AnatomyDiseasesAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesNamed Groups
Heart-Lung TransplantationLung TransplantationBronchiolitis ObliteransHeartLungLiver TransplantationTransplantation, HomologousPrimary Graft DysfunctionHeart TransplantationGraft RejectionKidney TransplantationLung DiseasesHeart RateBone Marrow TransplantationGraft SurvivalHematopoietic Stem Cell TransplantationTissue DonorsTransplantation, Autologous
RecipientsLiving-donorExtracorporeal membrane oxCystic2022Advanced Lung DiseaseJournal of Heart and Lung TransplantationKidneyOutcomesDiseaseField of lung transplantationPediatricCongenitalSurvivalISHLTOrgan transplantationsDetection of allograft dysfunction2016BilateralDiseasesInfectionRejectionComplicationsMortality1988ChronicDouble lungDonation and TransplantationDonorsSurgerySurgicalRenalOrgansPulmonary hypertensionIschemia-reperfusion injuryEmphysema2017BronchoscopyCardiacSurgeonsUnderwent1983Single Lung TransplantProceduresComputed tomographyRespiratoryMicrobiomeTissuesTransplant is donePost-transplant1963
Recipients23
  • Whether the alternated microbiota in the gut contribute to the risk of allograft rejection (AR) and pulmonary infection (PI) in the setting of lung transplant recipients (LTRs) remains unexplored. (nature.com)
  • This article is meant not only to serve as an overview of the field of lung transplantation but also to highlight the unique challenges faced by pediatric lung transplant recipients, their families, and their healthcare teams. (medscape.com)
  • Many lung transplant physicians advocate surveillance bronchoscopy with transbronchial lung biopsy and bronchoalveolar lavage (TBB/BAL) to monitor lung recipients despite limited evidence this strategy improves outcomes. (nih.gov)
  • This report compares rates of infection (INF), acute rejection (AR), bronchiolitis obliterans syndrome (BOS) and survival in lung allograft recipients managed with surveillance TBB/BAL (SB) versus those with clinically indicated TBB/BAL (CIB). (nih.gov)
  • With no obvious advantage identified, surveillance bronchoscopy may pose a risk to stable lung transplant recipients. (nih.gov)
  • Infection rates among lung transplant recipients appear to be higher than those encountered in other solid organ transplant populations, likely related to the unique exposure of the lung allograft to the external environment and to the greater magnitude of immunosuppression employed 1 , 2 . (ersjournals.com)
  • The reasons are manifold, including the paucity of both donors and recipients, the investment required in developing paediatric lung transplant centres and scepticism about the outcome. (ersjournals.com)
  • With greater experience and analysis of significant numbers of cases, lung transplant recipients are living longer, and follow-up regimens are becoming streamlined. (medscape.com)
  • Thus, a comprehensive understanding of lung transplantation-related pathology is necessary for both tertiary care pathologists dealing with highly specialized lung transplantation teams and a much larger spectrum of healthcare providers who may be involved in the care of lung transplant recipients or candidates for lung transplantation. (medscape.com)
  • Outcomes after heart and lung transplants have improved, and many recipients survive long enough to develop secondary renal failure, yet remain healthy enough to undergo kidney transplantation. (johnshopkins.edu)
  • Furthermore, renal transplantation reduced the risk of death compared with dialysis by 43% for KAH and 54% for KAL recipients. (johnshopkins.edu)
  • From the total sample, 37% of liver recipients and 20% of lung had cognitive disorders compared to only 9% of heart recipients. (hippokratia.gr)
  • We prospectively measured anti-HLA IgE antibodies in a cohort of kidney (n=60), liver , heart and lung (n=15 each) transplant recipients before and within one-year after transplantation , employing a single- antigen bead assay for HLA class I and class II antigens . (bvsalud.org)
  • Pre-existing anti-HLA IgE antibodies were detected in 10% of renal recipients (including 3.3% IgE -DSA) and in 4.4% of non-renal solid organ transplant recipients ( heart , liver and lung cohort). (bvsalud.org)
  • These data demonstrate that anti-HLA IgE antibodies occur at low frequency in kidney , liver , heart and lung transplant recipients . (bvsalud.org)
  • The airways of CF are susceptible to colonization by respiratory pathogens ( 3 ), a condition that is improved in lung transplant recipients. (cdc.gov)
  • Nevertheless, I. limosus infection has been reported twice in lung transplant recipients ( 4 , 5 ). (cdc.gov)
  • Today, a main focus of the transplant community is the long-term outcomes of lung and heart allograft recipients. (terasaki.org)
