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  • proliferation
  • Hsa_Circ_0001206 is downregulated and inhibits cell proliferation, migration and invasion in prostate cancer. (nih.gov)
  • Thus, the objective of the present study is to discuss the effect of cytidine deaminase (CDA) gene silencing on the apoptosis and proliferation of CML K562 cells. (springer.com)
  • Cell proliferation, apoptosis and cell cycle were measured by CCK-8 assay and flow cytometry. (springer.com)
  • The expression of proteins relevant to cell proliferation, apoptosis and cell cycle was measured by Western blot analysis. (springer.com)
  • As a result, the proliferation of K562 cells was inhibited after CDA silencing and the cells were mainly arrested in S and G2 phases, while the apoptosis rate of these cells was increased. (springer.com)
  • Our study demonstrated that CDA gene silencing could inhibit CML cell proliferation and induce cell apoptosis. (springer.com)
  • Therefore, in this study, we aimed to investigate the effects of CDA gene silencing of the apoptosis and proliferation of CML K562 cells. (springer.com)
  • malignant
  • 8 ] At present, t-MN account for 10-20% of all malignant myeloid diseases. (mjhid.org)
  • CTL019 is an investigational therapy whereby autologous T cells are genetically engineered with a chimeric antigen receptor (CAR) to identify and eliminate CD19-expressing malignant B cells. (medworm.com)
  • apoptosis
  • Up-regulation of long intergenic noncoding RNA 01296 in ovarian cancer impacts invasion, apoptosis and cell cycle distribution via regulating EMT. (nih.gov)
  • tyrosine
  • The introduction of tyrosine kinase inhibitors (TKI) has dramatically improved the prognosis of chronic myeloid leukaemia (CML) patients and, therefore, changed the therapeutic scenario of this disease. (emjreviews.com)
  • Background Osimertinib is an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that is selective for both EGFR-TKI sensitizing and T790M resistance mutations in patients with non-small-cell lung cancer. (cancerindex.org)