HypertensionDysfunctionCongestiveCause left ventricularConcentric hypertrophyMyocardial hypertrophyMeasuring left ventricular massHypertrophic cardiomyopathyArrhythmiasTetralogy of FalAsymptomaticEjection fractionRegressionAtherosclerosisRight ventricularValvular heart dSeptal defectCardiomegalyVentricle2023Coronary Heart DObesityOverloadHypertensive patientsEccentricAtrial enlargementWall thicknessSevere myocardialCardiomyopathyPathologySymptomsEtiologyShortness of breEchocardiographyMortalityPrevalenceGeometryCardiomyocytesTypicallyBlood vesselsFibrillationChronicAcuteFindingsStrokeMalignantCardiovascular diseasesAcutely decompensated heart failureLVMIPatientsSystoleSignificantlyDiseaseCardiac MRI
Hypertension25
- Concentric hypertrophy results from various stressors to the heart including hypertension, congenital heart defects (such as Tetralogy of Fallot), valvular defects (aortic coarction or stenosis), and primary defects of the myocardium which directly cause hypertrophy (hypertrophic cardiomyopathy). (wikipedia.org)
- Similarly, in systemic hypertension, the left ventricle must work harder to overcome the higher pressures of the vascular system and responds by thickening to deal with increased wall stress. (wikipedia.org)
- When stressors that encourage this concentric hypertrophy are reduced or eliminated (either surgically corrected in the case of cardiac defects, or hypertension is reduced from diet and exercise) it is possible for the heart to undergo 'reverse remodeling', returning to a somewhat more 'normal' state instead of progressing to a dilated, pathologic phenotype. (wikipedia.org)
- According to the Framingham Study, hypertension accounts for about one quarter of heart failure cases. (medscape.com)
- [ 1 ] In the elderly population, as many as 68% of heart failure cases are attributed to hypertension. (medscape.com)
- [ 2 ] Community-based studies have demonstrated that hypertension may contribute to the development of heart failure in as many as 50-60% of patients. (medscape.com)
- In patients with hypertension, the risk of heart failure is increased by two-fold in men and by three-fold in women. (medscape.com)
- Obesity has been linked to hypertension and left ventricular hypertrophy (LVH) in various epidemiologic studies, with as many as 50% of obese patients having some degree of hypertension and as many as 60-70% of patients with hypertension being obese. (medscape.com)
- Pulmonary hypertension is high blood pressure in your pulmonary arteries, which carry oxygen-poor blood from your heart to your lungs. (clevelandclinic.org)
- Pulmonary hypertension is dangerous because it disrupts the flow of blood through your heart and lungs . (clevelandclinic.org)
- Without treatment, pulmonary hypertension can overtax your heart and eventually be fatal. (clevelandclinic.org)
- These patients typically present with mild systolic dysfunction, left ventricular (LV) hypertrophy, and advanced diastolic dysfunction with pulmonary hypertension. (acc.org)
- Cardiopulmonary exercise testing helps identify exercise-induced left atrial hypertension in HCM patients. (acc.org)
- 0001). In addition, after multivariable adjustment, diabetes (OR, 1.4 for men and 1.6 for women), hypertension (OR, 1.5 for men and 1.4 for women), congestive heart failure (OR, 4.5 for men and 5.9 for women), and valve disease (OR, 1.8 for men and 3.4 for women) were significantly associated with risk for atrial fibrillation in both sexes. (nih.gov)
- The heart failure risk potentially attributed to obesity as measured by BMI or waist circumference was calculated after adjusting for multiple other health and lifestyle risk factors for heart disease, including other conditions such as Type 1 or Type 2 diabetes, hypertension (or high blood pressure), kidney function, inflammation, left ventricular hypertrophy and prior heart attack. (worldhealth.net)
- On echocardiography, the characteristic appearance includes a thickened ventricular septum and left ventricular posterior wall without an obvious etiology (eg, hypertension, aortic stenosis). (medscape.com)
- As presented at the American Heart Association's (AHA) Council on Hypertension, women who develop preeclampsia during pregnancy are more at risk for developing left ventricular thickening within one month after delivery. (galfandberger.com)
- Many dialysis patients are fluid overloaded or hypervolemic, which can lead to hypertension 1 , left ventricular hypertrophy 2 , and congestive heart failure 3 . (fmcna.com)
