• The hepatitis C virus (HCV), in species Hepacivirus C, infects humans and is associated with hepatitis and hepatocellular carcinoma. (wikipedia.org)
  • Hepatitis C virus (HCV), which is the causative agent of hepatitis C in humans, and a member of the species Hepacivirus C, was discovered in 1989. (wikipedia.org)
  • with previously reported NPHV se- der in the United States in 2011, ten- To phylogenetically analyze the virus quences from dogs and horses (Figure) tatively named canine hepacivirus ( 2 ), sequences based on an NS3 partial ( 2 , 6-8 ). (cdc.gov)
  • The TWiV team speaks with Amit Kapoor and Ian Lipkin about how they discovered canine hepacivirus, and its implications for the origin and evolution of hepatitis C virus. (microbe.tv)
  • Nick also demonstrated that the recently described canine hepacivirus does not appear to be associated with chronic hepatitis in dogs and has shown an association between the dog leukocyte antigen and chronic hepatitis in the ESS. (epi4dogs.com)
  • Non-primate hepacivirus (NPHV), equine pegivirus (EPgV) and Theiler's disease associated virus (TDAV) are newly discovered members of two genera in the Flaviviridae family, Hepacivirus and Pegivirus respectively, that include human hepatitis C virus (HCV) and human pegivirus (HPgV). (ox.ac.uk)
  • Proposals are described for the assignment of recently reported viruses, infecting rodents, bats and other mammalian species, to new species within the Hepacivirus and Pegivirus genera (family Flaviviridae). (ox.ac.uk)
  • The family Flaviviridae contains three genera of positive-strand RNA viruses, namely, Flavivirus, Hepacivirus (e.g., hepatitis C virus [HCV]), and Pestivirus. (uni-luebeck.de)
  • Hepacivirus is a genus of positive-strand RNA viruses in the family Flaviviridae. (wikipedia.org)
  • HCV has a positive-sense RNA genome and belongs to the genus Hepacivirus of the family Flaviviridae . (cdc.gov)
  • Among hepaciviruses, the closest known HCV relative is the equine non-primate hepacivirus (NPHV). (columbia.edu)
  • The 5' untranslated region (5'UTR) of the recently described non-primate hepacivirus (NPHV) contains a region with sequence homology to the internal ribosomal entry site (IRES) of hepatitis C virus (HCV) and GB virus B (GBV-B). Here, we demonstrated internal translation initiation by the NPHV 5'UTR in a bicistronic vector. (ox.ac.uk)
  • To name the genus comprising the hepatitis C-like viruses as the genus Hepacivirus. (wikipedia.org)
  • Viruses in the genus Hepacivirus are enveloped and have spherical icosahedral-like geometries with pseudo T=3 symmetry. (wikipedia.org)
  • Cattle are a host for viruses of the species Hepacivirus N. The viruses most closely related to Hepacivirus C are the equine hepaciviruses of the species Hepacivirus A. There are at least two subtypes of equine hepacivirus. (wikipedia.org)
  • Assignments into 14 Hepacivirus species (Hepacivirus A-N) and 11 Pegivirus species (Pegivirus A-K) are based on phylogenetic relationships and sequence distances between conserved regions extracted from complete coding sequences for members of each proposed taxon. (ox.ac.uk)
  • Viraemic frequencies and seroprevalence of non-primate hepacivirus and equine pegiviruses in horses and other mammalian species. (ox.ac.uk)
  • Lynda Coughlan joins the weekly virtual bus companions for a discussion of a host defense peptide from frogs that destroys influenza virus, and mouse models for acute and chronic hepacivirus infection. (virology.ws)
  • The presented mouse -adapted infectious clones will be of utility for reverse genetic studies, and the Norway rat hepacivirus mouse model will facilitate studies of hepacivirus infection for in-depth characterization of virus-host interactions , immune responses , and liver pathology . (bvsalud.org)
  • Every year, 3-4 million Reagent (Invitrogen, Carlsbad, CA, Until now, it has been impossible persons become infected with HCV, USA), and a target sequence in the to associate Hepacivirus infection in and 350,000 die of this infection ( 1 ). (cdc.gov)
  • Norway rat hepacivirus (NrHV) infection in rats shares HCV-defining characteristics, including hepatotropism, chronicity, immune responses , and aspects of liver pathology . (bvsalud.org)
  • Hepacivirus A infecting horses has also been found in donkeys. (wikipedia.org)
  • We propose that the species Hepatitis C virus is renamed Hepacivirus C in order to acknowledge its unique historical position and so as to minimize confusion. (ox.ac.uk)
  • We will scrutinise the reservoir dynamics of HCV by sequencing complete hepacivirus genomes from infected samples emerging from a large-scale screening of African rodents, and analyze the cross-species transmission history using novel evolutionary methods that accommodate spatial and temporal variability in selective pressures. (europa.eu)
  • Norway rat hepacivirus is of particular interest, as it enables studies in rats , an immunocompetent and widely used small laboratory animal model . (bvsalud.org)
  • Rodent hepacivirus is found in the deer mouse (Peromyscus maniculatus). (wikipedia.org)
  • Molecular Determinants of Mouse Adaptation of Rat Hepacivirus. (bvsalud.org)
  • Results of search for 'su:{Hepacivirus. (who.int)
  • with previously reported NPHV se- der in the United States in 2011, ten- To phylogenetically analyze the virus quences from dogs and horses (Figure) tatively named canine hepacivirus ( 2 ), sequences based on an NS3 partial ( 2 , 6-8 ). (cdc.gov)
  • Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Dickson Despommier, Amit Kapoor, and Ian Lipkin The TWiV team speaks with Amit Kapoor and Ian Lipkin about how they discovered canine hepacivirus, and its implications for the origin and evolution of hepatitis C virus. (virology.ws)
  • Viruses in the genus Hepacivirus are enveloped and have spherical icosahedral-like geometries with pseudo T=3 symmetry. (wikipedia.org)
  • To name the genus comprising the hepatitis C-like viruses as the genus Hepacivirus. (wikipedia.org)
  • genus Hepacivirus) represents a major public health problem, infecting about 3% of the human population. (researchgate.net)
  • Cattle are a host for viruses of the species Hepacivirus N. The viruses most closely related to Hepacivirus C are the equine hepaciviruses of the species Hepacivirus A. There are at least two subtypes of equine hepacivirus. (wikipedia.org)
  • Hepacivirus A (also known as nonprimate hepacivirus and equine hepacivirus) is a hepatotropic virus that can cause both transient and persistent infections in horses. (pacb.com)
  • Increased diversity in the HVRs was also temporally associated with seroconversion in some horses, suggesting that these regions may be targets of neutralizing antibody and may play a role in immune evasion.IMPORTANCE Hepacivirus C (hepatitis C virus) is estimated to infect 150 million people worldwide and is a leading cause of cirrhosis and hepatocellular carcinoma. (pacb.com)
  • Another unclassified virus in this taxon is duck hepacivirus-like virus. (wikipedia.org)
  • En 20.8%, se puede observar una respuesta de vacuna contra el virus de la hepatitis B. La encuesta encontrĂ³ una prevalencia del 3.2% Del reactivo anti-VHC. (bvsalud.org)
  • The evolution of intrahost viral populations (quasispecies) has not been studied in detail for hepacivirus A, and its roles in immune evasion and persistence are unknown. (pacb.com)