)
  • Kaposi's sarcoma is the most common neoplasia diagnosed in AIDS patients and the expression of the human herpesvirus-8 (HHV-8) latent nuclear antigen-1 has been useful for its histological diagnosis. (fiocruz.br)
  • Antibody reactivity to latent and lytic antigens to human herpesvirus-8 in longitudinally followed homosexual men. (cdc.gov)
  • Latent class analysis of human herpesvirus 8 assay performance and infection prevalence in sub-Saharan Africa and Malta. (cdc.gov)
  • Like other human herpesviruses, HCMV is never completely cleared and remains latent throughout the life of the host once infected. (databasefootball.com)
  • After initial infection, all herpesviruses remain latent within specific host cells and may subsequently. (merckmanuals.com)
  • Herpesviruses establish latent permanent infections in their hosts, although clinical signs of disease may not be detected. (medscape.com)
  • [ 1 , 3 ] HHV-6 was isolated in 1986 during attempts to find novel viruses in patients with lymphoproliferative diseases. (medscape.com)
  • Upon infection many viruses, including Herpesviruses, target T cell function via specific interactions with TCR and HLA-I molecules. (frontiersin.org)
  • Herpesvirus simiae (B virus) is a member of the herpes group of viruses that is enzootic in rhesus (Macaca mulatta), cynomolgus (M. fascicularis) and other Asiatic monkeys of the genus Macaca. (cdc.gov)
  • The results help us to better understand how these viruses evolved and found their way into humans. (medindia.net)
  • Understanding where our viruses come from will help guide us in preventing future viruses from making the jump into humans", lead researcher Joel Wertheim said. (medindia.net)
  • This group of viruses includes human immunodeficiency virus (HIV), the immunodeficiency viruses of apes and monkeys (SIV), goats (CAEV), cats (FIV) and cattle (BIV). (ca.gov)
  • When you hear the word herpes virus, herpes simplex viruses 1 and 2 probably come immediately to mind. (healthline.com)
  • Herpesviruses are enveloped viruses that are prevalent in the human population and are responsible for diverse pathologies, including cold sores, birth defects and cancers. (rcsb.org)
  • For the first time, UNC School of Medicine scientists have discovered that these viruses use a human protein called barrier-to-autointegration factor 1, or BAF, to evade our innate immune response, allowing the viruses to spread and cause disease. (scienceblog.com)
  • Viruses have evolved with humans for millions of years, so it's no surprise they've evolved tricks to evade our natural, or innate, immune responses. (scienceblog.com)
  • The human herpes viruses (HHV) take part of a virus family - Herpesviridae- and these viruses have human as only host. (bvsalud.org)
  • This paper is a review about the human herpes viruses types, their treatments and emphasizes their oral manifestations. (bvsalud.org)
  • Herpesvirus family members are icosahedral DNA viruses. (medscape.com)
  • These include the retroviruses avian leucosis/sarcoma viruses (ALSV) and reticuloendothesiosis viruses (REV), and the herpesvirus Marek's disease virus (MDV). (cdc.gov)
  • These viruses have been shown to be capable of infecting human cells in vitro, and causing them to become cancerous. (cdc.gov)
  • Human exposure to these viruses occur occupationally (workers in poultry slaughtering/processing plants and poultry farms, egg candlers, veterinarians, cooks, laboratory workers, etc. (cdc.gov)
  • However, in spite of the scientific evidence accumulated thus far, definitive proof that can confirm beyond any doubt that these viruses cause cancer in humans is currently lacking. (cdc.gov)
  • Their fundamental role in anti-viral responses has been unveiled in patients with NK cell deficiencies suffering from severe Herpesvirus infections. (frontiersin.org)
  • This lifelong challenge has contributed to the development of numerous evasion mechanisms by Herpesviruses, many of which devoted to elude NK cell surveillance from viral reactivations rather than primary infections. (frontiersin.org)
