Hematopoietic stem cell transplantation autologous bone marrow transplant bone marrow transplantation. Medical search. Frequent questions

High-dose chemotherapy and bone marrow transplant (HDC/BMT), also high-dose chemotherapy with autologous bone marrow transplant (HDC/ABMT or just ABMT), was an ineffective treatment regimen for metastatic breast cancer, and later high-risk breast cancer, that was considered promising during the 1980s and 1990s. (wikipedia.org)
With an overall idea that more is better, this process involved taking cells from the person's bone marrow to store in a lab, then to give such high doses of chemotherapy drugs that the remaining bone marrow was destroyed, and then to inject the cells taken earlier back into the body as replacement. (wikipedia.org)
3 The idea for high-dose chemotherapy (HDC) with autologous bone marrow transplant (ABMT) originated in the 1950s as a leukemia treatment, when E. Donnall Thomas had shown that bone marrow could be harvested from a person and transplanted into the same or another person. (wikipedia.org)
The treatment of high-dose chemotherapy with autologous bone marrow transplant had serious, lasting, and sometimes deadly side effects for the patient, including cardiac toxicity, sepsis, pulmonary failure, and nephrotoxicity, among others. (wikipedia.org)
Once Thomas is done with Chemotherapy, the cells will be given inside Thoma's bloodstream. (gomedii.com)
In a stem cell transplant, the patient gets high-dose of chemotherapy. (gomedii.com)
Chemotherapy, either at conventional levels or in the higher-dosed myeloablative protocols used in conditioning regimens (with or without total body radiation in preparation for hematopoietic cell transplantation [HCT]), often results in erythema, edema, atrophy, and ulceration of the oral mucosa, a condition generally referred to as oral mucositis. (medscape.com)
Stem cell transplantation is performed after high-dose chemotherapy (HDC) to restore a cancer patient's blood and immune cell production capacity. (bdbiosciences.com)
3 Following exogenous stimulation, such as chemotherapy or using growth factors such as granulocyte colony stimulating factor (G-CSF) and filgrastim, the number of HSCs in the peripheral blood increases, either becoming on par or even exceeding the number in the bone marrow. (bdbiosciences.com)
For many hematopoietic malignancies, collection and infusion of CD34+ hematopoietic stem/progenitor cells following chemotherapy is critical. (bdbiosciences.com)
Before chemotherapy medicines suppress the immune system, hematopoietic stem cells-which produce blood cells-that are generated from a person's bone marrow or blood are collected or kept. (bonemarrowtransplantations.com)
Autologous HSCT following high-dose chemotherapy, the standard treatment for adult patients with relapsed HL, is also effective in paediatric patients, but randomized trials showing its superiority to conventional therapy are lacking. (nih.gov)
Autologous hematopoietic stem cell transplantation, or aHSCT for short, is usually used to treat blood cancers, and involves harvesting stem cells from the person's own bone marrow or blood followed by chemotherapy and antibody treatment. (news-medical.net)
Angiocrine Bioscience Inc. will use genetically engineered cells, derived from cord blood, to see if they can help alleviate or accelerate recovery from the toxic side effects of chemotherapy for people undergoing treatment for lymphoma and other aggressive cancers of the blood or lymph system. (ca.gov)
Viral infection can lead to fatal complications in patients with weakened immune systems resulting from chemotherapy, bone marrow or cord blood transplant, and other forms of inherited or acquired disorders. (ca.gov)
Angiocrine is developing a cell therapy aimed to improve the availability and engraftment of blood stem cell transplants for cancer patients who have had their cancerous bone marrow removed by chemotherapy. (ca.gov)
Hematopoietic stem cell transplantation is also sometimes used for solid tumors (eg, some germ cell tumors) that respond to chemotherapy. (msdmanuals.com)
We extract blood cells, treat the cancer with high-dose chemotherapy , then place the cells back into the patient. (mdanderson.org)
Once the cancer is less active and the patient has been pre-treated with chemotherapy (known as conditioning), he or she receives the donor's healthy stem cells. (mdanderson.org)
The study reviewed the duration and dosing of participants' induction regimens, the date of final chemotherapy, and any biochemical response achieved before transplantation. (bloodcancerstoday.com)
They then injected the patients with their own immune stem cells, obtained from the patients' blood before the chemotherapy, to create a new immune system. (scienceblog.com)
We focus on destroying only the immune component of the bone marrow and then regenerate the immune component, which makes the procedure much safer and less toxic than traditional chemotherapy for cancer," Burt said. (scienceblog.com)
Opportunistic infections (OIs) are defined as any in- the infusion of hematopoietic stem cells from a donor fections that occur with increased frequency or severity into a patient who has received chemotherapy, which in HSCT patients. (cdc.gov)
We report a patient with PNP deficiency, who received HLA-identical sibling marrow without chemotherapy because of disseminated cytomegalovirus (CMV) infection. (frontiersin.org)
In view of the disseminated CMV infection, the decision was made to infuse stem cells without any pre-conditioning chemotherapy. (frontiersin.org)
Once destroyed, the immune system is then rebuilt using blood and bone marrow stem cells which would have been collected from the patient's own blood prior to chemotherapy. (sheffield.ac.uk)
[ 2 ] Options for second-line therapy in patients with relapsed/refractory disease include chemotherapy-free regimens with biologic targeted agents such as covalent Bruton tyrosine kinase (BTK) inhibitors, lenalidomide,venetoclax, and chimeric antigen receptor (CAR) T-cell therapy. (medscape.com)

