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  • acute
  • agranulocytosis (ă-gran-yoo-loh-sy- toh -sis) n. a disorder in which there is a severe acute deficiency of certain blood cells (neutrophils) as a result of damage to the bone marrow by toxic drugs or chemicals. (encyclopedia.com)
  • A certain subtype of leukaemia called T- cell acute lymphoblastic leukaemia (T-ALL) often affects the thymus gland, a small organ located in the upper chest. (leukaemiacare.org.uk)
  • bones
  • Think of carrots as orange wonder wands-their stellar calorie-to-fiber ratio keeps your belly flat, their calcium helps keep your bones strong, and their vitamin A content reduces the development of skin cancer cells. (eatthis.com)
  • Bone marrow is found in the center of some bones. (ahealthyme.com)
  • Spongy bone is found mostly at the ends of bones and contains red marrow. (cancer.gov)
  • Bone marrow is found in the center of most bones and has many blood vessels. (cancer.gov)
  • This means that there are myeloma cells present in your body, but they're not progressing or causing any damage to your bones or kidneys. (healthline.com)
  • Biopsy
  • In addition to a medical history and physical exam, health care providers use blood tests, a bone marrow biopsy, and cytogenic analysis to diagnose aplastic anemia or MDS. (nih.gov)
  • If the ANC level is abnormal, the doctor may recommend further testing, such as a bone marrow biopsy or genetic blood tests to determine what is causing the agranulocytosis. (medicalnewstoday.com)
  • affects
  • Neurofibromatosis type 1 (also called von Recklinghausen disease) affects the development and growth of nerve cells (called neurons) and causes tumours to grow on nerves. (cancer.ca)
  • Shwachman-Diamond syndrome affects many parts of the body, including the bone marrow, pancreas and skeletal system. (cancer.ca)
  • It affects bone marrow, causing it to produce large numbers of abnormal white blood cells. (epnet.com)
  • This is known as SVC syndrome, and if it affects blood flow out of the brain it can cause headaches, dizziness and feelings of confusion. (leukaemiacare.org.uk)
  • proteins
  • A machine takes the excess proteins from the blood. (redorbit.com)
  • Led by principal investigator Catriona H. M. Jamieson, MD, PhD, associate professor of medicine and director of stem cell research at UC San Diego Moores Cancer Center, the researchers found that a compound called sabutoclax appears to selectively target LSCs that express particular protein isoforms through alternatively splicing, a fundamental process in which a gene is able to code for multiple proteins. (regenerativemedicine.net)
  • Of clinical importance, they noted that sabutoclax, which suppresses all BCL2 anti-apoptotic proteins, renders these marrow-dwelling blast crisis LSCs sensitive and more susceptible to TKI-based therapeutics at doses that do not harm normal progenitor cells. (regenerativemedicine.net)
  • It's based on the level of calcium in a person's blood along with the proteins hemoglobin and monoclonal immunoglobulin. (healthline.com)