  • We mailed questionnaires to surviving Toronto General Hospital lung transplant recipients (n = 190). (creod.on.ca)
  • A total of 117 lung transplant recipients completed the questionnaires (70% response rate). (creod.on.ca)
  • Unfavorable Outcome of Heart Transplantation in Recipients With Type D Personality. (bvsalud.org)
  • In May 2010, the Sixty-third World Health Assembly adopted resolution WHA63.22,1 in which it endorsed the updated WHO Guiding Principles on Human Cell, Tissue and Organ Transplantation and provided strategic directions to support progress in human organ, tissue and cell donation with the aim of maximizing the benefits of transplantation, meeting the needs of recipients, protecting donors and ensuring the dignity of all involved. (who.int)
  • Corneal disease (scarring or perforation) can be successfully addressed through transplantation in 80% of affected individuals.3 Tissue transplantation allows many recipients to return to economically productive lives and promotes their independence. (who.int)
Living-donor3
  • Lastly, Bowdish et al and other groups demonstrated that living-donor lobar lung transplantation can be successfully performed. (medscape.com)
  • Lung transplants can come from a living donor or from someone who has recently died. (msdmanuals.com)
  • Donation from a living donor is possible because the donor can live with one healthy lung. (msdmanuals.com)
Extracorporeal membrane ox1
  • In heart transplant, there is an increase in the number of heart retransplant patients and an increase in patients on extracorporeal membrane oxygenation. (terasaki.org)
Cystic4
  • Transplantation of patients with underlying cystic fibrosis (CF), whose native airways and sinuses are chronically infected with virulent bacterial pathogens, initially raised unique concerns about the potential excessive risk of postoperative infections. (ersjournals.com)
  • The first lung transplantation in an adolescent cystic fibrosis (CF) patient treated at the Department of Paediatrics and Adolescent Medicine within the centre was performed in 1990. (ersjournals.com)
  • A 45-year-old woman in France who had received a lung transplant in 2016 for end-stage cystic fibrosis (CF) sought care for rhinorrhea on March 1, 2022. (cdc.gov)
  • Examples of such disorders and the listings we use to evaluate them include chronic obstructive pulmonary disease ( 103.02 ), chronic lung disease of infancy (also known as bronchopulmonary dysplasia, 103.02C or 103.02E ), pulmonary fibrosis ( 103.02 ), asthma ( 103.02 or 103.03 ), and cystic fibrosis ( 103.04 ). (ssa.gov)
20221
Advanced Lung Disease5
  • A Society that Includes Basic Science, the Failing Heart and Advanced Lung Disease. (ishlt.org)
  • 1 Program for Advanced Lung Disease and Lung Transplantation, Pulmonary and Critical Care Division, Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA. (nih.gov)
  • While offering a vital therapeutic option for patients with advanced lung disease, LTx remains fraught with complications that threaten both the quality and duration of the recipient's life. (ersjournals.com)
  • Montefiore's Advanced Lung Disease Program is the only provider of interstitial lung service and advanced emphysema treatment to our community. (montefiore.org)
  • He performs health services and outcomes research focused on understanding and improving the lives and care of patients with advanced lung disease and is actively involved in clinical trials to improve outcomes in interstitial lung disease. (stanford.edu)
Journal of Heart and Lung Transplantation2
Kidney8
  • We used national data reported to United Network for Organ Sharing (UNOS) to evaluate outcomes of 568 kidney after heart (KAH) and 210 kidney after lung (KAL) transplants performed between 1995 and 2008. (johnshopkins.edu)
  • Median time to kidney transplant was 100.3 months after heart, and 90.2 months after lung transplant. (johnshopkins.edu)
  • anti-HLA IgE in kidney, liver, lung and heart transplantation. (bvsalud.org)
  • Prospective assessment of pre-existing and de novo anti-HLA IgE in kidney, liver, lung and heart transplantation. (bvsalud.org)
  • The long-term survival rates are more than 90% for children's kidney transplantations and about 70% for children's heart and liver transplantations. (hus.fi)
  • Examples of this are heart-lung transplantations, liver and kidney transplantations, and liver and bowel transplantations. (hus.fi)
  • In a kidney transplantation, one of the parents can be the donor. (hus.fi)
  • Kidney transplantation is a far more favourable treatment modality versus dialysis in terms of survival, quality of life and cost-effectiveness. (who.int)
Outcomes3
