• As mitral regurgitation (MR) becomes severe, the continued hemodynamic burden may lead to ventricular dysfunction, heart failure, and sudden death. (medscape.com)
  • Dependent edema and pulmonary rales are of limited value in diagnosing heart failure resulting from left ventricular dysfunction. (aafp.org)
  • OBJECTIVES: This study aimed to explore the impact of myocardial bridging (MB) on early development of cardiac allograft vasculopathy and long-term graft survival after heart transplantation.BACKGROUND: MB has been reported to be associated with acceleration of proximal plaque development and endothelial dysfunction in native coronary atherosclerosis. (stanford.edu)
  • Tricuspid atresia is the most common cause of cyanosis with left ventricular hypertrophy. (medscape.com)
  • 3 Heart failure is becoming increasingly common as the U.S. population ages and survival rates after acute myocardial infarction increase. (aafp.org)
  • Female gender (P = 0.002), pre-operative myocardial infarction (P = 0.02), significant diagonal disease (P = 0.04) and postoperative myocardial infarction (P = 0.0001) were independently associated with survival. (bvsalud.org)
  • Radionuclide angiography or contrast cineangiography may be necessary when clinical suspicion for heart failure is high and the echocardiogram is equivocal. (aafp.org)
  • Mismatched perfusion defects on lung ventilation/perfusion (V/Q) scan and specific diagnostic signs for CTEPH seen by multidetector computed tomography angiography (MDCT), magnetic resonance imaging (MRI) or conventional pulmonary cineangiography (PAG), such as ring-like stenoses, webs/slits, chronic total occlusions (pouch lesions, or tapered lesions) and tortuous lesions. (wikipedia.org)
  • The recommended diagnostic algorithm stresses the importance of initial investigation using an echocardiogram and V/Q scan and confirmation with right heart catheter and pulmonary angiography (PA). (wikipedia.org)
  • Significant coronary artery disease was defined as a >50% luminal diameter stenosis on coronary angiography. (bvsalud.org)
  • UNLABELLED: In this prospective study, patients referred for coronary angiography for detection of disease underwent dobutamine stress echocardiography to define its value in a clinical practice setting. (bvsalud.org)
  • The presence of heart failure can be confirmed by an echocardiogram. (aafp.org)
  • 1. We will get an echocardiogram for assessment left ventricular function. (mtsamples.com)
  • The evaluation of symptomatic patients with suspected heart failure is directed at confirming the diagnosis, determining the cause, identifying concomitant illnesses, establishing the severity of heart failure, and guiding therapy. (aafp.org)
  • Absence of dyspnea or a normal ECG and chest radiograph make the diagnosis of heart failure highly unlikely. (aafp.org)
  • This article focuses on the diagnosis of heart failure from an evidence-based perspective. (aafp.org)
  • Mitral regurgitation is the most common type of moderate or severe heart valve disease in adults older than 55 years. (medscape.com)
  • Mitral regurgitation as seen with left ventricular (LV) cineangiography. (medscape.com)
  • Chronic severe mitral regurgitation is commonly caused by myxomatous degeneration of the valve, rheumatic heart disease, or mitral annular calcification. (medscape.com)
  • Although the heart may not be enlarged in patients with acute mitral regurgitation, severe pulmonary edema is frequently present as a result of left-sided cardiac failure. (medscape.com)
  • The capacity of the heart to adapt to short-term changes in preload or afterload is remarkable, but sudden or sustained changes in preload (e.g., acute mitral regurgitation, excessive intravenous hydration), afterload (e.g., aortic stenosis, severe uncontrolled hypertension), or demand (e.g., increased demand because of severe anemia or hyperthyroidism) may lead to progressive failure of myocardial function. (aafp.org)
  • Coronary artery disease is its most common cause. (aafp.org)
  • Patients with coronary artery disease, hypertension, diabetes mellitus, exposure to cardiotoxic drugs, alcohol abuse, or a family history of cardiomyopathy are at high risk for heart failure and may benefit from routine screening. (aafp.org)
  • The procedure is done via femoral, subclavian, radial, or brachial artery puncture, with a catheter passed into the coronary artery ostia and/or across the aortic valve into the left ventricle (LV). (msdmanuals.com)
  • CTPA alone cannot exclude the disease, but may help identify pulmonary artery distension resulting in left main coronary artery compression, pulmonary parenchymal lesions (e.g. as complications from previous pulmonary infarctions), and bleeding from bronchial collateral arteries. (wikipedia.org)
  • PURPOSE: We assessed the value of dobutamine stress echocardiography for the detection of coronary artery disease in patients with chest pain and an abnormal resting electrocardiograph (ECG). (bvsalud.org)
  • RESULTS: The sensitivity, specificity, positive and negative predictive value of dobutamine stress echocardiography for the detection of coronary artery disease in 218 patients were 89, 50, 95 and 32%, respectively. (bvsalud.org)
  • CONCLUSION: Dobutamine stress echocardiography is better than exercise ECG for the detection of significant coronary artery disease. (bvsalud.org)