In such cases, there are cells from your own body and hence have certain advantages over stem cells from a donor. (gomedii.com)
Allogeneic stem cell transplant uses healthy blood stem cells from a donor to replace bone marrow that's not producing enough healthy blood cells. (gomedii.com)
Based on the report Thomas will either go through Allogenic (related Donor) or Autologous (healthy cells from their own body) donor selection. (gomedii.com)
During the additional follow-up reported here, CD4 T-cell reconstitution has reached normal values in peripheral blood with 100% donor chimerism as confirmed by absent CCR5 expression. (ashpublications.org)
Overview and choice of donor of hematopoietic stem cell transplantation. (mayoclinic.org)
National Marrow Donor Program. (mayoclinic.org)
The bone marrow transplant procedure is highly safe for the donor and is used to treat various conditions, both cancerous and non-cancerous. (bonemarrowtransplantations.com)
This procedure takes stem cells from a closed match donor or a family member. (bonemarrowtransplantations.com)
Identification by random forest method of HLA class I amino acid substitutions associated with lower survival at day 100 in unrelated donor hematopoietic cell transplantation. (uchicago.edu)
T-cell-depleted allogeneic transplant without donor leukocyte infusions results in excellent long-term survival in patients with multiply relapsed Lymphoma. (uchicago.edu)
Various factors including age, sex, performance status (PS), disease status, cytogenetic risk, donor type, graft source, sex mismatch between the donor and the recipient, and year of transplantation were all shown to impact OS 2 . (apbmt.org)
Therapeutic Candidate or Device OSSM007: cryopreserved, interferon-gamma-primed bone marrow mesenchymal stem cells (BM-MSC) Indication acute Graft versus host disease (aGVHD) resulting from hematopoietic cell transplantation Therapeutic Mechanism Immunomodulation of host-reactive T cells to induce operational tolerance of donor HSC-derived lymphocytes through direct cell-to-cell contact and secreted paracrine factors. (ca.gov)
eg, bone, bone marrow, and skin grafts) Genetically identical (syngeneic [between monozygotic twins]) donor tissue (isografts) Genetically. (msdmanuals.com)
Hematopoietic stem cell transplantation may be autologous (using the patient's own cells) or allogeneic (using cells from a donor). (msdmanuals.com)
Where do allogeneic stem cell transplant donor cells come from? (mdanderson.org)
With a bone marrow transplant, the donor receives general anesthesia , and the bone marrow is extracted in a 1-2-hour procedure. (mdanderson.org)
With a peripheral blood cell transplant, the donor receives growth factor shots to stimulate the bone marrow to push the stem cells into the blood. (mdanderson.org)
This allows us to collect more cells in a short period, decrease patient/donor downtime and freeze the cells for future use. (mdanderson.org)
For many patients who don't have a well-matched, healthy donor, a cord blood transplant is a viable option. (mdanderson.org)
Many patients find matched unrelated donors through the National Marrow Donor Program. (mdanderson.org)
If the donor cells aren't a close enough match, the patient's body may recognize the donor cells as foreign and reject them. (mdanderson.org)
Or, the cells from the donor may recognize the new body as foreign and attack. (mdanderson.org)
Cells for HSCT may be obtained from the patient himself or herself (autologous transplant) or from another person, such as a sibling or unrelated donor (allogeneic transplant) or an identical twin (syngeneic transplant). (yashfiin.com)
A Japanese man who had been diagnosed with aplastic anemia underwent allogenic bone marrow transplantation from an unrelated donor at 51 years of age. (biomedcentral.com)
However, HLA-identical sibling stem cell infusions in ADA-SCID result in some donor stem cell engraftment and long-term thymopoiesis. (frontiersin.org)
She received a matched sibling donor unconditioned stem cell infusion at 16 months of age. (frontiersin.org)
There was 93% donor T-lymphocytes, 20% donor B-lymphocytes, and 5% donor myeloid cells, indicative of some donor stem cell engraftment. (frontiersin.org)
Other treatments are allogeneic, meaning the stem cells are from a donor. (mssociety.ca)
Seven patients were transplanted using a matched sibling donor upfront, and one patient was treated with CSA and growth factors only. (springermedizin.at)

For this research, Prof. Inglese and her staff examined the information of 79 individuals with lively secondary progressive MS who acquired autologous hematopoietic stem cell transplants (AHSCT). (getnom.net)
In research presented in Bone Marrow Transplantation , investigators examined whether the time interval from ending induction therapy to receiving an autologous hematopoietic stem cell transplant (AHSCT) impacted outcomes in patients with multiple myeloma (MM). Lead author, Charalampos Charalampous, MD, noted that the last cycle of induction therapy is typically completed two to four weeks before transplantation. (bloodcancerstoday.com)
Analysis reveals that for greater than 20 years, autologous hematopoietic stem cell transplant, or aHSCT, has been an efficient therapy for these with extremely lively relapsing-remitting MS that doesn't reply nicely to medicines. (healthgienic.com)
It will be the first to compare how effectively autologous hematopoietic stem cell transplantation (AHSCT) is when compared with four other highly effective drug treatments which have shown great promise in clinical trials (alemtuzumab, ocrelizumab, ofatumumab and cladribine). (sheffield.ac.uk)

In the animal studies, the disease activity index dramatically decreased in the mesenchymal stem cell (MSC) treatment groups compared to the control group. (biomedcentral.com)
Mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs) have been shown to counter rheumatoid arthritis, autoimmune hepatitis, and systemic sclerosis [ 8 ]. (biomedcentral.com)
A Systematic Review and Meta-analysis of Mesenchymal Stem Cell Injections for the Treatment of Perianal Crohn's Disease: Progress Made and Future Directions. (wizaxe-prod.com)
In this post, I will explain mesenchymal stem cells and the MESCAMS study in particular, in the hopes of clarifying any misconceptions surrounding this promising therapy. (mssociety.ca)
What are mesenchymal stem cells? (mssociety.ca)
The more specialized adult stem cells (a category to which mesenchymal stem cells belong), on the other hand, are more limited in the types of cells they can differentiate into, and are generally involved in repairing damaged tissues or replacing aging cells. (mssociety.ca)
Mesenchymal stem cells are a type of adult stem cell found predominantly in the bone marrow, but have also been reported to reside in muscle, fat, and umbilical cord blood. (mssociety.ca)
Although mesenchymal stem cells have traditionally been investigated by researchers for their regenerative potential for bone and cartilage injuries, they also hold promise for people living with MS due to their capacity to suppress inflammation and assist in the repair of damaged nervous tissue. (mssociety.ca)
Studies exploring the therapeutic benefits of mesenchymal stem cell therapies for MS are in their infancy, but the results to date have been so encouraging so as to warrant a concerted, international effort in the scientific community to accelerate research into testing the safety and feasibility of this therapy in people living with MS. (mssociety.ca)
Take a look at our MS Society Fact Sheet for more information about mesenchymal stem cells. (mssociety.ca)
MESCAMS is a randomized, double-blind, cross-over, phase II clinical trial (that's quite a mouthful, but I'll explain what that means in a moment) investigating the safety and therapeutic potential of mesenchymal stem cell therapy for people with MS. The study will involve40 patients who will receive the treatment one at two sites - The Ottawa Hospital and Health Sciences Centre (HSC) Winnipeg . (mssociety.ca)
It comprises of two types of stem cells, that are hematopoietic and mesenchymal stem cells. (powershow.com)
Mesenchymal stem cells (MSCs) are ASCs, and were first described in 1966 by Friedenstein et al. (bvsalud.org)