  • They may also have a possible relationship with chronic viral infections, such as human herpesvirus (HHV), and especially Epstein-Barr virus (EBV), which causes several medical conditions. (thejns.org)
  • Overview of Herpesvirus Infections Eight types of herpesviruses infect humans ( see Table: Herpesviruses That Infect Humans). (merckmanuals.com)
  • Famciclovir is a human antiviral agent used in the treatment of Feline Herpes (FHV-1) infections. (medi-vet.com)
  • Panel on Sexually Transmitted Infections including those due to Human Immunodeficiency Virus, was posted on the WHO web site in February 2006 for a discussion and submission of comments by Member States. (who.int)
  • Members of the human herpesvirus (HHV) and human papillomavirus (HPV) families cause the most common primary viral infections of the oral cavity. (medscape.com)
  • Nonetheless, many other viral infections can affect the oral cavity in humans, either as localized or systemic infections. (medscape.com)
  • In HHV-1 and HHV-2 oral infections, viral replication within the oral epithelium may cause lysis of epithelial cells, with vesicle formation. (medscape.com)
  • The type species of SIMPLEXVIRUS causing most forms of non- genital herpes simplex in humans . (online-medical-dictionary.org)
  • Genital herpes is a sexually transmitted infection caused by human herpesvirus 1 or 2. (merckmanuals.com)
  • Herpes simplex virus-1 (HSV-1) and herpes simplex virus-2 (HSV-2) cause oral and genital herpes, and varicella-zoster virus causes chickenpox in children and shingles later in life. (lifeextension.com)
  • HHV-2, also known as HSV-2, causes genital herpes and occasionally causes oral disease that is clinically similar to that of HHV-1 infection. (medscape.com)
  • A vital part of the normal mechanism of HSV-1, the ICP34.5 protein has been proposed to condition post-mitotic cells for viral replication. (wikipedia.org)
  • The article shows how the virus interacts with a receptor on human cells, the EphA2 receptor, via a surface protein complex made of glycoproteins H and L (gH/gL). (pasteur.fr)
  • The herpes simplex virus type 1 (HSV-1) glycoprotein N (gN/UL49.5) is a type I transmembrane protein conserved throughout the herpesvirus family. (mdpi.com)
  • Among the tens of glycoproteins, three - glycoprotein B (gB), which functions as a fusion protein, and glycoprotein H/glycoprotein L (gH/gL) complex, which functions as a receptor-binding protein - are conserved across all herpesviruses, forming the core viral fusion machinery. (databasefootball.com)
  • Led by Gregory Smith, associate professor in immunology and microbiology at Northwestern University Feinberg School of Medicine, researchers found that viral protein 1-2, or VP1/2, allows the herpesvirus to interact with cellular motors, known as dynein. (sciencedaily.com)
  • Yet the herpesvirus uses one protein, no others required, to transport its genetic information over long distances without stopping. (sciencedaily.com)
  • So, the spike protein binds to the ACE2 receptor once it's produced by the human cell … but it's a modified version of the spike protein. (fromthetrenchesworldreport.com)
  • To summarize the seroprevalence of human herpesvirus 8 (HHV-8) in mainland China, we conducted a systematic review and meta-analysis based on available literature. (cdc.gov)
  • Worldwide seroprevalence of HHV-8 varies: generally low to moderate for populations in Western countries and Asia ( 1 - 4 ) but as high as 50% for the general population in sub-Saharan Africa and higher for HIV-positive populations ( 5 - 7 ). (cdc.gov)
  • HHV-6 was the sixth herpesvirus discovered, and infection in humans is nearly ubiquitous in the first two years of life, with seroprevalence rates surpassing 95% in most studies. (medscape.com)
  • HHV-1: The seroprevalence is approximately 80% in North American adults. (medscape.com)
  • Human herpesvirus multiplex ddPCR detection in brain tissue from low- " by Cheng-Te Major Lin, Emily C Leibovitch et al. (gwu.edu)
  • Human herpesvirus multiplex ddPCR detection in brain tissue from low- and high-grade astrocytoma cases and controls. (gwu.edu)
  • Detection of human herpesvirus-6 transcripts in carbamazepine-induced hypersensitivity syndrome by in situ hybridization. (qxmd.com)
