Inhalation ExposureHeroin DependenceAdministration, InhalationAerosolsToxicity Tests, AcuteAtmosphere Exposure ChambersNasal CavityRats, Inbred F344Organ SizeParticle SizeDose-Response Relationship, DrugSmoke Inhalation InjuryBody WeightBurns, InhalationNarcoticsInhalationToxicity TestsMorphine DerivativesMethadoneSelf AdministrationDrug OverdoseAnesthetics, InhalationLungBuprenorphinePowdersAnesthesia, InhalationCodeineStreet DrugsCocaine-Related DisordersTime FactorsSubstance Abuse, IntravenousBronchial Provocation TestsSubstance Abuse DetectionBehavior, AddictiveOpioid-Related DisordersDrug Administration ScheduleAsthmaSubstance Withdrawal SyndromeLethal Dose 50Drug and Narcotic ControlBronchodilator AgentsTreatment OutcomeMorphineAlbuterolSubstance-Related DisordersNaloxoneCocaineAir Pollutants, OccupationalOpiate Substitution TreatmentNaltrexoneDry Powder InhalersBronchoalveolar Lavage FluidReceptors, Opioid, muXenon RadioisotopesNo-Observed-Adverse-Effect LevelInjections, IntravenousInhalation SpacersAntineoplastic Combined Chemotherapy ProtocolsAnalgesics, OpioidAir PollutantsForced Expiratory VolumeToxicity Tests, ChronicMethacholine ChlorideRats, Sprague-DawleyAdministration, OralAnthraxDrug UsersRespirationAirway ResistanceAntineoplastic AgentsSmokeIsocyanatesBronchoconstrictionDisease Models, AnimalBurnsBronchiGas Chromatography-Mass SpectrometryOccupational ExposureCarboxyhemoglobinTrichloroethanesMetered Dose InhalersDustToxicologyRespiratory Function TestsDrug InteractionsConditioning, OperantBronchial HyperreactivityRespiratory TherapyInfusions, IntravenousCrimeNitrous OxideRespiratory SystemCromolyn SodiumOxygen Inhalation TherapyOxygen RadioisotopesCarbon DioxideBronchoconstrictor AgentsNucleus AccumbensBehavior, AnimalPlutonium