  • AIMS: To detail the clinical and angiographic profile, and long-term outcome in consecutive patients with isolated stenosis of the left anterior descending coronary artery undergoing bypass surgery. (bvsalud.org)
  • METHODS: A retrospective study of all patients (n = 301) (January 1984-December 1990) and undergoing coronary artery bypass grafting for isolated left anterior descending disease, in the Irish Republic, was performed. (bvsalud.org)
  • CONCLUSIONS: Survivorship (97%) and event-free survival (96%) at 5 years following coronary artery bypass grafting for isolated left anterior descending coronary artery disease is excellent and equivalent to an age-matched and gender-matched cohort. (bvsalud.org)
  • Primary intracoronary stenting of a calcified left anterior descending coronary artery stenosis was complicated by within-stent coronary artery rupture and subsequent cardiac tamponade. (bvsalud.org)
  • RESULTS: Of 219 patients studied, 170 (78%) had significant coronary artery disease. (bvsalud.org)
  • The overall sensitivity and specificity of dobutamine stress echocardiography for coronary artery disease were 82 and 65%, respectively. (bvsalud.org)
  • Positive and negative predictive values for coronary artery disease were 89 and 51%, respectively. (bvsalud.org)
  • Dobutamine stress echocardiography correctly identified only 72 of 138 patients with significant stenosis of the left anterior descending coronary artery. (bvsalud.org)
  • Impact of myocardial bridging on coronary artery plaque formation and long-term mortality after heart transplantation. (stanford.edu)
  • No history of established coronary artery disease and family history noncontributory for coronary disease. (mtsamples.com)
  • A suspicion of PH is often raised by echocardiography, but an invasive right heart catheterisation is required to confirm it. (wikipedia.org)
  • The most frequent indications for right heart catheterization are to assess hemodynamics, diagnose pulmonary hypertension, guide therapy, and assess need for cardiac transplantation or mechanical cardiac support (eg, a ventricular assist device). (msdmanuals.com)
  • Right heart catheterization is also useful for assessing cardiac filling pressures, pulmonary vascular resistance, tricuspid or pulmonic valve function, intracardiac shunts, and right ventricular pressure. (msdmanuals.com)
  • Chronic thromboembolic pulmonary hypertension (CTEPH) is a long-term disease caused by a blockage in the blood vessels that deliver blood from the heart to the lungs (the pulmonary arterial tree). (wikipedia.org)
  • The blockages either result from organised (or hardened) blood clots that usually originate from the deep veins of the lower limbs of the body (thromboembolism) and lodge in the pulmonary arterial tree after passing through the right side of the heart. (wikipedia.org)
  • Some patients may present with normal or near-normal pulmonary pressures at rest despite symptomatic disease. (wikipedia.org)
  • The left ventricle (LV) must pump additional volume to compensate for the amount regurgitated. (medscape.com)
  • Little more than 3 decades ago, the terminology for this defect (eg, tricuspid atresia, univentricular heart, univentricular atrioventricular connection) was intensely debated. (medscape.com)
  • The anterior and posterior tricuspid valve leaflets develop by undermining of a skirt of ventricular muscle tissue. (medscape.com)
  • The sensitivity for detection of multi-, double- and single vessel disease were 97, 82 and 81%, respectively. (bvsalud.org)
  • The sensitivity was 88% for detection of triple-vessel disease, 83% for double-vessel disease, and 74% for single-vessel disease. (bvsalud.org)
  • These patients are labelled as having chronic thromboembolic disease (CTED). (wikipedia.org)
  • Risk factors for CTEPH include splenectomy, inflammatory bowel disease, chronic thyroid hormone replacement, blood types other than 0, malignancy, infected ventriculo-atrial shunt and permanent intravenous leads. (wikipedia.org)
  • Heart valves permit forward flow of blood through the cardiac chambers when open and prevent backward leakage when closed. (medscape.com)
  • Heart failure is highly unlikely in the absence of dyspnea and an abnormal chest radiograph or electrocardiogram. (aafp.org)
  • Heart failure can be ruled in if jugular venous distention, displacement of the apical pulsation, or a gallop rhythm is present. (aafp.org)
  • Heart failure is a common, progressive, complex clinical syndrome with high morbidity and mortality. (aafp.org)
  • A clinical review 6 published in this issue examines the treatment of heart failure and the prognosis for affected patients. (aafp.org)
  • Clinical symptoms and signs are often non-specific or absent in early CTEPH, with signs of right heart failure only in advanced disease. (wikipedia.org)
  • However, its clinical significance in heart transplantation remains unclear.METHODS: In 103 heart-transplant recipients, serial (baseline and 1-year post-transplant) volumetric intravascular ultrasound (IVUS) analyses were performed in the first 50 mm of the left anterior descending (LAD) artery. (stanford.edu)
  • Heart failure is characterized by an inability of the myocardium to deliver sufficient oxygenated blood to meet the needs of tissues and organs during exercise or at rest. (aafp.org)
