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Anatomy16

Oocytes HEK293 Cells CHO Cells Cell Line Myocytes, Cardiac Skeletal Muscle Ventricle Heart Muscle Cells Cell Membrane Myocardium Heart Ventricles Cells, Cultured Extracellular Fluid Kidney Intracellular Space Endoplasmic Reticulum

Organisms8

Xenopus laevis Xenopus Cricetinae Lindera Cricetulus Guinea Pigs Scorpions Rabbits

Diseases7

Long QT Syndrome Torsades de Pointes Tachycardia, Reciprocating Hypokalemia Lipidoses Drug-Related Side Effects and Adverse Reactions Death, Sudden, Cardiac

Chemicals and Drugs83

Ether-A-Go-Go Potassium Channels Potassium Channels, Voltage-Gated Cation Transport Proteins Potassium Channels Potassium Channel Blockers Cisapride Astemizole Terfenadine Trans-Activators KCNQ1 Potassium Channel Phenethylamines Anti-Arrhythmia Agents Quinidine KCNQ Potassium Channels DNA-Binding Proteins Piperidines Potassium Delayed Rectifier Potassium Channels RNA, Complementary Sulfanilamides Propafenone Histamine H1 Antagonists Sulfonamides Kv1.5 Potassium Channel Cresols Pentamidine Pyridines Benzopyrans Bepridil Scorpion Venoms Promazine Chlorobenzenes Loratadine Doxepin Histamine H1 Antagonists, Non-Sedating Cardiac Glycosides Dextropropoxyphene Probucol Ketoconazole Quinolines Imidazolidines Protein Isoforms Cetirizine Nucleotides, Cyclic Amino Acids, Aromatic Recombinant Proteins Quaternary Ammonium Compounds Fluvoxamine NAV1.5 Voltage-Gated Sodium Channel Hydroxyzine Thallium Gastrointestinal Agents Antidepressive Agents, Tricyclic Flecainide 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone Benzyl Compounds Canrenoic Acid Endosomal Sorting Complexes Required for Transport Benzimidazoles Amitriptyline Amiodarone Ions Cnidarian Venoms Fluoxetine ortho-Aminobenzoates Cyclic AMP-Dependent Protein Kinases Codon, Nonsense Antipsychotic Agents Sodium Cyanide Phenylurea Compounds Maleimides Shaw Potassium Channels Shaker Superfamily of Potassium Channels HSC70 Heat-Shock Proteins Dynamin II rab4 GTP-Binding Proteins Phosphatidylinositol 4,5-Diphosphate Sodium Channels Mexiletine Phenylalanine Lanthanum Miconazole 14-3-3 Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Patch-Clamp Techniques Inhibitory Concentration 50 Mutagenesis, Site-Directed Transfection Amino Acid Substitution Skeletal Muscle Ventricle Models, Cardiovascular Models, Molecular Electrocardiography Drug Evaluation, Preclinical Nuclease Protection Assays Models, Biological Blotting, Western Electric Stimulation Markov Chains High-Throughput Screening Assays

Phenomena and Processes37

Ion Channel Gating Membrane Potentials Mutation Action Potentials Inhibitory Concentration 50 Dose-Response Relationship, Drug Mutation, Missense Transfection Electric Conductivity Protein Transport Amino Acid Substitution Kinetics Protein Structure, Tertiary Structure-Activity Relationship Amino Acid Sequence Binding Sites Electrophysiological Phenomena Quantitative Structure-Activity Relationship Hydrophobic and Hydrophilic Interactions Gene Expression Protein Conformation Point Mutation Nonsense Mediated mRNA Decay Protein Modification, Translational Protein Stability Frameshift Mutation Time Factors Codon, Nonsense Sequence Homology, Amino Acid Mutagenesis Protein Binding Temperature Electrophysiological Processes Protein Structure, Secondary Markov Chains Genes, Dominant Polymorphism, Single-Stranded Conformational

Disciplines and Occupations2

Electrophysiology Biophysics

Anthropology, Education, Sociology and Social Phenomena1

Information Science3

Molecular Sequence Data Amino Acid Sequence Computer Simulation

Health Care3

Drug Recalls Temperature Markov Chains

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Anthropology, Education, Sociology and Social Phenomena Information Science Health Care

Ether-A-Go-Go Potassium Channels Potassium Channels, Voltage-Gated Cation Transport Proteins Long QT Syndrome Potassium Channels Potassium Channel Blockers Cisapride Astemizole Patch-Clamp Techniques Terfenadine Trans-Activators KCNQ1 Potassium Channel Ion Channel Gating Xenopus laevis Oocytes Phenethylamines Anti-Arrhythmia Agents Membrane Potentials Quinidine KCNQ Potassium Channels Xenopus DNA-Binding Proteins Piperidines HEK293 Cells Torsades de Pointes CHO Cells Mutation Electrophysiology Potassium Action Potentials Delayed Rectifier Potassium Channels RNA, Complementary Sulfanilamides Cell Line Propafenone Cricetinae Histamine H1 Antagonists Sulfonamides Kv1.5 Potassium Channel Myocytes, Cardiac Inhibitory Concentration 50 Dose-Response Relationship, Drug Mutagenesis, Site-Directed Lindera Mutation, Missense Transfection Cricetulus Cresols Pentamidine Pyridines Benzopyrans Electric Conductivity Bepridil Scorpion Venoms Protein Transport Promazine Guinea Pigs Amino Acid Substitution Tachycardia, Reciprocating Chlorobenzenes Loratadine Doxepin Kinetics Protein Structure, Tertiary Skeletal Muscle Ventricle Structure-Activity Relationship Heart Molecular Sequence Data Histamine H1 Antagonists, Non-Sedating Drug Recalls Cardiac Glycosides Muscle Cells Models, Cardiovascular Hypokalemia Amino Acid Sequence Dextropropoxyphene Models, Molecular Electrocardiography Cell Membrane Probucol Myocardium Drug Evaluation, Preclinical Ketoconazole Quinolines Imidazolidines Binding Sites Heart Ventricles Protein Isoforms Cetirizine Nucleotides, Cyclic Amino Acids, Aromatic Recombinant Proteins Quaternary Ammonium Compounds Fluvoxamine Electrophysiological Phenomena NAV1.5 Voltage-Gated Sodium Channel Hydroxyzine Thallium Gastrointestinal Agents Antidepressive Agents, Tricyclic

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