• Aetna considers percutaneous ethanol injection (PEI) medically necessary for the treatment of hepatocellular cancers (HCC) without extra-hepatic spread. (aetna.com)
  • Klatskin's tumor (or hilar cholangiocarcinoma) is an extra-hepatic cholangiocarcinoma arising in the junction of the main right and left hepatic bile ducts. (unizg.hr)
  • This involves screening for anti-mitochondrial antibodies (AMAs), anti-nuclear antibodies (ANAs) and ruling out other conditions such as autoimmune hepatitis and primary sclerosing cholangitis (which primarily affects the extra-hepatic ducts). (euroimmun.us)
  • There is also stenosed appearance along the entire length of the extra hepatic common bile duct with few short segment stenoses as well. (smsb-llc.com)
  • The next most common injury is transection of the intrapancreatic common bile duct, followed by laceration of the left hepatic duct. (medscape.com)
  • Fortunately, the left hepatic duct was judged to be normal by imaging. (elsevierpure.com)
  • We report the case of a 27-year-old Iranian woman with congenital hepatic fibrosis leading to cirrhosis and subsequently hepatocellular carcinoma. (biomedcentral.com)
  • During preparation for transplant, a hepatic mass was discovered which was found to be hepatocellular carcinoma. (biomedcentral.com)
  • Percutaneous thermal ablation of hepatic tumors is accepted as a safe, reliable, and cost-effective therapeutic option for treating hepatocellular carcinoma and hepatic metastases. (dirjournal.org)
  • Bile duct tumors aren't all cancerous. (marijuanadoctors.com)
  • A couple examples of non-cancerous (benign) tumors are bile duct adenomas and bile duct hamartomas. (marijuanadoctors.com)
  • Since your bile duct is situated deep inside your body, doctors can't easily detect tumors during routine physical examinations. (marijuanadoctors.com)
  • [ 1 ] The classification of bile duct tumors has changed to include intrahepatic tumors of the bile ducts and extrahepatic tumors (perihilar and distal) of the bile ducts. (tri-kobe.org)
  • Tumors of the intrahepatic bile ducts originate in small intrahepatic ductules or large intrahepatic ducts that are proximal to the bifurcation of the right and left hepatic ducts. (tri-kobe.org)
  • These tumors are also known as intrahepatic cholangiocarcinomas. (tri-kobe.org)
  • Hendriquez R, Keihanian T, Goyal J, Abraham RR, Mishra R, Girotra M. Radiofrequency ablation in the management of primary hepatic and biliary tumors. (wjgnet.com)
  • In the United States, 80%-90% of primary hepatic tumors are hepatocellular carcinomas and 10%-15% are cholangiocarcinomas (CCA), both with high mortality rate, particularly CCA, which portends a worse prognosis. (wjgnet.com)
  • This review will focus on the various vascular complications related to percutaneous thermal ablation of hepatic tumors and discuss strategies to avoid and manage these complications. (dirjournal.org)
  • To approach centrally located tumors more cautiously, avoid tumors abutting large major blood vessels and biliary ducts. (dirjournal.org)
  • Several studies, trials, and meta-analyses comparing thermal ablation with surgical resection of small hepatic tumors have shown that thermal ablation is less expensive and invasive. (dirjournal.org)
  • Significant needle tract bleeding is a major complication (Common Terminology Criteria for Adverse Events grade 3 or higher) of percutaneous thermal ablation of hepatic tumors, as it can be immediately life-threatening and may lead to prolonged hospitalization. (dirjournal.org)
  • Needle tract bleeding is also the most common vascular complication related to percutaneous thermal ablation of hepatic tumors. (dirjournal.org)
  • As food moves through the digestive tract, bile is released into the small intestine, where it aids digestion and facilitates the body's absorption of fats. (moffitt.org)
  • Distal cholangiocarcinomas are found further down the bile duct, closer to the small intestine. (moffitt.org)
  • You find these closer to your small intestine, further down your bile duct. (marijuanadoctors.com)
  • When partially digested food passes from the stomach into the small intestine, the gall bladder expels bile to aid digestion. (targetwoman.com)
  • This region includes the common bile duct and inserts into the small intestine. (tri-kobe.org)
  • Endoscopic retrograde cholangiopancreatography (ERCP) showed complete obstruction of the common hepatic duct, which was caused by clipping during laparoscopic cholecystectomy. (elsevierpure.com)
  • Congenital hepatic fibrosis (CHF) is an autosomal recessive disease that primarily affects the hepatobiliary and renal systems. (medscape.com)
