Hemolysis is episodic and self-limited, although rare patients have chronic, ongoing hemolysis in the absence of oxidative challenge. (merckmanuals.com)
The oxidizing agents in the plants cause oxidative hemolysis as the sulfur compound binds with the dog's RBCs. (petmoo.com)
Acute3
Exposure to naphthalene mothballs can cause acute hemolysis (anemia) in people with glucose-6-phosphate dehydrogenase deficiency. (wikipedia.org)
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked enzymatic defect common in people with African ancestry that can result in hemolysis after acute illnesses or intake of oxidant drugs (including salicylates and sulfonamides). (merckmanuals.com)
Diagnosis is based on assay for G6PD, although test results are often falsely negative during acute hemolysis due to the presence of reticulocytes, which are richer in G6PD than older cells. (merckmanuals.com)
G6PD3
The amount of hemolysis depends on the degree of G6PD deficiency and the oxidant potential of the drug. (merckmanuals.com)
Under normal circumstances, those with G6PD deficiency experience no symptoms or health issues, but with certain environmental triggers - some infectious diseases (e.g. hepatitis), some drugs (quinine, aspirin), mothballs (naphthalene) - red blood cells can become more vulnerable to damage, resulting in anaemia. (allergy-insight.com)
1-Naphthol has been used as a prooxidant to analyze its ability to induce hemolysis in a zebrafish G6PD (glucose-6-phosphate dehydrogenase) deficiency model. (sigmaaldrich.com)
Moth2
naphthalene (a chemical found in mothballs and moth crystals). (kidshealth.org)
T he key ingredient in moth balls is naphthalene, a widely-used and highly-manufactured chemical. (silentmenace.com)
Exposure4
Chronic exposure to naphthalene vapors is reported to also cause cataracts and retinal hemorrhage. (wikipedia.org)
Less commonly, hemolysis occurs after exposure to drugs or to other substances that produce peroxide and cause oxidation of hemoglobin and RBC membranes. (merckmanuals.com)
Exposure to large amounts of naphthalene may damage or destroy red blood cells. (silentmenace.com)
Exposure to large amounts of naphthalene may also cause nausea, vomiting, diarrhea and blood in the urine. (silentmenace.com)
Jaundice2
The predominant reaction is delayed intravascular hemolysis (the dissolution of red blood cells) with symptoms of anemia, fever, jaundice, and kidney or liver damage. (silentmenace.com)
Arsine causes massive hemolysis and results in anemia, jaundice, and hemoglobinuric renal failure. (cdc.gov)
Substances2
Due to the health risks of 1,4-dichlorobenzene, and flammability of naphthalene, other substances like camphor are sometimes used. (wikipedia.org)
99.75 % ) 13 2 propanol ip: 45 g / isopropanol, 1 propanol: 30 g / n propanol ethyl hexadecyl dimethyl ammonium ethylsulphate: 0.2 g emollient and moisturiser with skin protecting substances 500 ml bott with dispenser passes en 13727, en13624, en14476, en1500, en12791 standards, pack size: 500 ml bottle 14 4 methylumbelliferone ( 100gm ) ( purity ( hplc ) =98 %, mol. (jharkhandtenders.net)
Mothballs2
Older mothballs consisted primarily of naphthalene, but due to naphthalene's flammability, many modern mothball formulations instead use 1,4-dichlorobenzene. (wikipedia.org)
Mothballs containing naphthalene have been banned within the EU since 2008. (wikipedia.org)
Toxic2
Unlike naphthalene and dichlorobenzene, camphor has medicinal applications and is not regarded as a carcinogen, though it is toxic in large doses. (wikipedia.org)
The Environmental Protection Agency (EPA) has classified naphthalene as a persistent, bioaccumulative and toxic (PBT) chemical. (silentmenace.com)
Susceptible1
3] What mothers-to-be inhale, so does baby: the developing bodies of unborn children are especially susceptible to naphthalene poisoning. (silentmenace.com)
Moths1
T he very fact that naphthalene is so effective on moths as well as repelling rodents and snakes demonstrates the mere fact that it is a deadly chemical. (silentmenace.com)
Chemical1
The EPA has also classified naphthalene as a high priority PBT chemical. (silentmenace.com)