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Helicobacter pyloriHelicobacter InfectionsHelicobacterGastritisGastric MucosaHelicobacter hepaticusUreaseHelicobacter heilmanniiStomachPeptic UlcerClarithromycinMetronidazoleAmoxicillinDyspepsiaBacterial ProteinsAnti-Ulcer AgentsOmeprazoleStomach NeoplasmsAntigens, BacterialStomach DiseasesGastritis, AtrophicBismuthPyloric AntrumStomach UlcerBreath Tests2-PyridinylmethylsulfinylbenzimidazolesAnti-Bacterial AgentsAntibodies, BacterialGastroscopyLansoprazoleDNA, BacterialProton Pump InhibitorsDrug Therapy, CombinationMetaplasiaPolymerase Chain ReactionTinidazoleLewis Blood-Group SystemPepsinogen ABiopsyGerbillinaeUreaRanitidineMolecular Sequence DataEndoscopy, GastrointestinalDuodenitisFurazolidoneHelicobacter mustelaeLymphoma, B-Cell, Marginal ZoneCytotoxinsRNA, Ribosomal, 16SGastrinsRabeprazoleGastric AcidGastric MucinsAntacidsPepsinogensPepsinogen CTetracyclineAntitrichomonal AgentsNitroreductasesGenes, BacterialImmunoglobulin GPenicillinsVirulenceSequence Analysis, DNAVirulence FactorsParietal Cells, GastricFecesBacterial AdhesionSulfoxidesEndoscopy, Digestive SystemDNA, RibosomalCampylobacterDrug Resistance, BacterialOrganometallic CompoundsGastric JuiceEnzyme-Linked Immunosorbent AssayRNA, Ribosomal, 23SGastrointestinal DiseasesBase SequenceHepatitis, AnimalAchlorhydriaAntigens, CD15Genomic IslandsGenome, BacterialSeroepidemiologic StudiesPhylogenySensitivity and SpecificityEpithelial CellsPeptic Ulcer HemorrhageInterleukin-8Adhesins, BacterialPrevalenceGastroesophageal RefluxMicrobial Sensitivity TestsGene Expression Regulation, BacterialColony Count, MicrobialChronic DiseaseRNA, BacterialSpecies Specificity
Gastric cancer2023EradicationAbstractScreened for Helicobacter pyloriGastritis and Helicobacter pyloriInfectionsAnti-Helicobacter pyloriPylori-associatedPathogenCampylobacterBacteriumHumansResistance to clarithromycin2001AntibodiesGenusPrevalenceChronicHeilmanniiTransgenic miceBacteriaInfection in patientsBiomarkersProteinsAtrophySpeciesD'uneGastriteBacterial infectionStomachGastrointestinalEpidemiologySerumSystemicCarcinogenesisPatientsVitro2000SignificantlyArticleResearchersChildrenTherapies
Gastric cancer9
  • Chronic gastritis is the major cause of human gastric cancer caused by the Gram-negative bacterium Helicobacter pylori . (nature.com)
  • Helicobacter pylori infection causes a variety of gastrointestinal diseases, including peptic ulcers and gastric cancer. (rcsb.org)
  • We have built a model for gastric cancer predisposition caused by hypergastrenimia during Helicobacter infection. (benthamscience.com)
  • Helicobacter pylori overgrowth in the gastrointestinal tract is a contributor to the formation of gastric ulcers, gastric cancer, and a unique lymphoma involving the gut mucosa (mucosal-associated lymphatic tissue lymphoma). (naturalmedicinejournal.com)
  • Since we have published Fat -1 transgenic mice overexpressing 3-desaturase significantly mitigated Helicobacter pylori (H. pylori) -associated gastric pathologies including rejuvenation of chronic atrophic gastritis and prevention of gastric cancer, in this study, we have explored the underlying molecular mechanisms of walnut against H. pylori infection. (nuthealth.org)
  • Helicobacter pylori evolution during progression from chronic atrophic gastritis to gastric cancer and its impact on gastric stem cells. (medscape.com)
  • Association of Helicobacter pylori infection with gastric cancer. (medscape.com)
  • Scientists from the International Agency for Research on Cancer (IARC) and partner institutions in the United Kingdom and China undertook a case-cohort study nested within the prospective China Kadoorie Biobank to measure Helicobacter pylori biomarkers and estimate the number of cases of gastric cancer attributable to H. pylori infection in China. (who.int)
  • Small Extracellular Vesicles Derived from Helicobacter Pylori-Infected Gastric Cancer Cells Induce Lymphangiogenesis and Lymphatic Remodeling via Transfer of miR-1246. (bvsalud.org)
20232
  • Fast Five Quiz: Management of Helicobacter pylori - Medscape - Oct 18, 2023. (medscape.com)
  • The following is a summary of " Global prevalence of Helicobacter pylori infection between 1980 and 2022: a systematic review and meta-analysis ," published in the June 2023 issue of Gastroenterology & Hepatology by Li et al. (physiciansweekly.com)
Eradication8
  • Helicobacter pylori antigen testing is approved by the US Food and Drug Administration (FDA) for use as a noninvasive diagnostic test for H pylori infection and as a test to determine eradication after treatment. (medscape.com)
