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  • recombinant
  • Functional reconstitution of kinase activity by recombinant Jak3 using Jak3-wt or villin/gelsolin-wt as substrate showed that Jak3 autophosphorylation was the rate-limiting step during interactions between Jak3 and cytoskeletal proteins. (wikipedia.org)
  • HSCT
  • Adult recipients of an allo-HSCT experience deficiencies in their B and T cell reconstitution, which can persist for over a year, and are associated with an Increased risk of infection, relapse, and secondary malignancies. (grantome.com)
  • mortality
  • Hematopoietic acute radiation syndrome (H-ARS) is characterized by severe myelosuppression, which increases the risk of infection, bleeding, and mortality. (jci.org)
  • factors
  • GATA factors belong to an evolutionarily conserved family of C4 zinc finger transcription factors that play demonstrably crucial roles in quite diverse developmental programs, including hematopoietic, urogenital, otic, and neuronal developmental elaboration ( 1 - 11 ). (pubmedcentralcanada.ca)
  • early
  • The CD34 protein is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. (wikipedia.org)
  • receptors
  • Both LIFR and gp130 are members of a family of cytokine receptors that includes components of the receptors for the majority of hematopoietic cytokines and for cytokines that affect other systems, including the ciliary neurotrophic factor, growth hormone and prolactin. (wikipedia.org)