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  • bilirubin
  • To be included in the study, the patients had to meet the following criteria for inclusion: having hepatic VOD (ie, bilirubin ≥2 mg/dL by day +21 post-hematopoietic SCT, and ≥2 of the following: ascites, weight gain ≥5%, or new-onset or worsening hepatomegaly) with multiorgan failure (ie, renal and/or pulmonary dysfunction by day +28 post-hematopoietic SCT). (jhoponline.com)
  • Total bilirubin, albumin and hepatic encephalopathy were independent prognostic markers of survival. (biomedcentral.com)
  • The presence of hepatic encephalopathy, serum bilirubin and albumin levels were major prognostic factors for Gynura segetum -induced HVOD. (biomedcentral.com)
  • bone
  • High-dose (10 mg/day) norethisterone has been associated with hepatic veno-occlusive disease, and because of this adverse effect, norethisterone should not be given to patients undergoing allogeneic bone marrow transplantation, as it has been associated with substantially lower one-year survival post-transplantation. (wikipedia.org)
  • The drug was noted to increase the risk of veno-occlusive disease in the absence of bone marrow transplantation. (wikipedia.org)
  • adults
  • Jazz Pharmaceuticals, Inc, Palo Alto, CA) for the treatment of adults and children with hepatic VOD who develop renal or pulmonary dysfunction after undergoing hematopoietic SCT. (jhoponline.com)
  • Acute leukemias in both adults and children Chronic myelogenous leukemia Inflammatory bowel disease, especially ulcerative colitis Psoriasis Leukopenia and neutropenia Thrombocytopenia Anemia Anorexia Nausea and vomiting Hepatotoxicity: this manifests as: The major concern that has inhibited the use of thioguanine has been veno-occlusive disease (VOD) and its histological precursor nodular regenerative hyperplasia (NRH). (wikipedia.org)
  • portal vein
  • This may reveal the size and shape of the abdominal organs, and Doppler studies may show the direction of flow in the portal vein, as well as detecting Budd-Chiari syndrome (thrombosis of the hepatic vein) and portal vein thrombosis. (wikipedia.org)
  • Roughly, transudates are a result of increased pressure in the hepatic portal vein (>8 mmHg, usually around 20 mmHg), e.g. due to cirrhosis, while exudates are actively secreted fluid due to inflammation or malignancy. (wikipedia.org)
  • Disorders
  • This includes mostly drug-induced hepatotoxicity, (DILI) which may generate many different patterns over liver disease, including cholestasis necrosis acute hepatitis and chronic hepatitis of different forms, cirrhosis Effects of Acetaminophen (Tylenol) other rare disorders like focal nodular hyperplasia, Hepatic fibrosis, peliosis hepatis and veno-occlusive disease. (wikipedia.org)
  • doses
  • This has been confirmed in human trials, where thioguanine has proven to be safe but efficacious for coeliac disease when used at doses below those commonly prescribed. (wikipedia.org)
  • Malignant
  • The most frequent forms are metastatic malignant neoplasm of liver) liver cell carcinoma hepatocellular carcinoma hepatoma cholangiocarcinoma hepatoblastoma angiosarcoma of liver Kupffer cell sarcoma other sarcomas of liver Benign neoplasm of liver include hepatic hemangiomas, hepatic adenomas, and focal nodular hyperplasia (FNH). (wikipedia.org)
  • mortality
  • Kakar has written and spoken internationally about numerous challenges faced in Afghanistan, including infectious disease epidemics, maternal mortality and the dangers of herbicides used to eradicate poppy. (wikipedia.org)
  • causes
  • The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). (wikipedia.org)
  • condition
  • Patient has a serious active disease or co-morbid medical condition, as judged by the investigator, which would interfere with the conduct of this study. (centerwatch.com)