3 , 4 In addition, T-cell reconstitution can be achieved in HIV+ patients after SCT, as was recently shown in a series of autologous SCT in HIV patients with relapsed lymphoma. (ashpublications.org)
HDC with transplant is now standard therapy in multiple myeloma, acute myeloid leukemia in first remission, and intermediate-grade non-Hodgkin's lymphoma. (bdbiosciences.com)
Data suggest that young patients with recurring disease following autologous HSCT, as well as some patients with multiple relapses and selected patients with refractory lymphoma, might benefit from allogeneic HSCT, but relapse remains the major challenge. (nih.gov)
Second autologous stem cell transplantation for relapsed lymphoma after a prior autologous transplant. (uchicago.edu)
As well as, HSCT is a therapy choice for sure blood-related illnesses, together with lymphoma , leukemia , and sickle cell illness . (getnom.net)
A randomized phase III trial of consolidation with autologous hematopoietic cell transplantation followed by maintenance rituximab vs. maintenance rituximab alone for patients with mantle cell lymphoma in minimal residual disease-negative first complete remission. (slu.edu)
Adult T-cell leukemia/lymphoma (ATLL) is a rare and aggressive disease caused by human T-cell lymphotropic virus type 1 that predominantly affects Japanese and Caribbean populations. (oncotarget.com)
Adult T-cell leukemia/lymphoma (ATLL) is a rare mature T-cell malignancy first described in Japan in 1977 [ 1 ]. (oncotarget.com)
A stem cell transplant is often the best option to treat blood cancers, such as leukemia , lymphoma and multiple myeloma , as well as bone marrow failure syndromes like myelodysplastic syndrome . (mdanderson.org)
Mantle cell lymphoma (MCL) is a lymphoproliferative disorder derived from a subset of naive pregerminal center cells localized in primary follicles or in the mantle region of secondary follicles. (medscape.com)
Mantle cell lymphoma (MCL) is recognized in the Revised European-American Lymphoma and World Health Organization classifications as a distinct clinicopathologic entity. (medscape.com)
it was frequently categorized as diffuse small-cleaved cell lymphoma (by the International Working Formulation) or centrocytic lymphoma (by the Kiel classification). (medscape.com)

If your child received bone marrow from someone else, look for signs of graft-versus-host disease ( GVHD ). (medlineplus.gov)
Autologous graft-versus-host disease: harnessing anti-tumor immunity through impaired self-tolerance. (uchicago.edu)
After transplantation, he suffered acute graft-versus-host disease with a systemic rash and severe diarrhea. (biomedcentral.com)

These data suggest that with appropriate pre-transplant clinical evaluation, high-dose cyclophosphamide and irradiation in the BMT preparative phase does not result in frequent, clinically relevant short-term cardiac toxicity [31]. (slideshare.net)
Treatment of therapy-related myeloid neoplasms with high-dose cytarabine/mitoxantrone followed by hematopoietic stem cell transplant. (uchicago.edu)
Clinicopathologic features of late-onset veno-occlusive disease/sinusoidal obstruction syndrome after high dose intravenous busulfan and hematopoietic cell transplant. (uchicago.edu)

Mayo Clinic scientists are actively studying ways to improve bone marrow transplant outcomes. (mayoclinic.org)
Results of Bone marrow transplant in Max hospital are very successful, as the surgeons pay close attention to even the smallest details and choose the best course of care, resulting in the best outcomes. (bonemarrowtransplantations.com)
Outcomes of patients with AML and MDS who relapse or progress after reduced intensity allogeneic hematopoietic cell transplantation. (uchicago.edu)
Pretreatment C-reactive protein is a predictor for outcomes after reduced-intensity allogeneic hematopoietic cell transplantation. (uchicago.edu)
We analyzed the epidemiology and outcomes of treatment of invasive fungal disease (IFD) in children during anticancer therapy (PHO, pediatric hematology and oncology) or after hematopoietic cell transplantation (HCT) over a period of eight consecutive years in a single-center study. (viamedica.pl)
Based on a retrospective analysis of patients with newly diagnosed MM, Dr. Charalampous and colleagues concluded that a prolonged time to transplant (TTT) was associated with worse outcomes compared with a more rapid schedule. (bloodcancerstoday.com)
Allogenic hematopoietic stem cell transplantation recipients often develop several opportunistic infections associated with fatal outcomes. (biomedcentral.com)
Earlier work from MSK physician-scientists Eric Pamer, MD, and Marcel van den Brink, MD, PhD , has shown that out-of-balance intestinal microbes can contribute to serious side effects that can affect outcomes after stem cell transplants. (mskcc.org)
Autologous Haematopoietic Stem Cell Transplantation for Crohn's Disease: A Retrospective Survey of Long-term Outcomes from the European Society for Blood and Marrow Transplantation. (wizaxe-prod.com)
Objective: The Center for International Bone Marrow Transplant Research (CIBMTR) submitted a study concept comparing the outcomes of patients aged 55 to 64 years vs aged 65 years or older who met those criteria, effectively providing coverage by CMS for HCT for MDS. (wustl.edu)
Though Molson had life-changing outcomes from the stem cell transplant, the therapy just isn't a one-size-fits-all method for everybody dwelling with MS . Thereare nonetheless plenty of unanswered questions, Cohen says. (healthgienic.com)
Outcomes of corneal transplantation in Europe: report by the European Cornea and Cell Transplantation Registry. (who.int)

By demonstrating compliance with the FACT-JACIE International Standards for Cellular Therapy Product Collection, Processing and Administration , the joint program of Fox Chase Cancer Center and Temple has earned FACT reaccreditation for adult allogeneic and autologous hematopoietic progenitor cell transplantation, peripheral blood cellular therapy product collection, and cellular therapy product processing with minimal manipulation. (foxchase.org)

Colette Beecher, 50, from Wickersley, Rotherham, was diagnosed with MS in January 2011, and has been relapse-free for three years after having the MS stem cell transplantation at Sheffield's Royal Hallamshire Hospital in April 2016. (sheffield.ac.uk)