  • Heart failure is estimated to affect 2 to 4.5 million persons in the United States. (aafp.org)
  • Screening the general population for heart failure is not recommended, but screening high-risk patients may be appropriate. (aafp.org)
  • The initial evaluation of patients with suspected heart failure should include a focused history and physical examination, an ECG, and a chest radiograph. (aafp.org)
  • The annual direct medical cost of caring for patients with heart failure is estimated to exceed $10 billion. (aafp.org)
  • 4 Furthermore, heart failure is a progressive condition: once symptoms appear, subsequent morbidity and mortality are high. (aafp.org)
  • In patients with heart failure identified by careful screening, five-year survival rates are only 59 percent in men and 45 percent in women. (aafp.org)
  • Patients typically have hypotension, muffled heart tones, and distended. (msdmanuals.com)
  • In 219 patients, 345 of 657 major epicardial vessels had significant disease. (bvsalud.org)
  • Triple-vessel disease was present in 65 patients. (bvsalud.org)
  • In multivariate analysis, the presence of MB was independently associated with late adverse events [hazard ratio 5.1 (1.6-22.2)].CONCLUSION: MB appears to relate to accelerated proximal intimal growth and reduced long-term survival in heart-transplant recipients. (stanford.edu)
  • and limited resistance to the flow of blood out of the heart (afterload). (aafp.org)
  • Once PH is diagnosed, the presence of thromboembolic disease requires imaging. (wikipedia.org)
  • Maseri A. Ischemic Heart Disease, 1995. (med24info.com)
  • Virmani R., Forman M.B. Nonatherosclerotic Ischemic Heart Disease, 1988. (med24info.com)
  • Patient has longstanding history of ischemic heart disease, end-stage LV systolic dysfunction, and is status post ICD implantation. (mtsamples.com)
  • PAOP approximates left atrial and left ventricular end-diastolic pressure. (msdmanuals.com)
  • Risk factors for CTEPH include splenectomy, inflammatory bowel disease, chronic thyroid hormone replacement, blood types other than 0, malignancy, infected ventriculo-atrial shunt and permanent intravenous leads. (wikipedia.org)
  • In a study by Merlo et al of 414 patients with dilated cardiomyopathy who underwent ECG testing, 55 patients experienced death or heart transplant and 57 patients experienced sudden death or malignant ventricular arrhythmias during a 125-month follow-up period. (medscape.com)
  • Dilated cardiomyopathy is associated with a large number of systemic or cardiac diseases, including specific heart muscle diseases (eg, ischemic cardiomyopathy, diabetic cardiomyopathy, alcoholic cardiomyopathy ). (medscape.com)
  • and systemic endocrine or autoimmune diseases. (medscape.com)
  • Part II: association with cardiovascular risk factors and diseases. (med24info.com)
  • As you will see, it confirms the evidence in previous reports that cigarette smoking is a serious health hazard and broadens our understanding of the mechanisms by which smoking contributes to the development of various forms of cancer, cardiovascular disease, and respiratory disease. (nih.gov)
  • The current report is devoted to recent research that enlarges the evidence on which our knowledge is based and broadens our understanding of the mechanisms whereby smoking contributes to the develop- ment of various forms of cancer, cardiovascular disease, and respiratory disease. (nih.gov)
  • Cardiovascular Disease ------------------- Chapter 2. (nih.gov)
  • CARDIOVASCULAR: PMI felt in fifth left intercostal space 0.5-inch lateral to midclavicular line. (mtsamples.com)
  • The main symptom of CTEPH is exertional breathlessness (shortness of breath during exertion such as exercise), which is unspecific and may often be attributed to other, more common, diseases by physicians. (wikipedia.org)
  • His exercise tolerance is about two to three yards for shortness of breath. (mtsamples.com)
  • 1. Atherosclerotic coronary vascular disease with old myocardial infarction. (mtsamples.com)
  • In most cases, dilated cardiomyopathy is progressive, leading to heart failure and death. (medscape.com)
  • If these reductions continue we can look forward to the time when the rapid increase of diseases associated with smoking will halt and begin a decline that will result in fewer deaths during the most productive years of life. (nih.gov)
  • Vanhoutte P.M. Endothelial control of vasomotor function: from health to coronary disease // Circ. (med24info.com)
  • Chilian W.M. Coronary microcirculation in health and disease. (med24info.com)
  • Sincerely, Caspar W. Weinberger Secretary For sale by the Superintendent of Documents, U.S. Government Printing Office, Washington, D.C. 20402 - Price $1.60 Stock Number 1723-00087 PREFACE This report is the eighth in a series issued by the Public Health Service reviewing and assessing the scientific evidence linking cigarette smoking to disease and premature death. (nih.gov)
  • Non-neoplastic Bronchopulmonary Diseases - - Page ili vii 35 71 119 PREPARATION OF THE REPORT AND ACKNOWLEDGMENTS Previous Reports "Smoking and Health. (nih.gov)
  • The evidence is clear that people who have stopped smoking cigarettes have lower death rates from smoking-related diseases than those who continue to smoke. (nih.gov)