- The next series of articles address the genomics of hypertension, left ventricular hypertrophy, and how genomic differences may underlie the apparent racial differences in heart failure and therapeutics. (elsevier.ca)
- A clinical syndrome known as hypertension is characterised by elevated systemic arterial blood pressure (systolic blood pressure of at least 140 mmHg and diastolic blood pressure of at least 90 mmHg), which can result in damage to the kidney, heart, brain, and other organs. (alliedacademies.org)
- The aim of this study was to evaluate the efficacy of renal denervation (RDN) on cardiac function and left ventricular hypertrophy in patients diagnosed with resistant hypertension with systolic and diastolic dysfunction. (bvsalud.org)
- Conclusions: Our findings show that in addition to hypertension and its progression, elevated sympathetic hyperactivity is related to left ventricular hypertrophy and cardiac function. (bvsalud.org)
- Coarctation of the aorta is a localized narrowing of the aortic lumen that results in upper-extremity hypertension, left ventricular hypertrophy, and, if severe, malperfusion of the abdominal organs and lower extremities. (msdmanuals.com)
- Pressure overload causes left ventricular hypertrophy and hypertension in the upper part of the body, including the brain. (msdmanuals.com)
- Une recherche documentaire a été effectuée dans PubMed de 1980 à 2021 en utilisant diverses combinaisons de termes MeSH comme tabac, diabète, hypertension, dyslipidémie, trouble dépressif majeur, trouble bipolaire, schizophrénie. (bvsalud.org)
Dysfunction12
- These changes in turn can lead to the development of left ventricular hypertrophy (LVH), coronary artery disease (CAD), various conduction system diseases, and systolic and diastolic dysfunction of the myocardium, complications that manifest clinically as angina or myocardial infarction, cardiac arrhythmias (especially atrial fibrillation), and congestive heart failure (CHF). (medscape.com)
- Cardiac causes of dyspnea include right, left or biventricular congestive heart failure with resultant systolic dysfunction, coronary artery disease, recent or remote myocardial infarction, cardiomyopathy, valvular dysfunction, left ventricular hypertrophy with resultant diastolic dysfunction, asymmetric septal hypertrophy, pericarditis and arrhythmias. (aafp.org)
- The computational results simulating the effects of transmural alterations in the ventricular tissue replicate the phenotypic patterns of LV dysfunction observed in clinical practice. (frontiersin.org)
- Mild systolic dysfunction in HCM is also associated with a 10-fold greater risk for death or heart transplant in 10 years compared with HCM with preserved EF. (acc.org)
- Irreversible PH is not uncommon in these patients and can lead to ineligibility to heart transplant and also cause post-transplant right ventricular dysfunction. (acc.org)
- Oxidative stress and mitochondrial dysfunction are important mechanisms of ventricular remodeling, predisposed to the development of diabetic cardiomyopathy (DCM) in type 2 diabetes mellitus. (mdpi.com)
- A total of 2,413 participants in the Dallas Heart Study who were without clinical HF, LV dysfunction, or chronic kidney disease underwent measurement of LV mass by magnetic resonance imaging (MRI). (acc.org)
- Diagnostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) for left ventricular dysfunction in patients with chronic kidney disease stage 5 on haemodialysis. (fmcna.com)
- Arrhythmogenesis and contractile dysfunction in heart failure - Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. (4science.ge)
- Enalapril is a prescription medication used to treat high blood pressure, heart failure, and a heart condition called left ventricular dysfunction. (rxwiki.com)
- Серцева недостатність (СН) Heart failure (HF) is a syndrome of ventricular dysfunction. (msdmanuals.com)
- And then certainly critical illness and you'll hear about that by our presenters, which include respiratory failure, or ARDS, septic shock, multi-organ dysfunction and failure. (cdc.gov)
Congestive15
- As it worsens, symptoms of congestive heart failure gradually arise. (radiopaedia.org)
- Zestril is a prescription medication used to treat high blood pressure, congestive heart failure, and to improve survival after a heart attack. (rxwiki.com)
- Cardiomegaly without congestive heart failure. (acvr.org)