  • Although one-year survival rates have improved, long-term outcomes for children receiving lung transplants have not (see the image below). (medscape.com)
  • When appropriate, we use minimally invasive lung surgery, including video-assisted thoracoscopic surgery (VATS) and robotic-assisted surgery, to minimize recovery time and improve outcomes. (montefiore.org)
  • Outcomes of corneal transplantation in Europe: report by the European Cornea and Cell Transplantation Registry. (who.int)
Disease26
  • Lung transplantation is a potentially curative therapy for patients with end-stage pulmonary disease. (nature.com)
  • Lung transplantation has matured into an accepted therapeutic alternative for children with end-stage lung disease. (medscape.com)
  • That is, patients trade their end-stage lung disease for transplant lung disease, with the hope that it can be better managed. (medscape.com)
  • Lung transplantation has emerged as an accepted therapy for end-stage lung disease in adult patients, whereas in the paediatric population it is still controversial [ 1 - 3 ]. (ersjournals.com)
  • The cut surface shows the characteristic findings of the disease for which lung transplantation was indicated. (medscape.com)
  • The donor lungs must be disease-free and matched as closely as possible to your tissue type. (medlineplus.gov)
  • Lung transplants may be recommended for people under age 65 who have severe lung disease. (medlineplus.gov)
  • ISHLT is the world's largest multidisciplinary organization dedicated to improving the care of patients with advanced heart or lung disease through transplantation, mechanical circulatory support and innovative therapies. (asaecenter.org)
  • We treat all conditions, from the benign to the malignant, the simple to the complex, with highly trained experts providing disease management and treatment, surgery and transplantation. (montefiore.org)
  • Joshua Mooney, MD, MS, is a board certified pulmonologist and critical care physician who specializes in the care of interstitial lung disease and lung transplant patients. (stanford.edu)
  • At the Johns Hopkins Heart and Vascular Institute, cardiac specialists swiftly translate laboratory discoveries into new treatments, with the ultimate goal of saving more lives from heart disease, the leading cause of death in the United States. (hopkinsmedicine.org)
  • Lung disease treatments. (mayoclinic.org)
  • Home › Occupational Lung Disease › Publications › Factors affecting attainment of paid employment after lung transplantation. (creod.on.ca)
  • The influence of lung disease on the diaphragm has been poorly studied. (frontiersin.org)
  • Lung transplantation (LTx), by replacing a diseased lung with a healthy one, is an interesting model to evaluate the evolution of the diaphragmatic morphology before and after transplantation in the context of lung disease. (frontiersin.org)
  • Call 310-825-9011 to learn more about adult congenital heart disease treatment. (uclahealth.org)
  • The Ahmanson/UCLA Adult Congenital Heart Disease Center is the first and one of the largest facilities of its kind in the United States. (uclahealth.org)
  • The center is a tertiary care national and international resource that provides services to the growing number of patients with congenital heart disease who reach adulthood. (uclahealth.org)
  • We are pleased to announce the creation of the Adolescent/Young Adult Transitional Care Program, for Congenital Heart Disease . (uclahealth.org)
  • The program is the combined efforts of the Division of Pediatric Cardiology and the Ahmanson/UCLA Adult Congenital Heart Disease Center. (uclahealth.org)
  • The program provides comprehensive treatment of adolescents with congenital heart disease, ages 15 to 20. (uclahealth.org)
  • Patients who are new to the Ahmanson/UCLA Adult Congenital Heart Disease Center should ideally have their doctor's mail or fax in cardiac related medical records prior to scheduling an appointment. (uclahealth.org)
  • CLD means chronic lung disease of infancy. (ssa.gov)
  • A heart transplant may be considered when a person has severe heart disease and is likely to benefit most from a donor heart. (healthlinkbc.ca)
  • The person has end-stage heart failure, ischemic heart disease, cardiomyopathy, or congenital heart disease. (healthlinkbc.ca)
  • The patient presented remarkable adulta clinical improvement to dyspnea, she was discharged with medical reference to the Adult Congenital Heart Disease clinic at Rosales National Hospital. (bvsalud.org)
Field of lung transplantation2
  • However, the phrase "children are not just small adults" is nowhere more true than in the field of lung transplantation. (medscape.com)