Peripheral blood stem cell and bone marrow transplantation for solid tumors and lymphomas: hematologic recovery and costs. (nature.com)

1 , 2 The patient has since remained off antiretroviral therapy (ART) and without evidence of HIV disease for 45 months after the SCT despite relapse of his AML, which necessitated a second successful transplantation. (ashpublications.org)
12 months after completion of therapy) may be cured with conventional therapy, those with progressive disease or early relapse (3-12 months) are considered candidates for autologous HSCT. (nih.gov)
Short time to relapse and refractory disease at the time of autologous HSCT remain the most important risk factors. (nih.gov)
Predictors for survival after transplant relapse. (uchicago.edu)
National Cancer Institute's First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: summary and recommendations from the organizing committee. (uchicago.edu)
Allogeneic HCT has been widely used, while autologous HCT, which is still useful, is less prevalent because of concerns around post-transplant relapse, as well as the recently extended application of allogeneic HCT. (apbmt.org)
LICs give rise to drug-resistance and relapse and remain unsolved clinical problems in B cell tumors. (ca.gov)
Therapeutic Candidate or Device TriLeukeVax, an autologous AML vaccine designed to stimulate induction of anti-leukemic cytolytic activity and improve relapse free survival (RFS). (ca.gov)

30,000 patients with blood-related malignancies receive HDC, which, if the response is satisfactory, could subsequently be followed by hematopoietic stem cell transplantation (HSCT). (bdbiosciences.com)
this is used in both autologous and allogenic HSCT. (bdbiosciences.com)
Hematopoietic stem cell transplantation (HSCT) affects serious risks for the patient, including death. (bvsalud.org)
HSCT) has significantly modified the prognosis of when the pathological process involves BM or when patients with hereditary or acquired hematological, hematopoietic toxicity is the limiting factor in the oncological and immunological diseases and it is the aggressive treatment of the disease. (bvsalud.org)
HSCT make it an aggressive process, causing consists of painless intravenous infusion of healthy toxicity and can generate significant complications hematopoietic stem cells (HSC) extracted from bone and several side effects adding feelings of worry, marrow (BM), peripheral blood (PB) and placental anguish, anxiety, among others (KUBA et al. (bvsalud.org)
Also, drastic changes in daily living habits, qualified and responsible for the implementation of changes in body image, long duration of treatment, HSCT since 2004, agreed to the Brazilian Unified periods of hospitalization and protective isolation, Health System, which meets the needs of the feeling of loss of control, fear of death and lack of patients with an indication for transplantation. (bvsalud.org)
Salvage therapy options include further chemo-radiotherapy and autologous or allogeneic haematopoietic SCT (HSCT). (nih.gov)
According to patient selection criteria, overall and disease-free survival rates after autologous HSCT are 43-95% and 31-70%, respectively. (nih.gov)
Hematopoietic stem cell transplantation (HSCT) is a therapy utilizing wholesome blood or bone marrow stem cells. (getnom.net)
HSCT is at the moment used to deal with male germ cell tumors , also called testicular tumors. (getnom.net)
Hematopoietic stem cell transplantation (HSCT) involves the intravenous infusion of hematopoietic stem cells in order to reestablish blood cell production in patients whose bone marrow or immune system is damaged or defective. (yashfiin.com)
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the optimal treatment for pediatric patients with high-risk or intermediate-acute myeloid leukemia. (blood-genomics.com)
There was no difference in transplantation-related toxicity (TRT) in terms of infection, hepatic dysfunction, oral mucositis, and engraftment syndrome between the haploidentical HSCT and HLA-matched HSCT groups. (blood-genomics.com)
For the purposes of this document, HSCT is defined of the CDC, the Infectious Diseases Society of America, as any transplantation of blood or marrow-derived he- and the American Society of Blood and Marrow Trans- matopoietic stem cells, regardless of transplant type plantation," which was published in the Morbidity and (allogeneic or autologous) or cell source (bone marrow, Mortality Weekly Report [1]. (cdc.gov)
There pediatric and adult autologous and allogeneic HSCT patients. (cdc.gov)
are basically 3 phases of immune recovery for HSCT patients, The purposes of the guidelines are (1) to summarize the beginning at day 0, the day of transplantation. (cdc.gov)

The CD4 T cells of the patient, similarly to other SCT recipients, had a higher proportion of activated effector memory cells and a lower proportion of naive cells compared with healthy controls. (ashpublications.org)
CD4 T-cell reconstitution was also achieved in the gut mucosa in the reported patient, again to a similar degree as that observed in other SCT recipients. (ashpublications.org)
BK virus infection is associated with hematuria and renal impairment in recipients of allogeneic hematopoetic stem cell transplants. (uchicago.edu)
Pilot study of comprehensive geriatric assessment (CGA) in allogeneic transplant: CGA captures a high prevalence of vulnerabilities in older transplant recipients. (uchicago.edu)
Recipients of allogeneic transplantation had significantly improved overall survival compared to non-transplanted patients. (oncotarget.com)
Hopefully, following the recommendations made in the guidelines will reduce morbidity and mortality from opportunistic infections in hematopoietic stem cell transplant recipients. (cdc.gov)
In May 2010, the Sixty-third World Health Assembly adopted resolution WHA63.22,1 in which it endorsed the updated WHO Guiding Principles on Human Cell, Tissue and Organ Transplantation and provided strategic directions to support progress in human organ, tissue and cell donation with the aim of maximizing the benefits of transplantation, meeting the needs of recipients, protecting donors and ensuring the dignity of all involved. (who.int)
Corneal disease (scarring or perforation) can be successfully addressed through transplantation in 80% of affected individuals.3 Tissue transplantation allows many recipients to return to economically productive lives and promotes their independence. (who.int)

Now, stem cells are more often collected from blood (a peripheral blood stem cell transplant). (gomedii.com)
While quadruplet induction therapies deepen responses in newly diagnosed multiple myeloma patients, their impact on peripheral blood stem cell (PBSC) collection remains incompletely understood. (biomedcentral.com)
Nonrelapse-related mortality was increased after carmustine (RR = 2.3) and with use of peripheral blood stem cells (RR = 2.4). (qxmd.com)
The number of related HCTs has remained stable, while the use of peripheral blood stem cells (PBSCs) has now largely replaced that of bone marrow (BM). (apbmt.org)
In order to assess the incidence and analyze reasons which cause prolongation of hospital stay in patients engrafted after peripheral blood stem cell transplantation (PBSCT), we performed this retrospective analysis. (nature.com)