- Patients with severe calcific degenerative aortic stenosis can be categorized into three clinical groups at the time of diagnosis: those without evidence of congestive heart failure, those with chronic congestive heart failure, and those with acute heart failure requiring hospitalization. (medscape.com)
- In addition to intrinsic cardiac causes such as valve disease and congestive heart failure, risk factors for cardiovascular disease also predispose to atrial fibrillation. (nih.gov)
- L-carnitine supplementation also prevents the progression of heart muscle damage in people with congestive heart failure and improves exercise tolerance in people who develop chest pain (angina) with exertion. (lifeextension.com)
- To evaluate whether an increased pulse pressure could serve as a predictor of congestive heart failure in the elderly, Chae and colleagues conducted a prospective cohort study of the possible relationship between increased pulse pressure and the occurrence of congestive heart failure in 1,621 elderly persons. (aafp.org)
- None showed evidence of congestive heart failure at the time of entry into the study. (aafp.org)
- The development of congestive heart failure was the primary end point, and it was subsequently diagnosed in 221 of the participants during the 3.8 years of follow-up. (aafp.org)
- The risk of congestive heart failure was linearly and significantly related to the pulse pressure. (aafp.org)
- There was an age-adjusted 17 percent increase in the risk of congestive heart failure with every 10 mm Hg rise in the pulse presure. (aafp.org)
- Those who had the highest tertile pulse pressures had a 75 percent increased risk of congestive heart failure compared with those whose pulse pressures were in the lowest tertile. (aafp.org)
- The mean arterial pressure was not associated with an increased risk of congestive heart failure. (aafp.org)
- The authors conclude that pulse pressure is an independent predictor of the risk of congestive heart failure. (aafp.org)
- Knowing that a patient is at increased risk of congestive heart failure is important because the risk may be modified by drug therapy with angiotensinconverting enzyme inhibitors, which may cause left ventricular hypertrophy regression, and nitrates, which may improve arterial distensibility, and by other therapeutic interventions, such as a low-salt diet. (aafp.org)
Cause left ventricular1
- A large number of conditions can cause left ventricular hypertrophy. (radiopaedia.org)
Concentric hypertrophy7
- Conversely, concentric hypertrophy can make itself known in a variety of ways. (wikipedia.org)
- Ventricular hypertrophy may be divided into two categories: concentric hypertrophy and eccentric hypertrophy. (wikipedia.org)
- Concentric hypertrophy is a result of pressure overload on the heart, resulting in parallel sarcomerogenesis (addition of sarcomere units parallel to existing units). (wikipedia.org)
- Concentric hypertrophy is characterized by an addition of sarcomeres (the contractile units of cardiac cells) in parallel. (wikipedia.org)
- Further stratification of both the normal and hypertrophic left ventricle then proceeds using relative wall thickness, which subdivide the former into normal ventricles and those with concentric remodeling, and the latter into eccentric and concentric hypertrophy 3 . (radiopaedia.org)
- Concentric hypertrophy and concentric remodeling are the most common geometric patterns. (bvsalud.org)
- Concentric hypertrophy was defined as elevated RWT and LVmi, eccentric hypertrophy defined by elevated LVmi with normal RWT and concentric remodelling defined as elevated RWT with normal LVmi, per 2015 American Society of Echocardiography guidelines. (cdc.gov)
Myocardial hypertrophy3
- In summary, Res treatment effectively suppressed myocardial hypertrophy and apoptosis at least partially via inhibiting ER stress. (karger.com)
- The mentioned study can be considered another step forward in the study of the pathogenetic mechanisms of myocardial hypertrophy and remodeling. (4science.ge)
- [ 4 ] The excessive intrasarcomeric glycogen is mostly responsible for the severe myocardial hypertrophy and is possibly responsible for pre-excitation. (medscape.com)
Measuring left ventricular mass1
- Currently, cMRI is considered to gold standard for measuring left ventricular mass, although expensive. (acc.org)
Hypertrophic cardiomyopathy1