  • Surgical advances, in conjunction with more effective immunosuppressive strategies, have propelled the field of lung transplantation forward and have made intermediate-term survival an achievable goal. (ersjournals.com)
Pediatric3
  • Following a steady increase in pediatric lung transplants in the first decade of this millennium, with 125 reported to the ISHLT registry in 2009, numbers have remained stable with a range of 90 to 137 observed during the past 12 years. (medscape.com)
  • Pediatric lung transplantation actuarial survival by era. (medscape.com)
  • According to the International Society of Heart and Lung Transplantation (ISHLT) Registry, 2,330 pediatric lung and 730 pediatric heart-lung transplants have been performed through June 30, 2016. (medscape.com)
Congenital5
  • Supporting congenital heart patients through adulthood. (ctsurgerypatients.org)
  • First successful "blue baby operation" in the world to correct congenital heart defects. (hopkinsmedicine.org)
  • When a transplantation is indicated, it is often because of a congenital structural defect or condition where the need for a transplant becomes evident in the first few months of life. (hus.fi)
  • The most common indications for transplantation are congenital nephrotic syndrome (CNF), congenital malformations of the urinary tract and other congenital conditions. (hus.fi)
  • The transplantation of human tissues, organs or cells is an established form of treatment that has been acknowledged as the best and very often only life-saving therapy for several serious and life-threatening congenital, inherited and acquired diseases and injuries. (who.int)
Survival17
  • 1 Nevertheless, the overall survival after a lung transplant is still inferior compared to other solid-organ transplantation modalities. (nature.com)
  • 12 These results supported that potential gut microbiome-targeted interventions could influence the survival of patients received solid organ transplantation. (nature.com)
  • Two recent series from North American centres with extensive experience in transplantation of CF patients have documented 1-yr survival rates of 50% versus 83% and 67% versus 96% among CF patients with and without B. cepacia , respectively 7 , 8 . (ersjournals.com)
  • Lung transplantation in adults is an accepted therapeutic option, whereas there is ongoing debate on its positive impact on survival in children. (ersjournals.com)
  • Analysing different eras of transplantation suggests an improvement over the years with a 5-yr survival rate of 70.6% in the second decade. (ersjournals.com)
  • A high rate of successful re-transplantation prolonged total patient survival. (ersjournals.com)
  • Survival after lung transplantation is still well below that of transplantation of other solid organs but has increased over the past decades [ 2 , 5 - 7 ]. (ersjournals.com)
  • The subgroup of children and adolescents has been repeatedly reported to have poorer results [ 3 , 6 - 8 ], leading to ongoing discussion on the beneficial effect of lung transplantation on survival in these patients [ 2 , 3 , 6 ]. (ersjournals.com)
  • There are of course associated risks with transplantation, and while the early survival rates after the transplant are good, there can be no guarantees that any particular transplant will be a success. (gosh.nhs.uk)
  • Since 2003, survival in children after lung or heart-lung transplant has significantly improved at GOSH, giving a survival of over 70 per cent at five years, and an estimated survival of more than 50 per cent by seven years. (gosh.nhs.uk)
  • CT12 Chapter 5: Factors Affecting Graft Survival Within 1-year Post-Transplantation in Heart and Lung Transplant: An Analysis of the OPTN/UNOS Registry. (terasaki.org)
  • Factors Affecting Graft Survival Within 1-year Post-Transplantation in Heart and Lung Transplant: An Analysis of the OPTN/UNOS Registry. (terasaki.org)
  • Given that sicker/riskier patients are now receiving more heart and lung transplants, future studies need to take place to better understand these patients so that they can have the same survival as patients entering transplant with less severe illnesses. (terasaki.org)
  • The doctor strongly expects that a heart transplant will increase survival and improve the person's quality of life. (healthlinkbc.ca)
  • Survival Trend Seen With LVAD in Advanced Heart Failure Some patients with advanced heart failure not on the transplantation wait list might benefit from an LVAD, but robust evidence is lacking on the optimal management of patients in this 'grey zone. (medscape.com)
  • The benefits of human tissue transplantation can be seen in both children and adults, including in survival rates following severe burn trauma, recovery of movement, closure of chronic wounds, rehabilitation of heart function and restoration of sight. (who.int)
  • Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation that is associated with poor survival. (bvsalud.org)
ISHLT2
Organ transplantations3
  • The New Children's Hospital manages all organ transplantations for children in Finland. (hus.fi)
  • The indications for organ transplantations in children differ from those in adults. (hus.fi)
  • We mainly use organs donated by adults for children's organ transplantations. (hus.fi)
Detection of allograft dysfunction2
  • Role of pulmonary function in the detection of allograft dysfunction after heart-lung transplantation. (bmj.com)
  • The sensitivity, specificity, and positive/negative predictive values (PPV and NPV) of lung function for the detection of allograft dysfunction in these patients were measured. (bmj.com)
20161
  • 3 Global Observatory on Donation and Transplantation 2016. (who.int)
Bilateral2
  • Double lung transplant (sometimes called bilateral lung transplant) - In this operation a patient receives two lungs. (gosh.nhs.uk)
  • Results of single-lung transplantation for bilateral pulmonary fibrosis. (medigraphic.com)
Diseases4
Infection8
  • BACKGROUND: Lung function is altered by infection and rejection in patients who undergo heart-lung transplantation. (bmj.com)
  • Infection and rejection were accompanied by airflow obstruction, a rise in the slopes of the alveolar plateaus for nitrogen, hexafluoride sulphur and helium (SN2, SSF6, and SHe), and a decrease in the difference between SSF6 and SHe (delta S), total lung capacity (TLC), and lung transfer factor (TLCO). (bmj.com)
  • CONCLUSIONS: Indices of ventilation distribution, FEF25-75, and TLC have the best optimal sensitivity for the diagnosis of infection and rejection after heart-lung transplantation. (bmj.com)
  • Infection is an ever-present threat to the well-being of the lung transplant recipient and is a leading cause of both early and late mortality. (ersjournals.com)
  • Clinical features of lung transplantation-related pathology can range from an absence of symptoms to signs and symptoms of respiratory distress and/or infection and are not detailed in this article. (medscape.com)
  • Although aimed at protecting the host from infection, in the context of transplantation, this injury leads to allograft rejection. (medscape.com)
  • We report a case of I. limosus bacteremia in a patient in France who received a lung transplant and experienced chronic graft dysfunction and SARS-CoV-2 infection. (cdc.gov)
  • Fungus may be inhaled and cause lung infection. (columbiasurgery.org)
Rejection13
  • 11 , 12 Compelling evidences have also showed that the gut microbiome could modulate alloimmunity and rejection, directly implicating the gut microbiome as a therapeutic target in organ transplantation. (nature.com)
  • This article will review the major medical complications, excluding allograft rejection, which may be encountered in the lung transplant recipient. (ersjournals.com)
  • In addition toallograft rejection (a topic covered elsewhere in this series), a multitude of medical complications mark the post-transplantation course. (ersjournals.com)
  • Lung transplantation-related pathology encompasses a spectrum of disorders that include, but are not limited to, indications for lung transplantation (seen in explanted lungs), surgical complications (airway anastomotic and vascular complications), ischemia-reperfusion injury, rejection (acute and chronic), infections, and posttransplantation lymphoproliferative disorders (PTLDs). (medscape.com)
  • Rejection of the new lung, which may happen right away, within the first 4 to 6 weeks, or over time. (medlineplus.gov)
  • Antibody mediated rejection (ABMR) is a major factor limiting outcome after organ transplantation . (bvsalud.org)
  • Urinary thromboxane B2 as an indicator of acute rejection in lung allotransplantation. (medigraphic.com)
  • Thromboxane B2 and lung transplantation: Correlation of rejection with levels detected in bronchoalveolar lavage. (medigraphic.com)
  • Urinary thromboxane B2 excretion during acute rejection in cyclosporine treated experimental lung allotransplantation. (medigraphic.com)
  • This includes regular sampling (biopsies) of the transplanted heart tissue to check for rejection. (healthlinkbc.ca)
  • Rejection of the donor heart. (healthlinkbc.ca)
  • To check for rejection, surgeons will regularly test a sample (biopsy) of the heart tissue. (healthlinkbc.ca)
  • Donor-Derived DNA Predicts Lung Transplant Rejection Before any clinical signs of graft failure are evident in patients who undergo lung transplant, experimental research suggests that donor-derived cell-free DNA could help predict a poor outcome. (medscape.com)
Complications1