An autologous stem cell transplant uses the patient's own cells for treatment. (mdanderson.org)

Histopathologic criterion: Evidence of macrophage hemophagocytosis is found in the bone marrow aspirate sample. (medscape.com)

1,000 new AML patients undergoing allogeneic or autologous HCT. (apbmt.org)
This article contains highlights of "Guidelines for Pre- allogeneic or autologous, depending on the source of venting Opportunistic Infections among Hematopoi- the transplanted hematopoietic progenitor cells. (cdc.gov)

An autologous stem cell transplant is the process where healthy blood stem cells from your own body are used to replace your damaged bone marrow. (gomedii.com)
Now a staff of researchers from the College of Genoa in Italy discovered hematopoietic stem cell transplants utilizing an individual's wholesome blood stem cells assist delay incapacity longer in individuals with lively secondary progressive MS than some MS drugs. (getnom.net)
Research Objective Our research will determine how aging of human blood stem cells leads to dramatic increases in disorders of platelets, cells that normally prevent bleeding but form harmful clots when dysregulated. (ca.gov)
Therapeutic Candidate or Device Autologous blood stem cells edited to restore iduronidase expression Indication Severe Mucopolysaccharidosis Type 1 (MPS1/ Hurler's syndrome) Therapeutic Mechanism Autologous blood stem cells undergo genome editing to restore the production of the missing enzyme. (ca.gov)
[5] Conditions such as anemias and immunodeficiencies, for which fetal tissue attempts largely failed, are now treated routinely with adult stem cells, including umbilical cord blood stem cells, [6] even while the patient is still in the womb. (lozierinstitute.org)

In June 2018, the Secretariat established the WHO Task Force on Donation and Transplantation of Human Organs and Tissues as an advisory group composed of experts from all WHO regions. (who.int)

99% of transplantation centers in Japan. (apbmt.org)
The Japanese Society of Hematopoietic Cell Transplantation (JSHCT) has been conducting a nationwide survey on HCT since 1993, in which HCTs performed at participating centers are registered with the JSHCT every year. (apbmt.org)
300 transplantation centers nationwide, with a penetration rate exceeding 99% 1 . (apbmt.org)
Importance: In 2010, the US Centers for Medicare & Medicaid Services (CMS) indicated that data regarding efficacy of allogeneic hematopoietic stem cell transplantation (HCT) in the CMS beneficiary population with myelodysplastic syndrome (MDS) were currently insufficient, but that coverage would be provided for patients enrolled in a clinical study that met its criteria for Coverage with Evidence Development (CED). (wustl.edu)
It comprises a voluntary working group of more than 420 centers worldwide that contribute detailed data on allogeneic and autologous HCT and cellular therapies. (wustl.edu)
Since 2007, FACT accreditation has been used in determining the U.S. News & World report rankings of transplant centers for the "America's Best Hospitals" and "America's Best Children's Hospitals" list. (foxchase.org)

The cancer cells use that protein to evade the component of our immune system that routinely destroys tumors. (ca.gov)
Research Objective LGR5-antibody drug conjugate to target LIC in B cell tumors that undergo self-renewal Impact LIC were only defined in myeloid leukemia, while LIC populations in B cell tumors remain elusive. (ca.gov)

Bone Marrow Transplant is the procedure to replace bone marrow stem cells with a matched, healthier bone marrow stem cell. (bonemarrowtransplantations.com)

A total of 179 transplant-eligible patients with newly diagnosed MM treated at a single academic center were included. (biomedcentral.com)
Impact of the time interval between end of induction and autologous hematopoietic transplantation in newly diagnosed patients with multiple myeloma. (bloodcancerstoday.com)

Identifying familial myelodysplastic/acute leukemia predisposition syndromes through hematopoietic stem cell transplantation donors with thrombocytopenia. (uchicago.edu)
Allogeneic hematopoietic stem cell transplantation is limited mainly by lack of histocompatible donors. (msdmanuals.com)

Hematopoietic Stem Cell Transplantation in Refractory Crohn's Disease: Should It Be Considered? (mdpi.com)
Feasibility of clofarabine cytoreduction before allogeneic transplant conditioning for refractory AML. (uchicago.edu)
Phase II study of immunomodulation with granulocyte-macrophage colony-stimulating factor, interleukin-2, and rituximab following autologous stem cell transplant in patients with relapsed or refractory lymphomas. (uchicago.edu)
Research Objective We will use integrated gene editing techniques to develop a new CAR-T cell therapy for multiple myeloma treatment Impact Develop an improved CAR-T cell therapy for patients with refractory multiple myeloma and a new manufacturing strategy that circumvents the costs and inefficiencies of viral production. (ca.gov)
Allogeneic transplantation was performed in five patients, two of whom achieved complete remission despite residual or refractory disease. (oncotarget.com)
Autologous stem cell transplantation in refractory Crohn's disease - low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study. (wizaxe-prod.com)
A Review on Behalf of the EBMT Autoimmune Diseases Working Party and the Autologous Stem Cell Transplantation In Refractory CD-Low Intensity Therapy Evaluation Study Investigators. (wizaxe-prod.com)
Autologous stem-cell transplantation in treatment-refractory Crohn's disease: an analysis of pooled data from the ASTIC trial. (wizaxe-prod.com)
Hematopoietic stem cell transplantation in a severe refractory Crohn's disease patient with intestinal stoma: a case report. (wizaxe-prod.com)
Autologous hematopoietic stem cells for refractory Crohn's disease. (wizaxe-prod.com)
Resetting of the Mucosal T Cell Repertoire after Hematopoietic Stem Cell Transplantation in Refractory Crohn's Disease. (wizaxe-prod.com)
Stem Cell Transplantation for Refractory Crohn Disease. (wizaxe-prod.com)
Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial. (wizaxe-prod.com)

with genotype T18 in an immunodeficient patient in Japan after allogenic bone marrow transplantation, along with the morphological characteristics and genetic analysis. (biomedcentral.com)
A 52-year old man, who had undergone allogenic bone marrow transplantation, suffered from rapid-growing brain masses in addition to pneumonia and died within 1 month from the onset of the symptoms including fever, headache and disorientation. (biomedcentral.com)
with genotype T18 after allogenic bone marrow transplantation with review of the literature. (biomedcentral.com)