  • OBJECTIVE: To evaluate the efficacy of rescue therapy using rifabutin, amoxicillin and a proton pump inhibitor (PPI) in the eradication of Helicobacter pylori in patients who have failed at least one course of PPI-based triple therapy.METHODS: The present study was a single-centre case series of 16 consecutive patients who had received at least one course of standard eradication therapy. (hindawi.com)
  • THURSDAY, May 7, 2020 (HealthDay News) -- A novel rifabutin-based triple therapy (RHB-105) is effective for eradication of Helicobacter pylori , with eradication rates unaffected by resistance to clarithromycin or metronidazole, according to a study published online May 5 in the Annals of Internal Medicine . (healthday.com)
  • Eradication of Helicobacter pylori helps prevent ulcer recurrence in patients with duodenal or gastric ulcers but its value is less clear in those with other causes of dyspepsia. (bmj.com)
  • Besides, in "Sixth National Guidelines for the Treatment of Helicobacter pylori Infection 2022" , experts propose that semi-synthetic tetracycline can be used in eradication treatment instead of tetracycline. (biomedcentral.com)
  • Moxifloxacin-containing triple therapy as second-line treatment for Helicobacter pylori infection: effect of treatment duration and antibiotic resistance on the eradication rate. (medscape.com)
  • Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial. (medscape.com)
  • Aanpreung P. Suggestive parameters for eradication therapy in children with Helicobacter pylori gastritis. (medscape.com)
Abstract2
  • article{647bc080-7535-4010-966a-3d1fad12c300, abstract = {{The binding of iodine-labelled plasminogen to Helicobacter pylori CCUG 17874 was characterized. (lu.se)
  • ABSTRACT In this study, endoscopy patients with and without chronic liver disease (CLD) were examined and tested for Helicobacter pylori infection by detecting the presence of serum and salivary anti-H. pylori antibody. (who.int)
Screened for Helicobacter pylori1
  • A total of 631 serum samples collected in 1969, 1979, and 1989 from adults and children were screened for Helicobacter pylori by Western blot analysis. (nih.gov)
Gastritis and Helicobacter pylori1
Infections4
  • Helicobacter infections have also been confirmed in stranded sea otters by PCR. (vin.com)
  • Helicobacter pylori tests are used to diagnose stomach infections caused by the bacterium, Helicobacter pylori (previously known as Campylobacter pylori), which are associated with gastritis (stomach inflammation), ulcers of the stomach or first part of the small intestine, and, in some cases, cancer. (medicaldevice-network.com)
  • Helicobacter pylori is one of the most common chronic bacterial infections worldwide. (medscape.com)
  • Helicobacter pylori ( H. pylori ) infection is one of the most common bacterial infections, affecting approximately 50% of the global population [ 1 ]. (biomedcentral.com)
Anti-Helicobacter pylori2
  • Can vitamin B6 alleviate the adverse reactions of quadruple anti-Helicobacter pylori regimen? (biomedcentral.com)
  • To evaluate whether vitamin B6 can alleviate the adverse reactions caused by the quadruple anti- Helicobacter pylori treatment regimen containing minocycline and metronidazole. (biomedcentral.com)
Pylori-associated1
  • 2005) Invasive and non invasive diagnosis of Helicobacter pylori-associated atrophic gastritis: A comparative study. (scirp.org)
Pathogen3
  • Helicobacter pylori: A foodborne pathogen? (wjgnet.com)
  • One important factor that promotes the colonization of the upper digestive system of the human pathogen Helicobacter pylori is its helical cell shape. (uni-marburg.de)
  • The complete genome sequence of the gastric pathogen Helicobacter pylori. (medscape.com)
Campylobacter4
Bacterium5
  • The bacterium Helicobacter pylori ( H. pylori ) infects the stomachs of approximately 50% of all humans. (wjgnet.com)
  • Helicobacter pylori is a Gram-negative bacterium that causes chronic inflammations in the stomach area and is involved in ulcers, which can develop into gastric malignancies. (nature.com)
  • Helicobacter pylori (H. pylori) is a spiral-shaped bacterium found in the stomach, which (along with acid secretion) damages stomach and duodenal tissue, causing inflammation and peptic ulcers. (luriechildrens.org)
  • Helicobacter pylori ( H. pylori) is a gram-negative, microaerophilic curved or S-shaped bacterium that infects the inner lining of the stomach. (nccid.ca)
