• CT scanning is rarely of value, yet it may define the anatomy of change in complex bones and confirm the diagnosis of extramedullary hematopoiesis. (medscape.com)
  • Immunohistochemistry with MPO and CD61 applied to the histological findings made the diagnosis of extramedullary hematopoiesis (Figure 3). (clinmedjournals.org)
  • Hematopoiesis also takes place in many other tissues or organs such as the yolk sac, the aorta-gonad mesonephros (AGM) region, and lymph nodes. (wikipedia.org)
  • Characterizing the development of known markers of posterior ocular vascular-hematopoiesis-like tissues of lumpfish is important to gain a better understanding of ocular tissue development, homeostasis, and response to stress as well as provide new basic knowledge on these markers. (mun.ca)
  • Here we report that mutation in a conserved endocytic protein Asrij affects signal transmission and causes aberrant lymph gland hematopoiesis. (nih.gov)
  • Extramedullary hematopoiesis was noted in the sublumbar and mesenteric lymph nodes. (vin.com)
  • Diffuse expansion of osseous medullary spaces, coarsened trabeculations of the ribs and vertebrae, and paravertebral extramedullary hematopoiesis. (radiopaedia.org)
  • Thus, an IFN-γ-dependent loop drives liver ILC1 development in situ, highlighting the contribution of extramedullary hematopoiesis to regional immune composition within the liver. (nih.gov)
  • For now, preclinical studies showed that tumor growth in melanoma seems to play a critical role in reprogramming the host immune system by regulating hematopoiesis, which might be associated with the expansion of immunosuppressive cells such as tumor-associated macrophages, regulatory T cells, and myeloid-derived suppressor cells (MDSCs) ( 7 ). (snmjournals.org)
  • However, the 5C6 stroma which failed to support hematopoiesis uniquely expressed several inhibitors of the WNT pathway. (edu.au)
  • Unfortunately, the majority of these EPCs not only fail to support normal hematopoiesis but also acquire pro-tumorigenic properties. (cancerbiomed.org)
  • I propose that the development of the posterior vasculature and hematopoiesis system of the lumpfish eye involves unique expression markers that exaggerate and support natural extramedullary hematopoiesis in ocular vascular structures. (mun.ca)
  • 1. Alveolar airspace and pulmonary artery involvement by extramedullary hematopoiesis: a unique manifestation of myelofibrosis. (nih.gov)
  • 2. Diffuse pulmonary extramedullary hematopoiesis in a patient with myelofibrosis: CT findings. (nih.gov)
  • 3. Tc-99m sulfur colloid demonstration of diffuse pulmonary interstitial extramedullary hematopoiesis in a patient with myelofibrosis. (nih.gov)
  • 5. Cutaneous extramedullary hematopoiesis in myelofibrosis. (nih.gov)
  • 6. Massive ascites caused by peritoneal extramedullary hematopoiesis as the initial manifestation of myelofibrosis. (nih.gov)
  • 7. JAK2-positive cutaneous myelofibrosis presenting as sclerosing extramedullary hematopoietic tumors on the scalp: case presentation and review of the literature. (nih.gov)
  • 8. Idiopathic myelofibrosis accompanied by peritoneal extramedullary hematopoiesis presenting as refractory ascites in a dog. (nih.gov)
  • 9. Cutaneous myelofibrosis with JAK2 V617F mutation: metastasis, not merely extramedullary hematopoiesis! (nih.gov)
  • 11. [A case of cutaneous extramedullary hematopoiesis associated with idiopathic myelofibrosis]. (nih.gov)
  • 13. Transforming growth factor-beta overexpression in cutaneous extramedullary hematopoiesis of a patient with myelodysplastic syndrome associated with myelofibrosis. (nih.gov)
  • 14. Cutaneous extramedullary hematopoiesis in a patient with acute myelofibrosis. (nih.gov)
  • 16. Assessment of sites of marrow and extramedullary hematopoiesis by hybrid imaging in primary myelofibrosis patients. (nih.gov)
  • 18. [Cutaneous extramedullary hematopoiesis in myelofibrosis]. (nih.gov)
  • 19. Idiopathic myelofibrosis with extramedullary hematopoiesis in the kidneys. (nih.gov)
  • 20. [Idiopathic myelofibrosis with extramedullary hematopoiesis foci in the skin and testicles. (nih.gov)
  • Yang , Ming et al " 99m Tc-Sulfur Colloid Bone Marrow Scintigraphy in Diagnosis of Diffuse Pulmonary Extramedullary Hematopoiesis Secondary to Myelofibrosis. (snmjournals.org)
  • Later, they migrate to the fetal liver where the majority of physiologic EMH (extra-medullary hematopoiesis) takes place. (wikipedia.org)
  • We are very excited by these new data with ALN-TMP where we have demonstrated disease modifying effects in models of β-thalassemia, including amelioration of anemia, iron overload, extra-medullary hematopoiesis, and ineffective erythropoiesis, in addition to correction of globin gene expression. (aol.com)
  • Indeed, our studies show that ALN-TMP administration results in reduced iron overload, decreased extra-medullary hematopoiesis, increased hemoglobin levels, and a reduction in ineffective erythropoiesis. (aol.com)
  • Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk. (harvard.edu)
  • SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation. (harvard.edu)
  • Familial Clonal Hematopoiesis in a Long Telomere Syndrome. (harvard.edu)
  • Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk. (harvard.edu)
  • Clonal hematopoiesis: Mutation-specific adaptation to environmental change. (ucdenver.edu)
  • Foci of extramedullary hematopoiesis were common in congenital nonprogressive hemangioma (presumably reflective of the young age of these infants, all younger than 4 months). (jamanetwork.com)
  • The aim of this study was to report the extramedullary hematopoiesis as a complication of filgrastim usage in a child with acute colchicine intoxication. (nih.gov)
  • Figure 2 Extramedullary hematopoiesis-arrow indicates erythroid cells, and arrowhead indicates a megakaryocyte, in a female Harlan Sprague-Dawley rat from a chronic study. (nih.gov)
  • This graph shows the total number of publications written about "Hematopoiesis" by people in Harvard Catalyst Profiles by year, and whether "Hematopoiesis" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Hematopoiesis" by people in Profiles. (harvard.edu)
  • Depending on the underlying cause, patients may have abnormalities in blood production and associated extramedullary hematopoiesis. (bmj.com)
  • Hematopoiesis is more commonly known as blood cell production. (thayerbirding.com)
  • Figure 1 Extramedullary hematopoiesis-arrows indicate erythroid cells in a female Harlan Sprague-Dawley rat from a chronic study. (nih.gov)
  • Figure 3 Extramedullary hematopoiesis in a male B6C3F1 mouse from a chronic study. (nih.gov)
  • Bizarre purple macules and papules, which represent persistent dermal (extramedullary) hematopoiesis, are seen in the skin. (medscape.com)