Chemotherapeutic regimens have previously been used in HIV+ patients to treat malignancies, but did the preparative and conditioning regimens in this case, which included total body irradiation and antithymocyte globulin, contribute to the possible elimination of resistant reservoirs such as resting CD4 T cells and macrophages? (ashpublications.org)
Fludarabine and melphalan-based conditioning for patients with advanced hematological malignancies relapsing after a previous hematopoietic stem cell transplant. (uchicago.edu)
We assessed late mortality in 854 individuals who had survived 2 or more years after autologous hematopoietic cell transplantation (HCT) for hematologic malignancies. (qxmd.com)

By using an autologous bone marrow transplant, the immune system is attempted to be reset. (bonemarrowtransplantations.com)
The transplanted cells kill any remaining cancer cells and restore the patient's immune system. (mdanderson.org)
After the transplantation, the patient's new lymphocytes or immune cells are self-tolerant and do not attack the immune system. (scienceblog.com)

Their objective is to research the efficacy of autologous transplantation of hematopoietic stem cells in opposition to the most effective accessible high-efficacy therapy in sufferers with very lively relapsing-remitting MS. (getnom.net)

Stem cells harvested from a person's own bone marrow or blood, can safely slow progression of the most common form of the autoimmune disease, multiple sclerosis, or MS as it's usually known, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry. (news-medical.net)
Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases: updated guidelines and recommendations from the EBMT Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of EBMT and ISCT (JACIE). (nih.gov)
Researchers from Northwestern University's Feinberg School of Medicine appear to have reversed the neurological dysfunction of early-stage multiple sclerosis patients by transplanting their own immune stem cells into their bodies and thereby "resetting" their immune systems. (scienceblog.com)
A world-first trial is investigating if stem cell transplantation could be used in patients with aggressive multiple sclerosis (MS) as a first-line treatment. (sheffield.ac.uk)

Autologous and allogeneic bone marrow transplant procedures are most frequently used to treat blood disorders or cancers. (bonemarrowtransplantations.com)
Melinda is highly proficient in the use of in vitro and in vivo assays for normal and malignant hematopoietic stem and progenitor cells, determination of self-renewal, expansion and lineage specific differentiation capabilities, and the use of induced pluripotent stem cells for the investigation of hematopoietic disorders and leukemic progression and the testing of targeted therapeutics. (edu.au)
Haematopoietic stem cell transplants have been performed in more than 1 500 000 patients (both autologous and allogeneic) to date.1 Although haematological cancers remain the main indication, haematopoietic stem cell transplants are increasingly considered in the treatment of non-malignant disorders and genetic diseases such as haemoglobinopathies (sickle cell anaemia, thalassaemia) that can benefit greatly from this type of transplant. (who.int)
Impact of Genetic Diagnosis on the Outcome of Hematopoietic Stem Cell Transplant in Primary Immunodeficiency Disorders. (cdc.gov)

As a centre of excellence in Hematopoietic Stem Cell Transplantation, ADSCC will provide an integrated and specialised range of surgical and non-surgical clinical services with world-class healthcare quality for patients who require hematopoietic stem cell transplantation for the treatment of blood diseases that includes autologous stem-cell transplantation, and allogeneic stem-cell transplantation and CAR-T cell therapy. (hospitalsmagazine.com)
This study demonstrates that stem cell collection is feasible after prolonged induction with isatuximab-RVd without collection failures and might be further explored as induction therapy. (biomedcentral.com)
PBSC mobilization should be performed after induction therapy to ensure collection of a sufficient number of cells. (biomedcentral.com)
Allogeneic blood cell transplantation following reduced-intensity conditioning is effective therapy for older patients with myelofibrosis with myeloid metaplasia. (uchicago.edu)
European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of the International Society for Cellular Therapy (ISCT) and EBMT (JACIE). (nih.gov)
For that reason, docs and scientists are taking a look at utilizing stem cells as a therapy choice for illnesses . (getnom.net)
After 10 years of therapy, scientists discovered individuals who acquired stem cell transplants decreased their rating by a median of 0.01 factors per 12 months, exhibiting a lower in incapacity. (getnom.net)
We explored whether stem cell therapy was effective for animal models and patients with Crohn's disease (CD). (biomedcentral.com)
Stem cell transplantation is a valuable supplementary therapy for CD. (biomedcentral.com)
Several studies have evaluated the safety and effectiveness of CD stem cell therapy, but the results remain controversial. (biomedcentral.com)
Many cancers resist current therapies due to therapy-resistant cancer stem cells (CSCs). (ca.gov)
This is the first analysis to describe ATLL pathological features, cytogenetics, and response to standard therapy and transplantation in the Caribbean cohort. (oncotarget.com)
The only curative therapy is hematopoietic stem cell transplantation. (frontiersin.org)
PHILADELPHIA (February 8, 2017) - The Fox Chase-Temple University Hospital Bone Marrow Transplant Program has received internationally-recognized reaccreditation by the Foundation for the Accreditation of Cellular Therapy (FACT) at the University of Nebraska Medical Center. (foxchase.org)
FACT is an internationally-recognized accrediting body for hospitals and medical institutions offering stem cell transplant, and indicates the accredited institution has met the most rigorous standards in every aspect of stem cell therapy. (foxchase.org)
FACT-JACIE Standards are defined by leading experts based on the latest knowledge of the field of cellular therapy transplantation. (foxchase.org)
In December 1994, the International Society for Cellular Therapy (ISCT) and the American Society for Blood and Marrow Transplantation (ASBMT) merged their Standards into a single document covering all aspects of hematopoietic cell therapy (collection, processing, and transplantation). (foxchase.org)
JACIE was founded by the European Group for Blood and Marrow Transplantation (EBMT) and the International Society for Cellular Therapy (ISCT), the two leading scientific organizations involved with cellular transplantation in Europe. (foxchase.org)
I hear a lot of questions about stem cell therapy, such as "what is the source of stem cells used in MS research? (mssociety.ca)
and, "what are the risks and benefits of stem cell therapy? (mssociety.ca)
No obvious correlations between clinical parameters, including age, karyotype, existence of paroxysmal nocturnal hemoglobinuria clones, pretreatment blood counts, progenitor cell counts, and the response to immunosuppressive therapy (IST), were found. (springermedizin.at)
We also examined the numbers of colony-forming progenitor cells (CFUs) before and after therapy. (springermedizin.at)
The transplantation of human tissues, organs or cells is an established form of treatment that has been acknowledged as the best and very often only life-saving therapy for several serious and life-threatening congenital, inherited and acquired diseases and injuries. (who.int)