- A hypertrophic cardiomyopathy characterized by apical hypertrophy, typically LEFT VENTRICULAR HYPERTROPHY (described as "ace of spades" sign), and deep T-wave inversions in EKG. (bvsalud.org)
Arrhythmias3
- Thus, hypertensive heart disease is a term applied generally to heart diseases, such as LVH (seen in the images below), coronary artery disease, cardiac arrhythmias, and CHF, that are caused by the direct or indirect effects of elevated BP. (medscape.com)
- Patients with Danon disease require frequent follow-up, with particular attention to the potential for atrial or ventricular arrhythmias and CHF. (medscape.com)
- Fatal or life-threatening cardiomyopathy and ventricular arrhythmias were reported. (nih.gov)
Tetralogy of Fal3
- Tetralogy of Fallot is a type of congenital heart defect. (medlineplus.gov)
- Tetralogy of Fallot is rare, but it is the most common form of cyanotic congenital heart disease. (medlineplus.gov)
- Children with tetralogy of Fallot are more likely to have chromosome disorders, such as Down syndrome, Alagille syndrome, and DiGeorge syndrome (a condition that causes heart defects, low calcium levels, and poor immune function). (medlineplus.gov)
Asymptomatic3
- When mild, left ventricular hypertrophy is usually asymptomatic. (radiopaedia.org)
- May be asymptomatic for many years (or for life) or may cause left-sided heart failure. (health.am)
- In this study, the authors tested the ability of markers of subclinical myocardial injury (high sensitivity cardiac troponin T [hscTnT]) and hemodynamic stress (N-terminal pro-B-type natriuretic peptide [NT-proBNP]) for identifying asymptomatic individuals with LVH who were at increased risk for heart failure (HF) and death. (acc.org)
Ejection fraction3
- The pathophysiological mechanisms underlying preserved left ventricular (LV) ejection fraction (EF) in patients with heart failure and preserved ejection fraction (HFpEF) remain incompletely understood. (frontiersin.org)
- We hypothesized the existence of distinct phenotype-based groups within the very heterogeneous population of patients of heart failure with preserved ejection fraction (HFpEF) and using an unsupervised hierarchical clustering applied to plasma concentration of various biomarkers. (karger.com)
- Clinical predictors of AHF in HCM include atrial fibrillation, family history of AHF-HCM with reduced ejection fraction (EF), treated ventricular arrhythmia, and septal myectomy. (acc.org)
Regression1
- Accordingly, LVAD should be considered only in subgroups of HCM-AHF patients with LV hypertrophy regression and LV enlargement. (acc.org)
Atherosclerosis1
- It was observed that many of the risk factors for cardiovascular diseases begin in childhood, including high blood pressure, which can lead to coronary atherosclerosis and left ventricular hypertrophy 10 . (bvsalud.org)
Right ventricular3
- better source needed] Although left ventricular hypertrophy (LVH) is more common, right ventricular hypertrophy (RVH), as well as concurrent hypertrophy of both ventricles can also occur. (wikipedia.org)
- This condition (right ventricular hypertrophy) can lead to right-sided heart failure . (clevelandclinic.org)
- Left ventricular (LV) failure causes shortness of breath and fatigue, and right ventricular (RV) failure causes peripheral and abdominal. (msdmanuals.com)
Valvular heart d6
- He is a PhD supervisor and researcher in the field of coronary calcification, and Doppler echocardiography in heart failure and valvular heart disease. (umu.se)
- Currently the most active projects Michael Henein's Team is working on are coronary calcification, heart failure and valvular heart disease. (umu.se)
- Women were significantly more likely than men to have valvular heart disease as a risk factor for atrial fibrillation. (nih.gov)
- The multivariable models were largely unchanged after eliminating subjects with valvular heart disease. (nih.gov)
- Diabetes was present at baseline in 19.3 percent, coronary heart disease in 10.3 percent, atrial fibrillation in 2.8 percent and valvular heart disease in 1.8 percent. (aafp.org)
- Page 2 fibrillation or flutter, previous myocardial infarction, rheumatic valvular heart disease and Author Manuscript prosthetic heart valve) and psychosocial stress/depression [3]. (cdc.gov)
Septal defect1
- Corrective surgery is done to widen part of the narrowed pulmonary tract and close the ventricular septal defect with a patch. (medlineplus.gov)
Cardiomegaly1