  • A study in which the Structural Virology team at the Institut Pasteur participated investigates the way this herpesvirus manages to infect human cells. (pasteur.fr)
  • It is caused by human herpesviruses 1 (HSV-1) or 2 (HSV-2), which are two of the eight types of herpesviruses that infect humans. (merckmanuals.com)
  • One of the better studied examples is Ectocarpus siliculosus virus-1, which is able to infect both the zoospores required for asexual reproduction and the gametes required for sexual reproduction, but is only able to multiply in the algal reproductive organs. (asmblog.org)
  • Infection with human papillomavirus increases the probability of developing carcinoma of the cervix, which is the second leading cause of cancer- related mortality in females worldwide, killing some 240 000 women per year.1 Making a correct diagnosis of a sexually transmitted infection is essential for the provision of appropriate and effective treatment. (who.int)
  • A close relationship was found between this property and infection with the type 2 strains and it is hoped that this observation may be used as a simple and reliable biological marker for the differentiation of HVH type 1 and type 2. (microbiologyresearch.org)
  • Differentiation between herpes simplex virus type 1 and type 2 strains by immunoelectro-osmophoresis. (microbiologyresearch.org)
  • Investigation of plaque formation in chick embryo cells as a biological marker for distinguishing herpes virus type 2 from type 1. (microbiologyresearch.org)
  • Relation of pock size on chorioallantoic membrane to antigenic type of herpesvirus hominis. (microbiologyresearch.org)
  • Deng, Y., Jing, Y., Campbell, A. E. & Gravenstein, S. Age-related impaired type 1 T cell responses to influenza: reduced activation ex vivo , decreased expansion in CTL culture in vitro , and blunted response to influenza vaccination in vivo in the elderly. (nature.com)
  • Human herpesvirus (HHV) type 3. (medscape.com)
  • CMV is a type of herpesvirus. (healthline.com)
  • The other family members include herpes simplex virus type 1 (HSV-1 or HHV-1) and herpes simplex virus type 2 (HSV-2 or HHV-2), varicella zoster virus (VZV), human herpes virus (HHV)-6, HHV-7, and HHV-8. (medscape.com)
  • Evidence linking sunlight, vitamin D, and the risk of multiple sclerosis and type 1 diabetes is summarized to develop the thesis that vitamin D is the environmental factor that most strongly influences autoimmune disease development. (frontiersin.org)
  • Animal modeling and human mechanistic data are summarized to support the view that vitamin D probably influences thymic negative selection, effector Th1 and Th17 pathogenesis and responsiveness to extrinsic cell death signals, FoxP3 + CD4 + T-regulatory cell and CD4 + T-regulatory cell type 1 (Tr1) cell functions, and a Th1-Tr1 switch. (frontiersin.org)
  • The global burden has risen with the near tripling in the last half-century of multiple sclerosis (MS) ( 2 , 3 ), type 1 diabetes (T1D) ( 4 ), and other autoimmune diseases. (frontiersin.org)
  • Herpes Simplex virus type 1 (HSV-1) is a prototypical model system to study the general infection mechanisms of herpesviruses. (lu.se)
  • Sensitivity and specificity of the orf73 ELISA have not been established, although the widely used indirect immunofluorescence assay for LANA antibodies has reasonable but perhaps more variable sensitivity (80-100%) and specificity (57-100%) (1;3). (cdc.gov)
  • The major mechanisms of recognition and effector responses employed by NK cells against Herpesviruses, related to their genomic organization will be addressed, including those allowing NK cells to generate memory-like responses. (frontiersin.org)
  • After a prodromal illness of pain and paresthesias, erythematous macules and papules develop and progress to vesicles in 1-2 days. (medscape.com)
  • In order to better treat this disease, it is essential to understand the functioning of Kaposi's sarcoma-associated herpesvirus (KSHV), which causes it. (pasteur.fr)
  • How does the Kaposi's sarcoma herpesvirus enter the cell? (pasteur.fr)