From then until the end of this preliminary clinical trial, Peters had transplanted and treated more cases and also obtained significant remissions similar to that of this woman's. (wikipedia.org)
In clinical trials, stem cell transplantation reduced the CD activity index (SMD − 2.10, P = 0.000), the CD endoscopic index of severity (SMD − 3.40, P = 0.000) and simplified endoscopy score for CD (SMD − 1.71, P = 0.000) and improved the inflammatory bowel disease questionnaire score (SMD 1.33, P = 0.305) compared to control values. (biomedcentral.com)
A randomized clinical trial at Memorial Sloan Kettering Cancer Center (MSK) has shown that fecal microbiota transplants (FMTs) can reestablish the health-promoting bacteria that are often damaged by intense antibiotic treatment in people who have stem cell or bone marrow transplants for blood cancer. (mskcc.org)
National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines also recommend the use of serum free light chain assay and plasma cell fluorescence in situ hybridization (FISH) on bone marrow: del 13, del 17p13, t(4;14), t(11;14), t(14;16), t(14;20), 1q21 amplification, 1p deletion as part of the initial diagnostic workup. (medscape.com)

and umbilical cord blood (PUCB), capable of 2017), associated with the results of the procedure restoring spinal cord function and immunology of and require a process of hospitalization and patients with indication for transplantation, with the prolonged hospital recovery. (bvsalud.org)
Indication AiPSC-RPE cell product will be indicated for the treatment of maculopathies related to RPE atrophy. (ca.gov)
Therapeutic Candidate or Device Autologous hematopoietic stem cells transduced with a HexA/HexB expressing lentiviral vector Indication Tay-Sachs disease Therapeutic Mechanism The transplanted gene modified autologous hematopoietic stem cells will engraft in the bone marrow and start producing HexA/HexB expressing immune progeny. (ca.gov)
Therapeutic Candidate or Device Hematopoietic stem and progenitor cells collected from X-CGD patients modified with a highly regulated lentiviral vector Indication X-linked Chronic Granulomatous Disease Therapeutic Mechanism Lentiviral vector (LV) modification of autologous hematopoietic stem and progenitor cells (HSPCs) to restore physiologic gp91phox expression. (ca.gov)

1 Improvements in transplantation techniques, including the wider use of cell selection, have contributed to a significant reduction in the morbidity and mortality associated with conventional transplantation. (bdbiosciences.com)

Thomas has been diagnosed with sickle cell disease which affects the red blood cells and needs an urgent Stem cell transplant but it was not available in his country. (gomedii.com)
Impact of disease burden at time of allogeneic stem cell transplantation in adults with acute myeloid leukemia and myelodysplastic syndromes. (uchicago.edu)
Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoietic stem cell transplant: reduced clearance at high doses and occurrence of late sinusoidal obstruction syndrome/veno-occlusive disease. (uchicago.edu)
Patterns and kinetics of T-cell chimerism after allo transplant with alemtuzumab-based conditioning: mixed chimerism protects from GVHD, but does not portend disease recurrence. (uchicago.edu)
Since its establishment in 2010, the Adult AML Working Group within the JSHCT has been using this registry data to complete several studies focusing on various aspects of HCT in adults with AML, with particular attention paid to patient-, disease-, and transplantation-related factors. (apbmt.org)
The 5-year probability of overall survival (OS) after allogeneic HCT was estimated to be 56% (95% confidence interval[CI], 55%- 57%) for patients receiving a transplant while in CR, and 22% (95% CI, 21%-23%) for those who were experiencing active disease. (apbmt.org)
Impact Treatment of the cancer stem cell driven disease Acute Myelogenous Leukemia (AML) will be impacted. (ca.gov)
Immune Reconstitution After Autologous Hematopoietic Stem Cell Transplantation in Crohn's Disease: Current Status and Future Directions. (wizaxe-prod.com)
Improving safety of autologous haematopoietic stem cell transplantation in patients with Crohn's disease. (wizaxe-prod.com)
She hasn't taken any disease-modifying medication because the stem cell transplant and has had extra time in lasting remission longer than when herdisease was lively. (healthgienic.com)
The first recorded fetal tissue transplants were in 1921 in the UK, in a failed attempt to treat Addison's disease, [1] and in 1928 in Italy, in a failed attempt to treat cancer. (lozierinstitute.org)

Umbilical cord hematopoietic stem cell transplantation has been restricted mainly to children because there are too few stem cells in umbilical cord blood for an adult. (msdmanuals.com)
[3] Today, patients take insulin shots and pharmaceuticals to control their diabetes, and adult stem cell transplants have shown success at ameliorating the condition. (lozierinstitute.org)
Adult stem cells exist in many adult tissues and although some go on to develop into tissues, others stay as stem cells which makes them easier to extract from the body. (mssociety.ca)
1,2 Regarding the origin, they can be classified as embryonic stem cells (ESCs) and adult stem cells (ASCs). (bvsalud.org)

CD patients maintained high remission rates for 3-24 months after transplantation. (biomedcentral.com)
After treatment with adrenocortical steroid and anti-human thymocyte globulin, his symptoms gradually improved, and he was discharged 15 months after transplantation on oral prednisolone 25 mg/day. (biomedcentral.com)

Allogeneic stem cell transplant in renal failure: engraftment and prolonged survival, but high incidence of neurologic toxicity. (uchicago.edu)

Diseases treatable by transplants. (mayoclinic.org)
In recent years, developments in stem cell (SC) biology and regenerative medicine have revealed that SCs unexpectedly can be used to treat autoimmune diseases. (biomedcentral.com)
The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
European Society for Blood and Marrow Transplantation (EBMT) Autoimmune Diseases Working Party (ADWP). (wizaxe-prod.com)
[ 1 ] First described in 1848, MM is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance ( MGUS ) to plasma cell leukemia. (medscape.com)
The bone marrow transplant is the last alternative generally recommended by the physicians in the cases of fatal bone marrow diseases and bone or skin cancer. (powershow.com)
The growing amount of bone marrow diseases will help in escalating the growth of the bone marrow market. (powershow.com)
8,9 Because dental stem cells (DSCs) are easy to obtain and present a great potential of differentiation, there has been a growing interest in their use in regenerative medicine for treatment of various human diseases. (bvsalud.org)