- Additional autopsy findings included coronary artery disease, cardiomegaly (enlarged heart), and left ventricular hypertrophy (LVH). (cdc.gov)
Ventricle9
- Ventricular hypertrophy (VH) is thickening of the walls of a ventricle (lower chamber) of the heart. (wikipedia.org)
- citation needed] The ventricles are the chambers in the heart responsible for pumping blood either to the lungs (right ventricle) or to the rest of the body (left ventricle). (wikipedia.org)
- as a result the right ventricle undergoes hypertrophy to compensate for these increased pressures. (wikipedia.org)
- However, this type of hypertrophy can result in a dilated ventricle which is unable to effectively pump blood, leading to heart failure. (wikipedia.org)
- The net effect is an increased volume load on the left ventricle, and the presentation depends on the rapidity with which the lesion develops. (health.am)
- The aim of the study was to assess the quality of hyperthrophy of the left ventricle in 10-11 week-old rats after a 6-week dosed swimming load. (4science.ge)
- In general, rat swimming is considered one of the best physiological triggers for hypertrophy of the left ventricle and end-diastolic volume increase. (4science.ge)
- The increase in the mass of the heart was mainly due to an increase in the mass of the left ventricle. (4science.ge)
- The left ventricular assist device (LVAD), approved by the FDA, is a system comprised of an implanted pump and an external battery-powered pump controller designed to work in unison with the patient's weakened left ventricle to provide additional blood flow. (unboundmedicine.com)
Coronary Heart D6
- For patient education information, see the Heart Health Center , Diabetes Center and the Cholesterol Center , as well as High Blood Pressure , High Cholesterol , Chest Pain , Coronary Heart Disease , and Heart Attack . (medscape.com)
- Conduct exercise stress tests into the fire department medical evaluation program for fire fighters at increased risk for coronary heart disease (CHD). (cdc.gov)
- By 2005, the total number of cardiovascular disease (CVD) deaths (mainly coronary heart disease, stroke, and rheumatic heart disease) had increased globally to 17.5 million from 14.4 million in 1990. (health.am)
- Of these, 7.6 million were attributed to coronary heart disease and 5.7 million to stroke. (health.am)
- Gender, the presence of coronary heart disease or atrial fibrillation, and smoking history were not related to an increased pulse pressure. (aafp.org)
- 5) Behavior Questionnaire elicited data on behavior which may be associated with coronary heart disease for examined persons ages 25-74. (cdc.gov)
Obesity7
- The relationship between obesity and left ventricular hypertrophy is complex. (radiopaedia.org)
- Electrocardiographic left ventricular hypertrophy , obesity and incident cardiovascular events. (escardio.org)
- While women who enter menopause before age 45 are known to be at higher risk of heart failure, obesity significantly increased heart failure risk among women who experienced late menopause - at age 55 or older, according to a new study. (worldhealth.net)
- The findings indicate that maintaining a healthy weight and avoiding abdominal obesity may protect against developing heart failure, especially among women who experience late menopause. (worldhealth.net)
- While women who enter menopause before age 45 are known to be at higher risk for heart failure, obesity significantly increased heart failure risk among women who experienced late menopause -- at age 55 or older, according to new research published today in the Journal of the American Heart Association , an open access, peer-reviewed journal of the American Heart Association. (worldhealth.net)
- We know that obesity increases the risk of developing heart failure, and the onset of menopause is associated with increased body fatness," said Ebong. (worldhealth.net)
- In our study, we investigated if and how obesity affects the relationship between menopausal age and the future risk of developing heart failure. (worldhealth.net)
Overload4
- Eccentric hypertrophy is related to volume overload and leads to the addition of sarcomeres in series. (wikipedia.org)
- It is a response to 'volume-overload', either as a result of increased blood return to the heart during exercise, or a response to an actual increase in absolute blood volume as in pregnancy. (wikipedia.org)