  • The Kaposi's sarcoma herpesvirus causes skin cancers, especially in immunocompromised people. (pasteur.fr)
  • Scientists call it human herpesvirus-5 (HHV-5). (healthline.com)
  • Scientists have identified a component of the herpesvirus that "hijacks" machinery inside human cells, allowing the virus to rapidly and successfully invade the nervous system upon initial exposure. (sciencedaily.com)
  • Until now, scientists knew that herpesviruses travel quickly to reach neurons located deep inside the body, but the mechanism by which they advance remained a mystery. (sciencedaily.com)
  • Regional distribution of pooled human herpesvirus 8 (HHV-8) prevalence in A) the general population and B) immunocompromised patients, China. (cdc.gov)
  • Prevalence is es- timated to be 1.67/10 000 population in the Islamic Republic of Iran [ 1 ]. (who.int)
  • G207 was constructed as a second-generation vector from HSV-1 laboratory strain F, with ICP34.5 deleted and the ICP6 gene inactivated by insertion of the E. coli LacZ gene. (wikipedia.org)
  • EHM is most often due to the neuropathologic strain of EHV-1, but may occasionally be caused by the non-neurologic strains of the virus. (ca.gov)
  • Seventeen additional cases of B virus infection in humans were described through 1973 (2)* and four cases, including the first known case of person-to-person transmission of the virus, occurred in Pensacola, Florida, in 1987 (5). (cdc.gov)
  • This extreme degree of morbidity and mortality has given the impression that B virus infection in humans nearly always results in severe or fatal disease. (cdc.gov)
  • As with herpes simplex virus I infection in humans, primary infection with B virus in macaques may result in gingivostomatitis with characteristic buccal mucosal lesions, but it probably occurs frequently without such signs. (cdc.gov)
  • Except for one instance of person-to-person transmission, however, all cases of B virus infection in humans have occurred in persons exposed to monkeys or monkey tissues. (cdc.gov)
  • L'aphtose buccale (93,8 %), l'aphtose génitale (77,1 %) et les manifestations ocu- laires (64,6 %) constituaient les principales constatations physiques. (who.int)
  • HveA (formerly HVEM) is a member of the tumor necrosis factor receptor family, whereas the poliovirus receptor-related proteins 1 and 2 (PRR1 and PRR2, renamed HveC and HveB) belong to the immunoglobulin superfamily. (nih.gov)
  • A recent study offers new modellings of one of the virus' a surface proteins, and its receptor, on human cells. (pasteur.fr)
  • However, the rules for common sites of occurrence of HHV-1 and HHV-3 often do not apply to patients who are immunocompromised. (medscape.com)
  • In formulating these guidelines, the working group recognizes that other methods of caring for nonhuman primates and preventing transmission of pathogenic agents from animal to human and from human to animal have been described (6,7). (cdc.gov)
  • The purpose of the working group was to supplement existing methods with specific guidelines intended to minimize transmission of B virus infection from macaque monkeys to humans. (cdc.gov)
  • The human body is composed of billions of cells, each of which is made and maintained through countless interactions among its molecular parts. (phys.org)
  • Clinical and Molecular Epidemiology of Crimean-Congo Hemorrhagic Fever in Humans in Uganda, 2013-2019. (cdc.gov)
  • Consequently, the mechanism underlying the process of receptor-triggered membrane fusion remains poorly understood for not only HCMV but also for other herpesviruses. (databasefootball.com)
  • Using BCBL-1 cells that harbour HHV-8 but lack Epstein-Barr virus, we demonstrate that sodium butyrate is much more effective than the phorbol ester 12-O-tetradecanoyl phorbol-13-acetate (TPA) at inducing high levels of class II and III virus transcription and viral DNA replication, but also initiates apoptosis. (houstonmethodist.org)
  • Apoptosis occurs prior to assembly of virions when high concentrations of butyrate (1-3 mM) are used, whereas reduction of butyrate concentration to 0.3 mM decreases the rate of apoptosis and results in production and secretion of enveloped virions that are visualized at high number by electron microscopy in approximately 20% of BCBL-1 cells. (houstonmethodist.org)
