• Myocardial hypertrophy is defined as a thickening of the myocardium, which results in a decrease in the size of the chamber of the heart, including the left and right ventricles, and is an important risk factor for subsequent cardiac morbidity and mortality. (scielo.br)
  • The strong affinity of HGF for heparin was exploited as a major enrichment step in many of the purification schemes (1-6, 11), and the interaction between HGF and this ubiquitous extracellular matrix component may play an important role in HGF sequestration and signaling, as has been demonstrated for members of the fibroblast growth factor family (reviewed in 12). (springer.com)
  • Boccaccio C, Comoglio PM. MET, a driver of invasive growth and cancer clonal evolution under therapeutic pressure. (springer.com)
  • Summary: We explored relations between serum hepatocyte growth factor (HGF), disease activity, osteoproliferation, and bone mineral density (BMD) in ankylosing spondylitis (AS), in comparison with healthy controls. (diva-portal.org)
  • The aims of this study were to compare serum levels of hepatocyte growth factor (HGF), matrix metalloproteinase-3 (MMP-3), and vascular endothelial growth factor (VEGF) in AS patients with healthy controls (HC) and to explore the associations with disease activity, osteoproliferation, and bone mineral density (BMD). (diva-portal.org)
  • In addition, serum HGF was positively associated with risk factors for osteoproliferation such as age, CRP and smoking. (diva-portal.org)
  • Serum hepatocyte growth factor as a prognostic marker for stage II or III colorectal cancer patients. (nih.gov)
  • We previously reported that a combination of serum hepatocyte growth factor (HGF) and carcinoembryonic antigen (CEA) was useful for selecting early-stage colorectal cancer patients with aggressive disease. (nih.gov)
  • Elevated serum HGF level demonstrated a significant association with poor survival, and was only an independent risk factor for poor survival in Stage II or/and III. (nih.gov)
  • The transcriptional factors are activated by the primary messengers, in most cases, due to their function as nuclear receptors for these messengers. (wikipedia.org)
  • Several signaling pathways are known to stimulate regeneration in the liver including cytokines, growth factors, hormones, and nuclear receptors. (wikipedia.org)
  • At the same time, the embryonic mesenchymal cells around the epithelial bud receive secreting factors activated by PTHrP, such as BMP4. (wikipedia.org)
  • This is putatively mediated by autocrine or paracrine mechanisms that promote tumor cell growth, invasion and angiogenesis. (nih.gov)