- Hepatitis D virus (HDV), also known as delta hepatitis virus, is a defective RNA virus comprising of a delta antigen and a hepatitis B surface antigen (HBsAg) as the core and protein coat of the virus, respectively. (mayomedicallaboratories.com)
- Hepatitis D virus infection in HBsAg carriers can be present as a simultaneous and acute infection. (jrehabilhealth.com)
- Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg). (wikipedia.org)
- DIPA interacts with the viral antigen, HDAg, and can affect HDV replication in vitro. (wikipedia.org)
- Five of the ten patients scored positive for HDV RNA and negative for hepatitis delta antigen (HDAg) while one was negative for HDV RNA and positive for HDAg. (unifi.it)
- The same RNA probe enabled the detection of serum HDV RNA in 21/28 chronic hepatitis patients (liver HDAg and/or IgM anti-HD positive) (group II). (unifi.it)
- For prevention of HDV transmission, all patients of chronic hepatitis B with low-level viral load should be evaluated for hepatitis D infection. (jrehabilhealth.com)
- This infection simultaneously leads to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma ( 3 ). (jrehabilhealth.com)
- In comparison with patients with chronic hepatitis B, patients with chronic hepatitis B and D are significantly more likely to have cirrhosis and hepatocellular carcinoma. (jrehabilhealth.com)
- We have investigated the usefulness of serum hepatitis delta virus (HDV) RNA detection using a slot hybridization analysis of serum samples from ten patients with acute hepatitis and delta markers (group I), from 28 patients with chronic delta hepatitis (group II) and from seven liver graft recipients with hepatitis B virus (HBV) and HDV related cirrhosis or fulminant hepatitis (group III). (unifi.it)
- Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids. (wikipedia.org)
- This virus cannot replicate effectively by itself, and it requires the presence of hepatitis B virus (HBV) to initiate and maintain its replication in the infected liver cells. (mayomedicallaboratories.com)
- CONCLUSION Our data indicated that hepatitis delta virus isolates in Tehran are exclusively genotype I. (semanticscholar.org)
- Additional tests, such as hepatitis B core antibody IgM, are useful to determine if a Hepatitis Delta virus is co-infection or super-infection. (medichecks.com)
- Current prevalence of hepatitis delta virus (HDV) infection and the range of HDV genotypes in Lebanon. (semanticscholar.org)
- Bineshian F, Sharifi Z. The Prevalence of Hepatitis Delta Virus in Patients with Chronic Hepatitis B and Its Association with Risk Factors, Middle East J Rehabil Health Stud. (jrehabilhealth.com)
- Genotype analysis of hepatitis delta virus from hepatitis B surface antigen-positive patients using PCR-RFLP in Tehran, Iran. (semanticscholar.org)
- All polymorphisms were shown to be genotype I. Out of 13 hepatitis delta virus RNA-positive (13/35), eight were HBeAg negative. (semanticscholar.org)
- Clinical presentation and genotype of hepatitis delta in Karachi. (semanticscholar.org)
- The Hepatitis Delta Antigen test is used to diagnose hepatitis D infection in patients with documented acute or chronic hepatitis B and who at risk for Hepatitis Delta virus infection. (medichecks.com)
- Positive results usually indicate 1 of the following conditions: 1) simultaneous acute or chronic coinfection with hepatitis B virus (HBV) and HDV, 2) acute HDV infection in patients with known chronic HBV infection (ie, HDV superinfection), or 3) resolved HDV infection. (mayomedicallaboratories.com)
- Negative result may not rule out hepatitis D virus (HDV) infection during the early phase of infection or in immunocompromised patients who have delayed or inadequate immune response. (mayomedicallaboratories.com)
- Hepatitis delta virus requires the surface antigen of hepatitis B virus to replicate and transmit. (jrehabilhealth.com)
- HDV superinfection in chronic HBV or in HBV carrier state typically manifests as an acute exacerbation of chronic hepatitis B, with tendency to result in chronic HBV-HDV coinfection and early cirrhosis or liver failure. (mayomedicallaboratories.com)
- in patients with hepatitis B during year 1977 ( 2 ). (jrehabilhealth.com)
- Genetic heterogeneity of hepatitis viruses and its clinical significance. (semanticscholar.org)
- However, infection with HDV in patients with HBV (super-infection) usually causes chronic hepatitis due to both viruses. (jrehabilhealth.com)
- Delta antigen was identified by Rizzetto et al. (jrehabilhealth.com)
- METHODS In this study, hepatitis delta virus RNA of 35 patients' sera were analyzed by RT- semi-nested polymerase chain reaction. (semanticscholar.org)
- Based on genomic differences of hepatitis delta antigen coding region of hepatitis delta virus RNA among hepatitis delta virus RNA-positive sera, the polymerase chain reaction products were digested with restriction enzymes and studied by restriction fragment length polymorphism. (semanticscholar.org)
- RESULTS Out of 35 samples, 13 (38.46%) were positive for hepatitis delta virus RNA by RT- semi-nested polymerase chain reaction. (semanticscholar.org)
- This virus is dependent on hepatitis B virus for transmission and propagation. (semanticscholar.org)
- Hepatitis delta virus (HDV) genotypes in patients with chronic hepatitis: molecular epidemiology of HDV in Turkey. (semanticscholar.org)
- Hepatitis Delta infection cannot occur in the absence of hepatitis B infection. (medichecks.com)
- Hepatitis Delta virus (HDV) is a subviral agent that is dependent on the hepatitis B (HBV) virus for its life cycle. (medichecks.com)
- BACKGROUND Hepatitis delta virus is a unique human pathogen responsible for some 20 million infections globally. (semanticscholar.org)
- Acute hepatitis is a result of co-infection of HBV and HDV, which is usually associated with recovery from both HBV and HDV infections. (jrehabilhealth.com)