  • As the microorganism Helicobacter pylori is now accepted as the most common cause of human chronic gastritis, the present work was undertaken to verify a possible relationship between the presence of this bacterium and inflammatory changes of antral mucosa in chagasic patients. (scielo.br)
Humans5
  • H. heilmanni s.l.) is a grouping of non-H. pylori Helicobacter species that take as part of their definition a similarity to H. pylori in being associated with the development of stomach inflammation, stomach ulcers, duodenum ulcers, stomach cancers that are not lymphomas, and extranodal marginal B cell lymphoma of the stomach in humans and animals. (wikipedia.org)
  • The H. heilmani species identified to date in the stomachs of humans with the cited upper gastrointestinal tract diseases are: Helicobacter bizzozeronii, Helicobacter felis, Helicobacter salomonis, Helicobacter suis, and Helicobacter heilmannii s.s. (wikipedia.org)
  • Helicobacter pylori ( H. pylori ) is an organism that is widespread in the human population and is sometimes responsible for some of the most common chronic clinical disorders of the upper gastrointestinal tract in humans, such as chronic-active gastritis, duodenal and gastric ulcer disease, low-grade B-cell mucosa associated lymphoid tissue lymphoma of the stomach, and gastric adenocarcinoma, which is the third leading cause of cancer death worldwide. (wjgnet.com)
  • 3,4 All known helicobacters of humans and animals colonize the gastrointestinal tract. (vin.com)
  • 3,4 In humans, Helicobacter pylori is a significant cause of peptic ulcer disease and gastric tumors. (vin.com)
Resistance to clarithromycin1
  • Annual change of primary resistance to clarithromycin among Helicobacter pylori isolates from 1996 through 2008 in Japan. (medscape.com)
20011
  • 2001. Helicobacter typhlonius sp. (vin.com)
Antibodies1
  • The Wampole Laboratories (Wampole) H. pylori IgG Enzyme-Linked Immunosorbent Assays (ELISA) is intended for the detection and qualitative determination of IgG antibodies to Helicobacter pylori in human serum. (cdc.gov)
Genus3
  • Helicobacter is a genus of Gram-negative bacteria possessing a characteristic helical shape. (wikipedia.org)
  • published sufficient reasons to justify the new genus name Helicobacter. (wikipedia.org)
  • The genus Helicobacter contains about 35 species. (wikipedia.org)
Prevalence2
  • The helicobacter pylori tests market in Norway can expand or contract due to a variety of reasons including population demographics, disease incidence and prevalence, macroeconomic issues, and geopolitical considerations. (medicaldevice-network.com)
  • Limited research has been conducted to investigate the temporal patterns of Helicobacter pylori prevalence on a global scale. (physiciansweekly.com)
Chronic2
  • Helicobacter pylori has been shown to be the causative agent in chronic-active gastritis, and evidence has almost completely satisfied Koch's postulates for this organisms' pathogenicity in primary duodenal ulcers. (cdc.gov)
  • Helicobacter pylori is a chronic bacterial infection with significant global impact. (medscape.com)
Heilmannii1
Transgenic mice1
  • The model was built using publically available data form hypergastrenimic transgenic mice infected with Helicobacter. (benthamscience.com)
Bacteria1
Infection in patients1
  • Kokkola, A., Rautelin, H. and Puolakkainen, P. (1998) Positive result in serology indicates active Helicobacter pylori infection in patients with atrophic gastritis. (scirp.org)
Biomarkers1
  • Gastric colonization by Helicobacter pylori increases the risk of gastric disorders, including atrophic gastritis which can be diagnosed based on levels of serum biomarkers like Gastrin and Pepsinogen. (scirp.org)
Proteins3
  • Of these proteins, seven are found in all species of the family, while the remaining four are not found in any Helicobacter strains and are unique to Wollinella. (wikipedia.org)
  • Recent work characterizing cell shape mutants of Helicobacter pylori revealed a novel mechanism for the generation of a twisted helix from a rod, including PG-modifying enzymes as well as additional proteins such as the bactofilin homolog CcmA or the membrane proteins Csd5 and Csd7. (uni-marburg.de)
  • Functional analysis of the Helicobacter pylori flagellar switch proteins. (medscape.com)
Atrophy1
  • 1993) Apparent reversal of early gastric mucosal atrophy after triple therapy for Helicobacter pylori. (scirp.org)
Species4
  • Helicobacter species are able to thrive in the very acidic mammalian stomach by producing large quantities of the enzyme urease, which locally raises the pH from about 2 to a more biocompatible range of 6 to 7. (wikipedia.org)
