• motifs d'acides aminés (fr) Three-dimensional protein structural elements that are composed of a combination of secondary structures. (wikimedia.org)
  • As observed in all Nudix hydrolase structures, the α -helix of the highly conserved `Nudix box' in Bh --MutT is one of two helices that sandwich a four-stranded mixed β -sheet with the central two β -strands parallel to each other. (iucr.org)
  • Our results indicate that olig3 has an essential proneural activity in the dorsal spinal cord and cooperates with the Delta/Notch regulatory loop to establish the boundary between the neural crest and the lateral neural plate. (zfin.org)
  • We found that modification of a single amino acid in the EF-hand motif greatly affected the protein's Ca 2+ sensitivity and substrate preference, demonstrating the role of this motif in Ca 2+ regulation of TbPI-PLC. (asm.org)
  • Catalysis depends on the conserved 23-amino acid Nudix motif (Nudix box), G-x(5)-E-x(5)-[UA]-x-R-E-x(2)-E-E-x-G-U, where U is an aliphatic, hydrophobic residue. (embl.de)