  • Congenital hepatic fibrosis is one of the fibropolycystic diseases, which also include Caroli disease , autosomal dominant polycystic kidney disease (ADPKD), and autosomal recessive polycystic kidney disease (ARPKD). (medscape.com)
  • Congenital hepatic fibrosis is associated with an impairment of renal functions, usually caused by an ARPKD, which is a severe form of polycystic kidney disease . (medscape.com)
  • Because of the variable clinical presentations, congenital hepatic fibrosis is believed to represent a broad spectrum of hepatic and renal lesions rather than a single clinical entity. (medscape.com)
  • Congenital hepatic fibrosis results from a malformation of the ductal plate (the embryological precursor of the biliary system), secondary biliary strictures, and periportal fibrosis. (medscape.com)
  • The classic renal lesion associated with congenital hepatic fibrosis is ARPKD, which results in an impairment of renal functions. (medscape.com)
  • The relationship of ARPKD to congenital hepatic fibrosis remains a controversial issue. (medscape.com)
  • [ 9 ] Most cases of ARPKD and congenital hepatic fibrosis are genetically homogeneous. (medscape.com)
  • However, the exact pathogenesis of association between congenital hepatic fibrosis and ADPKD still requires further research and study. (medscape.com)
  • Congenital hepatic fibrosis is an uncommon cause of portal hypertension. (biomedcentral.com)
  • Congenital hepatic fibrosis is included in the group of congenital diseases of fibropolycystic disorders. (biomedcentral.com)
  • Nakanuma Y, Harada K, Sato Y, Ikeda H. Recent progress in the etiopathogenesis of pediatric biliary disease, particularly Caroli's disease with congenital hepatic fibrosis and biliary atresia. (medscape.com)
  • Congenital dilation of the intrahepatic bile ducts. (medscape.com)
  • It is characterized by hepatic fibrosis, portal hypertension, and renal cystic disease. (medscape.com)
  • Pathologically, it is defined by its variable degree of periportal fibrosis and irregularly shaped proliferating bile ducts. (medscape.com)
  • Gradual disappearance of bile duct profiles associated with increased periportal fibrosis results from a progressive destructive cholangiopathy that involves the immature bile duct structures. (medscape.com)
  • Chapter 23 (Intrahepatic Bile Ducts) describes it as "nontumoral hepatic parenchymal fibrosis/cirrhosis. (cancer.gov)
  • Abruption can and nebraska coli asparaginase [polyethylene glycol polysorbate 80 percent for ra particularly important are reduced bile flow past week can differentiate between a systemic fibrosis. (jefflthompson.com)
  • Both interlobular and intralobular bile ductules develop from the ductal plate. (medscape.com)
  • The lack of remodeling of the ductal plate results in persistence of an excess of embryonic duct structures. (medscape.com)
  • [ 7 ] and consists of persistence of the ductal plate with an increase in duct elements and an increase in portal fibrous tissue. (medscape.com)
  • Specifically, there is beading and strictural narrowing of multiple intrahepatic bile duct branches, most pronounced at the main intrahepatic biliary ductal bifurcation. (smsb-llc.com)
  • MRCP revealing pruned appearance of the intrahepatic biliary ductal system with multifocal areas of beading and strictural narrowing which is most pronounced at the main intrahepatic biliary ductal bifurcation. (smsb-llc.com)
  • Therefore, we elected to perform a right hepatic lobectomy and left hepaticojejunostomy, because we felt that performing a hepaticojejunostomy without hepatic resection would put the patient at risk of continuing to suffer from cholangitis. (elsevierpure.com)
  • Simple resection of the lesion bile duct branch for treatment of regional hepatic bile duct stones. (bilpubgroup.com)
  • There is inadequate information to document the effectiveness of PEI as an alternative to surgical resection for the treatment of hepatic metastases. (aetna.com)
  • Improving resectability of hepatic colorectal metastases: expert consensus statement. (cancercentrum.se)
  • Cholangiography from percutaneous transhepatic biliary drainage (PTBD) catheters revealed that sections of the secondary branches of the right intrahepatic bile duct had become constricted due to persistent cholangitis. (elsevierpure.com)
  • Increased number of hepatic mitosis might be due to the stimulation from stones, hepatic biliary or secondary inflammatory. (bilpubgroup.com)
  • The secondary bile acids are further modified by bacteria in the intestine. (lookformedical.com)
  • Minimally invasive therapies like image-guided percutaneous thermal ablation have gained widespread acceptance as a method for treating focal primary and secondary hepatic malignancies. (dirjournal.org)