- Hemodynamically, left ventricular volume overload may ultimately lead to left ventricular failure and reduced cardiac output, but for many years the left ventricular end- diastolic pressure and the cardiac output may be normal at rest, even with considerable increase in left ventricular volume. (health.am)
- Cardiac hypertrophy primarily happens when the myocardium's total volume is increased and its contractility is strengthened due to prolonged myocardial pressure overload. (alliedacademies.org)
Hypertensive patients1
- BACKGROUND: This study aimed to assess the relationship of a new anthropometric index with left ventricular hypertrophy (LVH) in hypertensive patients among the Han Chinese. (bvsalud.org)
Eccentric3
- In individuals with eccentric hypertrophy there may be little or no indication that hypertrophy has occurred as it is generally a healthy response to increased demands on the heart. (wikipedia.org)
- Eccentric hypertrophy is generally regarded as healthy, or physiologic hypertrophy and is often termed "athlete's heart. (wikipedia.org)
- Eccentric left ventricular hypertrophy and left atrial enlargement. (acvr.org)
Atrial enlargement2
- Two-dimensional echocardiogram (parasternal long axis view) from a 70-year-old woman showing concentric left ventricular hypertrophy and left atrial enlargement. (medscape.com)
- Mitral regurgitation leads to left atrial enlargement and may cause subsequent atrial fibrillation. (health.am)
Wall thickness2
- Rowers, cyclists, and cross-country skiers tend to have the largest hearts, with an average left ventricular wall thickness of 1.3 centimeters, compared to 1.1 centimeters in average adults. (wikipedia.org)
- LVMI and relative wall thickness were used to determine left ventricular geometry. (bvsalud.org)
Severe myocardial1
- Advanced patients' disease is characterised by severe myocardial fibrosis and impaired ventricular systolic function [ 3 ]. (alliedacademies.org)
Cardiomyopathy2
- Given the LT's underlying dilated cardiomyopathy, the physical stress of responding to the call and climbing the embankment may have triggered a fatal heart arrhythmia. (cdc.gov)
- A transient left ventricular apical hypertrophy is sometimes associated with TAKOTSUBO CARDIOMYOPATHY. (bvsalud.org)
Pathology1
- See also Aortic Stenosis , Pediatric Valvar Aortic Stenosis , Pediatric Rheumatic Heart Disease , and Pathology of Rheumatic Heart Disease . (medscape.com)
Symptoms4
- For patients with New York Heart Association class III/IV symptoms with normal resting hemodynamics, exercise testing can be useful. (acc.org)
- Dyspnea, exhaustion, a decreased capacity for exercise, syncope, angina pectoris, chest pain, and right heart failure are among the symptoms of the disease as it progresses [ 1 ]. (alliedacademies.org)
- Heart failure and palpitations are two of the main signs and symptoms of cardiac hypertrophy, along with dyspnea, chest pain, exhaustion, wooziness and fainting. (alliedacademies.org)
- Symptoms vary with the anomaly's severity and range from headache, chest pain, cold extremities, fatigue, and leg claudication to fulminant heart failure and shock. (msdmanuals.com)
Etiology1
- The etiology of hypertensive heart disease is a complex interplay of various hemodynamic, structural, neuroendocrine, cellular, and molecular factors. (medscape.com)
Shortness of bre1
- Overt signs of heart failure, such as edema, or shortness of breath without exertion are uncommon. (wikipedia.org)
Echocardiography3
- Echocardiography, cardiac MRI and cardiac CT are the main modalities for evaluating for left ventricular hypertrophy. (radiopaedia.org)
- Robust reference data exists for quantifying left ventricular size with echocardiography, using guidelines from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. (radiopaedia.org)
- Left ventricular mass was measured by echocardiography. (bvsalud.org)
Mortality5
- Background--As heart failure (HF)-associated morbidity and mortality continue to escalate, enhanced focus on prevention is increasingly important. (johnshopkins.edu)
- Heart Failure (HF) is the only cardiovascular disease for which incidence, prevalence, morbidity, mortality, and costs are not decreasing. (frontiersin.org)
- Mortality, Hospitalization, and Technique Failure in Daily Home Hemodialysis and Matched Peritoneal Dialysis Patients: A Matched Cohort Study. (slideshare.net)
- Among birth defects, congenital heart disease is the leading cause of infant mortality. (msdmanuals.com)