  • The indications for transplantation, the pharmacokinetics of immunosuppressants, and the complications of transplantation can be strikingly different for children compared with their adult counterparts. (medscape.com)
Mortality1
  • The study will compare the time to a composite endpoint of relative decline in lung function [10% relative decline in forced vital capacity (FVC), first respiratory hospitalization, lung transplantation, or all-cause mortality] The secondary objectives will be to examine the effect of NAC on the components of the primary composite endpoint, the rates of clinical events, change in physiology, change in health status, and change in respiratory symptoms. (stanford.edu)
19883
Chronic4
  • Working closely with Montefiore's new COVID-19 Recovery (CORE) clinic, we provide follow-up and recovery lung care to patients who had COVID-19, addressing ongoing symptoms and chronic conditions, as well as any new issues that arise. (montefiore.org)
  • We also use listings in this body system to evaluate respiratory failure resulting from an underlying chronic respiratory disorder ( 103.04E or 103.14 ) and lung transplantation ( 103.11 ). (ssa.gov)
  • Organ transplantation is often the best, if not the only, treatment for acute and chronic organ failure. (who.int)
  • For chronic or acute liver failure, as well as some cardiorespiratory conditions, the only alternative to transplantation is death. (who.int)
Double lung5
Donation and Transplantation3
  • In June 2018, the Secretariat established the WHO Task Force on Donation and Transplantation of Human Organs and Tissues as an advisory group composed of experts from all WHO regions. (who.int)
  • Organ and tissue donation and transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ or tissue. (who.int)
  • 5 United Nations General Assembly - Resolution A/RES/71/322 on Strengthening and promoting effective measures and international cooperation on organ donation and transplantation to prevent and combat trafficking in persons for the purpose of organ removal and trafficking in human organs, September 2017. (who.int)
Donors2
Surgery10
  • The Department for Thoracic Surgery at the Medical University of Vienna (Vienna, Austria) is one of the largest lung transplant centres in Europe, with the highest per head transplantation rate worldwide (14.1 per million inhabitants) [ 9 ]. (ersjournals.com)
  • Lung transplant is surgery to replace one or both diseased lungs with healthy lungs from a human donor. (medlineplus.gov)
  • During lung transplant surgery, you are asleep and pain-free (under general anesthesia ). (medlineplus.gov)
  • Lung transplant surgery is often done with the use of a heart-lung machine. (medlineplus.gov)
  • This device does the work of your heart and lungs while your heart and lungs are stopped for the surgery. (medlineplus.gov)
  • We work with clinicians in the Department of Surgery and the Corrigan Minehan Heart Center to recommend the best anesthetic services for patients undergoing all types of cardiac procedures. (massgeneral.org)
  • In the first month following lung transplantation you will be recovering from the stress of surgery. (columbiasurgery.org)
  • A randomized trial comparing lung-volume- reduction surgery with medical therapy for severe emphysema. (medigraphic.com)
  • To prevent the body from rejecting the donor heart, your surgeon will give you powerful drugs (immunosuppressants) right after surgery. (healthlinkbc.ca)
  • This is because some of the nerves that control your heart were cut during your surgery. (healthlinkbc.ca)
Surgical4
  • Lung transplantation is the surgical removal of a healthy lung or part of a lung from a living person and then its transfer into someone whose lungs no longer function. (msdmanuals.com)
  • When providing surgical oncology interventions for lung cancer patients, our collaborative approach extends to include our Montefiore Einstein Cancer Center. (montefiore.org)
  • Our surgical team complements radiation oncology and medical oncology treatments to provide the most comprehensive lung cancer care available. (montefiore.org)
  • Surgical options are limited to heart transplantation. (medscape.com)
Renal1
  • He survived for 18 days after transplantation and died of renal failure. (medscape.com)
Organs2
  • Overview of Transplantation Transplantation is the removal of living, functioning cells, tissues, or organs from the body and then their transfer back into the same body or into a different body. (msdmanuals.com)
  • Replacement with a healthy lung can promote the recovery of the diaphragm to its anatomical morphology, reinforcing the close relationship between these two organs. (frontiersin.org)
Pulmonary hypertension1