  • 2,9 To date, at least two novel Helicobacter species have been identified from the gastric mucosa of stranded harp seals ( Phoca vitulina ) and the feces of California sea lions. (vin.com)
  • nov., a novel murine urease-negative Helicobacter species. (vin.com)
  • nov., a urease-positive Helicobacter species of dolphins and whales. (vin.com)
D'une1
  • RÉSUMÉ Dans cette étude, des patients soumis à une endoscopie et souffrant ou non d'une pathologie hépatique chronique (PHC) ont fait l'objet d'un examen et d'une recherche d'infection à Helicobacter pylori par détection de la présence d'anticorps anti-H. pylori dans le sérum et la salive. (who.int)
Gastrite1
  • Tendo em vista que o microrganismo Helicobacter pylori é hoje considerado a causa mais comum de gastrite crônica no homem, propôs-se a realização deste trabalho para se verificar a possibilidade de esta bactéria estar também associada com as alterações inflamatórias da mucosa gástrica em pacientes com a forma digestiva da doença de Chagas. (scielo.br)
Bacterial infection1
  • Helicobacter pylori infection is a bacterial infection that causes inflammation of your stomach lining and ulcers (sores) in your stomach or intestine. (msdmanuals.com)
Stomach1
  • Hom (Helicobacter outer membrane) family of OMPs in H. pylori consists of four members (HomA, B, C and D). In the H. pylori genome jhp 0870 open-reading frame (ORF) that codes for HomB outer membrane protein is associated with many stomach diseases and is a novel co-marker for peptic ulcer disease (PUD) 9 , 10 . (nature.com)
Gastrointestinal2
  • The non- H. pylori helicobacters: their expanding role in gastrointestinal and systemic diseases. (vin.com)
  • Helicobacter pylor i is a common occupant of the human gastrointestinal tract. (naturalmedicinejournal.com)
Epidemiology1
  • Fallone CA. Epidemiology of the antibiotic resistance of Helicobacter pylori in Canada. (medscape.com)
Serum1
  • Serum neutralizing antibody response to the vacuolating cytotoxin of Helicobacter pylori. (jci.org)
Systemic1
  • A population-based epidemiologic study of Helicobacter pylori infection and its association with systemic inflammation. (medscape.com)
Carcinogenesis1
  • Mechanism of Synergistic Carcinogenesis from Hypergastrinemia and Helicobacter Infection, Biological Models Volume Title: From Knowledge Networks to Biological Models (2012) 1: 131. (benthamscience.com)
Patients2
  • Helicobacter pylori infection influences symptomatic response to anti-secretory therapy in patients with GORD--crossover comparative study with famotidine and low-dose lansoprazole. (medscape.com)
  • Helicobacter pylori (H. pylori)-positive GC patients experience a higher rate of LNM than H. pylori-negative GC patients . (bvsalud.org)
Vitro1
  • Approximately 50% of Helicobacter pylori isolates produce a cytotoxin in vitro that induces vacuolation of eukaryotic cells. (jci.org)
20001
  • 2000. Isolation and characterization of a Helicobacter sp. (vin.com)
Significantly1
  • HOUSTON-(March 7, 2011)- Children without previous iron deficiencies or anemia who remained infected with Helicobacter pylori (H. pylori) had significantly lower levels of iron compared to children who had the infection eradicated, according to researchers at The University of Texas Health Science Center at Houston (UTHealth). (scienceblog.com)
Article1
  • Review article: associations between Helicobacter pylori and obesity - an ecological study. (medscape.com)
Researchers1
  • 1,10,11 It was hypothesized that Helicobacter infection may play a role in the development of gastric lesions in sea otters ( Enhydra lutris ) and California sea lions ( Zalophus californianus ) based on our previously published observations in cetaceans, as well as clinical and pathologic findings of captive and wild animals by researchers and veterinarians. (vin.com)
Children4
  • What is H. pylori (Helicobacter pylori) in children? (brighamandwomens.org)
  • Helicobacter pylori infection in children: update. (medscape.com)
  • Asymptomatic Helicobacter pylori infection and iron deficiency are not associated with decreased growth among Alaska Native children aged 7-11 years. (cdc.gov)
  • Alaska Native children have high Helicobacter pylori infection and iron deficiency prevalences, and their average height-for-age is lower than US reference populations. (cdc.gov)
Therapies2
  • 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial. (medscape.com)
  • Levofloxacin-based and clarithromycin-based triple therapies as first-line and second-line treatments for Helicobacter pylori infection: a randomised comparative trial with crossover design. (medscape.com)