Myelodysplastic SyndromesMyeloproliferative DisordersJanus Kinase 2Primary MyelofibrosisHematopoiesisMyelodysplastic-Myeloproliferative DiseasesPolycythemia VeraThrombocythemia, EssentialSyndromeAnemia, RefractoryLeukemia, Myelomonocytic, ChronicReceptors, ThrombopoietinBone Marrow NeoplasmsAnemia, Refractory, with Excess of BlastsLeukemia, Myeloid, AcuteThrombocytosisHematopoiesis, ExtramedullaryBone MarrowHematopoietic Stem CellsLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeLeukemia, MyeloidMutationLeukemia, Myelomonocytic, JuvenileAnemia, SideroblasticChromosomes, Human, Pair 5SplenomegalyProto-Oncogene Proteins c-cblHematologic NeoplasmsBone Marrow CellsLeukemiaLeukemia, Myelogenous, Chronic, BCR-ABL PositiveAzacitidineKaryotypingBone Marrow DiseasesMyeloid Progenitor CellsPrognosisPhiladelphia ChromosomeBlast CrisisDown SyndromeChromosome AberrationsPreleukemiaHematologyMegakaryocytesMonosomyMyelopoiesisDNA Mutational AnalysisTreatment OutcomeJanus KinasesPancytopeniaMegakaryocyte-Erythroid Progenitor CellsSTAT5 Transcription FactorMegakaryocyte Progenitor CellsThalidomideAnemia, AplasticChromosomes, Human, Pair 7Metabolic Syndrome XAntigens, CD34Mutation, MissenseCell Transformation, NeoplasticDisease ProgressionClonal EvolutionAcute DiseaseColony-Forming Units AssayChromosome DeletionCore Binding Factor Alpha 2 SubunitHematopoietic Stem Cell TransplantationCytogenetic AnalysisProto-Oncogene ProteinsNeoplasms, Second PrimaryGene Knock-In TechniquesErythroid Precursor CellsGranulocyte Precursor CellsFusion Proteins, bcr-ablGranulocytesAmino Acid SubstitutionPoint MutationErythropoiesisCell ProliferationPhenotypeErythropoietinBlood Cell CountAntineoplastic AgentsProtein Kinase InhibitorsBone Marrow TransplantationTrisomyErythroid CellsCytogeneticsHematologic DiseasesTranslocation, GeneticDNA-Binding ProteinsNeoplasmsFlow CytometryChromosomes, Human, Pair 8Signal TransductionAntimetabolites, AntineoplasticNephrotic SyndromeMice, Inbred C57BLGranulocyte Colony-Stimulating FactorPolymerase Chain ReactionTransplantation, Homologous