- Cadmium exposure has been associated with increased risk of stroke, heart failure, and cardiovascular mortality. (cdc.gov)
Prevalence1
- BACKGROUND: To investigate the prevalence of left ventricular hypertrophy (LVH) and explore left ventricular geometry in maintenance hemodialysis (MHD) patients, and to explore the risk factors of LVH which is an important predictor of cardiovascular events. (bvsalud.org)
Geometry2
- State of the art in left ventricular geometry. (escardio.org)
- Exposure to heavy metals linked to increased left ventricular mass and abnormal geometry. (cdc.gov)
Cardiomyocytes1
- Res effectively suppress the cardiomyocytes hypertrophy and apoptosis induced by ISO, characterized by the reduction of the myocardial cell surface area, the ANP gene expression, the LDH and MDA leakage amount and the rate of cell apoptosis, while decrease of the protein expression of GRP78, GRP94 and CHOP, and reverse the expression of Bcl-2 and Bax. (karger.com)
Typically1
- Although the cardiac hypertrophy is an adaptive response of the heart that responds to a variety of extrinsic and intrinsic stimuli, prolonged hypertrophy typically culminates in chronic heart failure or sudden cardiac death. (karger.com)
Blood vessels3
- Zestril belongs to a group of drugs called angiotensin converting enzyme (ACE) inhibitors, which relax blood vessels to lower blood pressure and make the heart pump more efficiently. (rxwiki.com)
- These are the blood vessels that carry oxygen-poor blood from your heart to your lungs. (clevelandclinic.org)
- The most clinically significant sites of accumulation of Gb3 are blood vessels of the skin, heart, nerves , and kidneys [8]. (dermnetnz.org)
Fibrillation1
- In acute mitral regurgitation, patients are in sinus rhythm rather than atrial fibrillation and have little or no enlargement of the left atrium, no calcification of the mitral valve, no associated mitral stenosis , and in many cases little left ventricular dilation. (health.am)
Chronic2
- When it is chronic, the left atrium enlarges progressively, but the pressure in pulmonary veins and capillaries rises only transiently during exertion. (health.am)
- Soluble ST-2 is another prognostic biomarker measured in blood samples, used to predict increased risk for progression of HF-elevations in patients identified with chronic heart failure predict elevated risk of disease progression ST-2 is an interleukin family receptor secreted by cardiac muscle in response to mechanical stress. (unboundmedicine.com)
Acute3
- The prognosis is especially poor in the setting of acute heart failure, for which aortic valve replacement provides the least benefit. (medscape.com)
- In acute regurgitation, left atrial pressure rises abruptly, leading to pulmonary edema if severe. (health.am)
- Eur Heart J Acute Cardiovasc Care. (ucsd.edu)
Findings3
- Findings showed that higher serum sodium concentration in midlife was associated with both heart failure and left ventricular hypertrophy 25 years later. (express.co.uk)
- In addition, our findings showed that serum sodium exceeding 142 mmol/l increases the risk of adverse effects in the heart and may help to identify people who could benefit from an evaluation of their hydration level. (express.co.uk)
- According to Duke team leader Lana Watkins, Ph.D., the researchers believe their findings add further support for the potential role oft non-pharmocological approaches to treating depression, such as exercise, in reducing the risk of death in depressed heart patients. (sciencedaily.com)
Stroke1
- Serious and potentially life-threatening complications including kidney damage, heart disease, and stroke [11]. (dermnetnz.org)
Malignant1
- Malignant" left ventricular (LV) hypertrophy (LVH): LVH combined with an elevated cardiac biomarker reflecting either injury (high-sensitivity cardiac troponin T), or strain (amino-terminal pro-B-type natriuretic peptide) has predicted accelerated progression to HF. (johnshopkins.edu)
Cardiovascular diseases1
- During the pathological development of cardiovascular diseases, cardiac hypertrophy plays a critical role. (karger.com)
Acutely decompensated heart failure1
- The impact of sleep disordered breathing on cardiac troponin in acutely decompensated heart failure. (ucsd.edu)
LVMI1
- LVH was diagnosed by using the criteria of left ventricular mass indexed (LVMI) over 49.2 g/m2.7 for men and 46.7 g/m2.7 for women. (bvsalud.org)
Patients12
- Up to 1 in 15 patients with HCM progress to advanced heart failure (AHF). (acc.org)