Each participating center is required to register all consecutive HCTs, report core information for registered HCTs as of post-transplant day 100, and report follow-up information annually. (apbmt.org)
The post-transplant course was uneventful. (frontiersin.org)
At 4 years of age and 29 months post-transplant, the patient demonstrated normal T-lymphocyte and natural killer cell numbers. (frontiersin.org)

The aim of the academic journal is to provide a platform for researchers, scientists, physicians, and other health professionals to find latest research information in the areas of stem cell research, transplantations such as stem cell transplantation, transplantation immunology, kidney transplantation and its treatment. (slideshare.net)
Chronic consequences of the treatment included development of leukemias and lymphomas and heightened vulnerability to infections soon after the transplant. (wikipedia.org)
Autologous Bone Marrow Treatment in India, is one of the most recent demands of many of our patients from Congo and the Middle east. (gomedii.com)
How is Autologous Bone Marrow Treatment in India done and what is the cost of Autologous Bone Marrow Treatment in India? (gomedii.com)
Bone marrow in general is an expensive affair, this is because the treatment is not provided everywhere. (gomedii.com)
Autologous Bone Marrow Treatment in India is an ideal one with one of the best oncologists for your treatment. (gomedii.com)
Thomas decided to travel to India where he will go through pre-treatment procedures of Blood tests and stem cell biopsy. (gomedii.com)
Wondering how an Autologous bone marrow transplant can help you solve the treatment options for multiple myeloma? (gomedii.com)
Before the transplant, drug treatment is used to reduce the number of myeloma cells in the patient's body. (gomedii.com)
http://www.cancer.gov/about-cancer/treatment/types/stem-cell-transplant/stem-cell-fact-sheet. (mayoclinic.org)
Past patients of Max Healthcare are well impressed by the treatment results of Bone marrow transplants. (bonemarrowtransplantations.com)
Intending to enhance the quality of life for patients and their families, the Center provides top-notch treatment facilities utilizing cutting-edge technology and cutting-edge medicines to treat the majority of complicated illnesses requiring allogeneic transplantation. (bonemarrowtransplantations.com)
Hematopoietic cell transplantation (HCT) is an integral part of the treatment of acute myeloid leukemia (AML). (apbmt.org)
Hematopoietic cell transplantation (HCT) is an effective treatment in patients with acute myeloid leukemia (AML). (apbmt.org)
Individuals with MS who get stem cell transplants would possibly get "potent illness management advantages" that last as long as 10 years without having for added treatment, he says. (healthgienic.com)
Eight patients (16 %) did not respond to treatment, and one died shortly after transplantation. (springermedizin.at)
Together, both IST and stem cell transplantation are reasonable treatment options for patients with AA. (springermedizin.at)
Organ transplantation is often the best, if not the only, treatment for acute and chronic organ failure. (who.int)
Kidney transplantation is a far more favourable treatment modality versus dialysis in terms of survival, quality of life and cost-effectiveness. (who.int)
Treatment selection takes into account patient age, fitness, and whether autologous stem cell transplantation (ASCT) is planned. (medscape.com)
Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium. (cdc.gov)
These cells have been studied for the treatment of periodontitis, bone repair, regeneration of the pulp after necrosis as well as the development of new teeth. (bvsalud.org)

Performance status and comorbidity predict transplant-related mortality after allogeneic hematopoietic cell transplantation. (uchicago.edu)
Late mortality in survivors of autologous hematopoietic-cell transplantation: report from the Bone Marrow Transplant Survivor Study. (qxmd.com)
Although mortality rates approach that of the general population after 10 years in certain subgroups, long-term survivors of autologous HCT continue to face challenges affecting their health and well-being. (qxmd.com)

The benefits of human tissue transplantation can be seen in both children and adults, including in survival rates following severe burn trauma, recovery of movement, closure of chronic wounds, rehabilitation of heart function and restoration of sight. (who.int)

The cells for a cord blood transplant come from an umbilical cord collected at birth by the MD Anderson Cord Blood Bank . (mdanderson.org)

Quantitating the CD34+ cell population can also be useful during mobilization as well as for determining the optimal timing of apheresis sessions to make sure that enough CD34+ cells have been harvested. (bdbiosciences.com)

The bone marrow market is expected to gain market growth in the forecast period of 2021 to 2028. (powershow.com)

The use of umbilical cord blood (UCB) has been steadily increasing, and UCB transplantation (UCBT) currently accounts for one-third of all allogeneic HCTs. (apbmt.org)
The technique for umbilical cord hematopoietic stem cell transplantation is still in its infancy, but it is gaining interest. (msdmanuals.com)
MSCs can be isolated from different locations, such as bone marrow, umbilical cord, placenta, adipose and dental tissues. (bvsalud.org)

Anatomy30

Organisms15

Diseases56

Chemicals and Drugs38

Analytical, Diagnostic and Therapeutic Techniques and Equipment76

Psychiatry and Psychology2

Phenomena and Processes39

Anthropology, Education, Sociology and Social Phenomena2

Information Science4

Named Groups6

Health Care17

Chemotherapy27

Donor29

AHSCT4

Mesenchymal13

Lymphoma12

Graft-versus-3

High-dose3

Outcomes12

Progenitor cell transplantation1

20161

Solid Tumors1

Relapse8

HSCT16

Recipients8

Peripheral blood stem5

Patient's own cells1

Found in the bone ma1

Allogeneic or autologous2

Blood stem cells5

20181

Centers6

Tumors2

Replace bone marrow1

Newly diagnosed2

Donors2

Refractory13

Allogenic3

Malignancies3

Immune system3

Efficacy1

Multiple sclerosis4

Disorders4

Therapy23

Clinical4

Indication4

Morbidity and morta1

Disease11

Adult4

Months after transplantation2

Engraftment1

Diseases8

Post-transplant3

Treatment22

Mortality3

Survival1

Cord blood transplant1

Apheresis1

20211

Umbilical cord3