  • Here we show that co-engagement of CD3 and the complement regulator CD46 in the presence of IL-2 induces a Tr1-specific cytokine phenotype in human CD4 + T cells. (nature.com)
  • Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers. (uc.edu)
  • Human CMV grows only in human cells and replicates best in human fibroblasts. (medscape.com)
  • The team studied the herpesvirus in animals, and also in human and animal cells in culture under high-resolution microscopy. (sciencedaily.com)
  • Even now, laboratories are working on how to use herpesviruses to deliver genes into the nervous system and kill cancer cells. (sciencedaily.com)
  • Twenty-four strains of Herpesvirus hominis (HVH) were tested for their ability to produce large focal necrotic lesions in the liver of mice inoculated intraperitoneally with herpes virus. (microbiologyresearch.org)
  • A temperature marker test for differentiation of strains of herpesvirus hominis. (microbiologyresearch.org)
  • Infection by herpesviruses leads to many human diseases, ranging from a cold sore, chickenpox, to cancer. (databasefootball.com)
  • Using HSV-1 as our primary model system, you will investigate the roles of internal DNA pressure for viral replication. (lu.se)
  • It is based on the herpes simplex virus (HSV-1). (wikipedia.org)
  • However, the constant stimulus provided by virus-host interplay has also favored NK-cell adaptation to Herpesviruses. (frontiersin.org)
  • The report of a case of encephalitis caused by B virus in a monkey handler in 1932 indicated that B virus can be highly pathogenic for humans (1). (cdc.gov)
  • B virus-related disease is characterized by a variety of symptoms, which generally occur within 1 month of exposure. (cdc.gov)
  • Researchers at University of California, San Diego, suggest that the ancestors of modern humans may have caught herpes virus from chimpanzees before going their separate ways on the evolution path. (medindia.net)
  • According to the study, the ancestors of modern humans were infected by the Herpes Simplex Virus-1 from chimpanzees more than 6 million years ago, before the evolutionary split, while Herpes Simplex Virus-2, which causes genital warts, jumped from chimpanzees to Homo erectus 1.6 million years ago, long before the rise of early modern humans. (medindia.net)
  • Equine Herpes Virus-1 (EHV-1) infection in horses can cause respiratory disease, abortion in mares, neonatal foal death and neurological disease. (ca.gov)
  • he virus is not transmissible to humans. (ca.gov)
  • Australian Register of Therapeutic Goods (ARTG) information for Abbott Australasia Pty Ltd Diagnostic Division - Herpes simplex virus (HSV) (Human herpesvirus 1 & 2) IVDs. (tga.gov.au)
  • In addition, human herpesvirus 6 (HHV-6) and Epstein-Barr virus (EBV) have also been associated with low-grade gliomas, but few studies have examined HHV-6 and EBV in glioblastomas. (gwu.edu)
  • The virus can live dormant in humans for a lifetime, and most infected people do not know they are disease carriers. (sciencedaily.com)
  • HHV-1, also known as herpes simplex virus (HSV)-1, causes primary herpetic gingivostomatitis, or oral herpes. (medscape.com)
  • HCMV virions were collected from the cultured human fibroblasts, rapidly frozen in vitreous ice, and imaged in Titan Krios, the world's most powerful transmission electron microscope. (databasefootball.com)
  • The disease is not known to affect humans or other species of livestock. (ca.gov)
  • The disease can also affect many other species of animals and has occurred in sheep, goats, wildlife and occasionally humans. (ca.gov)
  • According to the Centers for Disease Control and Prevention (CDC) , 1 in 3 children has contracted CMV by age 5. (healthline.com)
  • Human herpesvirus-8 (HHV-8) is a gammaherpesvirus that is present primarily in a state of low level persistence in primary effusion lymphoma cell lines. (houstonmethodist.org)
  • The HSV 1 and 2 are usually associated to Primary Herpetic Gingivostomatitis, Recurrent Labial Herpes and Reccurent Intra-Oral Herpes. (bvsalud.org)