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  • cell
  • MSCs (1×10 6 cells/kg) were administered by venous infusion within 6 h proceeding stem cell infusion on day 01 then on day +14 (figure 1). (confex.com)
  • biology
  • Pharmacologic inhibition of Cdc42 reversed HSC aging and restored function similar to that of younger stem cells, explained Hartmut Geiger, PhD, the study's principal investigator and a researcher in the Division of Experimental Hematology/Cancer Biology at Cincinnati Children's, and the Department of Dermatology and Allergic Diseases, Ulm University Medicine. (redorbit.com)
  • distinct
  • This view was first challenged by the 2002 discovery by the Muller-Sieburg group in San Diego, who illustrated that different stem cells can show distinct repopulation patterns that are epigenetically predetermined intrinsic properties of clonal Thy-1lo Sca-1+ lin− c-kit+ HSC. (wikipedia.org)
  • congenital
  • Candidates for HSCTs include pediatric cases where the patient has an inborn defect such as severe combined immunodeficiency or congenital neutropenia with defective stem cells, and also children or adults with aplastic anemia who have lost their stem cells after birth. (wikipedia.org)
  • More than 25,000 hematopoietic stem cell transplantations (HSCTs) are performed each year for the treatment of lymphoma, leukemia, immune-deficiency illnesses, congenital metabolic defects, hemoglobinopathies, and myelodysplastic and myeloproliferative syndromes. (dovepress.com)
  • The discovery has implications for developing stem cell-based therapies for diseases like leukemia and congenital blood disorders. (redorbit.com)
  • epithelial
  • G. Nigro, R. Rossi, P. H. Commere, P. Jay, P. J. Sansonetti, The cytosolic bacterial peptidoglycan sensor Nod2 affords stem cell protection and links microbes to gut epithelial regeneration. (sciencemag.org)
  • Survival
  • who found that signaling induced by a microbe-derived agonist of NOD2 promoted survival of intestinal stem cells and improved their resistance to oxidative stress-induced cell death. (sciencemag.org)
  • vitro
  • France prohibits reproductive cloning and embryo creation for research purposes, but enacted laws (with a sunset provision expiring in 2009) to allow scientists to conduct stem cell research on imported a large amount of embryos from in vitro fertilization treatments. (wikipedia.org)
  • research
  • BioInformant is the first and only market research firm to specialize in the stem cell industry. (stemcellcordblood.net)
  • The European Union has yet to issue consistent regulations with respect to stem cell research in member states. (wikipedia.org)
  • Germany has restrictive policies for stem cell research, but a 2008 law authorizes "the use of imported stem cell lines produced before May 1, 2007. (wikipedia.org)
  • According to modern stem cell researchers, Spain is one of the leaders in stem cell research and currently has one of the most progressive legislations worldwide with respect to hESC research. (wikipedia.org)
  • The United Kingdom is one of the leaders in stem cell research, in the opinion of Lord Sainsbury, Science and Innovation Minister for the UK. (wikipedia.org)
  • A new £10 million stem cell research centre has been announced at the University of Cambridge. (wikipedia.org)
  • allows
  • Italy has a 2004 law that forbids all sperm or egg donations and the freezing of embryos, but allows, in effect, using existing stem cell lines that have been imported. (wikipedia.org)
  • Sweden forbids reproductive cloning, but allows therapeutic cloning and authorized a stem cell bank. (wikipedia.org)