- Right heart catheterization in HCM patients with AHF is notable for severely increased pulmonary capillary wedge pressures with a decreased cardiac output. (acc.org)
- Even after controlling for such factors as age, degree of heart disease and severity of depression, the researchers found that heart patients taking antidepressant medications had a 55 percent higher risk of dying. (sciencedaily.com)
- Previously, Duke researchers reported that the presence of depression is an important risk factor for heart patients. (sciencedaily.com)
- She said that physicians caring for heart patients who are taking antidepressants should monitor patients closely. (sciencedaily.com)
- After adjusting for such factors as age, gender, heart pumping strength, smoking history, degree of other illnesses, heart procedures, BDI score and education, the researchers found that patients taking antidepressants had a 55 percent higher risk of dying. (sciencedaily.com)
- Patients taking carnitine had a death rate of just 1.2% in the entire year, while 12.5% of control patients died, with the majority of deaths attributed to repeat heart attacks. (lifeextension.com)
- What is the independent contribution of elevated biomarkers to predicting risk in patients with left ventricular hypertrophy (LVH)? (acc.org)
- Until 2017, patients with advanced HF had few alternatives to extend their lives if a heart transplant was not a timely option. (unboundmedicine.com)
- Assist in determining the prognosis and therapy of patients with heart failure. (unboundmedicine.com)
- Patients who experienced arrhythmia during HD had higher left ventricular mass and left ventricular mass index, lower post-dialysis K+ level, higher QTc and QTdc both before and after HD. (who.int)
- The study sample was drawn from patients nant ventricular tachyarrhythmia [ 2 ]. (who.int)
Systole2
- During left ventricular systole, the mitral leaflets do not close normally, and blood is ejected into the left atrium as well as through the aortic valve. (health.am)
- The first is the systole , when the heart contracts and ejects blood into the arteries. (withings.com)
Significantly3
- Multiple randomized clinical trials show intensive hemodialysis significantly reduces left ventricular mass and more frequent hemodialysis has associated with lower risk of cardiovascular-related hospitalizations. (slideshare.net)
- Multiple randomized clinical trials show intensive hemodialysis significantly reduces left ventricular mass.1,2,3 1FHN Trial Group, Chertow GM, Levin NW, et al. (slideshare.net)
- ST-segment depression was significantly related to ventricular arrhythmia. (who.int)
Disease12
- Given the D/O's underlying heart disease, NIOSH investigators concluded that the physical stress of responding to the call and ascending/descending the aerial ladder to the roof of a three-story building probably triggered his sudden cardiac death. (cdc.gov)
- The most common causes are heart disease, lung disease and hypoxia. (clevelandclinic.org)
- It's usually a complication of heart disease or lung disease. (clevelandclinic.org)
- I'm Dr Rajiv Gulati, a cardiologist at Mayo Clinic in Rochester, Minnesota, and today I'm joined by Dr Allan Jaffe, who is a well-known expert in the field of biomarkers and heart disease. (medscape.com)
- Only cancer and heart disease claim more lives annually. (galfandberger.com)
- Use Panax ginseng with caution if you have heart disease. (webmd.com)
- CAD and MI are the most common causes of heart disease and most common causes of HF. (unboundmedicine.com)
- Other conditions that can contribute to the development or acceleration of HF include anemia, congenital heart defect, diabetes, kidney disease, and thyroid disease. (unboundmedicine.com)
- Assist in differentiating heart failure from pulmonary disease. (unboundmedicine.com)
- Огляд вроджених серцево-судинних аномалій Congenital heart disease is the most common congenital anomaly, occurring in almost 1% of live births ( 1). (msdmanuals.com)
- Bernstein D. Cyanotic congenital heart disease: evaluation of the critically ill neonate with cyanosis and respiratory distress. (medlineplus.gov)
- Congenital heart disease in the adolescent and adult. (medlineplus.gov)
Cardiac MRI1
- Cardiac MRI (CMR) is the current gold standard for evaluation of left ventricular hypertrophy, with the ability to measure multiple other myocardial parameters simultaneously. (radiopaedia.org)