  • Pulmonary Hypertension Pulmonary hypertension is a condition in which blood pressure in the arteries of the lungs (the pulmonary arteries) is abnormally high. (msdmanuals.com)
Ischemia-reperfusion injury1
  • Improved understanding of the mechanism of lung injury during brain death and during transition from donor to recipient may one day lead to techniques and preservation solutions that prevent ischemia-reperfusion injury. (medscape.com)
Emphysema1
  • Emphysema is end stage and generalized by the time the patient needs transplantation. (medscape.com)
20171
Bronchoscopy2
  • For patient education resources, see the Lung and Airway Center , as well as Heart and Lung Transplant and Bronchoscopy . (medscape.com)
  • A multi-center, controlled trial is required to validate the utility and safety of surveillance bronchoscopy in lung transplantation. (nih.gov)
Cardiac2
  • The Cardiac Anesthesia Division provides comprehensive, quality treatment for patients undergoing care through the Corrigan Minehan Heart Center. (massgeneral.org)
  • Located within the Texas Medical Center in Houston, Texas, and founded in 1962 by renowned cardiac surgeon Denton Cooley, The Texas Heart Institute's doctors, scientists, and engineers are bringing the future of cardiovascular care to life. (texasheart.org)
Surgeons4
  • Our program includes a team of pulmonologists, lung surgeons, lung transplant surgeons and more, working together in one place, under one leader. (montefiore.org)
  • The world-renowned physicians and surgeons of the Comprehensive Lung Program are an expert, multidisciplinary team. (montefiore.org)
  • Mayo Clinic pulmonologists, lung transplant surgeons and other specialists research lung transplant and other treatments for lung conditions. (mayoclinic.org)
  • Wildevuur CR, Benfield JR. A review of 23 human lung transplantations by 20 surgeons. (medigraphic.com)
Underwent1
19832
  • Joel Cooper, MD, at the University of Toronto achieved success in 1983 with the transplantation of a single lung. (medscape.com)
  • Since the first successful lung transplant following the implementation of cyclosporin in 1983, the number of lung transplants performed worldwide has increased to approximately 2,500 per year [ 4 ]. (ersjournals.com)
Single Lung Transplant1
  • Single Lung Transplant - In this operation a patient receives one lung (left or right), although this is rarely carried out in children. (gosh.nhs.uk)
Procedures2
  • Paediatric lung transplantation had scarcely been performed until the 1990s and even today represents only a minority of total procedures performed, accounting for up to approximately 80 procedures per year worldwide [ 5 ]. (ersjournals.com)
  • Below is a list summarizing the CPT codes for heart/lung transplantation procedures. (codingahead.com)
Computed tomography1
  • The study aimed to evaluate the diaphragm morphology (height and thickness) in single-lung transplantation (SLTx), using computed tomography (CT), by assessing the evolution of the hemidiaphragm of the transplanted and the native side. (frontiersin.org)
Respiratory3
  • The possibility that the microbiota of the lower respiratory tract may have local effects following lung transplantation has been widely reported. (nature.com)
  • We evaluate respiratory disorders that result in obstruction (difficulty moving air out of the lungs) or restriction (difficulty moving air into the lungs), or that interfere with diffusion (gas exchange) across cell membranes in the lungs. (ssa.gov)
  • The International Society for Heart and Lung Transplantation, American Thoracic Society, and European Respiratory Society convened a committee of international experts to describ. (bvsalud.org)
Microbiome1
  • Indeed, the lung graft microbiome is affected by donor and recipient factors ( 6 ), but early posttransplant infections mainly involve the bacteria of the recipient rather than those of the donor ( 7 ). (cdc.gov)
Tissues2
  • CPT 33933 describes the standard backbench preparation of a cadaver donor heart/lung allograft before transplantation, including the dissection of the allograft from surrounding soft tissues to prepare the aorta, superior vena cava, inferior vena cava, and trachea for implantation. (codingahead.com)
  • Thus, the availability of and access to human tissues for transplantation remains essential. (who.int)
Transplant is done1
  • In most cases, a lung transplant is done only after all other treatments for lung failure are unsuccessful. (medlineplus.gov)
Post-transplant1
  • In this chapter, we review the experience of heart and lung transplantation as reported to the Organ Procurement Transplant Network/United Network of Organ Sharing registry and investigate the factors responsible for causing failure in the first post-transplant year. (terasaki.org)
19632