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  • Thus
  • Thus, with respect to their special cell-surface mechanical features, HEK293 cells could be categorized into a new class distinct from normal stromal and cancer cells. (peerj.com)
  • Thus, analyzing the mechanical features of cells can reveal the characteristics of their underlying actin networks. (peerj.com)
  • types
  • Investigation of the mechanical features provides specific information about the different states and types of animal cells. (peerj.com)
  • AFM measurement has the potential to detect the surface stiffness of any adherent and suspended cell types. (peerj.com)
  • surface
  • Previously, we investigated the surface mechanics of cancer and normal stromal cells in adherent and suspended states using atomic force microscopy. (peerj.com)
  • Previously, we reported the surface mechanics and actin cytoskeleton architecture of normal stromal cells i.e., mesenchymal stem cells and normal fibroblasts, and cancer cells i.e. (peerj.com)
  • Control
  • We found that although TWEAK-overexpressing cells do not have a growth advantage in vitro , they form larger and more highly vascularized tumors in athymic mice when compared with control, vector-transfected cells. (aacrjournals.org)
  • important
  • Since they are involved in a broad range of crucial cell functions, they represent important therapeutic targets. (springer.com)