  • Interlobar ducts (between the main hepatic ducts and the interlobular ducts) - pseudostratified columnar epithelium. (wikipedia.org)
  • The function of bile salts in the duodenum is to solubilize ingested fat and fat-soluble vitamins, facilitating their digestion and absorption. (merckmanuals.com)
  • The bile from the gall bladder is necessary for proper digestion of fats. (targetwoman.com)
  • Cancers may occur in any area of your bile duct system. (marijuanadoctors.com)
  • You may also divide bile duct cancers into kinds determined by the appearance of cancer cells under a microscope. (marijuanadoctors.com)
  • Regardless of type, physicians refer to almost all bile duct cancers as cholangiocarcinomas. (marijuanadoctors.com)
  • This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of bile duct cancers. (tri-kobe.org)
  • Many bile duct cancers are multifocal. (tri-kobe.org)
  • The majority of cholangiocarcinomas are adenocarcinomas that develop within the mucous gland cells that line the inside of the bile duct. (moffitt.org)
  • Type IVa Choledochal Cyst: This type presents as multiple dilatations of the intrahepatic and extrahepatic biliary tree. (iswantosucandyliversurgery.com)
  • Patients with a major surgical injury to the bile duct and those with recurrent strictures and interventions may have evidence of a bile leak in the form of a biliary fistula, biliary peritonitis, or a biloma. (medscape.com)
  • We report a case requiring biliary reconstruction with right hepatic lobectomy due to biliary strictures caused by continuous cholangitis after laparoscopic bile duct injury. (elsevierpure.com)
  • Laboratory examinations revealed anaemia, elevated hepatic enzymes, elevated bilirubin profile that suggested obstructive jaundice and raised CA 19.9 levels. (eurorad.org)
  • Bile is isosmotic with plasma and consists primarily of water and electrolytes but also organic compounds: bile salts, phospholipids (mostly lecithin), cholesterol, bilirubin, and other endogenously produced or ingested compounds, such as proteins that regulate gastrointestinal function and drugs or their metabolites. (merckmanuals.com)
  • Bile salts are also biologic detergents that enable the body to excrete cholesterol and potentially toxic compounds (eg, bilirubin, drug metabolites). (merckmanuals.com)
  • Primary Biliary Cholangitis (PBC) is an autoimmune disease that affects hepatic biliary tracts (outward passageways for bile). (euroimmun.us)
  • High index of proliferation should be prevented from the potential misdiagnosis of hepatic tumor. (bilpubgroup.com)
  • Cholangiography - radiographic examination of the bile duct is performed after injecting with a special dye to check the condition of Cholangitis - infection or inflammation of the bile ducts. (targetwoman.com)
  • The prognosis of ARPKD depends on the age at presentation, along with the degree of hepatic and renal involvement. (lecturio.com)
  • In the absence of symptoms of the primary disease, most patients with bile duct strictures remain asymptomatic until the lumen of the bile duct is sufficiently narrowed to cause resistance to the flow of bile. (medscape.com)
  • The etiology of bile duct strictures is sometimes obvious at the time of presentation. (medscape.com)
  • This history provides valuable clues regarding the underlying disease and may prove useful in guiding management of patients with bile duct strictures. (medscape.com)
  • Asymptomatic patients with bile duct strictures may have unremarkable physical examination findings. (medscape.com)
  • On the other hand, cholangitis involves infection of the bile ducts either due to biliary obstruction or bacterial infection. (targetwoman.com)
  • While this is a relatively simple procedure, the possible complications include blood clots, bile leakage, injury to bile duct and infection. (targetwoman.com)
  • however, with minimal bile leakage, peritonitis may not occur initially and abdominal signs may be absent. (medscape.com)
  • Although a bile leakage from the intraabdominal drain was observed several days after the operation, the patient was not given adequate treatment to stop the leakage. (elsevierpure.com)
  • Effectiveness of hepatic parenchyma lithotomy of hepatolithiasis: a single-center experience. (bilpubgroup.com)
  • Fiberoptic endoscopy designed for duodenal observation and cannulation of VATER'S AMPULLA, in order to visualize the pancreatic and biliary duct system by retrograde injection of contrast media. (lookformedical.com)
  • Patients with Caroli disease or Caroli syndrome may have a history of intermittent abdominal pain, which reflects episodes of bile stasis or the passage of bile stones. (medscape.com)